Danio rerio

0 known processes

cx28.6

connexin 28.6

(Aliases: zgc:194305)

cx28.6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 244 0.137
Zebrafish
positive regulation of transport GO:0051050 2 0.093
aging GO:0007568 2 0.084
signal transduction GO:0007165 455 0.079
negative regulation of biological process GO:0048519 304 0.071
transport GO:0006810 220 0.066
Zebrafish
response to drug GO:0042493 3 0.063
ion transport GO:0006811 114 0.062
Zebrafish
single organism localization GO:1902578 225 0.061
Zebrafish
larval development GO:0002164 2 0.060
organic cyclic compound metabolic process GO:1901360 301 0.059
response to chemical GO:0042221 320 0.053
regulation of metal ion transport GO:0010959 4 0.050
cognition GO:0050890 1 0.045
regulation of biological quality GO:0065008 263 0.043
positive regulation of cell activation GO:0050867 1 0.041
regulation of metabolic process GO:0019222 359 0.040
mitochondrion organization GO:0007005 4 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
cellular response to external stimulus GO:0071496 2 0.038
response to nutrient GO:0007584 3 0.037
single organism transport GO:0044765 206 0.037
Zebrafish
homeostatic process GO:0042592 142 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
regulation of cellular metabolic process GO:0031323 320 0.035
regulation of primary metabolic process GO:0080090 311 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
protein localization to plasma membrane GO:0072659 1 0.033
amine metabolic process GO:0009308 2 0.032
system process GO:0003008 185 0.032
Zebrafish
response to external stimulus GO:0009605 264 0.032
monovalent inorganic cation transport GO:0015672 42 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
cellular component movement GO:0006928 335 0.030
exocytosis GO:0006887 1 0.030
maintenance of location GO:0051235 4 0.030
response to abiotic stimulus GO:0009628 122 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
Zebrafish
vasculature development GO:0001944 278 0.029
regulation of protein transport GO:0051223 3 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.029
regulation of signal transduction GO:0009966 225 0.029
response to stress GO:0006950 263 0.029
Zebrafish
organelle fusion GO:0048284 3 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
positive regulation of biological process GO:0048518 253 0.028
cellular response to nutrient levels GO:0031669 2 0.027
small molecule metabolic process GO:0044281 77 0.027
cellular amine metabolic process GO:0044106 2 0.027
organic acid metabolic process GO:0006082 31 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
lipid storage GO:0019915 1 0.026
carboxylic acid metabolic process GO:0019752 22 0.025
protein localization to nucleus GO:0034504 3 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
regulation of cell activation GO:0050865 1 0.025
blood vessel development GO:0001568 246 0.025
sensory organ development GO:0007423 393 0.025
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
positive regulation of cell cycle GO:0045787 3 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
skeletal system development GO:0001501 181 0.024
Zebrafish
heterocycle metabolic process GO:0046483 290 0.024
regulation of signaling GO:0023051 235 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
positive regulation of catabolic process GO:0009896 4 0.023
cellular component assembly GO:0022607 170 0.023
Zebrafish
chordate embryonic development GO:0043009 271 0.023
Zebrafish
guanosine containing compound catabolic process GO:1901069 2 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
atp catabolic process GO:0006200 4 0.023
ion transmembrane transport GO:0034220 91 0.023
Zebrafish
embryonic organ development GO:0048568 381 0.023
Zebrafish
fertilization GO:0009566 3 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
regulation of synaptic plasticity GO:0048167 1 0.022
negative regulation of cellular process GO:0048523 283 0.022
single organism metabolic process GO:0044710 217 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.022
rna biosynthetic process GO:0032774 181 0.022
ear development GO:0043583 127 0.022
Zebrafish
response to transition metal nanoparticle GO:1990267 28 0.022
locomotion GO:0040011 313 0.022
gtp metabolic process GO:0046039 4 0.021
angiogenesis GO:0001525 158 0.021
regulation of cytokine production GO:0001817 3 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
establishment of protein localization to plasma membrane GO:0090002 1 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
positive regulation of secretion GO:0051047 1 0.021
regulation of cell communication GO:0010646 232 0.021
gtp catabolic process GO:0006184 2 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
neurological system process GO:0050877 62 0.020
Zebrafish
transmembrane transport GO:0055085 120 0.020
Zebrafish
i kappab kinase nf kappab signaling GO:0007249 4 0.020
response to vitamin GO:0033273 3 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
apoptotic process GO:0006915 116 0.020
regulation of binding GO:0051098 3 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
tube morphogenesis GO:0035239 349 0.020
protein import GO:0017038 3 0.020
morphogenesis of an epithelium GO:0002009 333 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
organelle organization GO:0006996 227 0.019
Zebrafish
metal ion transport GO:0030001 58 0.019
membrane fusion GO:0061025 2 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
oxoacid metabolic process GO:0043436 31 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
carboxylic acid catabolic process GO:0046395 3 0.019
eye development GO:0001654 277 0.019
meiotic nuclear division GO:0007126 4 0.019
fatty acid biosynthetic process GO:0006633 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
negative regulation of cytokine production GO:0001818 1 0.019
brain development GO:0007420 293 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
single fertilization GO:0007338 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
single organism membrane fusion GO:0044801 2 0.018
single organism organelle organization GO:1902589 199 0.018
Zebrafish
gene expression GO:0010467 252 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of synapse organization GO:0050807 3 0.018
organic substance biosynthetic process GO:1901576 289 0.018
mononuclear cell proliferation GO:0032943 1 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
nucleic acid metabolic process GO:0090304 244 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
transcription dna templated GO:0006351 181 0.017
adult behavior GO:0030534 2 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
regulation of gene expression GO:0010468 265 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
positive regulation of cellular process GO:0048522 201 0.017
cellular response to radiation GO:0071478 4 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
anion transport GO:0006820 38 0.017
positive regulation of immune effector process GO:0002699 3 0.017
phagocytosis GO:0006909 3 0.017
blood vessel morphogenesis GO:0048514 216 0.017
leukocyte proliferation GO:0070661 1 0.017
immune system development GO:0002520 191 0.017
Zebrafish
response to organic substance GO:0010033 153 0.017
regulation of rna metabolic process GO:0051252 224 0.017
positive regulation of cytokine production GO:0001819 2 0.017
cellular ketone metabolic process GO:0042180 11 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
generation of neurons GO:0048699 385 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
regulation of calcium ion transport GO:0051924 2 0.016
cellular biosynthetic process GO:0044249 286 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
cell death GO:0008219 121 0.016
regulation of autophagy GO:0010506 3 0.016
cellular component biogenesis GO:0044085 178 0.016
Zebrafish
peptide transport GO:0015833 1 0.016
cellular response to xenobiotic stimulus GO:0071466 35 0.016
regulation of response to stimulus GO:0048583 269 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
regulation of localization GO:0032879 104 0.016
Zebrafish
protein import into nucleus GO:0006606 3 0.016
regulation of biosynthetic process GO:0009889 250 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of muscle contraction GO:0006937 3 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
cellular response to organic substance GO:0071310 105 0.015
germ line stem cell maintenance GO:0030718 2 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
cellular protein catabolic process GO:0044257 4 0.015
cytokinesis GO:0000910 3 0.015
nucleic acid templated transcription GO:0097659 181 0.015
neuron differentiation GO:0030182 353 0.015
single organism nuclear import GO:1902593 3 0.015
cell motility GO:0048870 244 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
death GO:0016265 121 0.015
multicellular organism growth GO:0035264 4 0.015
small molecule catabolic process GO:0044282 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
protein secretion GO:0009306 1 0.015
muscle structure development GO:0061061 196 0.015
Zebrafish
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.015
nuclear transport GO:0051169 4 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
Zebrafish
compound eye development GO:0048749 2 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
intracellular signal transduction GO:0035556 85 0.014
glucose import GO:0046323 2 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
regulation of protein targeting GO:1903533 2 0.014
negative regulation of protein transport GO:0051224 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
inner ear development GO:0048839 126 0.014
Zebrafish
negative regulation of signaling GO:0023057 96 0.014
epithelial cell differentiation GO:0030855 116 0.014
heart development GO:0007507 313 0.014
Zebrafish
interspecies interaction between organisms GO:0044419 4 0.014
response to other organism GO:0051707 97 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
xenobiotic metabolic process GO:0006805 4 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
response to alkaloid GO:0043279 2 0.014
regulation of protein complex assembly GO:0043254 3 0.014
multi organism process GO:0051704 134 0.014
negative regulation of nuclear division GO:0051784 3 0.014
growth GO:0040007 174 0.014
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.014
regulation of protein localization to plasma membrane GO:1903076 1 0.014
nuclear import GO:0051170 3 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
digestive system development GO:0055123 289 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
cell migration GO:0016477 237 0.013
cellular response to starvation GO:0009267 1 0.013
cell morphogenesis GO:0000902 289 0.013
developmental growth GO:0048589 166 0.013
Zebrafish
multi organism cellular process GO:0044764 2 0.013
pigmentation GO:0043473 85 0.013
Zebrafish
rna metabolic process GO:0016070 219 0.013
golgi vesicle transport GO:0048193 3 0.013
negative regulation of reproductive process GO:2000242 3 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
protein polyubiquitination GO:0000209 4 0.013
regulation of mitochondrion organization GO:0010821 1 0.013
autophagy GO:0006914 4 0.013
protein metabolic process GO:0019538 183 0.013
regulation of blood pressure GO:0008217 1 0.013
programmed cell death GO:0012501 119 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.012
cellular component morphogenesis GO:0032989 336 0.012
Zebrafish
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
negative regulation of mitosis GO:0045839 3 0.012
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
positive regulation of blood circulation GO:1903524 2 0.012
regulation of protein catabolic process GO:0042176 1 0.012
negative regulation of response to cytokine stimulus GO:0060761 2 0.012
negative regulation of secretion GO:0051048 2 0.012
chemosensory behavior GO:0007635 1 0.012
response to glucocorticoid GO:0051384 1 0.012
cellular component disassembly GO:0022411 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
protein homooligomerization GO:0051260 3 0.012
meiotic cell cycle process GO:1903046 3 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
ameboidal type cell migration GO:0001667 143 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
response to corticosteroid GO:0031960 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
membrane invagination GO:0010324 1 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
viral process GO:0016032 1 0.012
embryonic hemopoiesis GO:0035162 53 0.012
Zebrafish
developmental programmed cell death GO:0010623 4 0.012
spermatid differentiation GO:0048515 2 0.012
spermatid development GO:0007286 2 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
phagocytosis engulfment GO:0006911 1 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
lymphocyte proliferation GO:0046651 1 0.012
rna localization GO:0006403 4 0.012
organic acid catabolic process GO:0016054 3 0.012
positive regulation of glucose transport GO:0010828 1 0.012
cellular protein metabolic process GO:0044267 129 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of protein binding GO:0043393 3 0.011
localization of cell GO:0051674 244 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
Zebrafish
leukocyte mediated cytotoxicity GO:0001909 1 0.011
toxin transport GO:1901998 2 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
regulation of transporter activity GO:0032409 2 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
striated muscle cell differentiation GO:0051146 129 0.011
Zebrafish
hemopoiesis GO:0030097 183 0.011
Zebrafish
regulation of circadian rhythm GO:0042752 4 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
Zebrafish
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
camera type eye development GO:0043010 222 0.011
negative regulation of signal transduction GO:0009968 94 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
ras protein signal transduction GO:0007265 7 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of dna replication GO:0006275 3 0.011
organic substance transport GO:0071702 58 0.011
negative regulation of cell communication GO:0010648 96 0.011
regulation of organ growth GO:0046620 3 0.011
cellular response to oxygen levels GO:0071453 1 0.011
response to uv GO:0009411 3 0.011
monocarboxylic acid catabolic process GO:0072329 3 0.011
response to carbohydrate GO:0009743 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
head development GO:0060322 303 0.011
muscle organ development GO:0007517 101 0.011
cation transport GO:0006812 81 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
response to inorganic substance GO:0010035 38 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
immune system process GO:0002376 241 0.010
Zebrafish
regulation of sodium ion transport GO:0002028 2 0.010
response to radiation GO:0009314 51 0.010
calcium ion homeostasis GO:0055074 19 0.010
response to hexose GO:0009746 3 0.010
negative regulation of metabolic process GO:0009892 86 0.010
response to monosaccharide GO:0034284 3 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
pole plasm assembly GO:0007315 4 0.010
inorganic cation transmembrane transport GO:0098662 50 0.010
alcohol biosynthetic process GO:0046165 2 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
regulation of multicellular organismal process GO:0051239 277 0.010
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.010
regulation of dendrite development GO:0050773 3 0.010
cytoskeleton organization GO:0007010 96 0.010
Zebrafish
reactive oxygen species biosynthetic process GO:1903409 1 0.010
cell killing GO:0001906 2 0.010

cx28.6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.013
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.010