Danio rerio

0 known processes

irf2a

interferon regulatory factor 2a

(Aliases: fc74h04,wu:fc74h04,zgc:76951)

irf2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.112
aging GO:0007568 2 0.054
maintenance of location GO:0051235 4 0.052
multicellular organism growth GO:0035264 4 0.049
regulation of multicellular organism growth GO:0040014 4 0.037
phagocytosis GO:0006909 3 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
Human
lipid storage GO:0019915 1 0.035
positive regulation of transport GO:0051050 2 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
Human
ubiquitin dependent protein catabolic process GO:0006511 3 0.034
nuclear transport GO:0051169 4 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
cellular protein catabolic process GO:0044257 4 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
regulation of cytokine production GO:0001817 3 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.032
cellular macromolecule metabolic process GO:0044260 391 0.031
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.031
mitochondrion organization GO:0007005 4 0.031
amine metabolic process GO:0009308 2 0.031
heterocycle metabolic process GO:0046483 290 0.030
Human
modification dependent protein catabolic process GO:0019941 3 0.030
signal transduction GO:0007165 455 0.030
regulation of metabolic process GO:0019222 359 0.029
Human
positive regulation of catabolic process GO:0009896 4 0.029
gene expression GO:0010467 252 0.028
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.028
Human
cellular amine metabolic process GO:0044106 2 0.028
meiotic nuclear division GO:0007126 4 0.028
protein import GO:0017038 3 0.027
cytokinesis GO:0000910 3 0.027
regulation of establishment of protein localization GO:0070201 4 0.026
regulation of mrna processing GO:0050684 3 0.026
regulation of protein transport GO:0051223 3 0.026
response to chemical GO:0042221 320 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
protein localization to nucleus GO:0034504 3 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
Human
nuclear import GO:0051170 3 0.025
protein acetylation GO:0006473 2 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
Human
regulation of cellular metabolic process GO:0031323 320 0.025
Human
rna metabolic process GO:0016070 219 0.025
Human
regulation of cell shape GO:0008360 1 0.024
proteasomal protein catabolic process GO:0010498 2 0.024
organic substance biosynthetic process GO:1901576 289 0.024
Human
positive regulation of map kinase activity GO:0043406 3 0.024
organelle fusion GO:0048284 3 0.024
response to drug GO:0042493 3 0.024
nucleic acid metabolic process GO:0090304 244 0.024
Human
autophagy GO:0006914 4 0.024
central nervous system development GO:0007417 387 0.024
positive regulation of cell cycle GO:0045787 3 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
regulation of cell activation GO:0050865 1 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
gtp metabolic process GO:0046039 4 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
biosynthetic process GO:0009058 294 0.023
Human
stem cell maintenance GO:0019827 4 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
regulation of protein complex assembly GO:0043254 3 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
regulation of protein catabolic process GO:0042176 1 0.023
single organism membrane fusion GO:0044801 2 0.023
protein secretion GO:0009306 1 0.023
membrane fusion GO:0061025 2 0.023
immune system process GO:0002376 241 0.022
oxoacid metabolic process GO:0043436 31 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
Human
cellular response to external stimulus GO:0071496 2 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
regulation of gene expression GO:0010468 265 0.022
Human
transcription dna templated GO:0006351 181 0.022
Human
cellular ketone metabolic process GO:0042180 11 0.022
stem cell proliferation GO:0072089 4 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.022
gtp catabolic process GO:0006184 2 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
single organism nuclear import GO:1902593 3 0.022
regulation of response to stimulus GO:0048583 269 0.022
nucleic acid templated transcription GO:0097659 181 0.022
Human
positive regulation of biological process GO:0048518 253 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
Human
macromolecule biosynthetic process GO:0009059 227 0.021
Human
cellular amino acid metabolic process GO:0006520 7 0.021
peptidyl lysine acetylation GO:0018394 2 0.021
single organism metabolic process GO:0044710 217 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
protein acylation GO:0043543 3 0.021
internal protein amino acid acetylation GO:0006475 2 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.021
cellular component morphogenesis GO:0032989 336 0.021
cellular component biogenesis GO:0044085 178 0.021
regulation of rna metabolic process GO:0051252 224 0.021
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of developmental process GO:0050793 247 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
internal peptidyl lysine acetylation GO:0018393 2 0.020
protein import into nucleus GO:0006606 3 0.020
positive regulation of cytokine production GO:0001819 2 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
alternative mrna splicing via spliceosome GO:0000380 1 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
Human
cellular biosynthetic process GO:0044249 286 0.020
Human
regulation of primary metabolic process GO:0080090 311 0.020
Human
regulation of binding GO:0051098 3 0.020
tissue remodeling GO:0048771 4 0.020
regulation of mrna splicing via spliceosome GO:0048024 3 0.020
small molecule metabolic process GO:0044281 77 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
protein metabolic process GO:0019538 183 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
protein localization to plasma membrane GO:0072659 1 0.019
regulation of signaling GO:0023051 235 0.019
leukocyte proliferation GO:0070661 1 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
Human
meiotic cell cycle process GO:1903046 3 0.019
cell morphogenesis GO:0000902 289 0.019
regulation of biosynthetic process GO:0009889 250 0.019
Human
positive regulation of translation GO:0045727 1 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
Human
rna biosynthetic process GO:0032774 181 0.019
Human
atp catabolic process GO:0006200 4 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
Human
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
cellular component assembly GO:0022607 170 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
Human
regulation of protein targeting GO:1903533 2 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
Human
negative regulation of biological process GO:0048519 304 0.018
hemopoiesis GO:0030097 183 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
Human
protein dephosphorylation GO:0006470 3 0.018
cellular component disassembly GO:0022411 1 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
response to stress GO:0006950 263 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
cellular response to starvation GO:0009267 1 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
protein targeting to nucleus GO:0044744 3 0.018
organelle organization GO:0006996 227 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
Human
phagocytosis engulfment GO:0006911 1 0.018
regulation of cell communication GO:0010646 232 0.018
cellular response to biotic stimulus GO:0071216 3 0.017
response to uv GO:0009411 3 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
Human
transport GO:0006810 220 0.017
regulation of biological quality GO:0065008 263 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
regulation of signal transduction GO:0009966 225 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
cellular amide metabolic process GO:0043603 4 0.017
cellular component movement GO:0006928 335 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
positive regulation of cell activation GO:0050867 1 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.017
golgi vesicle transport GO:0048193 3 0.017
mononuclear cell proliferation GO:0032943 1 0.017
digestive system development GO:0055123 289 0.016
cellular response to nutrient levels GO:0031669 2 0.016
regulation of transcription dna templated GO:0006355 213 0.016
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
negative regulation of cellular process GO:0048523 283 0.016
immune system development GO:0002520 191 0.016
growth GO:0040007 174 0.016
adult behavior GO:0030534 2 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
meiotic chromosome segregation GO:0045132 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
negative regulation of cytokine production GO:0001818 1 0.016
protein polymerization GO:0051258 4 0.016
cellular protein metabolic process GO:0044267 129 0.016
stem cell division GO:0017145 1 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
system process GO:0003008 185 0.016
sensory organ development GO:0007423 393 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
microtubule organizing center organization GO:0031023 1 0.016
cellular respiration GO:0045333 3 0.016
erk1 and erk2 cascade GO:0070371 4 0.015
establishment of localization GO:0051234 244 0.015
regulation of inflammatory response GO:0050727 2 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
germ line stem cell maintenance GO:0030718 2 0.015
positive regulation of immune effector process GO:0002699 3 0.015
regulation of autophagy GO:0010506 3 0.015
developmental growth GO:0048589 166 0.015
locomotion GO:0040011 313 0.015
female sex differentiation GO:0046660 4 0.015
macromolecule modification GO:0043412 111 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
endosomal transport GO:0016197 2 0.015
response to organic substance GO:0010033 153 0.015
regulation of blood pressure GO:0008217 1 0.015
cell migration GO:0016477 237 0.015
tube morphogenesis GO:0035239 349 0.015
membrane invagination GO:0010324 1 0.015
generation of neurons GO:0048699 385 0.015
macromolecular complex disassembly GO:0032984 1 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
single fertilization GO:0007338 3 0.015
single organism organelle organization GO:1902589 199 0.015
cognition GO:0050890 1 0.015
protein complex disassembly GO:0043241 1 0.015
interspecies interaction between organisms GO:0044419 4 0.015
double strand break repair GO:0006302 3 0.015
positive regulation of dna metabolic process GO:0051054 1 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
response to topologically incorrect protein GO:0035966 2 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
dna templated transcription elongation GO:0006354 3 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
compound eye development GO:0048749 2 0.014
negative regulation of catabolic process GO:0009895 3 0.014
neuron differentiation GO:0030182 353 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
homeostatic process GO:0042592 142 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
exocytosis GO:0006887 1 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
protein polyubiquitination GO:0000209 4 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
Human
lymphocyte proliferation GO:0046651 1 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
glucose homeostasis GO:0042593 1 0.014
cellular response to radiation GO:0071478 4 0.014
rna localization GO:0006403 4 0.014
spermatid differentiation GO:0048515 2 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
single organism localization GO:1902578 225 0.014
eye development GO:0001654 277 0.014
cell projection morphogenesis GO:0048858 244 0.014
female gonad development GO:0008585 4 0.013
vasculature development GO:0001944 278 0.013
centrosome organization GO:0051297 1 0.013
localization of cell GO:0051674 244 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
positive regulation of secretion GO:0051047 1 0.013
embryonic organ development GO:0048568 381 0.013
regionalization GO:0003002 274 0.013
cell motility GO:0048870 244 0.013
neuroblast proliferation GO:0007405 2 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of reproductive process GO:2000241 4 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
antimicrobial humoral response GO:0019730 2 0.013
cell part morphogenesis GO:0032990 246 0.013
response to external stimulus GO:0009605 264 0.013
nuclear export GO:0051168 1 0.013
cell death GO:0008219 121 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
cellular response to organic substance GO:0071310 105 0.013
viral process GO:0016032 1 0.013
cellular protein modification process GO:0006464 100 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
spermatid development GO:0007286 2 0.013
negative regulation of nuclear division GO:0051784 3 0.013
fertilization GO:0009566 3 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
intracellular signal transduction GO:0035556 85 0.013
regulation of jak stat cascade GO:0046425 3 0.013
secondary metabolic process GO:0019748 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
multi organism cellular process GO:0044764 2 0.013
positive regulation of cellular process GO:0048522 201 0.013
cell projection organization GO:0030030 284 0.013
blood vessel development GO:0001568 246 0.012
digestive tract development GO:0048565 265 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of organelle assembly GO:1902115 4 0.012
regulation of metal ion transport GO:0010959 4 0.012
b cell activation GO:0042113 2 0.012
rna transport GO:0050658 2 0.012
response to carbohydrate GO:0009743 3 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
sequestering of metal ion GO:0051238 3 0.012
nucleic acid transport GO:0050657 2 0.012
regulation of protein polymerization GO:0032271 2 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
spindle assembly GO:0051225 2 0.012
head development GO:0060322 303 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
cell matrix adhesion GO:0007160 4 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
carbohydrate homeostasis GO:0033500 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
small molecule catabolic process GO:0044282 3 0.012
locomotor rhythm GO:0045475 3 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
protein modification process GO:0036211 100 0.012
regulation of muscle contraction GO:0006937 3 0.012
mitotic cytokinesis GO:0000281 3 0.012
vacuolar transport GO:0007034 2 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
heart development GO:0007507 313 0.012
establishment of rna localization GO:0051236 3 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
negative regulation of defense response GO:0031348 2 0.012
response to monosaccharide GO:0034284 3 0.012
negative regulation of protein transport GO:0051224 3 0.012
macroautophagy GO:0016236 1 0.012
rna modification GO:0009451 2 0.012
programmed cell death GO:0012501 119 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
brain development GO:0007420 293 0.012
single organism transport GO:0044765 206 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
activation of mapk activity GO:0000187 3 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
negative regulation of secretion GO:0051048 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
actin filament polymerization GO:0030041 2 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
apoptotic process GO:0006915 116 0.011
rna export from nucleus GO:0006405 1 0.011
peptidyl serine modification GO:0018209 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
camera type eye development GO:0043010 222 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
regulation of circadian rhythm GO:0042752 4 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
lamellipodium assembly GO:0030032 1 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
neuron development GO:0048666 262 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
multi organism process GO:0051704 134 0.011
alcohol biosynthetic process GO:0046165 2 0.011
chemosensory behavior GO:0007635 1 0.011
cell substrate adhesion GO:0031589 4 0.011
response to wounding GO:0009611 116 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
primary neural tube formation GO:0014020 1 0.011
sequestering of calcium ion GO:0051208 3 0.011
nucleobase containing compound transport GO:0015931 2 0.011
positive regulation of multi organism process GO:0043902 3 0.011
protein stabilization GO:0050821 2 0.011
recombinational repair GO:0000725 1 0.011
muscle structure development GO:0061061 196 0.011
regulation of synapse assembly GO:0051963 3 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
response to nutrient GO:0007584 3 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
regulation of cellular component organization GO:0051128 86 0.011
gastrulation GO:0007369 208 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
regulation of synapse organization GO:0050807 3 0.011
meiosis i GO:0007127 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
tube closure GO:0060606 1 0.011
mitochondrial transport GO:0006839 2 0.011
cell substrate junction assembly GO:0007044 2 0.010
glial cell migration GO:0008347 3 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
peptide transport GO:0015833 1 0.010
blood vessel morphogenesis GO:0048514 216 0.010
somatic muscle development GO:0007525 4 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
regulation of organ growth GO:0046620 3 0.010
translational initiation GO:0006413 3 0.010
lipid homeostasis GO:0055088 3 0.010
organelle assembly GO:0070925 110 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
positive regulation of metabolic process GO:0009893 108 0.010
negative regulation of multi organism process GO:0043901 3 0.010
digestive tract morphogenesis GO:0048546 231 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
somatic stem cell maintenance GO:0035019 1 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
positive regulation of chromatin modification GO:1903310 1 0.010
regulation of jun kinase activity GO:0043506 3 0.010
regulation of dna replication GO:0006275 3 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
angiogenesis GO:0001525 158 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
protein homooligomerization GO:0051260 3 0.010
protein heterooligomerization GO:0051291 1 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010

irf2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.020
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.013
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012