Danio rerio

0 known processes

serpina1l

serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like

(Aliases: zgc:136659,MGC136659,sb:cb301,cb301,wu:fb66d09)

serpina1l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to external stimulus GO:0071496 2 0.152
larval development GO:0002164 2 0.102
regulation of cellular metabolic process GO:0031323 320 0.086
aging GO:0007568 2 0.079
negative regulation of protein processing GO:0010955 10 0.079
response to stress GO:0006950 263 0.078
regulation of reactive oxygen species metabolic process GO:2000377 2 0.072
cellular protein catabolic process GO:0044257 4 0.071
positive regulation of transport GO:0051050 2 0.070
negative regulation of cellular process GO:0048523 283 0.069
sequestering of metal ion GO:0051238 3 0.060
single organism nuclear import GO:1902593 3 0.059
maintenance of location GO:0051235 4 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
coagulation GO:0050817 13 0.053
regulation of metal ion transport GO:0010959 4 0.052
regulation of macromolecule metabolic process GO:0060255 317 0.052
regulation of metabolic process GO:0019222 359 0.051
gene expression GO:0010467 252 0.051
negative regulation of response to stimulus GO:0048585 104 0.051
signal transduction GO:0007165 455 0.051
negative regulation of biological process GO:0048519 304 0.050
regulation of establishment of protein localization GO:0070201 4 0.049
multicellular organismal metabolic process GO:0044236 2 0.049
regulation of wound healing GO:0061041 2 0.048
regulation of calcium ion transport GO:0051924 2 0.048
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.048
cell surface receptor signaling pathway GO:0007166 325 0.048
tissue remodeling GO:0048771 4 0.047
cellular response to extracellular stimulus GO:0031668 2 0.047
protein import GO:0017038 3 0.047
nucleocytoplasmic transport GO:0006913 4 0.047
digestive system development GO:0055123 289 0.046
establishment of protein localization to organelle GO:0072594 4 0.045
modification dependent macromolecule catabolic process GO:0043632 3 0.044
regulation of biological quality GO:0065008 263 0.044
tube morphogenesis GO:0035239 349 0.043
cellular macromolecule metabolic process GO:0044260 391 0.043
regulation of response to stimulus GO:0048583 269 0.043
positive regulation of cellular process GO:0048522 201 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.041
transport GO:0006810 220 0.041
morphogenesis of an epithelium GO:0002009 333 0.041
meiotic nuclear division GO:0007126 4 0.041
cellular response to nutrient levels GO:0031669 2 0.040
modification dependent protein catabolic process GO:0019941 3 0.040
regulation of cytoplasmic transport GO:1903649 4 0.039
negative regulation of sequestering of calcium ion GO:0051283 4 0.039
regulation of glial cell differentiation GO:0045685 4 0.039
collagen metabolic process GO:0032963 2 0.038
regulation of sequestering of calcium ion GO:0051282 4 0.037
negative regulation of nuclear division GO:0051784 3 0.037
locomotion GO:0040011 313 0.036
cellular component movement GO:0006928 335 0.036
proteasomal protein catabolic process GO:0010498 2 0.036
positive regulation of cellular component biogenesis GO:0044089 3 0.036
regulation of cytokine production GO:0001817 3 0.035
cell migration GO:0016477 237 0.035
release of sequestered calcium ion into cytosol GO:0051209 3 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
digestive tract development GO:0048565 265 0.035
rna localization GO:0006403 4 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
protein localization to nucleus GO:0034504 3 0.035
nuclear transport GO:0051169 4 0.034
regulation of multicellular organismal development GO:2000026 223 0.034
regulation of protein transport GO:0051223 3 0.033
regulation of meiotic cell cycle GO:0051445 1 0.033
regulation of synapse organization GO:0050807 3 0.033
protein import into nucleus GO:0006606 3 0.032
protein metabolic process GO:0019538 183 0.032
cellular response to estrogen stimulus GO:0071391 24 0.032
regulation of protein catabolic process GO:0042176 1 0.031
astrocyte differentiation GO:0048708 1 0.031
cell motility GO:0048870 244 0.031
regulation of intracellular protein transport GO:0033157 3 0.031
nuclear import GO:0051170 3 0.031
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.031
hepaticobiliary system development GO:0061008 98 0.030
transcription dna templated GO:0006351 181 0.030
regulation of cell shape GO:0008360 1 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
single organism metabolic process GO:0044710 217 0.030
lipid storage GO:0019915 1 0.029
response to wounding GO:0009611 116 0.029
cell substrate adhesion GO:0031589 4 0.029
regulation of blood coagulation GO:0030193 1 0.029
regulation of gene expression GO:0010468 265 0.029
guanosine containing compound metabolic process GO:1901068 4 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
regulation of primary metabolic process GO:0080090 311 0.028
liver development GO:0001889 96 0.028
negative regulation of cytoplasmic transport GO:1903650 2 0.028
positive regulation of cell cycle GO:0045787 3 0.028
female gonad development GO:0008585 4 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
positive regulation of cytokine production GO:0001819 2 0.027
erk1 and erk2 cascade GO:0070371 4 0.027
proteolysis GO:0006508 38 0.027
positive regulation of biological process GO:0048518 253 0.027
response to carbohydrate GO:0009743 3 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.026
cellular ketone metabolic process GO:0042180 11 0.026
g1 s transition of mitotic cell cycle GO:0000082 1 0.026
phagocytosis GO:0006909 3 0.026
negative regulation of chromosome organization GO:2001251 1 0.026
response to chemical GO:0042221 320 0.026
ion transport GO:0006811 114 0.026
wound healing GO:0042060 90 0.026
cellular response to starvation GO:0009267 1 0.026
response to organic substance GO:0010033 153 0.026
gland development GO:0048732 143 0.026
negative regulation of cellular catabolic process GO:0031330 3 0.026
spindle assembly GO:0051225 2 0.026
positive regulation of catabolic process GO:0009896 4 0.026
heterocycle metabolic process GO:0046483 290 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
regulation of multicellular organismal metabolic process GO:0044246 2 0.025
regulation of protein localization to nucleus GO:1900180 2 0.025
inositol lipid mediated signaling GO:0048017 2 0.025
cellular component disassembly GO:0022411 1 0.025
negative regulation of catabolic process GO:0009895 3 0.025
immune system process GO:0002376 241 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
negative regulation of proteolysis GO:0045861 10 0.024
phosphatidylinositol mediated signaling GO:0048015 2 0.024
biosynthetic process GO:0009058 294 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
establishment of localization GO:0051234 244 0.024
cell cycle g1 s phase transition GO:0044843 1 0.024
peptidyl serine phosphorylation GO:0018105 1 0.024
regulation of inflammatory response GO:0050727 2 0.024
regulation of protein targeting GO:1903533 2 0.024
cellular response to organic cyclic compound GO:0071407 38 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
embryonic skeletal system development GO:0048706 97 0.023
negative regulation of metabolic process GO:0009892 86 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
single organism transport GO:0044765 206 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
collagen biosynthetic process GO:0032964 2 0.023
cell morphogenesis GO:0000902 289 0.023
inner ear development GO:0048839 126 0.022
protein targeting to nucleus GO:0044744 3 0.022
nucleic acid templated transcription GO:0097659 181 0.022
homeostatic process GO:0042592 142 0.022
single organism localization GO:1902578 225 0.022
organic substance biosynthetic process GO:1901576 289 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
establishment of rna localization GO:0051236 3 0.021
cellular amine metabolic process GO:0044106 2 0.021
regulation of hemostasis GO:1900046 1 0.021
intracellular signal transduction GO:0035556 85 0.021
regulation of protein complex assembly GO:0043254 3 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
localization of cell GO:0051674 244 0.021
rna metabolic process GO:0016070 219 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
blood coagulation GO:0007596 12 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
positive regulation of secretion GO:0051047 1 0.021
chordate embryonic development GO:0043009 271 0.021
cellular component morphogenesis GO:0032989 336 0.020
regulation of signal transduction GO:0009966 225 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
regulation of blood vessel size GO:0050880 2 0.020
protein secretion GO:0009306 1 0.020
negative regulation of signal transduction GO:0009968 94 0.020
ear development GO:0043583 127 0.020
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.020
female sex differentiation GO:0046660 4 0.020
peptide transport GO:0015833 1 0.020
negative regulation of signaling GO:0023057 96 0.020
ovulation cycle process GO:0022602 2 0.020
mitotic dna damage checkpoint GO:0044773 4 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
mitotic dna integrity checkpoint GO:0044774 4 0.019
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.019
negative regulation of defense response GO:0031348 2 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
peptidyl serine modification GO:0018209 2 0.019
positive regulation of cell adhesion GO:0045785 1 0.019
response to monosaccharide GO:0034284 3 0.019
nucleic acid metabolic process GO:0090304 244 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
cellular response to lipid GO:0071396 39 0.019
negative regulation of gene expression GO:0010629 65 0.019
protein polymerization GO:0051258 4 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
sensory organ development GO:0007423 393 0.019
fertilization GO:0009566 3 0.019
ovulation cycle GO:0042698 2 0.018
response to glucose GO:0009749 3 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
negative regulation of protein maturation GO:1903318 10 0.018
amine metabolic process GO:0009308 2 0.018
programmed cell death GO:0012501 119 0.018
regulation of tube size GO:0035150 2 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of biosynthetic process GO:0009889 250 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
antimicrobial humoral response GO:0019730 2 0.018
heart development GO:0007507 313 0.018
system process GO:0003008 185 0.018
cell matrix adhesion GO:0007160 4 0.018
rna transport GO:0050658 2 0.018
cellular response to steroid hormone stimulus GO:0071383 31 0.018
cellular protein metabolic process GO:0044267 129 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
nucleic acid transport GO:0050657 2 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
negative regulation of mitosis GO:0045839 3 0.017
regulation of developmental process GO:0050793 247 0.017
determination of bilateral symmetry GO:0009855 204 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of cell communication GO:0010646 232 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
response to steroid hormone GO:0048545 35 0.017
cellular localization GO:0051641 97 0.017
cellular response to organic substance GO:0071310 105 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
single organism organelle organization GO:1902589 199 0.016
regulation of localization GO:0032879 104 0.016
protein modification process GO:0036211 100 0.016
calcium ion transport into cytosol GO:0060402 3 0.016
glucose homeostasis GO:0042593 1 0.016
ameboidal type cell migration GO:0001667 143 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
embryonic organ development GO:0048568 381 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of cell projection assembly GO:0060491 4 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
positive regulation of metabolic process GO:0009893 108 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
leukocyte proliferation GO:0070661 1 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
mitochondrion organization GO:0007005 4 0.016
cytosolic calcium ion transport GO:0060401 3 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
b cell activation GO:0042113 2 0.016
positive regulation of wound healing GO:0090303 1 0.016
negative regulation of protein transport GO:0051224 3 0.016
gtp metabolic process GO:0046039 4 0.016
response to abiotic stimulus GO:0009628 122 0.015
regulation of hormone secretion GO:0046883 2 0.015
stem cell maintenance GO:0019827 4 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
positive regulation of blood circulation GO:1903524 2 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
nuclear export GO:0051168 1 0.015
double strand break repair GO:0006302 3 0.015
stem cell division GO:0017145 1 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
glial cell differentiation GO:0010001 42 0.015
apoptotic process GO:0006915 116 0.015
regulation of synapse assembly GO:0051963 3 0.015
regulation of exocytosis GO:0017157 1 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
sensory organ morphogenesis GO:0090596 200 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
organelle organization GO:0006996 227 0.015
mitochondrial transport GO:0006839 2 0.015
regulation of dna replication GO:0006275 3 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
nucleobase containing compound transport GO:0015931 2 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
regeneration GO:0031099 91 0.014
regulation of cell activation GO:0050865 1 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
regulation of signaling GO:0023051 235 0.014
membrane fusion GO:0061025 2 0.014
rna biosynthetic process GO:0032774 181 0.014
negative regulation of kinase activity GO:0033673 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
regulation of cellular component organization GO:0051128 86 0.014
cellular component assembly GO:0022607 170 0.014
developmental growth GO:0048589 166 0.014
negative regulation of cytokine production GO:0001818 1 0.014
fat soluble vitamin metabolic process GO:0006775 4 0.014
cellular component biogenesis GO:0044085 178 0.014
gastrulation GO:0007369 208 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
camera type eye development GO:0043010 222 0.014
peptide metabolic process GO:0006518 1 0.014
macromolecule modification GO:0043412 111 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
lymphocyte proliferation GO:0046651 1 0.014
membrane invagination GO:0010324 1 0.014
immune system development GO:0002520 191 0.014
mesenchymal cell differentiation GO:0048762 87 0.013
reactive oxygen species metabolic process GO:0072593 6 0.013
cell growth GO:0016049 57 0.013
response to hexose GO:0009746 3 0.013
brain development GO:0007420 293 0.013
response to external stimulus GO:0009605 264 0.013
regulation of cell proliferation GO:0042127 37 0.013
growth GO:0040007 174 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
autophagy GO:0006914 4 0.013
multicellular organism growth GO:0035264 4 0.013
regulation of gtpase activity GO:0043087 2 0.013
neuroblast proliferation GO:0007405 2 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
regulation of programmed cell death GO:0043067 101 0.013
central nervous system development GO:0007417 387 0.013
neurotransmitter secretion GO:0007269 2 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
response to lipid GO:0033993 60 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
chemical homeostasis GO:0048878 49 0.013
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.013
regulation of nervous system development GO:0051960 90 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
regulation of protein maturation GO:1903317 10 0.013
regulation of protein metabolic process GO:0051246 56 0.013
muscle structure development GO:0061061 196 0.013
regulation of chromosome segregation GO:0051983 1 0.013
positive regulation of cell division GO:0051781 2 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
cytokinesis GO:0000910 3 0.012
exocytosis GO:0006887 1 0.012
superoxide metabolic process GO:0006801 2 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
digestive tract morphogenesis GO:0048546 231 0.012
phagocytosis engulfment GO:0006911 1 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
positive regulation of cell activation GO:0050867 1 0.012
generation of neurons GO:0048699 385 0.012
cell proliferation GO:0008283 80 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
skeletal system development GO:0001501 181 0.012
regulation of bone remodeling GO:0046850 2 0.012
organic acid metabolic process GO:0006082 31 0.012
post embryonic morphogenesis GO:0009886 4 0.012
eye development GO:0001654 277 0.012
regulation of transcription dna templated GO:0006355 213 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
cell cycle arrest GO:0007050 1 0.012
meiotic cell cycle process GO:1903046 3 0.012
rna export from nucleus GO:0006405 1 0.012
hormone transport GO:0009914 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
establishment of localization in cell GO:0051649 77 0.012
mononuclear cell proliferation GO:0032943 1 0.012
multicellular organismal response to stress GO:0033555 2 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
hormone secretion GO:0046879 2 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
protein processing GO:0016485 12 0.011
interspecies interaction between organisms GO:0044419 4 0.011
carbohydrate homeostasis GO:0033500 1 0.011
blood vessel development GO:0001568 246 0.011
cell death GO:0008219 121 0.011
vasculature development GO:0001944 278 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
cation transport GO:0006812 81 0.011
regulation of binding GO:0051098 3 0.011
stem cell development GO:0048864 82 0.011
tissue regeneration GO:0042246 74 0.011
stem cell differentiation GO:0048863 117 0.011
cellular response to hypoxia GO:0071456 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
zymogen activation GO:0031638 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
regulation of cell motility GO:2000145 46 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
negative regulation of cell communication GO:0010648 96 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
protein complex disassembly GO:0043241 1 0.011
single organism biosynthetic process GO:0044711 71 0.011
adult behavior GO:0030534 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.010
death GO:0016265 121 0.010
regulation of response to stress GO:0080134 36 0.010
extracellular structure organization GO:0043062 27 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
regulation of neurogenesis GO:0050767 87 0.010
lipid oxidation GO:0034440 1 0.010
cognition GO:0050890 1 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
synaptic transmission cholinergic GO:0007271 4 0.010
regulation of cellular component movement GO:0051270 55 0.010
protein acetylation GO:0006473 2 0.010
response to other organism GO:0051707 97 0.010
regulation of cell differentiation GO:0045595 142 0.010
head development GO:0060322 303 0.010
rna 3 end processing GO:0031123 2 0.010
negative regulation of cell cycle GO:0045786 14 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
spindle assembly involved in mitosis GO:0090307 1 0.010
specification of symmetry GO:0009799 204 0.010

serpina1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.075
disease of anatomical entity DOID:7 0 0.075
hematopoietic system disease DOID:74 0 0.075
disease of metabolism DOID:0014667 0 0.021
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.018
cardiovascular system disease DOID:1287 0 0.017
inherited metabolic disorder DOID:655 0 0.015
bone marrow disease DOID:4961 0 0.014