Danio rerio

0 known processes

sh3pxd2b

SH3 and PX domains 2B

(Aliases: im:7155315)

sh3pxd2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.142
regulation of developmental process GO:0050793 247 0.121
Mouse
signal transduction GO:0007165 455 0.091
regulation of multicellular organism growth GO:0040014 4 0.090
morphogenesis of an epithelium GO:0002009 333 0.081
regulation of protein complex assembly GO:0043254 3 0.063
cellular macromolecule metabolic process GO:0044260 391 0.063
nucleic acid templated transcription GO:0097659 181 0.063
multicellular organism growth GO:0035264 4 0.058
organic substance biosynthetic process GO:1901576 289 0.055
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.054
regulation of signal transduction GO:0009966 225 0.053
organic cyclic compound metabolic process GO:1901360 301 0.051
regulation of stem cell differentiation GO:2000736 4 0.051
regulation of response to stimulus GO:0048583 269 0.050
aging GO:0007568 2 0.050
protein metabolic process GO:0019538 183 0.049
cell surface receptor signaling pathway GO:0007166 325 0.048
central nervous system development GO:0007417 387 0.048
heterocycle metabolic process GO:0046483 290 0.048
organic acid metabolic process GO:0006082 31 0.047
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.047
regulation of multicellular organismal development GO:2000026 223 0.046
heart development GO:0007507 313 0.045
Human Mouse
rna biosynthetic process GO:0032774 181 0.045
positive regulation of cellular component biogenesis GO:0044089 3 0.044
regulation of protein transport GO:0051223 3 0.044
negative regulation of ras protein signal transduction GO:0046580 1 0.043
response to external stimulus GO:0009605 264 0.042
Zebrafish
tube morphogenesis GO:0035239 349 0.041
maintenance of location GO:0051235 4 0.040
cellular protein catabolic process GO:0044257 4 0.040
localization of cell GO:0051674 244 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.039
cellular macromolecule biosynthetic process GO:0034645 224 0.039
lipid storage GO:0019915 1 0.038
regulation of cell communication GO:0010646 232 0.038
negative regulation of biological process GO:0048519 304 0.038
modification dependent protein catabolic process GO:0019941 3 0.037
phagocytosis GO:0006909 3 0.037
regulation of multicellular organismal process GO:0051239 277 0.037
gene expression GO:0010467 252 0.036
regulation of biosynthetic process GO:0009889 250 0.036
determination of left right symmetry GO:0007368 179 0.036
regulation of reproductive process GO:2000241 4 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
chordate embryonic development GO:0043009 271 0.035
tube closure GO:0060606 1 0.035
primary neural tube formation GO:0014020 1 0.035
rna metabolic process GO:0016070 219 0.035
camera type eye development GO:0043010 222 0.035
aromatic compound biosynthetic process GO:0019438 217 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.034
regulation of transcription dna templated GO:0006355 213 0.033
programmed cell death GO:0012501 119 0.033
sensory organ development GO:0007423 393 0.033
Human Mouse
regulation of signaling GO:0023051 235 0.033
response to organic substance GO:0010033 153 0.033
immune system process GO:0002376 241 0.033
axon development GO:0061564 166 0.033
biosynthetic process GO:0009058 294 0.033
cellular component assembly GO:0022607 170 0.032
Mouse
digestive tract development GO:0048565 265 0.032
positive regulation of catabolic process GO:0009896 4 0.032
positive regulation of signaling GO:0023056 56 0.032
nitrogen compound metabolic process GO:0006807 319 0.032
embryonic organ development GO:0048568 381 0.032
cellular amino acid metabolic process GO:0006520 7 0.032
positive regulation of cell cycle GO:0045787 3 0.032
tube formation GO:0035148 25 0.031
gland development GO:0048732 143 0.031
regulation of gene expression GO:0010468 265 0.031
nucleocytoplasmic transport GO:0006913 4 0.031
heterocycle biosynthetic process GO:0018130 215 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
nucleic acid metabolic process GO:0090304 244 0.031
oxoacid metabolic process GO:0043436 31 0.030
regulation of cellular biosynthetic process GO:0031326 245 0.030
cell death GO:0008219 121 0.030
developmental growth GO:0048589 166 0.030
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
cell projection organization GO:0030030 284 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
carboxylic acid metabolic process GO:0019752 22 0.029
generation of neurons GO:0048699 385 0.029
small molecule metabolic process GO:0044281 77 0.029
eye development GO:0001654 277 0.029
Human Mouse
positive regulation of cell adhesion GO:0045785 1 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.028
cellular component biogenesis GO:0044085 178 0.028
Mouse
negative regulation of cellular process GO:0048523 283 0.027
positive regulation of transport GO:0051050 2 0.027
nuclear transport GO:0051169 4 0.027
cognition GO:0050890 1 0.027
regulation of nucleic acid templated transcription GO:1903506 213 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
regulation of metabolic process GO:0019222 359 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
locomotion GO:0040011 313 0.026
connective tissue development GO:0061448 99 0.025
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
cell motility GO:0048870 244 0.024
growth GO:0040007 174 0.024
regulation of protein catabolic process GO:0042176 1 0.024
cell migration GO:0016477 237 0.024
positive regulation of transcription dna templated GO:0045893 57 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
stem cell maintenance GO:0019827 4 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
regulation of cellular component organization GO:0051128 86 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
cell substrate adhesion GO:0031589 4 0.023
regulation of binding GO:0051098 3 0.023
specification of symmetry GO:0009799 204 0.023
regulation of metal ion transport GO:0010959 4 0.023
macromolecule biosynthetic process GO:0009059 227 0.022
positive regulation of cellular process GO:0048522 201 0.022
Mouse
determination of bilateral symmetry GO:0009855 204 0.022
positive regulation of protein complex assembly GO:0031334 2 0.022
digestive system development GO:0055123 289 0.022
regulation of cell development GO:0060284 100 0.022
protein polymerization GO:0051258 4 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
response to lipid GO:0033993 60 0.021
head development GO:0060322 303 0.021
brain development GO:0007420 293 0.021
sensory organ morphogenesis GO:0090596 200 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
wnt signaling pathway GO:0016055 80 0.021
response to chemical GO:0042221 320 0.021
cellular protein modification process GO:0006464 100 0.021
urogenital system development GO:0001655 97 0.021
establishment of localization GO:0051234 244 0.021
regulation of synapse assembly GO:0051963 3 0.021
positive regulation of rna biosynthetic process GO:1902680 57 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
amine metabolic process GO:0009308 2 0.021
regulation of cytokine production GO:0001817 3 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
single organism metabolic process GO:0044710 217 0.021
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.020
regulation of cell activation GO:0050865 1 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.020
liver development GO:0001889 96 0.020
neuron differentiation GO:0030182 353 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
regulation of biological quality GO:0065008 263 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
ear development GO:0043583 127 0.020
response to stress GO:0006950 263 0.019
Zebrafish
response to organic cyclic compound GO:0014070 51 0.019
regulation of rna metabolic process GO:0051252 224 0.019
regulation of nervous system development GO:0051960 90 0.019
intracellular signal transduction GO:0035556 85 0.019
skeletal system morphogenesis GO:0048705 102 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
protein modification process GO:0036211 100 0.019
cell morphogenesis GO:0000902 289 0.019
cellular response to oxygen levels GO:0071453 1 0.019
steroid hormone mediated signaling pathway GO:0043401 9 0.019
negative regulation of cell communication GO:0010648 96 0.019
muscle tissue development GO:0060537 110 0.019
protein localization to nucleus GO:0034504 3 0.018
negative regulation of cytokine production GO:0001818 1 0.018
cellular amine metabolic process GO:0044106 2 0.018
transcription dna templated GO:0006351 181 0.018
immune system development GO:0002520 191 0.018
response to corticosteroid GO:0031960 1 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
protein import GO:0017038 3 0.018
digestive tract morphogenesis GO:0048546 231 0.018
negative regulation of signal transduction GO:0009968 94 0.018
regulation of canonical wnt signaling pathway GO:0060828 34 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
cellular protein metabolic process GO:0044267 129 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
cellular ketone metabolic process GO:0042180 11 0.017
positive regulation of multicellular organismal process GO:0051240 52 0.017
cellular biosynthetic process GO:0044249 286 0.017
eye morphogenesis GO:0048592 144 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of growth GO:0040008 42 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
death GO:0016265 121 0.016
cellular response to organic substance GO:0071310 105 0.016
hindbrain development GO:0030902 91 0.016
positive regulation of reproductive process GO:2000243 2 0.016
regulation of apoptotic process GO:0042981 98 0.016
positive regulation of biological process GO:0048518 253 0.016
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
regulation of calcium ion transport GO:0051924 2 0.016
regulation of epithelial to mesenchymal transition GO:0010717 3 0.016
macromolecule modification GO:0043412 111 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
multicellular organismal macromolecule metabolic process GO:0044259 2 0.016
regulation of dendrite development GO:0050773 3 0.016
post embryonic organ development GO:0048569 4 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
cellular modified amino acid metabolic process GO:0006575 3 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.015
negative chemotaxis GO:0050919 1 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
multicellular organismal metabolic process GO:0044236 2 0.015
single organism biosynthetic process GO:0044711 71 0.015
regulation of cell shape GO:0008360 1 0.015
cellular component movement GO:0006928 335 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
kidney development GO:0001822 92 0.015
hemopoiesis GO:0030097 183 0.015
muscle cell differentiation GO:0042692 139 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
peptide transport GO:0015833 1 0.015
regulation of inflammatory response GO:0050727 2 0.015
striated muscle cell development GO:0055002 108 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
autophagy GO:0006914 4 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
response to endogenous stimulus GO:0009719 83 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
meiotic nuclear division GO:0007126 4 0.014
system process GO:0003008 185 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
gtp catabolic process GO:0006184 2 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
nuclear import GO:0051170 3 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
protein import into nucleus GO:0006606 3 0.014
regulation of primary metabolic process GO:0080090 311 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
positive regulation of rna metabolic process GO:0051254 59 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
muscle structure development GO:0061061 196 0.014
regulation of cell differentiation GO:0045595 142 0.014
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
homeostatic process GO:0042592 142 0.014
response to nutrient GO:0007584 3 0.014
cellular component morphogenesis GO:0032989 336 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
negative regulation of defense response GO:0031348 2 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
protein targeting to nucleus GO:0044744 3 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
positive regulation of secretion GO:0051047 1 0.013
vasculature development GO:0001944 278 0.013
regulation of filopodium assembly GO:0051489 2 0.013
muscle cell development GO:0055001 115 0.013
apoptotic process GO:0006915 116 0.013
regulation of chondrocyte differentiation GO:0032330 1 0.013
protein secretion GO:0009306 1 0.013
regulation of wnt signaling pathway GO:0030111 53 0.013
negative regulation of signaling GO:0023057 96 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
regulation of protein binding GO:0043393 3 0.013
regionalization GO:0003002 274 0.013
regulation of cellular component movement GO:0051270 55 0.013
membrane invagination GO:0010324 1 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
establishment of blood brain barrier GO:0060856 2 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
transport GO:0006810 220 0.013
carbohydrate homeostasis GO:0033500 1 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
protein acetylation GO:0006473 2 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.012
regulation of chromosome segregation GO:0051983 1 0.012
cell cycle arrest GO:0007050 1 0.012
gtp metabolic process GO:0046039 4 0.012
gastrulation GO:0007369 208 0.012
activation of mapk activity GO:0000187 3 0.012
macromolecular complex assembly GO:0065003 35 0.012
Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
epiboly GO:0090504 41 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
regulation of cell death GO:0010941 103 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
phagocytosis engulfment GO:0006911 1 0.012
regulation of organelle assembly GO:1902115 4 0.012
cellular response to external stimulus GO:0071496 2 0.012
cell projection morphogenesis GO:0048858 244 0.012
ameboidal type cell migration GO:0001667 143 0.012
regulation of blood vessel size GO:0050880 2 0.012
inner ear development GO:0048839 126 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
lymphocyte proliferation GO:0046651 1 0.012
protein acylation GO:0043543 3 0.012
protein complex biogenesis GO:0070271 30 0.012
Mouse
cell part morphogenesis GO:0032990 246 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
regulation of response to stress GO:0080134 36 0.012
adult behavior GO:0030534 2 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.011
camera type eye morphogenesis GO:0048593 108 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
cellular response to hypoxia GO:0071456 1 0.011
positive regulation of developmental process GO:0051094 50 0.011
Mouse
positive regulation of metabolic process GO:0009893 108 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
Mouse
heart morphogenesis GO:0003007 156 0.011
compound eye development GO:0048749 2 0.011
protein complex assembly GO:0006461 30 0.011
Mouse
erk1 and erk2 cascade GO:0070371 4 0.011
regulation of protein targeting GO:1903533 2 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
regulation of gtpase activity GO:0043087 2 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
b cell activation GO:0042113 2 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
glucose homeostasis GO:0042593 1 0.011
renal tubule morphogenesis GO:0061333 1 0.011
collagen metabolic process GO:0032963 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
pancreas development GO:0031016 84 0.011
convergent extension GO:0060026 118 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
response to alkaloid GO:0043279 2 0.011
negative regulation of cell death GO:0060548 60 0.011
regulation of rho protein signal transduction GO:0035023 2 0.010
regeneration GO:0031099 91 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
cellular response to growth factor stimulus GO:0071363 39 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
cellular response to nutrient levels GO:0031669 2 0.010
cilium morphogenesis GO:0060271 85 0.010
stem cell division GO:0017145 1 0.010
regulation of cellular metabolic process GO:0031323 320 0.010
stem cell proliferation GO:0072089 4 0.010
response to wounding GO:0009611 116 0.010
multi organism process GO:0051704 134 0.010
Zebrafish

sh3pxd2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015