Danio rerio

0 known processes

smad3b

MAD, mothers against decapentaplegic homolog 3b (Drosophila)

(Aliases: MGC92234,madh3b,zgc:92234)

smad3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound biosynthetic process GO:0019438 217 0.520
Human Zebrafish Mouse
embryonic organ development GO:0048568 381 0.517
Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.491
Human Zebrafish Mouse
biosynthetic process GO:0009058 294 0.470
Human Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.463
Human Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.457
Human Zebrafish Mouse
nucleic acid templated transcription GO:0097659 181 0.407
Human Zebrafish Mouse
cellular biosynthetic process GO:0044249 286 0.388
Human Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.387
Human Zebrafish Mouse
digestive tract morphogenesis GO:0048546 231 0.373
Zebrafish Mouse
regionalization GO:0003002 274 0.331
Zebrafish Mouse
regulation of multicellular organismal process GO:0051239 277 0.312
Human Zebrafish Mouse Worm
regulation of transcription dna templated GO:0006355 213 0.309
Human Zebrafish Mouse
blood vessel development GO:0001568 246 0.308
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.295
Zebrafish
response to external stimulus GO:0009605 264 0.279
Human Mouse
vasculature development GO:0001944 278 0.277
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.275
Human Zebrafish Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.275
Human Zebrafish Mouse
digestive tract development GO:0048565 265 0.273
Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.271
Human Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.268
Human Zebrafish Mouse
liver development GO:0001889 96 0.267
Mouse
regulation of multicellular organismal development GO:2000026 223 0.264
Human Zebrafish Mouse
convergent extension GO:0060026 118 0.253
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.251
Human Zebrafish Mouse
regulation of response to stimulus GO:0048583 269 0.249
Human Zebrafish Mouse
hemopoiesis GO:0030097 183 0.247
Zebrafish
digestive system development GO:0055123 289 0.243
Zebrafish Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.241
Human Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.238
Human Zebrafish Mouse
chordate embryonic development GO:0043009 271 0.237
Mouse
gastrulation GO:0007369 208 0.231
Zebrafish Mouse
regulation of establishment of protein localization GO:0070201 4 0.229
Human
phosphate containing compound metabolic process GO:0006796 108 0.228
Human
macromolecule biosynthetic process GO:0009059 227 0.227
Human Zebrafish Mouse
response to chemical GO:0042221 320 0.223
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.220
Human Zebrafish Mouse
locomotion GO:0040011 313 0.220
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.218
Human Zebrafish Mouse
nucleocytoplasmic transport GO:0006913 4 0.218
Human
regulation of rna biosynthetic process GO:2001141 213 0.214
Human Zebrafish Mouse
central nervous system neuron differentiation GO:0021953 74 0.213
cellular aromatic compound metabolic process GO:0006725 295 0.208
Human Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.206
Human Zebrafish Mouse
ear morphogenesis GO:0042471 64 0.203
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.202
Human Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.190
Human Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.188
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.187
Human Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.179
Human Zebrafish Mouse
negative regulation of response to stimulus GO:0048585 104 0.178
Mouse
heterocycle metabolic process GO:0046483 290 0.178
Human Zebrafish Mouse
organic substance biosynthetic process GO:1901576 289 0.177
Human Zebrafish Mouse
regulation of rna metabolic process GO:0051252 224 0.173
Human Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.172
Human Zebrafish Mouse
multicellular organism growth GO:0035264 4 0.165
Worm
positive regulation of biological process GO:0048518 253 0.163
Human Zebrafish Mouse Worm
negative regulation of macromolecule metabolic process GO:0010605 76 0.162
Human Zebrafish Mouse
regulation of binding GO:0051098 3 0.162
Mouse
transcription dna templated GO:0006351 181 0.161
Human Zebrafish Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.159
Human Zebrafish Mouse
specification of symmetry GO:0009799 204 0.158
Zebrafish Mouse
larval development GO:0002164 2 0.157
phosphorus metabolic process GO:0006793 109 0.157
Human
optic placode formation involved in camera type eye formation GO:0046619 3 0.153
neuron differentiation GO:0030182 353 0.153
heart development GO:0007507 313 0.152
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.151
Human Zebrafish Mouse
positive regulation of transcription dna templated GO:0045893 57 0.148
Human Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.146
Human Zebrafish Mouse
transport GO:0006810 220 0.146
Human
nitrogen compound metabolic process GO:0006807 319 0.144
Human Zebrafish Mouse
aging GO:0007568 2 0.143
regulation of signaling GO:0023051 235 0.141
Human Zebrafish Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.139
Mouse
generation of neurons GO:0048699 385 0.137
stem cell maintenance GO:0019827 4 0.137
cellular nitrogen compound metabolic process GO:0034641 290 0.134
Human Zebrafish Mouse
cell motility GO:0048870 244 0.132
Zebrafish
macromolecule modification GO:0043412 111 0.130
Human
somite development GO:0061053 96 0.130
Mouse
otic vesicle morphogenesis GO:0071600 34 0.130
Zebrafish
rna metabolic process GO:0016070 219 0.129
Human Zebrafish Mouse
neuron development GO:0048666 262 0.127
regulation of gene expression GO:0010468 265 0.126
Human Zebrafish Mouse
connective tissue development GO:0061448 99 0.126
Mouse
cellular protein metabolic process GO:0044267 129 0.125
Human
regulation of multicellular organism growth GO:0040014 4 0.122
Worm
convergent extension involved in gastrulation GO:0060027 71 0.122
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.116
Human Zebrafish Mouse
positive regulation of cell communication GO:0010647 56 0.114
Human
phosphorylation GO:0016310 69 0.113
Human
cell morphogenesis GO:0000902 289 0.113
Human
establishment of protein localization to organelle GO:0072594 4 0.112
Human
positive regulation of rna biosynthetic process GO:1902680 57 0.112
Human Zebrafish Mouse
peptidyl serine phosphorylation GO:0018105 1 0.111
signal transduction GO:0007165 455 0.111
Human Zebrafish Mouse
midbrain hindbrain boundary development GO:0030917 23 0.111
head development GO:0060322 303 0.109
muscle structure development GO:0061061 196 0.105
Mouse
cellular protein modification process GO:0006464 100 0.104
Human
organic acid metabolic process GO:0006082 31 0.102
ameboidal type cell migration GO:0001667 143 0.100
Zebrafish
regulation of reproductive process GO:2000241 4 0.098
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.096
Worm
inner ear morphogenesis GO:0042472 63 0.095
Zebrafish
central nervous system development GO:0007417 387 0.093
wnt signaling pathway GO:0016055 80 0.093
Human
localization of cell GO:0051674 244 0.092
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.091
mesoderm development GO:0007498 88 0.091
Mouse
regulation of embryonic development GO:0045995 47 0.088
Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.087
Human
cell migration involved in gastrulation GO:0042074 79 0.087
Zebrafish
embryonic heart tube development GO:0035050 133 0.087
Zebrafish Mouse
organonitrogen compound metabolic process GO:1901564 74 0.083
regulation of cell size GO:0008361 29 0.083
protein metabolic process GO:0019538 183 0.083
Human
regulation of glial cell differentiation GO:0045685 4 0.081
cell morphogenesis involved in differentiation GO:0000904 195 0.081
Human
regulation of canonical wnt signaling pathway GO:0060828 34 0.080
Human
protein modification process GO:0036211 100 0.079
Human
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.079
skeletal system development GO:0001501 181 0.078
Mouse
angiogenesis GO:0001525 158 0.078
heart looping GO:0001947 94 0.076
Zebrafish Mouse
protein import into nucleus GO:0006606 3 0.076
Human
single organism metabolic process GO:0044710 217 0.075
regulation of protein transport GO:0051223 3 0.074
Human
regulation of developmental process GO:0050793 247 0.072
Human Zebrafish Mouse Worm
regulation of meiotic cell cycle GO:0051445 1 0.072
Worm
regulation of cell development GO:0060284 100 0.072
Human Zebrafish
gene expression GO:0010467 252 0.071
Human Zebrafish Mouse
positive regulation of response to stimulus GO:0048584 80 0.070
Human
cellular ketone metabolic process GO:0042180 11 0.069
embryonic organ morphogenesis GO:0048562 274 0.069
Zebrafish Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.067
Human Zebrafish Mouse
regulation of catalytic activity GO:0050790 55 0.066
Human
cell surface receptor signaling pathway GO:0007166 325 0.065
Human Zebrafish Mouse
maintenance of location GO:0051235 4 0.065
cell cycle GO:0007049 93 0.065
Human Worm
amine metabolic process GO:0009308 2 0.064
determination of left right symmetry GO:0007368 179 0.064
Zebrafish Mouse
optic placode formation GO:0001743 4 0.064
bmp signaling pathway GO:0030509 52 0.064
Zebrafish
small molecule metabolic process GO:0044281 77 0.064
immune system development GO:0002520 191 0.063
Zebrafish Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.062
skeletal system morphogenesis GO:0048705 102 0.062
Mouse
forebrain regionalization GO:0021871 4 0.061
phagocytosis GO:0006909 3 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.061
Human Zebrafish Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.060
regulation of wnt signaling pathway GO:0030111 53 0.060
Human
negative regulation of signal transduction GO:0009968 94 0.060
mediolateral intercalation GO:0060031 3 0.059
cellular component movement GO:0006928 335 0.059
Zebrafish
hepaticobiliary system development GO:0061008 98 0.059
Mouse
chemotaxis GO:0006935 104 0.059
response to stress GO:0006950 263 0.057
Human Mouse
regulation of oocyte development GO:0060281 3 0.057
Zebrafish
taxis GO:0042330 109 0.056
negative regulation of nucleic acid templated transcription GO:1903507 45 0.056
Human Zebrafish Mouse
somitogenesis GO:0001756 87 0.055
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.055
Human Zebrafish Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.054
Mouse
regulation of stem cell differentiation GO:2000736 4 0.054
Human
nuclear transport GO:0051169 4 0.054
Human
positive regulation of notch signaling pathway GO:0045747 3 0.054
single organism biosynthetic process GO:0044711 71 0.053
positive regulation of nucleic acid templated transcription GO:1903508 57 0.053
Human Zebrafish Mouse
paraxial mesoderm morphogenesis GO:0048340 2 0.052
Mouse
regulation of cytokine production GO:0001817 3 0.052
Human
habenula development GO:0021986 9 0.052
negative regulation of gene expression GO:0010629 65 0.051
Human Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.051
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.051
Human
response to nutrient GO:0007584 3 0.051
dorsal convergence GO:0060030 14 0.051
Zebrafish
axonogenesis GO:0007409 152 0.050
organic substance transport GO:0071702 58 0.050
Human
regulation of cytoplasmic transport GO:1903649 4 0.049
Human
growth GO:0040007 174 0.049
Human Mouse Worm
negative regulation of metabolic process GO:0009892 86 0.049
Human Zebrafish Mouse
protein import GO:0017038 3 0.049
Human
embryonic skeletal system development GO:0048706 97 0.049
Mouse
negative regulation of cellular process GO:0048523 283 0.049
Human Zebrafish Mouse Worm
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.048
determination of bilateral symmetry GO:0009855 204 0.047
Zebrafish Mouse
regulation of cell differentiation GO:0045595 142 0.047
Human Zebrafish Mouse
regulation of phosphate metabolic process GO:0019220 43 0.047
Human
axon development GO:0061564 166 0.047
oxoacid metabolic process GO:0043436 31 0.047
cell projection morphogenesis GO:0048858 244 0.047
lipid storage GO:0019915 1 0.046
lateral inhibition GO:0046331 1 0.045
establishment of localization GO:0051234 244 0.045
Human
developmental growth GO:0048589 166 0.044
Mouse Worm
synaptic target recognition GO:0008039 1 0.044
cell migration GO:0016477 237 0.043
Zebrafish
negative regulation of developmental process GO:0051093 65 0.042
Mouse
organonitrogen compound biosynthetic process GO:1901566 47 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.042
positive regulation of stress activated mapk cascade GO:0032874 3 0.042
spinal cord anterior posterior patterning GO:0021512 1 0.042
stem cell proliferation GO:0072089 4 0.042
cell death GO:0008219 121 0.041
Human
ventral spinal cord development GO:0021517 35 0.041
negative regulation of rna biosynthetic process GO:1902679 45 0.041
Human Zebrafish Mouse
negative regulation of chemotaxis GO:0050922 4 0.041
adult behavior GO:0030534 2 0.040
stem cell development GO:0048864 82 0.040
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.040
notch signaling pathway GO:0007219 35 0.040
cardiac muscle cell differentiation GO:0055007 30 0.040
single organism nuclear import GO:1902593 3 0.040
Human
regulation of apoptotic process GO:0042981 98 0.040
Human
oocyte maturation GO:0001556 4 0.040
determination of dorsal ventral asymmetry GO:0048262 34 0.040
Zebrafish
response to endogenous stimulus GO:0009719 83 0.040
Human Mouse
hindbrain morphogenesis GO:0021575 22 0.039
cartilage development GO:0051216 96 0.039
Mouse
intracellular signal transduction GO:0035556 85 0.039
Human Zebrafish
cellular component morphogenesis GO:0032989 336 0.039
Human
modification dependent protein catabolic process GO:0019941 3 0.038
dorsal ventral pattern formation GO:0009953 125 0.038
Zebrafish
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.038
transcription from rna polymerase ii promoter GO:0006366 80 0.038
Human Zebrafish Mouse
otic vesicle formation GO:0030916 27 0.038
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.037
programmed cell death GO:0012501 119 0.037
Human
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.037
regulation of circadian rhythm GO:0042752 4 0.037
epithalamus development GO:0021538 10 0.036
regulation of neurogenesis GO:0050767 87 0.036
regulation of cell activation GO:0050865 1 0.036
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.036
Human
positive regulation of transport GO:0051050 2 0.036
Human
positive regulation of cellular amine metabolic process GO:0033240 0 0.035
regulation of receptor activity GO:0010469 2 0.035
positive regulation of multicellular organismal process GO:0051240 52 0.035
Human Zebrafish Mouse Worm
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.035
pancreas development GO:0031016 84 0.035
embryonic neurocranium morphogenesis GO:0048702 15 0.035
astrocyte differentiation GO:0048708 1 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.034
Human Zebrafish Mouse
nuclear import GO:0051170 3 0.034
Human
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.034
Zebrafish
positive regulation of gene expression GO:0010628 71 0.034
Human Zebrafish Mouse
neurological system process GO:0050877 62 0.033
negative regulation of protein transport GO:0051224 3 0.033
regulation of axonogenesis GO:0050770 32 0.033
rhombomere morphogenesis GO:0021593 17 0.033
regulation of intracellular protein transport GO:0033157 3 0.033
Human
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.033
negative chemotaxis GO:0050919 1 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.033
macromolecular complex subunit organization GO:0043933 74 0.033
Human
mesodermal cell migration GO:0008078 12 0.033
cellular protein catabolic process GO:0044257 4 0.032
regulation of erk1 and erk2 cascade GO:0070372 4 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
tube morphogenesis GO:0035239 349 0.032
Zebrafish Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.032
Zebrafish
neural tube patterning GO:0021532 33 0.032
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.032
response to organic substance GO:0010033 153 0.032
Human Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.032
determination of heart left right asymmetry GO:0061371 117 0.031
Zebrafish Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.031
immune system process GO:0002376 241 0.031
Human Zebrafish Mouse
aorta morphogenesis GO:0035909 3 0.031
regulation of protein phosphorylation GO:0001932 18 0.031
Human
extrinsic apoptotic signaling pathway GO:0097191 3 0.031
Human
sprouting angiogenesis GO:0002040 53 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.030
Human Zebrafish Mouse
apoptotic process GO:0006915 116 0.030
Human
protein phosphorylation GO:0006468 47 0.030
Human
thrombocyte differentiation GO:0002574 4 0.030
spinal cord development GO:0021510 46 0.030
regulation of axon guidance GO:1902667 8 0.030
death GO:0016265 121 0.030
Human
negative regulation of catabolic process GO:0009895 3 0.030
Human
ear development GO:0043583 127 0.030
Zebrafish
anterior head development GO:0097065 2 0.030
aorta development GO:0035904 4 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.029
endothelial cell fate commitment GO:0060839 3 0.029
axon guidance GO:0007411 86 0.029
cellular amino acid metabolic process GO:0006520 7 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
negative regulation of signaling GO:0023057 96 0.029
regulation of anterior head development GO:2000742 2 0.028
mesoderm formation GO:0001707 43 0.028
Mouse
erk1 and erk2 cascade GO:0070371 4 0.028
regulation of molecular function GO:0065009 70 0.028
Human Mouse
heart field specification GO:0003128 1 0.027
regulation of oligodendrocyte differentiation GO:0048713 1 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
Human
gastrulation with mouth forming second GO:0001702 44 0.027
negative regulation of cellular biosynthetic process GO:0031327 55 0.027
Human Zebrafish Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.027
Human Zebrafish Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.027
Human Zebrafish
sensory system development GO:0048880 76 0.027
cellular amine metabolic process GO:0044106 2 0.027
regulation of circadian sleep wake cycle GO:0042749 1 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.027
Human Zebrafish Mouse
regulation of signal transduction GO:0009966 225 0.027
Human Zebrafish Mouse
myeloid cell differentiation GO:0030099 86 0.027
Zebrafish
insulin like growth factor receptor signaling pathway GO:0048009 4 0.026
blood vessel endothelial cell differentiation GO:0060837 2 0.026
hepatocyte proliferation GO:0072574 2 0.026
axis specification GO:0009798 43 0.026
proximal distal pattern formation GO:0009954 1 0.026
positive regulation of biosynthetic process GO:0009891 68 0.026
Human Zebrafish Mouse
epithelial tube morphogenesis GO:0060562 148 0.026
Zebrafish Mouse
peptidyl serine modification GO:0018209 2 0.026
brain development GO:0007420 293 0.025
regulation of protein modification process GO:0031399 29 0.025
Human
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
single organism transport GO:0044765 206 0.025
Human
inner ear development GO:0048839 126 0.025
Zebrafish
modification dependent macromolecule catabolic process GO:0043632 3 0.024
forebrain anterior posterior pattern specification GO:0021797 3 0.024
regulation of nervous system development GO:0051960 90 0.024
liver morphogenesis GO:0072576 8 0.024
negative regulation of biosynthetic process GO:0009890 55 0.024
Human Zebrafish Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.024
regulation of protein targeting GO:1903533 2 0.024
Human
system process GO:0003008 185 0.024
negative regulation of cell communication GO:0010648 96 0.023
protein secretion GO:0009306 1 0.023
regulation of cell death GO:0010941 103 0.023
Human
positive regulation of signal transduction GO:0009967 56 0.023
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.023
Human Zebrafish Mouse
morphogenesis of an epithelium GO:0002009 333 0.023
Zebrafish Mouse
anterior posterior pattern specification GO:0009952 152 0.023
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.023
Human
regulation of axon extension GO:0030516 24 0.023
heparan sulfate proteoglycan biosynthetic process GO:0015012 5 0.023
regulation of protein metabolic process GO:0051246 56 0.023
Human
cellular component biogenesis GO:0044085 178 0.023
Human
negative regulation of cell death GO:0060548 60 0.022
single organism localization GO:1902578 225 0.022
Human
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.022
meiotic nuclear division GO:0007126 4 0.022
regulation of phosphorylation GO:0042325 26 0.022
Human
semicircular canal development GO:0060872 24 0.022
regulation of cardiac muscle tissue development GO:0055024 1 0.022
negative regulation of rna metabolic process GO:0051253 48 0.022
Human Zebrafish Mouse
protein localization to nucleus GO:0034504 3 0.022
Human
cellular localization GO:0051641 97 0.022
Human
heart morphogenesis GO:0003007 156 0.022
Zebrafish Mouse
gall bladder development GO:0061010 1 0.022
rhombomere development GO:0021546 19 0.021
negative regulation of wnt signaling pathway GO:0030178 30 0.021
positive regulation of cell activation GO:0050867 1 0.021
non canonical wnt signaling pathway GO:0035567 13 0.021
fin development GO:0033333 77 0.021
response to vitamin GO:0033273 3 0.021
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.021
positive regulation of map kinase activity GO:0043406 3 0.021
mitotic cell cycle process GO:1903047 48 0.021
regulation of kinase activity GO:0043549 15 0.021
blood vessel endothelial cell migration GO:0043534 18 0.021
extracellular matrix organization GO:0030198 27 0.020
Human
appendage morphogenesis GO:0035107 56 0.020
rostrocaudal neural tube patterning GO:0021903 29 0.020
positive regulation of rna metabolic process GO:0051254 59 0.020
Human Zebrafish Mouse
cell proliferation in forebrain GO:0021846 3 0.020
wound healing GO:0042060 90 0.020
Mouse
kupffer s vesicle development GO:0070121 50 0.020
regulation of cellular response to growth factor stimulus GO:0090287 35 0.020
Human Mouse
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.020
negative regulation of secretion GO:0051048 2 0.020
positive regulation of muscle cell differentiation GO:0051149 1 0.020
neural plate regionalization GO:0060897 10 0.020
negative regulation of gliogenesis GO:0014014 1 0.020
endocrine pancreas development GO:0031018 27 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
Human
regulation of axon extension involved in axon guidance GO:0048841 6 0.020
glucose homeostasis GO:0042593 1 0.019
regulation of organ morphogenesis GO:2000027 35 0.019
Zebrafish
forebrain neuron differentiation GO:0021879 14 0.019
negative regulation of leukocyte differentiation GO:1902106 1 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
extracellular matrix assembly GO:0085029 1 0.019
negative regulation of mitosis GO:0045839 3 0.019
mucopolysaccharide metabolic process GO:1903510 2 0.019
regulation of epithelial to mesenchymal transition GO:0010717 3 0.019
Human
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.019
Human Zebrafish Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.019
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
positive regulation of jnk cascade GO:0046330 3 0.019
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.019
arterial endothelial cell differentiation GO:0060842 2 0.019
posttranscriptional regulation of gene expression GO:0010608 14 0.019
Human
reflex GO:0060004 2 0.019
neural tube development GO:0021915 62 0.018
positive regulation of cellular process GO:0048522 201 0.018
Human Zebrafish Mouse Worm
proteoglycan biosynthetic process GO:0030166 12 0.018
neuron projection morphogenesis GO:0048812 161 0.018
retinal ganglion cell axon guidance GO:0031290 35 0.018
protein acylation GO:0043543 3 0.018
nerve development GO:0021675 45 0.018
cellular response to organic substance GO:0071310 105 0.018
Human Mouse
dorsal ventral axis specification GO:0009950 14 0.018
sensory organ development GO:0007423 393 0.018
Zebrafish Mouse
ectodermal placode morphogenesis GO:0071697 32 0.018
Zebrafish
specification of axis polarity GO:0065001 4 0.018
somatic muscle development GO:0007525 4 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.018
otic placode formation GO:0043049 23 0.018
Zebrafish
autophagy GO:0006914 4 0.018
regulation of extent of cell growth GO:0061387 29 0.018
rhombomere boundary formation GO:0021654 10 0.018
embryonic heart tube morphogenesis GO:0003143 108 0.018
Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.018
Human Zebrafish Mouse
cellular component assembly GO:0022607 170 0.018
Human
positive regulation of apoptotic process GO:0043065 29 0.017
Human
response to wounding GO:0009611 116 0.017
Mouse
embryonic limb morphogenesis GO:0030326 2 0.017
response to hexose GO:0009746 3 0.017
regulation of collateral sprouting in absence of injury GO:0048696 4 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
forebrain generation of neurons GO:0021872 14 0.017
mesodermal cell differentiation GO:0048333 21 0.017
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.017
cell projection organization GO:0030030 284 0.017
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.017
positive regulation of developmental process GO:0051094 50 0.016
Human Zebrafish Mouse Worm
vesicle mediated transport GO:0016192 22 0.016
organ regeneration GO:0031100 1 0.016
coagulation GO:0050817 13 0.016
ectodermal placode formation GO:0060788 26 0.016
Zebrafish
protein complex subunit organization GO:0071822 46 0.016
Human
negative regulation of biological process GO:0048519 304 0.016
Human Zebrafish Mouse Worm
appendage development GO:0048736 80 0.016
negative regulation of cytokine production GO:0001818 1 0.016
establishment of protein localization to plasma membrane GO:0090002 1 0.016
positive regulation of oocyte development GO:0060282 1 0.016
Zebrafish
cilium morphogenesis GO:0060271 85 0.016
dorsal aorta development GO:0035907 4 0.016
neuron projection guidance GO:0097485 86 0.015
response to lipid GO:0033993 60 0.015
negative regulation of myeloid cell differentiation GO:0045638 1 0.015
regulation of body fluid levels GO:0050878 16 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
neural plate pattern specification GO:0060896 12 0.015
cell growth GO:0016049 57 0.015
Human
regulation of myelination GO:0031641 1 0.015
notochord development GO:0030903 54 0.015
developmental process involved in reproduction GO:0003006 27 0.015
Zebrafish Worm
positive regulation of developmental growth GO:0048639 6 0.015
Worm
mesenchyme development GO:0060485 127 0.015
Human Mouse
collateral sprouting in absence of injury GO:0048669 4 0.015
cell proliferation in hindbrain GO:0021534 4 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
Human
olfactory lobe development GO:0021988 4 0.015
neuron projection development GO:0031175 180 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
carbohydrate homeostasis GO:0033500 1 0.015
positive regulation of reproductive process GO:2000243 2 0.015
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.015
Human Zebrafish Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
Human
circadian sleep wake cycle sleep GO:0050802 1 0.015
organelle organization GO:0006996 227 0.014
locomotor rhythm GO:0045475 3 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
compound eye development GO:0048749 2 0.014
negative regulation of intracellular protein transport GO:0090317 3 0.014
olfactory bulb development GO:0021772 4 0.014
positive regulation of molecular function GO:0044093 33 0.014
Human
osteoblast differentiation GO:0001649 5 0.014
Mouse
peptidyl threonine phosphorylation GO:0018107 1 0.014
cell differentiation in spinal cord GO:0021515 40 0.014
phenol containing compound biosynthetic process GO:0046189 4 0.014
positive regulation of catabolic process GO:0009896 4 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
release of sequestered calcium ion into cytosol GO:0051209 3 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
regulation of chemotaxis GO:0050920 18 0.014
multi organism cellular process GO:0044764 2 0.014
Human
peripheral nervous system development GO:0007422 55 0.014
autonomic nervous system development GO:0048483 19 0.014

smad3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
musculoskeletal system disease DOID:17 0 0.031
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
connective tissue disease DOID:65 0 0.019
nervous system disease DOID:863 0 0.016
bone disease DOID:0080001 0 0.016
bone development disease DOID:0080006 0 0.014
dysostosis DOID:1934 0 0.014