Danio rerio

0 known processes

tlr8a

toll-like receptor 8a

(Aliases: TIR8.2)

tlr8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.105
positive regulation of transport GO:0051050 2 0.100
nuclear transport GO:0051169 4 0.081
signal transduction GO:0007165 455 0.081
cell surface receptor signaling pathway GO:0007166 325 0.075
regulation of protein localization to nucleus GO:1900180 2 0.071
protein localization to nucleus GO:0034504 3 0.069
maintenance of location GO:0051235 4 0.063
single organism metabolic process GO:0044710 217 0.061
regulation of protein targeting GO:1903533 2 0.055
cellular nitrogen compound metabolic process GO:0034641 290 0.053
regulation of protein import into nucleus GO:0042306 2 0.053
organic cyclic compound metabolic process GO:1901360 301 0.052
aging GO:0007568 2 0.051
regulation of establishment of protein localization GO:0070201 4 0.051
sensory organ development GO:0007423 393 0.049
nucleocytoplasmic transport GO:0006913 4 0.048
cellular macromolecule metabolic process GO:0044260 391 0.048
regulation of signal transduction GO:0009966 225 0.048
protein import GO:0017038 3 0.045
eye development GO:0001654 277 0.045
central nervous system development GO:0007417 387 0.045
nuclear import GO:0051170 3 0.044
regulation of response to stimulus GO:0048583 269 0.044
regulation of protein transport GO:0051223 3 0.044
establishment of protein localization to organelle GO:0072594 4 0.043
small molecule metabolic process GO:0044281 77 0.043
organic substance biosynthetic process GO:1901576 289 0.043
neuron differentiation GO:0030182 353 0.043
protein targeting to nucleus GO:0044744 3 0.043
biosynthetic process GO:0009058 294 0.042
cellular amine metabolic process GO:0044106 2 0.042
regulation of nucleocytoplasmic transport GO:0046822 2 0.041
cellular response to external stimulus GO:0071496 2 0.041
regulation of intracellular protein transport GO:0033157 3 0.040
regulation of cellular metabolic process GO:0031323 320 0.039
multicellular organism growth GO:0035264 4 0.039
gene expression GO:0010467 252 0.039
cognition GO:0050890 1 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
regulation of cytoplasmic transport GO:1903649 4 0.038
cellular component morphogenesis GO:0032989 336 0.038
cellular aromatic compound metabolic process GO:0006725 295 0.038
determination of left right symmetry GO:0007368 179 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.036
heterocycle metabolic process GO:0046483 290 0.036
tube morphogenesis GO:0035239 349 0.036
cell projection organization GO:0030030 284 0.036
camera type eye development GO:0043010 222 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.036
amine metabolic process GO:0009308 2 0.035
single organism transport GO:0044765 206 0.035
regulation of macromolecule metabolic process GO:0060255 317 0.035
morphogenesis of an epithelium GO:0002009 333 0.035
regulation of signaling GO:0023051 235 0.034
cellular biosynthetic process GO:0044249 286 0.033
response to stress GO:0006950 263 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.032
response to organic substance GO:0010033 153 0.032
response to chemical GO:0042221 320 0.032
cellular ketone metabolic process GO:0042180 11 0.031
response to drug GO:0042493 3 0.031
single organism localization GO:1902578 225 0.031
response to alkaloid GO:0043279 2 0.031
regulation of metabolic process GO:0019222 359 0.031
oxoacid metabolic process GO:0043436 31 0.031
locomotion GO:0040011 313 0.030
single organism nuclear import GO:1902593 3 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
determination of bilateral symmetry GO:0009855 204 0.029
transport GO:0006810 220 0.029
protein metabolic process GO:0019538 183 0.029
protein import into nucleus GO:0006606 3 0.029
heart development GO:0007507 313 0.029
retina development in camera type eye GO:0060041 146 0.029
macromolecule biosynthetic process GO:0009059 227 0.029
embryonic organ development GO:0048568 381 0.028
death GO:0016265 121 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
nucleic acid metabolic process GO:0090304 244 0.027
positive regulation of cell cycle GO:0045787 3 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
cellular protein metabolic process GO:0044267 129 0.027
organelle organization GO:0006996 227 0.027
cytoskeleton dependent cytokinesis GO:0061640 3 0.027
rna metabolic process GO:0016070 219 0.027
organic acid metabolic process GO:0006082 31 0.026
regulation of cell communication GO:0010646 232 0.026
generation of neurons GO:0048699 385 0.026
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
mitochondrion organization GO:0007005 4 0.025
cellular component biogenesis GO:0044085 178 0.025
brain development GO:0007420 293 0.025
system process GO:0003008 185 0.025
head development GO:0060322 303 0.025
neuron development GO:0048666 262 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
digestive system development GO:0055123 289 0.024
establishment of localization GO:0051234 244 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
programmed cell death GO:0012501 119 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regionalization GO:0003002 274 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
chordate embryonic development GO:0043009 271 0.023
regulation of primary metabolic process GO:0080090 311 0.023
specification of symmetry GO:0009799 204 0.023
negative regulation of cellular process GO:0048523 283 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
positive regulation of immune effector process GO:0002699 3 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
gtp metabolic process GO:0046039 4 0.022
phagocytosis GO:0006909 3 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
immune system process GO:0002376 241 0.022
erythrocyte homeostasis GO:0034101 55 0.022
regulation of cell activation GO:0050865 1 0.022
rna biosynthetic process GO:0032774 181 0.022
phosphorylation GO:0016310 69 0.022
response to external stimulus GO:0009605 264 0.021
cellular localization GO:0051641 97 0.021
positive regulation of catabolic process GO:0009896 4 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
protein complex localization GO:0031503 1 0.021
regulation of meiotic cell cycle GO:0051445 1 0.021
cell projection morphogenesis GO:0048858 244 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
apoptotic process GO:0006915 116 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
autophagy GO:0006914 4 0.021
multicellular organismal metabolic process GO:0044236 2 0.021
regulation of developmental process GO:0050793 247 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
developmental growth GO:0048589 166 0.020
cell death GO:0008219 121 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
cell part morphogenesis GO:0032990 246 0.020
multi organism process GO:0051704 134 0.020
phosphorus metabolic process GO:0006793 109 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
positive regulation of biological process GO:0048518 253 0.020
eye morphogenesis GO:0048592 144 0.019
lipid storage GO:0019915 1 0.019
gtp catabolic process GO:0006184 2 0.019
lipid catabolic process GO:0016042 4 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
regulation of biosynthetic process GO:0009889 250 0.019
stem cell maintenance GO:0019827 4 0.019
cellular response to nutrient levels GO:0031669 2 0.019
regulation of rna metabolic process GO:0051252 224 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
cellular protein catabolic process GO:0044257 4 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
nucleic acid templated transcription GO:0097659 181 0.018
regulation of reproductive process GO:2000241 4 0.018
cellular component assembly GO:0022607 170 0.018
digestive tract morphogenesis GO:0048546 231 0.018
regulation of metal ion transport GO:0010959 4 0.018
positive regulation of cytokine production GO:0001819 2 0.018
protein secretion GO:0009306 1 0.018
negative regulation of biological process GO:0048519 304 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
digestive tract development GO:0048565 265 0.018
regulation of biological quality GO:0065008 263 0.018
adult behavior GO:0030534 2 0.018
negative regulation of protein transport GO:0051224 3 0.017
neural retina development GO:0003407 49 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
response to monosaccharide GO:0034284 3 0.017
response to nutrient GO:0007584 3 0.017
peptide transport GO:0015833 1 0.017
localization of cell GO:0051674 244 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
rna localization GO:0006403 4 0.017
single organism organelle organization GO:1902589 199 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
growth GO:0040007 174 0.016
meiotic nuclear division GO:0007126 4 0.016
toll like receptor signaling pathway GO:0002224 4 0.016
hindbrain development GO:0030902 91 0.016
cell morphogenesis GO:0000902 289 0.016
negative regulation of signal transduction GO:0009968 94 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
protein modification process GO:0036211 100 0.016
cellular protein modification process GO:0006464 100 0.016
negative regulation of kinase activity GO:0033673 4 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
regulation of protein complex assembly GO:0043254 3 0.016
cellular component movement GO:0006928 335 0.016
regulation of protein catabolic process GO:0042176 1 0.016
vasculature development GO:0001944 278 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
homeostatic process GO:0042592 142 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
antimicrobial humoral response GO:0019730 2 0.015
negative regulation of intracellular protein transport GO:0090317 3 0.015
regulation of gene expression GO:0010468 265 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
striated muscle cell differentiation GO:0051146 129 0.015
transcription dna templated GO:0006351 181 0.015
regulation of inflammatory response GO:0050727 2 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
gland development GO:0048732 143 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
sensory organ morphogenesis GO:0090596 200 0.014
meiotic cell cycle process GO:1903046 3 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
regulation of blood pressure GO:0008217 1 0.014
regulation of transcription dna templated GO:0006355 213 0.014
blood vessel development GO:0001568 246 0.014
hepaticobiliary system development GO:0061008 98 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
regulation of binding GO:0051098 3 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
stem cell proliferation GO:0072089 4 0.014
regulation of cytokine production GO:0001817 3 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
macromolecule modification GO:0043412 111 0.014
positive regulation of secretion GO:0051047 1 0.014
mitotic cytokinesis GO:0000281 3 0.014
neurological system process GO:0050877 62 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
muscle structure development GO:0061061 196 0.014
regulation of tube size GO:0035150 2 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
response to abiotic stimulus GO:0009628 122 0.013
cell motility GO:0048870 244 0.013
regulation of gtpase activity GO:0043087 2 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
cellular amide metabolic process GO:0043603 4 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
response to carbohydrate GO:0009743 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
positive regulation of cellular process GO:0048522 201 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
response to endogenous stimulus GO:0009719 83 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
hemopoiesis GO:0030097 183 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
regulation of synapse organization GO:0050807 3 0.013
response to organic cyclic compound GO:0014070 51 0.013
cytokinesis GO:0000910 3 0.013
tissue remodeling GO:0048771 4 0.013
response to hormone GO:0009725 48 0.012
organelle assembly GO:0070925 110 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
response to hexose GO:0009746 3 0.012
cell substrate adhesion GO:0031589 4 0.012
cellular response to starvation GO:0009267 1 0.012
cell proliferation GO:0008283 80 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
muscle cell differentiation GO:0042692 139 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
compound eye development GO:0048749 2 0.012
regulation of apoptotic process GO:0042981 98 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of circadian rhythm GO:0042752 4 0.012
cell migration GO:0016477 237 0.012
negative regulation of signaling GO:0023057 96 0.012
response to biotic stimulus GO:0009607 97 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
heart looping GO:0001947 94 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
protein phosphorylation GO:0006468 47 0.012
single organism membrane fusion GO:0044801 2 0.012
cellular response to oxygen levels GO:0071453 1 0.012
axonogenesis GO:0007409 152 0.012
response to ketone GO:1901654 1 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
striated muscle cell development GO:0055002 108 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
cellular response to stress GO:0033554 62 0.011
chemosensory behavior GO:0007635 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
germ line stem cell maintenance GO:0030718 2 0.011
regulation of blood vessel size GO:0050880 2 0.011
neuron projection morphogenesis GO:0048812 161 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
protein localization to plasma membrane GO:0072659 1 0.011
protein homooligomerization GO:0051260 3 0.011
macromolecule localization GO:0033036 54 0.011
single organism cellular localization GO:1902580 46 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
type i interferon production GO:0032606 2 0.011
adherens junction organization GO:0034332 4 0.011
b cell activation GO:0042113 2 0.011
lateral line system development GO:0048925 76 0.011
camera type eye morphogenesis GO:0048593 108 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
fertilization GO:0009566 3 0.011
regulation of cell death GO:0010941 103 0.011
intracellular signal transduction GO:0035556 85 0.011
cellular lipid metabolic process GO:0044255 36 0.011
response to corticosteroid GO:0031960 1 0.011
establishment of localization in cell GO:0051649 77 0.011
protein acetylation GO:0006473 2 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
membrane fusion GO:0061025 2 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
exocytosis GO:0006887 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
lipid metabolic process GO:0006629 52 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
neurotransmitter transport GO:0006836 2 0.011
epithelial cell differentiation GO:0030855 116 0.011
myeloid cell homeostasis GO:0002262 56 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
erythrocyte differentiation GO:0030218 54 0.010
hormone secretion GO:0046879 2 0.010
angiogenesis GO:0001525 158 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
regulation of cellular component organization GO:0051128 86 0.010
regulation of calcium ion transport GO:0051924 2 0.010
neuroblast proliferation GO:0007405 2 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of protein metabolic process GO:0051246 56 0.010
neuron projection development GO:0031175 180 0.010
regulation of programmed cell death GO:0043067 101 0.010
regulation of transport GO:0051049 45 0.010
response to uv GO:0009411 3 0.010
regulation of localization GO:0032879 104 0.010
gastrulation GO:0007369 208 0.010
skeletal system development GO:0001501 181 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
behavior GO:0007610 74 0.010
negative regulation of cell communication GO:0010648 96 0.010
negative regulation of metabolic process GO:0009892 86 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
endosomal transport GO:0016197 2 0.010
organelle fusion GO:0048284 3 0.010

tlr8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
nervous system disease DOID:863 0 0.024
disease of metabolism DOID:0014667 0 0.018