Danio rerio

12 known processes

aqp4

aquaporin 4

(Aliases: si:ch211-192k9.1,zgc:100922)

aqp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
water transport GO:0006833 15 0.493
fluid transport GO:0042044 17 0.293
urea transmembrane transport GO:0071918 9 0.246
Zebrafish
aging GO:0007568 2 0.232
ion transmembrane transport GO:0034220 91 0.222
Zebrafish
one carbon compound transport GO:0019755 14 0.191
Zebrafish Rat
glycerol transport GO:0015793 7 0.182
polyol transport GO:0015791 7 0.136
sensory organ development GO:0007423 393 0.113
Zebrafish
transport GO:0006810 220 0.112
single organism transport GO:0044765 206 0.108
inorganic anion transport GO:0015698 25 0.108
Zebrafish
eye development GO:0001654 277 0.106
Zebrafish
ion transport GO:0006811 114 0.103
Zebrafish
urea transport GO:0015840 11 0.102
Zebrafish
carbohydrate transport GO:0008643 13 0.087
larval development GO:0002164 2 0.082
camera type eye development GO:0043010 222 0.079
Zebrafish
ammonium transmembrane transport GO:0072488 2 0.075
Zebrafish
establishment of localization GO:0051234 244 0.068
anion transport GO:0006820 38 0.065
Zebrafish
transmembrane transport GO:0055085 120 0.064
monovalent inorganic cation transport GO:0015672 42 0.055
Zebrafish
head development GO:0060322 303 0.055
response to chemical GO:0042221 320 0.051
Rat
defense response to other organism GO:0098542 33 0.049
maintenance of location GO:0051235 4 0.046
regulation of metal ion transport GO:0010959 4 0.045
signal transduction GO:0007165 455 0.044
immune system process GO:0002376 241 0.044
establishment of endothelial barrier GO:0061028 3 0.044
defense response to bacterium GO:0042742 22 0.043
positive regulation of cell cycle GO:0045787 3 0.043
morphogenesis of an epithelium GO:0002009 333 0.040
heterocycle biosynthetic process GO:0018130 215 0.040
carbon dioxide transmembrane transport GO:0035378 1 0.039
Zebrafish
phagocytosis GO:0006909 3 0.037
response to external stimulus GO:0009605 264 0.035
brain development GO:0007420 293 0.034
g protein coupled receptor signaling pathway GO:0007186 74 0.033
stem cell proliferation GO:0072089 4 0.033
chordate embryonic development GO:0043009 271 0.033
cellular macromolecule metabolic process GO:0044260 391 0.033
multi organism process GO:0051704 134 0.032
Yeast Rat
stem cell maintenance GO:0019827 4 0.032
single organism localization GO:1902578 225 0.032
heterocycle metabolic process GO:0046483 290 0.030
organelle organization GO:0006996 227 0.029
rna metabolic process GO:0016070 219 0.029
vasculature development GO:0001944 278 0.029
lipid storage GO:0019915 1 0.029
tube morphogenesis GO:0035239 349 0.028
response to organic substance GO:0010033 153 0.028
Rat
endosome organization GO:0007032 2 0.027
positive regulation of transport GO:0051050 2 0.027
adult behavior GO:0030534 2 0.027
regulation of binding GO:0051098 3 0.027
ear development GO:0043583 127 0.027
gas transport GO:0015669 3 0.026
Zebrafish Rat
regionalization GO:0003002 274 0.026
cellular response to chemical stimulus GO:0070887 157 0.025
Rat
organic substance transport GO:0071702 58 0.025
Zebrafish Rat
regulation of metabolic process GO:0019222 359 0.024
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
positive regulation of biological process GO:0048518 253 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
somite development GO:0061053 96 0.023
central nervous system development GO:0007417 387 0.023
sensory organ morphogenesis GO:0090596 200 0.023
organic substance biosynthetic process GO:1901576 289 0.023
lipid catabolic process GO:0016042 4 0.023
carbon dioxide transport GO:0015670 3 0.023
Zebrafish Rat
regulation of response to stimulus GO:0048583 269 0.023
defense response to gram negative bacterium GO:0050829 8 0.023
neuron differentiation GO:0030182 353 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
generation of neurons GO:0048699 385 0.022
homeostatic process GO:0042592 142 0.022
Mouse Rat
anterior posterior pattern specification GO:0009952 152 0.022
inorganic ion transmembrane transport GO:0098660 57 0.022
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.022
phagocytosis engulfment GO:0006911 1 0.022
regulation of primary metabolic process GO:0080090 311 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
nitrogen compound transport GO:0071705 23 0.021
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.021
locomotion GO:0040011 313 0.021
negative regulation of biological process GO:0048519 304 0.021
Rat
neuromast development GO:0048884 46 0.021
hormone secretion GO:0046879 2 0.021
determination of left right symmetry GO:0007368 179 0.021
inner ear development GO:0048839 126 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
cellular component movement GO:0006928 335 0.021
eye morphogenesis GO:0048592 144 0.021
embryonic organ development GO:0048568 381 0.021
inorganic cation transmembrane transport GO:0098662 50 0.021
Zebrafish
organic hydroxy compound transport GO:0015850 14 0.021
cellular protein catabolic process GO:0044257 4 0.020
regulation of sodium ion transport GO:0002028 2 0.020
regulation of biological quality GO:0065008 263 0.020
Mouse Rat
mitochondrion organization GO:0007005 4 0.020
cellular amine metabolic process GO:0044106 2 0.020
regulation of protein catabolic process GO:0042176 1 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
biosynthetic process GO:0009058 294 0.019
peptide transport GO:0015833 1 0.019
cell morphogenesis GO:0000902 289 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
cellular response to organic substance GO:0071310 105 0.019
Rat
regulation of cellular ph GO:0030641 1 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
hormone transport GO:0009914 2 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of signaling GO:0023051 235 0.019
cellular component biogenesis GO:0044085 178 0.019
Rat
response to vitamin GO:0033273 3 0.018
sensory system development GO:0048880 76 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
epithelial cell differentiation GO:0030855 116 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
regulation of protein binding GO:0043393 3 0.018
negative regulation of catabolic process GO:0009895 3 0.018
regulation of protein complex assembly GO:0043254 3 0.018
protein localization to nucleus GO:0034504 3 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
cellular component disassembly GO:0022411 1 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
long chain fatty acid metabolic process GO:0001676 1 0.018
positive regulation of stem cell proliferation GO:2000648 1 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
muscle cell development GO:0055001 115 0.018
gastrulation with mouth forming second GO:0001702 44 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
compound eye development GO:0048749 2 0.018
system process GO:0003008 185 0.018
Mouse
cellular response to nutrient levels GO:0031669 2 0.018
water homeostasis GO:0030104 4 0.018
Mouse
rna biosynthetic process GO:0032774 181 0.018
nuclear transport GO:0051169 4 0.017
organic acid catabolic process GO:0016054 3 0.017
response to topologically incorrect protein GO:0035966 2 0.017
multicellular organism growth GO:0035264 4 0.017
response to vitamin b3 GO:0033552 2 0.017
gtp metabolic process GO:0046039 4 0.017
retina development in camera type eye GO:0060041 146 0.017
small molecule catabolic process GO:0044282 3 0.017
membrane invagination GO:0010324 1 0.017
heart looping GO:0001947 94 0.017
protein polyubiquitination GO:0000209 4 0.017
somitogenesis GO:0001756 87 0.017
response to hexose GO:0009746 3 0.017
Rat
cellular response to starvation GO:0009267 1 0.017
cation transport GO:0006812 81 0.017
Zebrafish
synaptic vesicle transport GO:0048489 1 0.017
synaptic vesicle localization GO:0097479 1 0.017
positive regulation of secretion GO:0051047 1 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
digestive tract development GO:0048565 265 0.017
neurotransmitter secretion GO:0007269 2 0.017
amine metabolic process GO:0009308 2 0.017
cellular response to external stimulus GO:0071496 2 0.017
atp catabolic process GO:0006200 4 0.017
meiotic cell cycle process GO:1903046 3 0.016
Yeast
protein targeting to nucleus GO:0044744 3 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
response to biotic stimulus GO:0009607 97 0.016
gtp catabolic process GO:0006184 2 0.016
response to nutrient GO:0007584 3 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
lateral line development GO:0048882 66 0.016
response to monosaccharide GO:0034284 3 0.016
Rat
chemosensory behavior GO:0007635 1 0.016
response to carbohydrate GO:0009743 3 0.016
Rat
response to external biotic stimulus GO:0043207 97 0.016
nucleic acid metabolic process GO:0090304 244 0.016
response to alkaloid GO:0043279 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
embryonic heart tube development GO:0035050 133 0.016
regulation of ph GO:0006885 3 0.016
cellular component morphogenesis GO:0032989 336 0.016
morphogenesis of an epithelial sheet GO:0002011 49 0.016
positive regulation of neural precursor cell proliferation GO:2000179 1 0.016
protein acetylation GO:0006473 2 0.016
forebrain development GO:0030900 96 0.016
digestive system development GO:0055123 289 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
gene expression GO:0010467 252 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
meiotic nuclear division GO:0007126 4 0.015
lateral line system development GO:0048925 76 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
amide transport GO:0042886 12 0.015
Zebrafish
gastrulation GO:0007369 208 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
neuron development GO:0048666 262 0.015
regulation of gene expression GO:0010468 265 0.015
response to stress GO:0006950 263 0.015
Rat
cell surface receptor signaling pathway GO:0007166 325 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
heart development GO:0007507 313 0.015
single organism nuclear import GO:1902593 3 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of reproductive process GO:2000241 4 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
muscle structure development GO:0061061 196 0.015
neurotransmitter transport GO:0006836 2 0.015
lipid homeostasis GO:0055088 3 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
circadian sleep wake cycle GO:0042745 2 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
defense response GO:0006952 47 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
cell migration GO:0016477 237 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.014
somatic muscle development GO:0007525 4 0.014
response to other organism GO:0051707 97 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
nucleic acid templated transcription GO:0097659 181 0.014
stem cell division GO:0017145 1 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
striated muscle cell development GO:0055002 108 0.014
negative regulation of cellular process GO:0048523 283 0.014
Rat
regulation of multicellular organism growth GO:0040014 4 0.014
death GO:0016265 121 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
pericardium development GO:0060039 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
regulation of transporter activity GO:0032409 2 0.014
transcription dna templated GO:0006351 181 0.014
cell substrate adhesion GO:0031589 4 0.013
negative regulation of kinase activity GO:0033673 4 0.013
energy reserve metabolic process GO:0006112 2 0.013
startle response GO:0001964 4 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
single organism organelle organization GO:1902589 199 0.013
protein import GO:0017038 3 0.013
cellular component assembly GO:0022607 170 0.013
Rat
positive regulation of cytokine production GO:0001819 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
protein import into nucleus GO:0006606 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
regulation of cytokine production GO:0001817 3 0.013
Rat
rna localization GO:0006403 4 0.013
regulation of hormone secretion GO:0046883 2 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
regulation of signal transduction GO:0009966 225 0.013
cellular response to topologically incorrect protein GO:0035967 2 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of rna metabolic process GO:0051252 224 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
carboxylic acid catabolic process GO:0046395 3 0.013
protein localization to plasma membrane GO:0072659 1 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
cell matrix adhesion GO:0007160 4 0.013
cellular response to lipid GO:0071396 39 0.013
Rat
sensory perception of chemical stimulus GO:0007606 3 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
cellular biosynthetic process GO:0044249 286 0.013
dna templated transcription elongation GO:0006354 3 0.013
blood vessel development GO:0001568 246 0.013
determination of bilateral symmetry GO:0009855 204 0.013
response to bacterium GO:0009617 58 0.013
segmentation GO:0035282 97 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of protein targeting GO:1903533 2 0.012
response to glucocorticoid GO:0051384 1 0.012
Rat
positive regulation of blood circulation GO:1903524 2 0.012
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
renal absorption GO:0070293 1 0.012
Mouse
chemical homeostasis GO:0048878 49 0.012
Mouse Rat
transmission of nerve impulse GO:0019226 19 0.012
ph reduction GO:0045851 1 0.012
innate immune response GO:0045087 13 0.012
regulation of dendrite development GO:0050773 3 0.012
protein acylation GO:0043543 3 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
spermatid differentiation GO:0048515 2 0.012
cellular ketone metabolic process GO:0042180 11 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
exocytosis GO:0006887 1 0.012
epiboly GO:0090504 41 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of cell activation GO:0050865 1 0.012
ammonium transport GO:0015696 6 0.012
Zebrafish
regulation of tube size GO:0035150 2 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
organic acid metabolic process GO:0006082 31 0.011
regulation of intracellular ph GO:0051453 1 0.011
small molecule metabolic process GO:0044281 77 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of synapse organization GO:0050807 3 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
fatty acid transport GO:0015908 1 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
response to uv GO:0009411 3 0.011
urogenital system development GO:0001655 97 0.011
secondary metabolic process GO:0019748 3 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
blood vessel morphogenesis GO:0048514 216 0.011
oxoacid metabolic process GO:0043436 31 0.011
embryonic skeletal system development GO:0048706 97 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
response to unfolded protein GO:0006986 2 0.011
protein metabolic process GO:0019538 183 0.011
mesenchyme development GO:0060485 127 0.011
regulation of blood pressure GO:0008217 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of biosynthetic process GO:0009889 250 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
cellular response to light stimulus GO:0071482 4 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
cellular response to radiation GO:0071478 4 0.011
camera type eye morphogenesis GO:0048593 108 0.011
cellular pigmentation GO:0033059 30 0.011
single fertilization GO:0007338 3 0.011
positive regulation of camp metabolic process GO:0030816 2 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
positive regulation of reproductive process GO:2000243 2 0.011
autophagy GO:0006914 4 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
fat soluble vitamin metabolic process GO:0006775 4 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
alcohol biosynthetic process GO:0046165 2 0.011
glucose homeostasis GO:0042593 1 0.011
Rat
specification of symmetry GO:0009799 204 0.011
regulation of protein transport GO:0051223 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
response to drug GO:0042493 3 0.011
developmental growth GO:0048589 166 0.011
kidney epithelium development GO:0072073 23 0.011
endosomal transport GO:0016197 2 0.011
endocrine process GO:0050886 2 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
cellular response to retinoic acid GO:0071300 1 0.010
spermatid development GO:0007286 2 0.010
skeletal system development GO:0001501 181 0.010
regulation of calcium ion transport GO:0051924 2 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
post embryonic organ development GO:0048569 4 0.010
ovulation cycle process GO:0022602 2 0.010
actin mediated cell contraction GO:0070252 1 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
negative regulation of gene expression GO:0010629 65 0.010
macromolecular complex disassembly GO:0032984 1 0.010
anion transmembrane transport GO:0098656 12 0.010
Zebrafish
rna 3 end processing GO:0031123 2 0.010
cytoskeleton organization GO:0007010 96 0.010
gland development GO:0048732 143 0.010
long chain fatty acid transport GO:0015909 1 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
er nucleus signaling pathway GO:0006984 2 0.010
positive regulation of cell division GO:0051781 2 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
regulation of synapse assembly GO:0051963 3 0.010
periodic partitioning GO:0007365 1 0.010

aqp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011
musculoskeletal system disease DOID:17 0 0.010