Danio rerio

0 known processes

dpysl4

dihydropyrimidinase-like 4

(Aliases: CRMP-3)

dpysl4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 353 0.445
Zebrafish
neuron projection regeneration GO:0031102 16 0.261
Zebrafish
establishment of localization GO:0051234 244 0.205
larval development GO:0002164 2 0.148
ion transport GO:0006811 114 0.135
peripheral nervous system neuron axonogenesis GO:0048936 13 0.129
Zebrafish
generation of neurons GO:0048699 385 0.128
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.110
cation transmembrane transport GO:0098655 65 0.104
single organism localization GO:1902578 225 0.103
regeneration GO:0031099 91 0.097
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.092
ion transmembrane transport GO:0034220 91 0.089
cognition GO:0050890 1 0.077
response to stress GO:0006950 263 0.076
Zebrafish
response to axon injury GO:0048678 14 0.073
Zebrafish
regulation of neuron migration GO:2001222 2 0.072
embryonic skeletal system development GO:0048706 97 0.069
single organism transport GO:0044765 206 0.068
camera type eye development GO:0043010 222 0.066
digestive tract development GO:0048565 265 0.065
regulation of cellular biosynthetic process GO:0031326 245 0.059
transport GO:0006810 220 0.057
regulation of postsynaptic membrane potential GO:0060078 1 0.057
gene expression GO:0010467 252 0.055
regulation of protein complex assembly GO:0043254 3 0.054
neuron development GO:0048666 262 0.052
Zebrafish
golgi vesicle transport GO:0048193 3 0.050
embryonic organ development GO:0048568 381 0.047
cell part morphogenesis GO:0032990 246 0.046
Zebrafish
regulation of gene expression GO:0010468 265 0.046
protein localization to plasma membrane GO:0072659 1 0.045
skeletal system development GO:0001501 181 0.045
regulation of signaling GO:0023051 235 0.045
regulation of ion transmembrane transporter activity GO:0032412 2 0.044
regulation of synapse assembly GO:0051963 3 0.044
multicellular organism growth GO:0035264 4 0.042
response to wounding GO:0009611 116 0.042
Zebrafish
organic acid metabolic process GO:0006082 31 0.042
regulation of ion transmembrane transport GO:0034765 18 0.041
tube morphogenesis GO:0035239 349 0.040
regulation of binding GO:0051098 3 0.040
regulation of calcium ion transport GO:0051924 2 0.039
protein complex assembly GO:0006461 30 0.039
locomotory behavior GO:0007626 34 0.038
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.038
synaptic growth at neuromuscular junction GO:0051124 2 0.037
signal transduction GO:0007165 455 0.037
transmembrane transport GO:0055085 120 0.036
protein secretion GO:0009306 1 0.036
leukocyte proliferation GO:0070661 1 0.035
neuron projection development GO:0031175 180 0.035
Zebrafish
oxoacid metabolic process GO:0043436 31 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
membrane organization GO:0061024 21 0.034
neuromuscular process controlling balance GO:0050885 3 0.034
positive regulation of cellular process GO:0048522 201 0.033
locomotion GO:0040011 313 0.033
synaptic vesicle recycling GO:0036465 1 0.033
post golgi vesicle mediated transport GO:0006892 1 0.033
gastrulation GO:0007369 208 0.033
anatomical structure arrangement GO:0048532 2 0.033
digestive tract morphogenesis GO:0048546 231 0.032
peptide transport GO:0015833 1 0.032
synaptic vesicle transport GO:0048489 1 0.032
digestive system development GO:0055123 289 0.032
neurological system process GO:0050877 62 0.032
sensory perception of pain GO:0019233 1 0.031
regulation of mrna processing GO:0050684 3 0.031
cranial nerve development GO:0021545 42 0.030
actin polymerization or depolymerization GO:0008154 2 0.030
regulation of synaptic plasticity GO:0048167 1 0.030
synaptic vesicle endocytosis GO:0048488 1 0.029
exocytosis GO:0006887 1 0.029
membrane invagination GO:0010324 1 0.029
cell projection organization GO:0030030 284 0.029
Zebrafish
nephron epithelium morphogenesis GO:0072088 1 0.029
adult behavior GO:0030534 2 0.029
behavior GO:0007610 74 0.028
synaptic vesicle localization GO:0097479 1 0.028
chordate embryonic development GO:0043009 271 0.028
axon development GO:0061564 166 0.028
Zebrafish
cellular response to stress GO:0033554 62 0.027
Zebrafish
regulation of metabolic process GO:0019222 359 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.026
cellular amine metabolic process GO:0044106 2 0.026
inorganic cation transmembrane transport GO:0098662 50 0.026
calcium ion transmembrane transport GO:0070588 13 0.026
amine metabolic process GO:0009308 2 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
regulation of protein binding GO:0043393 3 0.025
cellular biosynthetic process GO:0044249 286 0.025
protein localization to membrane GO:0072657 9 0.025
protein complex biogenesis GO:0070271 30 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
cation transport GO:0006812 81 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.024
sensory perception GO:0007600 39 0.024
growth GO:0040007 174 0.024
smooth muscle contraction GO:0006939 2 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
positive regulation of transport GO:0051050 2 0.023
regulation of transmembrane transporter activity GO:0022898 2 0.023
aging GO:0007568 2 0.023
neurotransmitter transport GO:0006836 2 0.023
regulation of developmental process GO:0050793 247 0.023
protein heterooligomerization GO:0051291 1 0.022
directional locomotion GO:0033058 1 0.022
cellular component maintenance GO:0043954 3 0.022
macromolecular complex disassembly GO:0032984 1 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
peripheral nervous system neuron development GO:0048935 22 0.021
Zebrafish
cellular amino acid metabolic process GO:0006520 7 0.021
regulation of synapse organization GO:0050807 3 0.021
collateral sprouting in absence of injury GO:0048669 4 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
regulation of metal ion transport GO:0010959 4 0.021
inorganic ion transmembrane transport GO:0098660 57 0.020
cellular component assembly GO:0022607 170 0.020
regulation of cellular component organization GO:0051128 86 0.020
mononuclear cell proliferation GO:0032943 1 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
maternal determination of anterior posterior axis embryo GO:0008358 4 0.020
glutamate receptor signaling pathway GO:0007215 1 0.020
biosynthetic process GO:0009058 294 0.020
rna metabolic process GO:0016070 219 0.020
neural tube development GO:0021915 62 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
heterocycle metabolic process GO:0046483 290 0.020
organic substance biosynthetic process GO:1901576 289 0.019
cellular amide metabolic process GO:0043603 4 0.019
dorsal spinal cord development GO:0021516 1 0.019
system process GO:0003008 185 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
Zebrafish
regulation of dendrite development GO:0050773 3 0.019
primary neural tube formation GO:0014020 1 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
enteric nervous system development GO:0048484 12 0.019
microtubule based movement GO:0007018 33 0.018
endosomal transport GO:0016197 2 0.018
axon regeneration GO:0031103 14 0.018
Zebrafish
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.018
regulation of biological quality GO:0065008 263 0.018
myelination GO:0042552 18 0.018
regulation of reproductive process GO:2000241 4 0.018
negative regulation of metabolic process GO:0009892 86 0.018
female sex differentiation GO:0046660 4 0.018
neuron projection morphogenesis GO:0048812 161 0.018
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.018
regulation of transmembrane transport GO:0034762 18 0.018
rna biosynthetic process GO:0032774 181 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
embryonic skeletal system morphogenesis GO:0048704 93 0.017
small molecule metabolic process GO:0044281 77 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
response to chemical GO:0042221 320 0.017
cellular component morphogenesis GO:0032989 336 0.017
Zebrafish
regulation of cell communication GO:0010646 232 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
microtubule based process GO:0007017 60 0.017
vestibular reflex GO:0060005 2 0.017
regulation of receptor activity GO:0010469 2 0.017
protein metabolic process GO:0019538 183 0.017
developmental programmed cell death GO:0010623 4 0.017
voltage gated calcium channel complex assembly GO:0070978 1 0.016
rostrocaudal neural tube patterning GO:0021903 29 0.016
establishment of melanosome localization GO:0032401 19 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
neurotransmitter secretion GO:0007269 2 0.016
regionalization GO:0003002 274 0.016
sympathetic nervous system development GO:0048485 3 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
determination of bilateral symmetry GO:0009855 204 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
positive regulation of leukocyte differentiation GO:1902107 1 0.016
negative regulation of cellular process GO:0048523 283 0.015
peripheral nervous system neuron differentiation GO:0048934 28 0.015
Zebrafish
transmission of nerve impulse GO:0019226 19 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
nephron tubule morphogenesis GO:0072078 1 0.015
positive regulation of biological process GO:0048518 253 0.015
nuclear import GO:0051170 3 0.015
transcription dna templated GO:0006351 181 0.015
morphogenesis of an epithelial sheet GO:0002011 49 0.015
response to abiotic stimulus GO:0009628 122 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
regulation of cell activation GO:0050865 1 0.014
regulation of cell differentiation GO:0045595 142 0.014
melanosome transport GO:0032402 19 0.014
negative regulation of reproductive process GO:2000242 3 0.014
amino acid transport GO:0006865 2 0.014
melanin metabolic process GO:0006582 2 0.014
cellular protein metabolic process GO:0044267 129 0.014
protein depolymerization GO:0051261 1 0.014
response to hydrogen peroxide GO:0042542 3 0.014
phagocytosis GO:0006909 3 0.014
cellular component disassembly GO:0022411 1 0.014
lymphocyte proliferation GO:0046651 1 0.014
collateral sprouting GO:0048668 9 0.014
regulation of transporter activity GO:0032409 2 0.014
secondary metabolic process GO:0019748 3 0.014
regulation of synapse structure and activity GO:0050803 5 0.014
embryonic skeletal joint morphogenesis GO:0060272 3 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
mitochondrion organization GO:0007005 4 0.013
gtp catabolic process GO:0006184 2 0.013
embryonic skeletal joint development GO:0072498 3 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
female gonad development GO:0008585 4 0.013
meiotic nuclear division GO:0007126 4 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.013
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.013
regulation of neuron differentiation GO:0045664 56 0.013
pronephros development GO:0048793 69 0.013
metal ion transport GO:0030001 58 0.013
regulation of protein metabolic process GO:0051246 56 0.013
autophagy GO:0006914 4 0.013
regulation of protein transport GO:0051223 3 0.013
protein stabilization GO:0050821 2 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
cellular ketone metabolic process GO:0042180 11 0.013
striated muscle contraction GO:0006941 12 0.013
nephron morphogenesis GO:0072028 2 0.013
hormone secretion GO:0046879 2 0.013
regulation of neuron projection development GO:0010975 40 0.013
regulation of membrane potential GO:0042391 23 0.013
protein homooligomerization GO:0051260 3 0.013
single organism membrane organization GO:0044802 20 0.013
positive regulation of glucose import GO:0046326 1 0.013
chemosensory behavior GO:0007635 1 0.013
gtp metabolic process GO:0046039 4 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
axon cargo transport GO:0008088 2 0.013
membrane hyperpolarization GO:0060081 1 0.013
organelle organization GO:0006996 227 0.013
positive regulation of protein complex assembly GO:0031334 2 0.012
locomotor rhythm GO:0045475 3 0.012
multi organism process GO:0051704 134 0.012
determination of left right symmetry GO:0007368 179 0.012
axonogenesis GO:0007409 152 0.012
Zebrafish
regulation of dendrite morphogenesis GO:0048814 3 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
locus ceruleus development GO:0021703 3 0.012
notochord cell differentiation GO:0060034 18 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
facial nerve morphogenesis GO:0021610 1 0.012
long chain fatty acid biosynthetic process GO:0042759 1 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
peptidyl threonine modification GO:0018210 1 0.012
protein modification process GO:0036211 100 0.012
regulation of jak stat cascade GO:0046425 3 0.012
receptor internalization GO:0031623 2 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
positive regulation of multi organism process GO:0043902 3 0.012
peptidyl serine modification GO:0018209 2 0.012
cell morphogenesis GO:0000902 289 0.012
Zebrafish
establishment of vesicle localization GO:0051650 24 0.011
phagocytosis engulfment GO:0006911 1 0.011
establishment of pigment granule localization GO:0051905 22 0.011
midbrain development GO:0030901 28 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
adherens junction organization GO:0034332 4 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
nerve development GO:0021675 45 0.011
multicellular organismal signaling GO:0035637 22 0.011
negative regulation of biological process GO:0048519 304 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
regulation of calcium mediated signaling GO:0050848 1 0.011
gabaergic neuron differentiation GO:0097154 2 0.011
pole plasm assembly GO:0007315 4 0.011
spinal cord association neuron differentiation GO:0021527 1 0.011
fatty acid biosynthetic process GO:0006633 4 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
spinal cord development GO:0021510 46 0.011
regulation of glucose import GO:0046324 1 0.011
trigeminal nerve development GO:0021559 3 0.011
response to glucocorticoid GO:0051384 1 0.011
cellular component biogenesis GO:0044085 178 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
protein polymerization GO:0051258 4 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.010
macromolecule localization GO:0033036 54 0.010
single organism cellular localization GO:1902580 46 0.010
inner ear receptor cell fate commitment GO:0060120 4 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
spermatid development GO:0007286 2 0.010
positive regulation of cell activation GO:0050867 1 0.010
actin filament polymerization GO:0030041 2 0.010
sensory organ morphogenesis GO:0090596 200 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
heart development GO:0007507 313 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
positive regulation of metabolic process GO:0009893 108 0.010
regulation of synaptic vesicle transport GO:1902803 1 0.010
regulation of photoreceptor cell differentiation GO:0046532 2 0.010
nuclear migration GO:0007097 3 0.010
regulation of rna metabolic process GO:0051252 224 0.010

dpysl4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.076
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.010