Danio rerio

0 known processes

chp2

calcineurin B homologous protein 2

(Aliases: zgc:55363,wu:fi19e07)

chp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.062
cellular ketone metabolic process GO:0042180 11 0.062
cellular macromolecule metabolic process GO:0044260 391 0.059
amine metabolic process GO:0009308 2 0.058
regulation of mrna processing GO:0050684 3 0.055
organic cyclic compound metabolic process GO:1901360 301 0.055
establishment of protein localization to organelle GO:0072594 4 0.054
aging GO:0007568 2 0.051
maintenance of location GO:0051235 4 0.047
protein localization to plasma membrane GO:0072659 1 0.047
cellular amine metabolic process GO:0044106 2 0.047
regulation of cellular amine metabolic process GO:0033238 0 0.046
stem cell proliferation GO:0072089 4 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.046
response to stress GO:0006950 263 0.043
regulation of gene expression GO:0010468 265 0.043
central nervous system development GO:0007417 387 0.043
regulation of cellular amino acid metabolic process GO:0006521 0 0.043
cellular protein catabolic process GO:0044257 4 0.041
modification dependent protein catabolic process GO:0019941 3 0.041
protein metabolic process GO:0019538 183 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.040
immune system process GO:0002376 241 0.040
regulation of rna metabolic process GO:0051252 224 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
regulation of primary metabolic process GO:0080090 311 0.038
proteasomal protein catabolic process GO:0010498 2 0.038
regulation of protein catabolic process GO:0042176 1 0.037
regulation of biological quality GO:0065008 263 0.037
ubiquitin dependent protein catabolic process GO:0006511 3 0.036
brain development GO:0007420 293 0.035
regulation of developmental process GO:0050793 247 0.035
protein localization to nucleus GO:0034504 3 0.035
lipid storage GO:0019915 1 0.034
hemopoiesis GO:0030097 183 0.034
regulation of cellular metabolic process GO:0031323 320 0.034
negative regulation of protein phosphorylation GO:0001933 4 0.034
regulation of cellular ketone metabolic process GO:0010565 7 0.034
nitrogen compound metabolic process GO:0006807 319 0.033
single organism organelle organization GO:1902589 199 0.033
positive regulation of histone modification GO:0031058 1 0.032
regulation of cellular biosynthetic process GO:0031326 245 0.032
regulation of glucose transport GO:0010827 1 0.032
rna biosynthetic process GO:0032774 181 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
rna metabolic process GO:0016070 219 0.031
regulation of metabolic process GO:0019222 359 0.030
regulation of response to stimulus GO:0048583 269 0.030
negative regulation of cellular process GO:0048523 283 0.030
carboxylic acid metabolic process GO:0019752 22 0.030
negative regulation of biological process GO:0048519 304 0.029
regulation of glucose import GO:0046324 1 0.029
nucleic acid metabolic process GO:0090304 244 0.029
regulation of macromolecule metabolic process GO:0060255 317 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
response to drug GO:0042493 3 0.028
oxoacid metabolic process GO:0043436 31 0.028
protein acetylation GO:0006473 2 0.028
transcription dna templated GO:0006351 181 0.027
single organism localization GO:1902578 225 0.027
larval development GO:0002164 2 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
leukocyte proliferation GO:0070661 1 0.027
peptidyl threonine phosphorylation GO:0018107 1 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
regulation of protein ubiquitination GO:0031396 3 0.026
response to monosaccharide GO:0034284 3 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.026
regulation of biosynthetic process GO:0009889 250 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
positive regulation of transport GO:0051050 2 0.026
organic acid metabolic process GO:0006082 31 0.026
chromatin modification GO:0016568 21 0.026
head development GO:0060322 303 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
protein dephosphorylation GO:0006470 3 0.025
nuclear transport GO:0051169 4 0.025
organelle organization GO:0006996 227 0.025
positive regulation of map kinase activity GO:0043406 3 0.025
response to chemical GO:0042221 320 0.024
nucleic acid templated transcription GO:0097659 181 0.024
negative regulation of catabolic process GO:0009895 3 0.024
peptidyl lysine acetylation GO:0018394 2 0.024
single organism transport GO:0044765 206 0.024
cellular response to starvation GO:0009267 1 0.024
tube morphogenesis GO:0035239 349 0.023
mononuclear cell proliferation GO:0032943 1 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
regulation of stem cell proliferation GO:0072091 2 0.023
positive regulation of catabolic process GO:0009896 4 0.023
single organism metabolic process GO:0044710 217 0.023
cell cycle GO:0007049 93 0.023
response to hexose GO:0009746 3 0.023
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.023
cellular response to nutrient levels GO:0031669 2 0.022
regulation of cellular protein catabolic process GO:1903362 1 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
biosynthetic process GO:0009058 294 0.022
heterocycle metabolic process GO:0046483 290 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
system process GO:0003008 185 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
stem cell division GO:0017145 1 0.022
cell proliferation GO:0008283 80 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
regulation of protein complex assembly GO:0043254 3 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.021
gene expression GO:0010467 252 0.021
glucose import GO:0046323 2 0.021
cellular biosynthetic process GO:0044249 286 0.021
regulation of reactive oxygen species metabolic process GO:2000377 2 0.021
nuclear migration GO:0007097 3 0.021
regulation of protein transport GO:0051223 3 0.021
regulation of cell activation GO:0050865 1 0.021
negative regulation of gene expression GO:0010629 65 0.021
oocyte maturation GO:0001556 4 0.021
regulation of cell communication GO:0010646 232 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
b cell activation GO:0042113 2 0.021
membrane lipid biosynthetic process GO:0046467 2 0.021
cortical cytoskeleton organization GO:0030865 1 0.021
regulation of signal transduction GO:0009966 225 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
multicellular organism growth GO:0035264 4 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
stem cell maintenance GO:0019827 4 0.020
cellular response to external stimulus GO:0071496 2 0.020
response to organic substance GO:0010033 153 0.020
response to carbohydrate GO:0009743 3 0.020
autophagy GO:0006914 4 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
regulation of localization GO:0032879 104 0.020
response to abiotic stimulus GO:0009628 122 0.020
macromolecule modification GO:0043412 111 0.020
macromolecule biosynthetic process GO:0009059 227 0.019
generation of neurons GO:0048699 385 0.019
signal transduction GO:0007165 455 0.019
protein targeting to membrane GO:0006612 1 0.019
cellular protein metabolic process GO:0044267 129 0.019
regulation of binding GO:0051098 3 0.019
hormone transport GO:0009914 2 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
protein polymerization GO:0051258 4 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
gtp metabolic process GO:0046039 4 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
protein acylation GO:0043543 3 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.019
germ line stem cell maintenance GO:0030718 2 0.019
protein import into nucleus GO:0006606 3 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
endosomal transport GO:0016197 2 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
negative regulation of protein complex assembly GO:0031333 1 0.018
small molecule metabolic process GO:0044281 77 0.018
cellular response to organic substance GO:0071310 105 0.018
immune system development GO:0002520 191 0.018
positive regulation of chromosome organization GO:2001252 1 0.018
positive regulation of cell cycle GO:0045787 3 0.017
protein import GO:0017038 3 0.017
neuroblast proliferation GO:0007405 2 0.017
medulla oblongata development GO:0021550 4 0.017
homeostatic process GO:0042592 142 0.017
golgi vesicle transport GO:0048193 3 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
cytoskeleton organization GO:0007010 96 0.017
organelle fusion GO:0048284 3 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
regulation of signaling GO:0023051 235 0.017
actin filament polymerization GO:0030041 2 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
centrosome organization GO:0051297 1 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
response to uv GO:0009411 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
regulation of blood pressure GO:0008217 1 0.017
organic substance biosynthetic process GO:1901576 289 0.017
cell aging GO:0007569 2 0.017
cellular component assembly GO:0022607 170 0.017
establishment of localization GO:0051234 244 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
phagocytosis GO:0006909 3 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
protein stabilization GO:0050821 2 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
response to glucose GO:0009749 3 0.016
activation of mapk activity GO:0000187 3 0.016
muscle structure development GO:0061061 196 0.016
cell morphogenesis GO:0000902 289 0.016
hormone secretion GO:0046879 2 0.016
heart development GO:0007507 313 0.016
response to vitamin GO:0033273 3 0.016
spermatid differentiation GO:0048515 2 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
nuclear import GO:0051170 3 0.016
meiotic cell cycle process GO:1903046 3 0.016
sensory organ morphogenesis GO:0090596 200 0.016
cell migration GO:0016477 237 0.016
peptidyl threonine modification GO:0018210 1 0.016
positive regulation of lipid metabolic process GO:0045834 1 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
cellular amide metabolic process GO:0043603 4 0.016
single organism nuclear import GO:1902593 3 0.015
regulation of reproductive process GO:2000241 4 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
embryonic organ development GO:0048568 381 0.015
retina development in camera type eye GO:0060041 146 0.015
nuclear export GO:0051168 1 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
cellular component movement GO:0006928 335 0.015
microtubule organizing center organization GO:0031023 1 0.015
cortical actin cytoskeleton organization GO:0030866 1 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
lymphocyte proliferation GO:0046651 1 0.015
eye development GO:0001654 277 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
double strand break repair GO:0006302 3 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
myeloid cell differentiation GO:0030099 86 0.014
response to external stimulus GO:0009605 264 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
regulation of transcription dna templated GO:0006355 213 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
regulation of cell differentiation GO:0045595 142 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of hormone secretion GO:0046883 2 0.014
protein targeting to nucleus GO:0044744 3 0.014
mitotic cytokinesis GO:0000281 3 0.014
regulation of cell shape GO:0008360 1 0.014
apoptotic process GO:0006915 116 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
regulation of jak stat cascade GO:0046425 3 0.014
cellular localization GO:0051641 97 0.014
adult behavior GO:0030534 2 0.014
positive regulation of blood circulation GO:1903524 2 0.014
response to amino acid GO:0043200 2 0.014
negative regulation of rna biosynthetic process GO:1902679 45 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
regulation of inflammatory response GO:0050727 2 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
membrane fusion GO:0061025 2 0.013
lipid catabolic process GO:0016042 4 0.013
adherens junction organization GO:0034332 4 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
positive regulation of glucose transport GO:0010828 1 0.013
sleep GO:0030431 1 0.013
b cell differentiation GO:0030183 1 0.013
regulation of protein targeting GO:1903533 2 0.013
establishment of localization in cell GO:0051649 77 0.013
primary neural tube formation GO:0014020 1 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
negative regulation of nucleic acid templated transcription GO:1903507 45 0.013
erythrocyte development GO:0048821 24 0.013
heart looping GO:0001947 94 0.013
response to hydrogen peroxide GO:0042542 3 0.013
regulation of filopodium assembly GO:0051489 2 0.013
regulation of cell cycle process GO:0010564 20 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
positive regulation of cell activation GO:0050867 1 0.012
regulation of cell cycle GO:0051726 52 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
regulation of wound healing GO:0061041 2 0.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
ameboidal type cell migration GO:0001667 143 0.012
positive regulation of glucose import GO:0046326 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
programmed cell death GO:0012501 119 0.012
response to wounding GO:0009611 116 0.012
telomere maintenance GO:0000723 1 0.012
regulation of cytokine production GO:0001817 3 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
alcohol biosynthetic process GO:0046165 2 0.012
determination of left right symmetry GO:0007368 179 0.012
negative regulation of cell communication GO:0010648 96 0.012
mesodermal cell migration GO:0008078 12 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
cell motility GO:0048870 244 0.012
regulation of blood coagulation GO:0030193 1 0.012
telomere organization GO:0032200 1 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
secondary metabolic process GO:0019748 3 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
gtp catabolic process GO:0006184 2 0.012
regulation of lipid transport GO:0032368 4 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
regulation of transporter activity GO:0032409 2 0.012
glucose homeostasis GO:0042593 1 0.012
female sex differentiation GO:0046660 4 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
specification of symmetry GO:0009799 204 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
female meiotic division GO:0007143 2 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
actin filament based process GO:0030029 64 0.011
monoamine transport GO:0015844 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
negative regulation of defense response GO:0031348 2 0.011
nitric oxide metabolic process GO:0046209 2 0.011
regulation of organelle assembly GO:1902115 4 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
sequestering of calcium ion GO:0051208 3 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
transport GO:0006810 220 0.011
response to nutrient GO:0007584 3 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
cytokinesis GO:0000910 3 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
cell cycle arrest GO:0007050 1 0.011
cellular respiration GO:0045333 3 0.011
cell projection assembly GO:0030031 64 0.011
positive regulation of translation GO:0045727 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
superoxide metabolic process GO:0006801 2 0.011
cellular lipid metabolic process GO:0044255 36 0.011
digestive tract morphogenesis GO:0048546 231 0.011
organelle assembly GO:0070925 110 0.011
regulation of cell projection assembly GO:0060491 4 0.011
negative chemotaxis GO:0050919 1 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
regulation of protein polymerization GO:0032271 2 0.011
homeostasis of number of cells GO:0048872 62 0.011
protein modification process GO:0036211 100 0.011
vasculature development GO:0001944 278 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
b cell mediated immunity GO:0019724 3 0.011
rna localization GO:0006403 4 0.011
ceramide metabolic process GO:0006672 5 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
regulation of jun kinase activity GO:0043506 3 0.011
histone phosphorylation GO:0016572 2 0.011
amino acid transport GO:0006865 2 0.011
glycolipid biosynthetic process GO:0009247 1 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
regulation of dendrite development GO:0050773 3 0.010
establishment or maintenance of cell polarity GO:0007163 29 0.010
organelle localization GO:0051640 49 0.010
synaptic target recognition GO:0008039 1 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.010
mitotic cell cycle GO:0000278 64 0.010
smooth muscle contraction GO:0006939 2 0.010
female gonad development GO:0008585 4 0.010
regulation of tube size GO:0035150 2 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
endocrine hormone secretion GO:0060986 2 0.010
circadian sleep wake cycle GO:0042745 2 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
positive regulation of cytokine production GO:0001819 2 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
determination of bilateral symmetry GO:0009855 204 0.010
mrna 3 end processing GO:0031124 2 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
negative regulation of nuclear division GO:0051784 3 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.010
cellular response to dna damage stimulus GO:0006974 24 0.010
response to corticosteroid GO:0031960 1 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
regulation of muscle contraction GO:0006937 3 0.010
regulation of gtpase activity GO:0043087 2 0.010
neurotransmitter transport GO:0006836 2 0.010
meiosis i GO:0007127 1 0.010

chp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.067
immune system disease DOID:2914 0 0.018
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.014
hematopoietic system disease DOID:74 0 0.012
sensory system disease DOID:0050155 0 0.011
inherited metabolic disorder DOID:655 0 0.010
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010