Danio rerio

0 known processes

tlr8b

toll-like receptor 8b

(Aliases: TIR8.1)

tlr8b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein transport GO:0051223 3 0.091
i kappab kinase nf kappab signaling GO:0007249 4 0.077
protein localization to nucleus GO:0034504 3 0.075
dicarboxylic acid transport GO:0006835 1 0.075
response to stress GO:0006950 263 0.074
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.072
nuclear transport GO:0051169 4 0.070
aging GO:0007568 2 0.067
wound healing GO:0042060 90 0.066
generation of neurons GO:0048699 385 0.064
neuron differentiation GO:0030182 353 0.064
cellular response to external stimulus GO:0071496 2 0.063
response to amino acid GO:0043200 2 0.062
response to drug GO:0042493 3 0.060
positive regulation of cytokine production GO:0001819 2 0.056
single fertilization GO:0007338 3 0.055
positive regulation of transport GO:0051050 2 0.055
signal transduction GO:0007165 455 0.054
protein targeting to nucleus GO:0044744 3 0.054
morphogenesis of an epithelium GO:0002009 333 0.054
nucleocytoplasmic transport GO:0006913 4 0.052
regulation of protein targeting GO:1903533 2 0.051
protein import GO:0017038 3 0.050
regulation of cytoplasmic transport GO:1903649 4 0.050
positive regulation of immune effector process GO:0002699 3 0.049
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.049
response to abiotic stimulus GO:0009628 122 0.047
regulation of response to stimulus GO:0048583 269 0.046
chloride transmembrane transport GO:1902476 4 0.046
exocytosis GO:0006887 1 0.046
response to external stimulus GO:0009605 264 0.046
cell surface receptor signaling pathway GO:0007166 325 0.046
regulation of production of molecular mediator of immune response GO:0002700 1 0.045
regulation of nucleocytoplasmic transport GO:0046822 2 0.044
regulation of wound healing GO:0061041 2 0.044
regulation of intracellular protein transport GO:0033157 3 0.044
transport GO:0006810 220 0.041
protein import into nucleus GO:0006606 3 0.040
establishment of protein localization to organelle GO:0072594 4 0.040
regulation of establishment of protein localization GO:0070201 4 0.040
single organism nuclear import GO:1902593 3 0.040
larval development GO:0002164 2 0.039
neurological system process GO:0050877 62 0.038
regulation of protein import into nucleus GO:0042306 2 0.038
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.037
stem cell proliferation GO:0072089 4 0.037
nuclear import GO:0051170 3 0.037
response to carbohydrate GO:0009743 3 0.036
inorganic anion transport GO:0015698 25 0.035
anion transport GO:0006820 38 0.035
single organism localization GO:1902578 225 0.035
protein complex localization GO:0031503 1 0.035
regulation of developmental process GO:0050793 247 0.035
regulation of cellular amine metabolic process GO:0033238 0 0.034
regulation of reactive oxygen species metabolic process GO:2000377 2 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
amine metabolic process GO:0009308 2 0.034
regulation of signal transduction GO:0009966 225 0.033
regulation of protein localization to nucleus GO:1900180 2 0.033
multicellular organismal metabolic process GO:0044236 2 0.032
negative regulation of biological process GO:0048519 304 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
central nervous system development GO:0007417 387 0.031
protein secretion GO:0009306 1 0.031
toll like receptor signaling pathway GO:0002224 4 0.031
immune system development GO:0002520 191 0.031
cellular amine metabolic process GO:0044106 2 0.031
heart development GO:0007507 313 0.031
response to corticosteroid GO:0031960 1 0.031
positive regulation of jnk cascade GO:0046330 3 0.031
defense response to bacterium GO:0042742 22 0.030
eye development GO:0001654 277 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
regulation of cytokine production GO:0001817 3 0.029
homeostatic process GO:0042592 142 0.029
adherens junction organization GO:0034332 4 0.028
regulation of biological quality GO:0065008 263 0.028
single organism transport GO:0044765 206 0.028
autophagy GO:0006914 4 0.028
defense response to other organism GO:0098542 33 0.028
cellular ketone metabolic process GO:0042180 11 0.028
fertilization GO:0009566 3 0.028
blood vessel development GO:0001568 246 0.028
immune system process GO:0002376 241 0.027
cellular component morphogenesis GO:0032989 336 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
positive regulation of wound healing GO:0090303 1 0.027
b cell activation GO:0042113 2 0.027
response to chemical GO:0042221 320 0.027
cation transmembrane transport GO:0098655 65 0.026
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.026
antimicrobial humoral response GO:0019730 2 0.026
maintenance of location GO:0051235 4 0.026
production of molecular mediator of immune response GO:0002440 2 0.026
hematopoietic or lymphoid organ development GO:0048534 191 0.026
cellular response to biotic stimulus GO:0071216 3 0.026
cellular protein catabolic process GO:0044257 4 0.026
amino acid transport GO:0006865 2 0.025
positive regulation of map kinase activity GO:0043406 3 0.025
monovalent inorganic cation transport GO:0015672 42 0.025
ion transport GO:0006811 114 0.025
regulation of blood coagulation GO:0030193 1 0.025
sensory organ morphogenesis GO:0090596 200 0.025
tube morphogenesis GO:0035239 349 0.025
regulation of blood vessel size GO:0050880 2 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
response to other organism GO:0051707 97 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
establishment of localization GO:0051234 244 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
multicellular organismal macromolecule metabolic process GO:0044259 2 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
programmed cell death GO:0012501 119 0.024
death GO:0016265 121 0.024
cellular component biogenesis GO:0044085 178 0.024
lymphocyte proliferation GO:0046651 1 0.024
cell substrate adhesion GO:0031589 4 0.024
protein heterooligomerization GO:0051291 1 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
positive regulation of cell activation GO:0050867 1 0.023
gtp metabolic process GO:0046039 4 0.023
leukocyte proliferation GO:0070661 1 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
response to monosaccharide GO:0034284 3 0.023
multi organism process GO:0051704 134 0.023
angiogenesis GO:0001525 158 0.023
cation transport GO:0006812 81 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
sensory organ development GO:0007423 393 0.022
small molecule metabolic process GO:0044281 77 0.022
blood coagulation GO:0007596 12 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
muscle structure development GO:0061061 196 0.021
synaptic transmission cholinergic GO:0007271 4 0.021
regulation of tube size GO:0035150 2 0.021
cytokinesis GO:0000910 3 0.021
negative regulation of cellular process GO:0048523 283 0.021
chordate embryonic development GO:0043009 271 0.021
head development GO:0060322 303 0.021
response to glucose GO:0009749 3 0.021
multicellular organism growth GO:0035264 4 0.021
cellular component movement GO:0006928 335 0.021
phagocytosis GO:0006909 3 0.021
digestive system development GO:0055123 289 0.020
b cell mediated immunity GO:0019724 3 0.020
embryonic organ development GO:0048568 381 0.020
developmental growth GO:0048589 166 0.020
regulation of cell activation GO:0050865 1 0.020
positive regulation of stress activated mapk cascade GO:0032874 3 0.020
protein acetylation GO:0006473 2 0.020
superoxide metabolic process GO:0006801 2 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
positive regulation of secretion GO:0051047 1 0.020
apoptotic process GO:0006915 116 0.019
cellular response to starvation GO:0009267 1 0.019
system process GO:0003008 185 0.019
startle response GO:0001964 4 0.019
regulation of glucose transport GO:0010827 1 0.019
positive regulation of translation GO:0045727 1 0.019
vasculature development GO:0001944 278 0.019
regulation of metabolic process GO:0019222 359 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
blood vessel morphogenesis GO:0048514 216 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
collagen metabolic process GO:0032963 2 0.019
regulation of reproductive process GO:2000241 4 0.019
cell projection organization GO:0030030 284 0.019
brain development GO:0007420 293 0.019
hemostasis GO:0007599 13 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
skeletal muscle organ development GO:0060538 78 0.018
astrocyte differentiation GO:0048708 1 0.018
positive regulation of cell cycle GO:0045787 3 0.018
cell projection morphogenesis GO:0048858 244 0.018
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
mononuclear cell proliferation GO:0032943 1 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
gtp catabolic process GO:0006184 2 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
response to alkaloid GO:0043279 2 0.018
response to organic cyclic compound GO:0014070 51 0.018
single organism organelle organization GO:1902589 199 0.018
muscle cell differentiation GO:0042692 139 0.018
adult behavior GO:0030534 2 0.018
regulation of stem cell differentiation GO:2000736 4 0.018
cellular response to nutrient levels GO:0031669 2 0.017
response to hexose GO:0009746 3 0.017
response to nutrient GO:0007584 3 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
ion transmembrane transport GO:0034220 91 0.017
cell death GO:0008219 121 0.017
interspecies interaction between organisms GO:0044419 4 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
locomotion GO:0040011 313 0.017
transmembrane transport GO:0055085 120 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
cell morphogenesis GO:0000902 289 0.017
coagulation GO:0050817 13 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
localization of cell GO:0051674 244 0.017
positive regulation of catabolic process GO:0009896 4 0.017
regulation of cell shape GO:0008360 1 0.017
cell matrix adhesion GO:0007160 4 0.017
taxis GO:0042330 109 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
cellular biosynthetic process GO:0044249 286 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
hemopoiesis GO:0030097 183 0.016
digestive tract development GO:0048565 265 0.016
cation homeostasis GO:0055080 33 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of binding GO:0051098 3 0.016
rna metabolic process GO:0016070 219 0.016
response to external biotic stimulus GO:0043207 97 0.016
peptide transport GO:0015833 1 0.016
immune response GO:0006955 28 0.016
negative regulation of catabolic process GO:0009895 3 0.016
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
neuroblast proliferation GO:0007405 2 0.016
regulation of circadian rhythm GO:0042752 4 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
response to hydrogen peroxide GO:0042542 3 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
regulation of protein catabolic process GO:0042176 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
ameboidal type cell migration GO:0001667 143 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
type i interferon production GO:0032606 2 0.015
glucose import GO:0046323 2 0.015
regulation of protein complex assembly GO:0043254 3 0.015
defense response GO:0006952 47 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
positive regulation of cellular process GO:0048522 201 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
regulation of signaling GO:0023051 235 0.015
cell proliferation GO:0008283 80 0.015
membrane hyperpolarization GO:0060081 1 0.015
macromolecule localization GO:0033036 54 0.015
growth GO:0040007 174 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
regulation of mrna processing GO:0050684 3 0.014
chemical homeostasis GO:0048878 49 0.014
cellular localization GO:0051641 97 0.014
neuron development GO:0048666 262 0.014
myeloid cell differentiation GO:0030099 86 0.014
embryonic hemopoiesis GO:0035162 53 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
response to mechanical stimulus GO:0009612 24 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
striated muscle cell differentiation GO:0051146 129 0.014
regulation of programmed cell death GO:0043067 101 0.014
negative regulation of cytokine production GO:0001818 1 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
ear development GO:0043583 127 0.014
regulation of inflammatory response GO:0050727 2 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
nucleic acid metabolic process GO:0090304 244 0.014
regulation of cell differentiation GO:0045595 142 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
gene expression GO:0010467 252 0.014
membrane invagination GO:0010324 1 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
determination of left right symmetry GO:0007368 179 0.014
cell killing GO:0001906 2 0.014
response to vitamin GO:0033273 3 0.014
female sex differentiation GO:0046660 4 0.014
protein acylation GO:0043543 3 0.014
response to bacterium GO:0009617 58 0.014
regulation of synapse organization GO:0050807 3 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
calcium mediated signaling GO:0019722 2 0.013
protein localization to plasma membrane GO:0072659 1 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
glucose homeostasis GO:0042593 1 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
positive regulation of biological process GO:0048518 253 0.013
regulation of gtpase activity GO:0043087 2 0.013
sleep GO:0030431 1 0.013
rna localization GO:0006403 4 0.013
response to glucocorticoid GO:0051384 1 0.013
detection of stimulus GO:0051606 29 0.013
sodium ion transport GO:0006814 24 0.013
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
meiotic cell cycle process GO:1903046 3 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
protein metabolic process GO:0019538 183 0.013
cell motility GO:0048870 244 0.013
mitotic cytokinesis GO:0000281 3 0.013
eye morphogenesis GO:0048592 144 0.013
biosynthetic process GO:0009058 294 0.013
endosomal transport GO:0016197 2 0.013
erythrocyte homeostasis GO:0034101 55 0.013
regulation of postsynaptic membrane potential GO:0060078 1 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
septum transversum development GO:0003343 4 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
regulation of cell death GO:0010941 103 0.013
positive regulation of leukocyte mediated immunity GO:0002705 1 0.013
zymogen activation GO:0031638 3 0.013
mitochondrion organization GO:0007005 4 0.013
regulation of apoptotic process GO:0042981 98 0.013
cellular component assembly GO:0022607 170 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
somatic muscle development GO:0007525 4 0.012
organic acid metabolic process GO:0006082 31 0.012
regulation of autophagy GO:0010506 3 0.012
camera type eye development GO:0043010 222 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
membrane fusion GO:0061025 2 0.012
single organism metabolic process GO:0044710 217 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
neurotransmitter transport GO:0006836 2 0.012
digestive tract morphogenesis GO:0048546 231 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
cellular response to reactive oxygen species GO:0034614 2 0.012
regulation of response to stress GO:0080134 36 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
muscle organ development GO:0007517 101 0.012
response to uv GO:0009411 3 0.012
positive regulation of cell killing GO:0031343 2 0.012
regulation of immune system process GO:0002682 34 0.012
collagen biosynthetic process GO:0032964 2 0.012
interferon beta production GO:0032608 1 0.012
heterocycle metabolic process GO:0046483 290 0.012
inorganic cation transmembrane transport GO:0098662 50 0.012
response to biotic stimulus GO:0009607 97 0.012
positive regulation of cell division GO:0051781 2 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
protein polymerization GO:0051258 4 0.012
cellular protein metabolic process GO:0044267 129 0.012
lipid storage GO:0019915 1 0.012
response to organic substance GO:0010033 153 0.012
anion transmembrane transport GO:0098656 12 0.012
neuron projection morphogenesis GO:0048812 161 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
actin cytoskeleton organization GO:0030036 63 0.012
regulation of glucose import GO:0046324 1 0.012
cellular response to stress GO:0033554 62 0.012
regulation of cell communication GO:0010646 232 0.012
muscle cell development GO:0055001 115 0.012
positive regulation of gliogenesis GO:0014015 2 0.012
regulation of membrane potential GO:0042391 23 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
activation of mapk activity GO:0000187 3 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
neurotransmitter secretion GO:0007269 2 0.011
positive regulation of cytokine biosynthetic process GO:0042108 1 0.011
intracellular signal transduction GO:0035556 85 0.011
female gonad development GO:0008585 4 0.011
regulation of hemostasis GO:1900046 1 0.011
neuron projection development GO:0031175 180 0.011
regulation of leukocyte mediated immunity GO:0002703 1 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
hindbrain development GO:0030902 91 0.011
cellular protein modification process GO:0006464 100 0.011
antibacterial humoral response GO:0019731 2 0.011
phosphorylation GO:0016310 69 0.011
nuclear export GO:0051168 1 0.011
behavior GO:0007610 74 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
regulation of metal ion transport GO:0010959 4 0.011
synaptic transmission glycinergic GO:0060012 1 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
regulation of dna replication GO:0006275 3 0.011
regulation of cell killing GO:0031341 2 0.011
ion homeostasis GO:0050801 41 0.011
cell migration GO:0016477 237 0.011
response to decreased oxygen levels GO:0036293 25 0.011
regulation of dendrite development GO:0050773 3 0.011
regulation of endopeptidase activity GO:0052548 23 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
single organism biosynthetic process GO:0044711 71 0.011
regulation of ph GO:0006885 3 0.011
axonogenesis GO:0007409 152 0.011
biological adhesion GO:0022610 40 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
blood circulation GO:0008015 87 0.011
neural retina development GO:0003407 49 0.011
immune effector process GO:0002252 23 0.010
regulation of calcium ion transport GO:0051924 2 0.010
regulation of cytokine biosynthetic process GO:0042035 1 0.010
reactive oxygen species metabolic process GO:0072593 6 0.010
regulation of synapse assembly GO:0051963 3 0.010
embryonic heart tube development GO:0035050 133 0.010
anterior posterior pattern specification GO:0009952 152 0.010
cognition GO:0050890 1 0.010
phagocytosis engulfment GO:0006911 1 0.010
positive regulation of neuron apoptotic process GO:0043525 1 0.010
negative regulation of protein transport GO:0051224 3 0.010
positive regulation of innate immune response GO:0045089 8 0.010
regulation of primary metabolic process GO:0080090 311 0.010
protein targeting to membrane GO:0006612 1 0.010
cytokinetic process GO:0032506 2 0.010
peptidyl serine modification GO:0018209 2 0.010
regeneration GO:0031099 91 0.010
response to oxygen levels GO:0070482 25 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
sequestering of metal ion GO:0051238 3 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
response to endogenous stimulus GO:0009719 83 0.010
negative regulation of multi organism process GO:0043901 3 0.010
tissue regeneration GO:0042246 74 0.010
response to radiation GO:0009314 51 0.010
intestinal absorption GO:0050892 2 0.010
hepaticobiliary system development GO:0061008 98 0.010
positive regulation of signal transduction GO:0009967 56 0.010

tlr8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032
immune system disease DOID:2914 0 0.026
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012