Danio rerio

0 known processes

eif4a2

eukaryotic translation initiation factor 4A, isoform 2

(Aliases: wu:fd50g11,zgc:63783)

eif4a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound metabolic process GO:0006807 319 0.188
Fly
regulation of primary metabolic process GO:0080090 311 0.185
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.175
Fly
regulation of mrna splicing via spliceosome GO:0048024 3 0.141
Fly
regulation of mrna processing GO:0050684 3 0.139
Fly
cellular respiration GO:0045333 3 0.107
cellular biosynthetic process GO:0044249 286 0.099
regulation of nitrogen compound metabolic process GO:0051171 251 0.096
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.090
Fly
nuclear transport GO:0051169 4 0.077
gene expression GO:0010467 252 0.074
Fly
rna metabolic process GO:0016070 219 0.073
Fly
positive regulation of biological process GO:0048518 253 0.072
heterocycle metabolic process GO:0046483 290 0.071
Fly
regulation of biological quality GO:0065008 263 0.069
Worm
larval development GO:0002164 2 0.068
Worm
regulation of gene expression GO:0010468 265 0.066
Fly
nucleocytoplasmic transport GO:0006913 4 0.064
regionalization GO:0003002 274 0.063
Fly
single organism transport GO:0044765 206 0.063
locomotion GO:0040011 313 0.063
Worm
nucleobase containing compound metabolic process GO:0006139 274 0.062
Fly
heart development GO:0007507 313 0.060
cellular response to external stimulus GO:0071496 2 0.059
biosynthetic process GO:0009058 294 0.059
response to hexose GO:0009746 3 0.057
vasculature development GO:0001944 278 0.057
aging GO:0007568 2 0.056
Worm
organic cyclic compound metabolic process GO:1901360 301 0.053
Fly
cellular macromolecule metabolic process GO:0044260 391 0.052
Fly
response to monosaccharide GO:0034284 3 0.052
cell projection organization GO:0030030 284 0.051
alpha amino acid metabolic process GO:1901605 3 0.051
response to carbohydrate GO:0009743 3 0.051
positive regulation of cellular process GO:0048522 201 0.051
translational initiation GO:0006413 3 0.050
protein metabolic process GO:0019538 183 0.049
mrna metabolic process GO:0016071 20 0.048
Fly
phagocytosis GO:0006909 3 0.048
cellular nitrogen compound metabolic process GO:0034641 290 0.044
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.044
Fly
cell proliferation GO:0008283 80 0.043
negative regulation of biological process GO:0048519 304 0.042
Fly
head development GO:0060322 303 0.041
stem cell proliferation GO:0072089 4 0.040
single organism nuclear import GO:1902593 3 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.039
Fly
multicellular organism growth GO:0035264 4 0.039
regulation of stem cell proliferation GO:0072091 2 0.038
regulation of muscle contraction GO:0006937 3 0.038
regulation of hormone secretion GO:0046883 2 0.036
response to glucose GO:0009749 3 0.036
sensory organ development GO:0007423 393 0.036
positive regulation of transport GO:0051050 2 0.035
regulation of circadian rhythm GO:0042752 4 0.034
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.034
Fly
protein localization to nucleus GO:0034504 3 0.033
endothelial cell fate commitment GO:0060839 3 0.032
carboxylic acid metabolic process GO:0019752 22 0.031
protein import GO:0017038 3 0.031
positive regulation of translation GO:0045727 1 0.031
actin polymerization or depolymerization GO:0008154 2 0.030
response to vitamin GO:0033273 3 0.030
cellular response to nutrient levels GO:0031669 2 0.030
maintenance of location GO:0051235 4 0.030
Worm
regulation of cellular metabolic process GO:0031323 320 0.030
Fly
apoptotic process GO:0006915 116 0.029
protein stabilization GO:0050821 2 0.029
regulation of cell communication GO:0010646 232 0.029
regulation of translational initiation GO:0006446 1 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.029
signal transduction GO:0007165 455 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
Worm
rna localization GO:0006403 4 0.027
generation of neurons GO:0048699 385 0.027
single organism metabolic process GO:0044710 217 0.027
central nervous system development GO:0007417 387 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
somite development GO:0061053 96 0.025
rna export from nucleus GO:0006405 1 0.025
skeletal muscle organ development GO:0060538 78 0.025
mesenchymal cell proliferation GO:0010463 1 0.025
embryonic limb morphogenesis GO:0030326 2 0.025
organic acid metabolic process GO:0006082 31 0.025
negative regulation of protein complex assembly GO:0031333 1 0.024
mrna processing GO:0006397 14 0.024
Fly
regulation of biosynthetic process GO:0009889 250 0.024
muscle structure development GO:0061061 196 0.023
hormone secretion GO:0046879 2 0.023
protein modification process GO:0036211 100 0.023
protein targeting to nucleus GO:0044744 3 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
dorsal ventral pattern formation GO:0009953 125 0.022
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.022
cellular protein metabolic process GO:0044267 129 0.022
cellular component disassembly GO:0022411 1 0.022
regulation of protein ubiquitination GO:0031396 3 0.022
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.022
regulation of protein complex disassembly GO:0043244 1 0.021
negative regulation of cellular catabolic process GO:0031330 3 0.021
regulation of metabolic process GO:0019222 359 0.021
Fly
regulation of rna metabolic process GO:0051252 224 0.021
Fly
cellular response to extracellular stimulus GO:0031668 2 0.021
regulation of apoptotic process GO:0042981 98 0.021
peptide transport GO:0015833 1 0.021
hormone transport GO:0009914 2 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.020
carboxylic acid catabolic process GO:0046395 3 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
macromolecule modification GO:0043412 111 0.020
mechanosensory lateral line system development GO:0048881 49 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
cellular amino acid biosynthetic process GO:0008652 2 0.020
chordate embryonic development GO:0043009 271 0.020
response to chemical GO:0042221 320 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
organic substance biosynthetic process GO:1901576 289 0.019
regulation of cell activation GO:0050865 1 0.019
regulation of stem cell differentiation GO:2000736 4 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of developmental process GO:0050793 247 0.019
Fly
lipid storage GO:0019915 1 0.019
Worm
sensory perception of pain GO:0019233 1 0.019
cellular modified amino acid metabolic process GO:0006575 3 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
positive regulation of cell cycle GO:0045787 3 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
nuclear import GO:0051170 3 0.018
ribosomal small subunit biogenesis GO:0042274 2 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
nuclear export GO:0051168 1 0.018
embryonic organ development GO:0048568 381 0.018
nitrogen compound transport GO:0071705 23 0.018
regulation of binding GO:0051098 3 0.018
phosphorus metabolic process GO:0006793 109 0.017
startle response GO:0001964 4 0.017
negative regulation of signal transduction GO:0009968 94 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
negative regulation of catabolic process GO:0009895 3 0.017
immune system process GO:0002376 241 0.017
intracellular estrogen receptor signaling pathway GO:0030520 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
protein polymerization GO:0051258 4 0.016
regulation of transcription dna templated GO:0006355 213 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.016
Fly
establishment of rna localization GO:0051236 3 0.016
segmentation GO:0035282 97 0.016
transmembrane transport GO:0055085 120 0.016
regulation of transporter activity GO:0032409 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
protein import into nucleus GO:0006606 3 0.016
establishment of localization GO:0051234 244 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
organonitrogen compound biosynthetic process GO:1901566 47 0.016
response to stress GO:0006950 263 0.015
Fly
macromolecule biosynthetic process GO:0009059 227 0.015
transport GO:0006810 220 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
spliceosomal complex assembly GO:0000245 1 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
oxoacid metabolic process GO:0043436 31 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
regulation of dna replication GO:0006275 3 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
growth GO:0040007 174 0.015
dicarboxylic acid metabolic process GO:0043648 1 0.015
endocardial cushion formation GO:0003272 2 0.015
regulation of metal ion transport GO:0010959 4 0.014
response to nutrient GO:0007584 3 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
ear morphogenesis GO:0042471 64 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
positive regulation of cell death GO:0010942 29 0.014
positive regulation of cytokine production GO:0001819 2 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
gtp metabolic process GO:0046039 4 0.014
positive regulation of gene expression GO:0010628 71 0.014
regulation of cell differentiation GO:0045595 142 0.014
Fly
regulation of reproductive process GO:2000241 4 0.014
midbrain development GO:0030901 28 0.014
actin filament polymerization GO:0030041 2 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
meiotic nuclear division GO:0007126 4 0.014
muscle tissue development GO:0060537 110 0.014
organelle organization GO:0006996 227 0.014
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
rna processing GO:0006396 25 0.014
Fly
mesenchyme development GO:0060485 127 0.014
response to external biotic stimulus GO:0043207 97 0.014
negative regulation of rna splicing GO:0033119 1 0.014
rna biosynthetic process GO:0032774 181 0.014
lateral line development GO:0048882 66 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of organ growth GO:0046620 3 0.013
nucleic acid templated transcription GO:0097659 181 0.013
sensory organ morphogenesis GO:0090596 200 0.013
amine metabolic process GO:0009308 2 0.013
specification of symmetry GO:0009799 204 0.013
response to external stimulus GO:0009605 264 0.013
muscle organ development GO:0007517 101 0.013
regulation of rna splicing GO:0043484 8 0.013
Fly
nephron tubule morphogenesis GO:0072078 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
nucleic acid transport GO:0050657 2 0.013
stem cell maintenance GO:0019827 4 0.013
Fly
rna transport GO:0050658 2 0.013
response to amino acid GO:0043200 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.012
hemopoiesis GO:0030097 183 0.012
cellular component biogenesis GO:0044085 178 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
transcription dna templated GO:0006351 181 0.012
system process GO:0003008 185 0.012
atp catabolic process GO:0006200 4 0.012
microtubule organizing center organization GO:0031023 1 0.012
Fly
cellular component morphogenesis GO:0032989 336 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
nucleic acid metabolic process GO:0090304 244 0.012
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
urogenital system development GO:0001655 97 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of ion transmembrane transport GO:0034765 18 0.012
cellular nitrogen compound catabolic process GO:0044270 15 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
ear development GO:0043583 127 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
regulation of protein depolymerization GO:1901879 1 0.012
inorganic cation transmembrane transport GO:0098662 50 0.012
regulation of response to stimulus GO:0048583 269 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
regulation of cell proliferation GO:0042127 37 0.012
cognition GO:0050890 1 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
cellular localization GO:0051641 97 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
cellular protein modification process GO:0006464 100 0.011
macromolecular complex assembly GO:0065003 35 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
lymphatic endothelial cell differentiation GO:0060836 1 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
Fly
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.011
immune system development GO:0002520 191 0.011
cell cycle GO:0007049 93 0.011
Fly
posttranscriptional regulation of gene expression GO:0010608 14 0.011
cell part morphogenesis GO:0032990 246 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
glucose homeostasis GO:0042593 1 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of myotube differentiation GO:0010830 2 0.011
carbohydrate homeostasis GO:0033500 1 0.011
regulation of signaling GO:0023051 235 0.011
cell activation GO:0001775 16 0.011
neuron projection morphogenesis GO:0048812 161 0.011
positive regulation of secretion GO:0051047 1 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
ribonucleoprotein complex assembly GO:0022618 5 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
myotube differentiation GO:0014902 45 0.011
exocrine pancreas development GO:0031017 28 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
aorta development GO:0035904 4 0.011
protein dephosphorylation GO:0006470 3 0.011
regulation of protein binding GO:0043393 3 0.011
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
cell aging GO:0007569 2 0.011
response to endogenous stimulus GO:0009719 83 0.011
oocyte maturation GO:0001556 4 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
entrainment of circadian clock GO:0009649 2 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
entrainment of circadian clock by photoperiod GO:0043153 1 0.010
sensory system development GO:0048880 76 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
negative regulation of gene expression GO:0010629 65 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
cellular response to starvation GO:0009267 1 0.010
striated muscle tissue development GO:0014706 110 0.010
small molecule metabolic process GO:0044281 77 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
neuroblast proliferation GO:0007405 2 0.010
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
cellular protein complex disassembly GO:0043624 1 0.010
cell morphogenesis GO:0000902 289 0.010
gtp catabolic process GO:0006184 2 0.010

eif4a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
disease of metabolism DOID:0014667 0 0.014
cardiovascular system disease DOID:1287 0 0.014
disease of cellular proliferation DOID:14566 0 0.011
nervous system disease DOID:863 0 0.010