Danio rerio

24 known processes

her7

hairy and enhancer of split related-7

(Aliases: cb715)

her7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 274 0.973
regulation of nitrogen compound metabolic process GO:0051171 251 0.951
Zebrafish Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.936
somitogenesis GO:0001756 87 0.926
rna biosynthetic process GO:0032774 181 0.923
Zebrafish Fly
transcription dna templated GO:0006351 181 0.919
Zebrafish Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.917
Zebrafish Fly
regulation of multicellular organismal development GO:2000026 223 0.915
Zebrafish Fly
nucleic acid templated transcription GO:0097659 181 0.915
Zebrafish Fly
anterior posterior pattern specification GO:0009952 152 0.900
heterocycle biosynthetic process GO:0018130 215 0.898
Zebrafish Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.898
Zebrafish Fly
regulation of cellular metabolic process GO:0031323 320 0.880
Zebrafish Fly
somite development GO:0061053 96 0.874
nitrogen compound metabolic process GO:0006807 319 0.867
Zebrafish Fly
endoderm development GO:0007492 49 0.865
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.846
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.840
regulation of rna biosynthetic process GO:2001141 213 0.839
Zebrafish Fly
regulation of multicellular organismal process GO:0051239 277 0.836
Zebrafish Fly
cellular aromatic compound metabolic process GO:0006725 295 0.833
Zebrafish Fly
cellular biosynthetic process GO:0044249 286 0.826
Zebrafish Fly
regulation of rna metabolic process GO:0051252 224 0.814
Zebrafish Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.805
Zebrafish Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.804
Zebrafish Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.780
Zebrafish Fly
regulation of metabolic process GO:0019222 359 0.776
Zebrafish Worm Fly
endodermal cell fate specification GO:0001714 17 0.770
regulation of macromolecule metabolic process GO:0060255 317 0.754
Zebrafish Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.749
Zebrafish Fly
cardiac muscle tissue development GO:0048738 48 0.742
aromatic compound biosynthetic process GO:0019438 217 0.719
Zebrafish Fly
somite rostral caudal axis specification GO:0032525 5 0.718
nucleic acid metabolic process GO:0090304 244 0.701
Zebrafish Fly
vasculature development GO:0001944 278 0.693
negative regulation of biological process GO:0048519 304 0.690
Zebrafish Worm Fly
gene expression GO:0010467 252 0.687
Zebrafish Worm Fly
mesenchyme development GO:0060485 127 0.682
blood vessel endothelial cell differentiation GO:0060837 2 0.662
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.651
Zebrafish Fly
cardiac conduction system development GO:0003161 1 0.650
chordate embryonic development GO:0043009 271 0.648
bmp signaling pathway involved in heart development GO:0061312 15 0.646
regulation of cellular biosynthetic process GO:0031326 245 0.644
Zebrafish Fly
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.636
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.623
digestive tract development GO:0048565 265 0.621
biosynthetic process GO:0009058 294 0.620
Zebrafish Fly
generation of neurons GO:0048699 385 0.612
Zebrafish Fly
morphogenesis of an epithelium GO:0002009 333 0.611
muscle structure development GO:0061061 196 0.604
gliogenesis GO:0042063 45 0.595
Zebrafish
septum transversum development GO:0003343 4 0.581
bmp signaling pathway involved in heart jogging GO:0003303 14 0.579
arterial endothelial cell differentiation GO:0060842 2 0.568
regulation of primary metabolic process GO:0080090 311 0.564
Zebrafish Fly
heterocycle metabolic process GO:0046483 290 0.562
Zebrafish Fly
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.561
cellular macromolecule biosynthetic process GO:0034645 224 0.560
Zebrafish Fly
regulation of endodermal cell fate specification GO:0042663 15 0.554
signal transduction GO:0007165 455 0.548
Zebrafish
determination of left right symmetry GO:0007368 179 0.545
segmentation GO:0035282 97 0.543
regulation of transcription dna templated GO:0006355 213 0.543
Zebrafish Fly
muscle organ development GO:0007517 101 0.537
digestive system development GO:0055123 289 0.536
somite specification GO:0001757 12 0.523
formation of primary germ layer GO:0001704 62 0.517
muscle cell differentiation GO:0042692 139 0.513
gastrulation GO:0007369 208 0.511
organic cyclic compound metabolic process GO:1901360 301 0.506
Zebrafish Fly
macromolecule biosynthetic process GO:0009059 227 0.500
Zebrafish Fly
regulation of biosynthetic process GO:0009889 250 0.484
Zebrafish Fly
cellular macromolecule metabolic process GO:0044260 391 0.482
Zebrafish Fly
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.475
localization of cell GO:0051674 244 0.473
specification of symmetry GO:0009799 204 0.469
positive regulation of gene expression GO:0010628 71 0.466
tube morphogenesis GO:0035239 349 0.464
regulation of endodermal cell differentiation GO:1903224 15 0.461
positive regulation of biological process GO:0048518 253 0.461
Zebrafish Fly
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.456
heart valve formation GO:0003188 4 0.454
rna metabolic process GO:0016070 219 0.451
Zebrafish Fly
cell motility GO:0048870 244 0.439
atrioventricular valve formation GO:0003190 3 0.431
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.430
Fly
skeletal muscle organ development GO:0060538 78 0.428
liver development GO:0001889 96 0.421
endodermal cell differentiation GO:0035987 19 0.419
nucleobase containing compound metabolic process GO:0006139 274 0.417
Zebrafish Fly
regulation of organ morphogenesis GO:2000027 35 0.411
regulation of embryonic development GO:0045995 47 0.408
blood vessel development GO:0001568 246 0.408
ear development GO:0043583 127 0.406
regulation of gene expression GO:0010468 265 0.401
Zebrafish Worm Fly
camera type eye photoreceptor cell differentiation GO:0060219 19 0.399
embryonic heart tube development GO:0035050 133 0.398
negative regulation of cellular process GO:0048523 283 0.396
Zebrafish Fly
mesoderm morphogenesis GO:0048332 51 0.380
photoreceptor cell fate commitment GO:0046552 1 0.377
neuron development GO:0048666 262 0.374
Zebrafish Fly
striated muscle cell differentiation GO:0051146 129 0.370
heart contraction GO:0060047 71 0.360
organic substance biosynthetic process GO:1901576 289 0.357
Zebrafish Fly
kupffer s vesicle development GO:0070121 50 0.351
positive regulation of cellular metabolic process GO:0031325 94 0.351
Zebrafish
stem cell development GO:0048864 82 0.350
cardiac cell fate commitment GO:0060911 1 0.347
homeostatic process GO:0042592 142 0.346
mesodermal cell fate specification GO:0007501 12 0.332
limb bud formation GO:0060174 2 0.330
specification of organ position GO:0010159 3 0.330
regulation of mesodermal cell fate specification GO:0042661 9 0.317
negative regulation of gastrulation GO:2000542 11 0.315
pharyngeal muscle development GO:0043282 4 0.311
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.306
determination of bilateral symmetry GO:0009855 204 0.306
stem cell differentiation GO:0048863 117 0.304
heart process GO:0003015 71 0.303
muscle tissue development GO:0060537 110 0.300
heart jogging GO:0003146 40 0.299
positive regulation of metabolic process GO:0009893 108 0.292
Zebrafish
bmp signaling pathway GO:0030509 52 0.286
proepicardium development GO:0003342 4 0.286
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.284
negative regulation of gene expression GO:0010629 65 0.284
Zebrafish Worm Fly
regulation of neurogenesis GO:0050767 87 0.282
Zebrafish Fly
endoderm formation GO:0001706 29 0.281
cardiac atrium morphogenesis GO:0003209 2 0.274
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.274
cell proliferation involved in heart morphogenesis GO:0061323 2 0.268
cell migration involved in heart development GO:0060973 22 0.264
cell surface receptor signaling pathway GO:0007166 325 0.263
Zebrafish
pericardium morphogenesis GO:0003344 1 0.259
negative regulation of mesodermal cell fate specification GO:0042662 3 0.258
atrial ventricular junction remodeling GO:0003294 2 0.257
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.254
larval development GO:0002164 2 0.254
blood vessel morphogenesis GO:0048514 216 0.252
positive regulation of cellular biosynthetic process GO:0031328 68 0.244
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.244
Zebrafish Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.238
Zebrafish Fly
heart looping GO:0001947 94 0.238
mesoderm development GO:0007498 88 0.234
Fly
positive regulation of stem cell proliferation GO:2000648 1 0.234
Fly
cell migration GO:0016477 237 0.233
locomotion GO:0040011 313 0.231
Fly
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.229
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.229
Zebrafish Fly
epithelial cell differentiation GO:0030855 116 0.229
Worm
heart development GO:0007507 313 0.228
ameboidal type cell migration GO:0001667 143 0.228
negative regulation of metabolic process GO:0009892 86 0.227
Zebrafish Worm Fly
immune system process GO:0002376 241 0.223
regulation of developmental process GO:0050793 247 0.221
Zebrafish Fly
anterior posterior axis specification GO:0009948 20 0.220
positive regulation of muscle organ development GO:0048636 1 0.220
blood circulation GO:0008015 87 0.216
retina morphogenesis in camera type eye GO:0060042 79 0.215
embryonic pattern specification GO:0009880 44 0.212
negative regulation of cell differentiation GO:0045596 46 0.209
Zebrafish
cell migration to the midline involved in heart development GO:0003318 12 0.200
mesendoderm development GO:0048382 10 0.197
brain development GO:0007420 293 0.196
Zebrafish Fly
hepatocyte differentiation GO:0070365 1 0.191
positive regulation of biosynthetic process GO:0009891 68 0.189
negative regulation of rna metabolic process GO:0051253 48 0.188
Zebrafish Fly
axis specification GO:0009798 43 0.188
regulation of cell proliferation GO:0042127 37 0.186
Fly
endodermal cell fate commitment GO:0001711 18 0.186
negative regulation of endodermal cell differentiation GO:1903225 8 0.185
intermediate mesoderm development GO:0048389 2 0.183
photoreceptor cell differentiation GO:0046530 55 0.182
Fly
aorta morphogenesis GO:0035909 3 0.181
regulation of mesoderm development GO:2000380 11 0.178
neural retina development GO:0003407 49 0.177
eye photoreceptor cell differentiation GO:0001754 45 0.175
Fly
paraxial mesoderm development GO:0048339 8 0.174
mesenchymal cell development GO:0014031 78 0.173
retinal rod cell development GO:0046548 4 0.172
sensory organ morphogenesis GO:0090596 200 0.167
Fly
pronephros morphogenesis GO:0072114 14 0.165
developmental growth GO:0048589 166 0.164
mesodermal cell differentiation GO:0048333 21 0.163
embryonic heart tube morphogenesis GO:0003143 108 0.163
cell migration involved in gastrulation GO:0042074 79 0.163
angiogenesis GO:0001525 158 0.163
cardiac chamber formation GO:0003207 4 0.162
negative regulation of macromolecule metabolic process GO:0010605 76 0.162
Zebrafish Worm Fly
negative regulation of biosynthetic process GO:0009890 55 0.162
Zebrafish Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.161
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.158
regulation of gastrulation GO:0010470 24 0.158
epithelial tube morphogenesis GO:0060562 148 0.157
retina layer formation GO:0010842 24 0.154
notochord development GO:0030903 54 0.154
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.154
Zebrafish Fly
regulation of bmp signaling pathway GO:0030510 39 0.151
morphogenesis of an epithelial fold GO:0060571 1 0.149
cellular component movement GO:0006928 335 0.146
positive regulation of muscle tissue development GO:1901863 1 0.145
negative regulation of neurogenesis GO:0050768 20 0.142
Zebrafish
cell adhesion mediated by integrin GO:0033627 1 0.139
multicellular organismal reproductive process GO:0048609 35 0.139
axial mesoderm formation GO:0048320 4 0.138
photoreceptor cell fate specification GO:0043704 1 0.138
neural tube patterning GO:0021532 33 0.137
Zebrafish
spinal cord motor neuron differentiation GO:0021522 26 0.136
positive regulation of cell fate commitment GO:0010455 1 0.135
transcription from rna polymerase ii promoter GO:0006366 80 0.135
Fly
convergent extension GO:0060026 118 0.133
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.132
cardiac muscle cell differentiation GO:0055007 30 0.130
heart morphogenesis GO:0003007 156 0.129
regulation of stem cell differentiation GO:2000736 4 0.128
heart formation GO:0060914 13 0.128
hematopoietic stem cell differentiation GO:0060218 20 0.127
negative regulation of cellular biosynthetic process GO:0031327 55 0.124
Zebrafish Fly
pronephros development GO:0048793 69 0.124
organ formation GO:0048645 17 0.122
Fly
positive regulation of cellular process GO:0048522 201 0.122
Zebrafish Fly
morphogenesis of an epithelial sheet GO:0002011 49 0.122
multi organism process GO:0051704 134 0.122
negative regulation of nucleic acid templated transcription GO:1903507 45 0.118
Zebrafish Fly
regulation of heart morphogenesis GO:2000826 17 0.118
positive regulation of rna biosynthetic process GO:1902680 57 0.116
camera type eye development GO:0043010 222 0.116
nerve development GO:0021675 45 0.116
dorsal ventral pattern formation GO:0009953 125 0.114
Fly
cell projection organization GO:0030030 284 0.114
Zebrafish Fly
neuron differentiation GO:0030182 353 0.114
Zebrafish Fly
astrocyte differentiation GO:0048708 1 0.114
sensory organ development GO:0007423 393 0.113
Zebrafish Fly
lateral mesoderm development GO:0048368 23 0.113
cardiocyte differentiation GO:0035051 44 0.112
system process GO:0003008 185 0.111
Fly
cardioblast migration GO:0003260 7 0.111
cell fate commitment GO:0045165 99 0.110
Worm Fly
positive regulation of rna metabolic process GO:0051254 59 0.110
response to stress GO:0006950 263 0.110
Fly
cardiac atrium development GO:0003230 4 0.109
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.109
hematopoietic or lymphoid organ development GO:0048534 191 0.109
negative regulation of cellular metabolic process GO:0031324 77 0.105
Zebrafish Fly
response to abiotic stimulus GO:0009628 122 0.104
regulation of biological quality GO:0065008 263 0.104
positive regulation of striated muscle tissue development GO:0045844 1 0.104
head development GO:0060322 303 0.103
Zebrafish Fly
neuron projection development GO:0031175 180 0.101
Zebrafish Fly
determination of heart left right asymmetry GO:0061371 117 0.100
regulation of system process GO:0044057 40 0.099
negative regulation of endodermal cell fate specification GO:0042664 8 0.099
rostrocaudal neural tube patterning GO:0021903 29 0.099
Zebrafish
eye morphogenesis GO:0048592 144 0.098
Fly
single organism reproductive process GO:0044702 40 0.098
cellular amine metabolic process GO:0044106 2 0.096
central nervous system development GO:0007417 387 0.096
Zebrafish Fly
embryonic hemopoiesis GO:0035162 53 0.095
neural crest cell differentiation GO:0014033 72 0.095
appendage development GO:0048736 80 0.095
aging GO:0007568 2 0.093
embryonic organ development GO:0048568 381 0.093
Zebrafish
regulation of response to stimulus GO:0048583 269 0.092
Fly
erythrocyte differentiation GO:0030218 54 0.092
multi organism reproductive process GO:0044703 36 0.091
regulation of cell cycle GO:0051726 52 0.091
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.091
Zebrafish
regulation of signal transduction GO:0009966 225 0.090
ventral spinal cord development GO:0021517 35 0.089
determination of dorsal ventral asymmetry GO:0048262 34 0.089
somatic muscle development GO:0007525 4 0.088
mesoderm formation GO:0001707 43 0.088
skeletal system development GO:0001501 181 0.088
regulation of oocyte development GO:0060281 3 0.087
stem cell maintenance GO:0019827 4 0.086
regulation of cardiac muscle tissue development GO:0055024 1 0.084
atrioventricular valve morphogenesis GO:0003181 6 0.084
cellular response to lipopolysaccharide GO:0071222 3 0.084
oocyte maturation GO:0001556 4 0.084
heart field specification GO:0003128 1 0.084
positive regulation of nucleic acid templated transcription GO:1903508 57 0.083
cell death GO:0008219 121 0.082
negative regulation of cell communication GO:0010648 96 0.080
single organism organelle organization GO:1902589 199 0.080
striated muscle tissue development GO:0014706 110 0.079
positive regulation of developmental process GO:0051094 50 0.079
Fly
ear morphogenesis GO:0042471 64 0.078
embryonic axis specification GO:0000578 12 0.078
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.078
negative regulation of transcription dna templated GO:0045892 45 0.078
Zebrafish Fly
positive regulation of cell proliferation GO:0008284 15 0.076
Fly
cell cycle GO:0007049 93 0.075
Zebrafish
cranial nerve development GO:0021545 42 0.073
kidney epithelium development GO:0072073 23 0.072
negative regulation of rna biosynthetic process GO:1902679 45 0.072
Zebrafish Fly
negative regulation of multicellular organismal process GO:0051241 69 0.072
Zebrafish
cell fate specification GO:0001708 68 0.071
Worm
reproduction GO:0000003 40 0.068
regulation of synapse assembly GO:0051963 3 0.067
single organism biosynthetic process GO:0044711 71 0.067
response to organic substance GO:0010033 153 0.067
eye photoreceptor cell development GO:0042462 30 0.066
aorta development GO:0035904 4 0.066
exocrine system development GO:0035272 28 0.065
regulation of cell communication GO:0010646 232 0.065
fin development GO:0033333 77 0.065
growth GO:0040007 174 0.064
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.063
Zebrafish Fly
regulation of cell death GO:0010941 103 0.063
retina development in camera type eye GO:0060041 146 0.063
intrahepatic bile duct development GO:0035622 11 0.062
single fertilization GO:0007338 3 0.062
negative regulation of response to stimulus GO:0048585 104 0.061
negative regulation of oocyte development GO:0060283 2 0.061
heart valve morphogenesis GO:0003179 8 0.061
regulation of cell matrix adhesion GO:0001952 1 0.061
wound healing GO:0042060 90 0.061
positive regulation of transport GO:0051050 2 0.061
cell proliferation GO:0008283 80 0.061
Fly
hepaticobiliary system development GO:0061008 98 0.060
positive regulation of signaling GO:0023056 56 0.059
negative regulation of reproductive process GO:2000242 3 0.059
stem cell proliferation GO:0072089 4 0.058
Fly
developmental maturation GO:0021700 34 0.057
cell morphogenesis GO:0000902 289 0.056
Zebrafish Fly
pericardium development GO:0060039 1 0.056
eye development GO:0001654 277 0.055
Zebrafish Fly
glomerulus vasculature development GO:0072012 2 0.055
response to endogenous stimulus GO:0009719 83 0.055
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.055
response to chemical GO:0042221 320 0.054
fin morphogenesis GO:0033334 53 0.054
foregut morphogenesis GO:0007440 4 0.054
apoptotic process GO:0006915 116 0.054
establishment of localization GO:0051234 244 0.053
skeletal muscle tissue development GO:0007519 67 0.053
appendage morphogenesis GO:0035107 56 0.052
cardiogenic plate morphogenesis GO:0003142 1 0.052
amine metabolic process GO:0009308 2 0.052
cardiac chamber development GO:0003205 19 0.051
regulation of cell fate specification GO:0042659 20 0.051
inner ear morphogenesis GO:0042472 63 0.050
negative regulation of developmental process GO:0051093 65 0.050
Zebrafish
renal system vasculature development GO:0061437 2 0.050
axial mesodermal cell fate specification GO:0048327 3 0.049
mesenchymal cell differentiation GO:0048762 87 0.049
midbrain hindbrain boundary development GO:0030917 23 0.049
Zebrafish
regulation of reproductive process GO:2000241 4 0.049
cell cell signaling GO:0007267 52 0.049
regulation of neural precursor cell proliferation GO:2000177 3 0.049
Fly
regulation of signaling GO:0023051 235 0.049
organelle organization GO:0006996 227 0.048
negative regulation of cell development GO:0010721 26 0.048
Zebrafish
diencephalon development GO:0021536 58 0.048
Zebrafish
positive regulation of striated muscle cell differentiation GO:0051155 1 0.047
fatty acid biosynthetic process GO:0006633 4 0.047
epidermis development GO:0008544 48 0.047
Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.047
hemopoiesis GO:0030097 183 0.047
cardiac endothelial cell differentiation GO:0003348 5 0.046
segment specification GO:0007379 12 0.046
embryonic foregut morphogenesis GO:0048617 1 0.046
cellular component assembly GO:0022607 170 0.046
programmed cell death GO:0012501 119 0.046
cell differentiation in spinal cord GO:0021515 40 0.045
regulation of stem cell proliferation GO:0072091 2 0.045
Fly
regulation of wnt signaling pathway GO:0030111 53 0.045
germ cell development GO:0007281 22 0.045
notochord morphogenesis GO:0048570 17 0.045
dorsal aorta morphogenesis GO:0035912 3 0.044
regulation of inner ear receptor cell differentiation GO:2000980 1 0.044
endocardium morphogenesis GO:0003160 4 0.044
convergent extension involved in organogenesis GO:0060029 10 0.043
response to external stimulus GO:0009605 264 0.043
Fly
regulation of skeletal muscle fiber development GO:0048742 2 0.042
mesodermal cell fate commitment GO:0001710 14 0.042
notch signaling pathway GO:0007219 35 0.042
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.042
regulation of skeletal muscle tissue development GO:0048641 4 0.042
negative regulation of mesoderm development GO:2000381 5 0.042
renal system development GO:0072001 94 0.042
regulation of notch signaling pathway GO:0008593 16 0.042
muscle fiber development GO:0048747 52 0.042
immune system development GO:0002520 191 0.041
glomerulus development GO:0032835 27 0.041
neuron fate commitment GO:0048663 26 0.041
cartilage morphogenesis GO:0060536 13 0.041
vasculogenesis GO:0001570 41 0.041
positive regulation of neurogenesis GO:0050769 24 0.041
Fly
heart valve development GO:0003170 14 0.040
positive regulation of transcription dna templated GO:0045893 57 0.040
positive regulation of muscle cell differentiation GO:0051149 1 0.039
compound eye development GO:0048749 2 0.039
Fly
regulation of localization GO:0032879 104 0.039
cellular amino acid metabolic process GO:0006520 7 0.039
positive regulation of multicellular organismal process GO:0051240 52 0.039
Fly
response to bacterium GO:0009617 58 0.038
somatic motor neuron differentiation GO:0021523 5 0.038
developmental growth involved in morphogenesis GO:0060560 86 0.038
negative regulation of signal transduction GO:0009968 94 0.037
negative regulation of signaling GO:0023057 96 0.037
homeostasis of number of cells GO:0048872 62 0.037
response to oxygen containing compound GO:1901700 55 0.037
cellular component biogenesis GO:0044085 178 0.036
skeletal system morphogenesis GO:0048705 102 0.036
floor plate morphogenesis GO:0033505 12 0.036
response to monosaccharide GO:0034284 3 0.036
cellular response to endogenous stimulus GO:0071495 68 0.035
regulation of blood circulation GO:1903522 32 0.035
nephric duct morphogenesis GO:0072178 7 0.035
forebrain development GO:0030900 96 0.035
Zebrafish
tissue remodeling GO:0048771 4 0.035
semicircular canal morphogenesis GO:0048752 18 0.035
regulation of canonical wnt signaling pathway GO:0060828 34 0.035
neural tube development GO:0021915 62 0.035
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.034
endodermal cell fate determination GO:0007493 2 0.034
regulation of cell fate commitment GO:0010453 22 0.034
gastrulation with mouth forming second GO:0001702 44 0.034
glial cell differentiation GO:0010001 42 0.034
sexual reproduction GO:0019953 36 0.034
artery development GO:0060840 22 0.034
stem cell division GO:0017145 1 0.033
regulation of cell migration GO:0030334 40 0.033
neural crest cell migration GO:0001755 42 0.033
regulation of synapse organization GO:0050807 3 0.033
organelle assembly GO:0070925 110 0.033
neuron projection morphogenesis GO:0048812 161 0.033
Zebrafish Fly
endothelial cell fate commitment GO:0060839 3 0.033
auditory receptor cell fate commitment GO:0009912 4 0.033
regulation of cell maturation GO:1903429 1 0.033
neural crest cell development GO:0014032 62 0.032
pronephric duct development GO:0039022 13 0.032
skin development GO:0043588 54 0.032
Worm
protein localization to nucleus GO:0034504 3 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
oxoacid metabolic process GO:0043436 31 0.031
cellular response to biotic stimulus GO:0071216 3 0.031
small molecule metabolic process GO:0044281 77 0.030
positive regulation of programmed cell death GO:0043068 29 0.030
artery morphogenesis GO:0048844 14 0.030
kidney vasculature development GO:0061440 2 0.030
positive regulation of cell cycle GO:0045787 3 0.030
Zebrafish
response to external biotic stimulus GO:0043207 97 0.030
positive regulation of mesoderm development GO:2000382 1 0.029
regulation of cytokine production GO:0001817 3 0.029
regulation of muscle organ development GO:0048634 9 0.029
left right pattern formation GO:0060972 19 0.028
rhombomere 5 morphogenesis GO:0021664 1 0.028
outflow tract morphogenesis GO:0003151 1 0.028
dorsal aorta development GO:0035907 4 0.028
gland development GO:0048732 143 0.028
regulation of cell motility GO:2000145 46 0.028
axonogenesis GO:0007409 152 0.028
Zebrafish
connective tissue development GO:0061448 99 0.027
sensory perception of chemical stimulus GO:0007606 3 0.027
optic nerve development GO:0021554 15 0.027
cell migration involved in heart formation GO:0060974 10 0.027
cellular response to stress GO:0033554 62 0.027
Fly
spinal cord development GO:0021510 46 0.027
atrioventricular valve development GO:0003171 11 0.027
death GO:0016265 121 0.026
cell adhesion GO:0007155 40 0.026
regulation of programmed cell death GO:0043067 101 0.026
metencephalon development GO:0022037 27 0.026
wnt signaling pathway GO:0016055 80 0.026
regulation of nervous system development GO:0051960 90 0.026
Zebrafish Fly
extracellular matrix assembly GO:0085029 1 0.026
embryonic appendage morphogenesis GO:0035113 30 0.026
positive regulation of cell communication GO:0010647 56 0.026
regulation of heart growth GO:0060420 2 0.026
kidney development GO:0001822 92 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
semicircular canal development GO:0060872 24 0.026
positive regulation of notch signaling pathway GO:0045747 3 0.025
embryonic skeletal system morphogenesis GO:0048704 93 0.025
reproductive process GO:0022414 40 0.025
Worm
cellular response to organic substance GO:0071310 105 0.025
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.025
germ line stem cell maintenance GO:0030718 2 0.025
single organism transport GO:0044765 206 0.025
regulation of cell development GO:0060284 100 0.025
Zebrafish Fly
pancreas development GO:0031016 84 0.025
nephron morphogenesis GO:0072028 2 0.025
urogenital system development GO:0001655 97 0.024

her7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.621
bone development disease DOID:0080006 0 0.160
bone disease DOID:0080001 0 0.160
dysostosis DOID:1934 0 0.160
musculoskeletal system disease DOID:17 0 0.160
connective tissue disease DOID:65 0 0.160
nervous system disease DOID:863 0 0.050
retinal disease DOID:5679 0 0.030
sensory system disease DOID:0050155 0 0.030
eye and adnexa disease DOID:1492 0 0.030
eye disease DOID:5614 0 0.030
disease of mental health DOID:150 0 0.024
developmental disorder of mental health DOID:0060037 0 0.024