Danio rerio

0 known processes

nkx2.1b

NK2 homeobox 1b

(Aliases: titf1b,nkx2.4b,nk2.1b,wu:fc31g10)

nkx2.1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.909
Human Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 217 0.809
Human Mouse Rat
forebrain development GO:0030900 96 0.777
Human Mouse
regulation of transcription dna templated GO:0006355 213 0.725
Human Mouse Rat
rna biosynthetic process GO:0032774 181 0.718
Human Mouse Rat
regulation of cellular biosynthetic process GO:0031326 245 0.714
Human Mouse Rat
diencephalon development GO:0021536 58 0.707
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.701
Human Mouse Rat
gene expression GO:0010467 252 0.681
Human Mouse Rat
nucleobase containing compound metabolic process GO:0006139 274 0.659
Human Mouse Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.651
Human Mouse Rat
brain development GO:0007420 293 0.633
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.609
Human Mouse Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.607
Human Mouse Rat
organic cyclic compound metabolic process GO:1901360 301 0.587
Human Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.585
Human Mouse Rat
transcription from rna polymerase ii promoter GO:0006366 80 0.582
Human Mouse Rat
nitrogen compound metabolic process GO:0006807 319 0.568
Human Mouse Rat
biosynthetic process GO:0009058 294 0.567
Human Mouse Rat
regulation of primary metabolic process GO:0080090 311 0.564
Human Mouse Rat
regulation of cellular metabolic process GO:0031323 320 0.542
Human Mouse Rat
cellular macromolecule biosynthetic process GO:0034645 224 0.520
Human Mouse Rat
heterocycle biosynthetic process GO:0018130 215 0.504
Human Mouse Rat
regulation of metabolic process GO:0019222 359 0.502
Human Mouse Rat
cell differentiation in spinal cord GO:0021515 40 0.486
Zebrafish
generation of neurons GO:0048699 385 0.484
Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.471
Human Mouse Rat
regulation of rna biosynthetic process GO:2001141 213 0.467
Human Mouse Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.449
Human Mouse Rat
organic substance biosynthetic process GO:1901576 289 0.449
Human Mouse Rat
rna metabolic process GO:0016070 219 0.435
Human Mouse Rat
neuron fate specification GO:0048665 20 0.434
cellular aromatic compound metabolic process GO:0006725 295 0.431
Human Mouse Rat
oligodendrocyte cell fate specification GO:0021778 4 0.429
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.421
Human Mouse Rat
cellular biosynthetic process GO:0044249 286 0.402
Human Mouse Rat
heterocycle metabolic process GO:0046483 290 0.396
Human Mouse Rat
forebrain generation of neurons GO:0021872 14 0.385
Mouse
camera type eye morphogenesis GO:0048593 108 0.374
cell fate commitment GO:0045165 99 0.371
Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.371
Human Mouse Rat
camera type eye development GO:0043010 222 0.348
cellular nitrogen compound metabolic process GO:0034641 290 0.343
Human Mouse Rat
embryonic organ development GO:0048568 381 0.338
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.333
Human Mouse Rat
skeletal system development GO:0001501 181 0.328
embryo development ending in birth or egg hatching GO:0009792 271 0.324
Zebrafish Worm
regionalization GO:0003002 274 0.315
Mouse
neuron fate commitment GO:0048663 26 0.315
Mouse
transcription dna templated GO:0006351 181 0.312
Human Mouse Rat
head development GO:0060322 303 0.310
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.309
Human Zebrafish
glial cell migration GO:0008347 3 0.305
Zebrafish
ventral spinal cord development GO:0021517 35 0.304
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.298
Mouse
cell migration GO:0016477 237 0.294
Human Zebrafish Mouse
spinal cord development GO:0021510 46 0.282
Zebrafish
glial cell fate specification GO:0021780 4 0.279
Zebrafish
cell fate specification GO:0001708 68 0.277
Zebrafish
regulation of developmental process GO:0050793 247 0.271
Human Zebrafish
tube morphogenesis GO:0035239 349 0.259
Human Zebrafish
determination of bilateral symmetry GO:0009855 204 0.257
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.255
Human Mouse Rat
specification of symmetry GO:0009799 204 0.253
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.252
Human Mouse Rat
central nervous system neuron differentiation GO:0021953 74 0.250
Zebrafish Mouse
cellular component morphogenesis GO:0032989 336 0.245
Human Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.237
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.236
Human Mouse Rat
floor plate development GO:0033504 15 0.234
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.234
Human Mouse Rat
morphogenesis of an epithelium GO:0002009 333 0.226
Human Zebrafish
forebrain neuron fate commitment GO:0021877 1 0.224
Mouse
regulation of gene expression GO:0010468 265 0.221
Human Mouse Rat
neuron differentiation GO:0030182 353 0.221
Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.217
Mouse
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.206
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.205
Human Mouse Rat
negative regulation of cellular process GO:0048523 283 0.201
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.197
Human Mouse Rat
locomotion GO:0040011 313 0.197
Human Zebrafish Mouse Worm
sensory organ morphogenesis GO:0090596 200 0.194
regulation of stem cell proliferation GO:0072091 2 0.192
cell part morphogenesis GO:0032990 246 0.191
Zebrafish Mouse
chordate embryonic development GO:0043009 271 0.186
Zebrafish
response to external stimulus GO:0009605 264 0.184
Zebrafish Mouse Rat
retina morphogenesis in camera type eye GO:0060042 79 0.181
negative regulation of cellular biosynthetic process GO:0031327 55 0.180
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 45 0.178
Mouse
response to chemical GO:0042221 320 0.176
Human Zebrafish Mouse Rat
cell projection organization GO:0030030 284 0.173
Zebrafish Mouse
cell morphogenesis GO:0000902 289 0.173
Human Zebrafish Mouse
pancreas development GO:0031016 84 0.170
Zebrafish
peripheral nervous system development GO:0007422 55 0.168
Zebrafish
central nervous system neuron development GO:0021954 29 0.164
pancreatic a cell development GO:0003322 2 0.163
larval development GO:0002164 2 0.163
digestive system development GO:0055123 289 0.155
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.155
Human Mouse Rat
oligodendrocyte differentiation GO:0048709 23 0.154
Zebrafish Mouse
endocrine system development GO:0035270 65 0.152
Human Zebrafish Mouse
positive regulation of cellular process GO:0048522 201 0.151
Human Mouse Rat
embryonic organ morphogenesis GO:0048562 274 0.151
Zebrafish
determination of left right symmetry GO:0007368 179 0.150
Zebrafish
localization of cell GO:0051674 244 0.146
Human Zebrafish Mouse
neuron projection development GO:0031175 180 0.145
Zebrafish Mouse
cell motility GO:0048870 244 0.145
Human Zebrafish Mouse
developmental growth GO:0048589 166 0.145
retina development in camera type eye GO:0060041 146 0.144
hindbrain development GO:0030902 91 0.140
axon guidance GO:0007411 86 0.140
Zebrafish Mouse
positive regulation of gene expression GO:0010628 71 0.139
Human Mouse Rat
forebrain neuron development GO:0021884 7 0.138
stem cell proliferation GO:0072089 4 0.135
regulation of biosynthetic process GO:0009889 250 0.132
Human Mouse Rat
growth GO:0040007 174 0.132
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.132
Human Mouse Rat
axonogenesis GO:0007409 152 0.126
Zebrafish Mouse
vasculature development GO:0001944 278 0.125
blood vessel morphogenesis GO:0048514 216 0.124
ventral spinal cord interneuron differentiation GO:0021514 12 0.123
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.121
Human Zebrafish Mouse
neuron fate determination GO:0048664 2 0.120
endocrine pancreas development GO:0031018 27 0.119
Zebrafish
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.119
Mouse
chemotaxis GO:0006935 104 0.117
Zebrafish Mouse
ventral midline development GO:0007418 13 0.116
Zebrafish
heart development GO:0007507 313 0.113
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.112
Human Mouse Rat
ventral spinal cord interneuron fate commitment GO:0060579 3 0.111
epidermal cell fate specification GO:0009957 4 0.110
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.109
Zebrafish Mouse
cell proliferation in forebrain GO:0021846 3 0.109
embryonic viscerocranium morphogenesis GO:0048703 52 0.108
gland development GO:0048732 143 0.108
Human Zebrafish Mouse
cell projection morphogenesis GO:0048858 244 0.108
Zebrafish Mouse
positive regulation of transcription dna templated GO:0045893 57 0.107
Human Mouse Rat
morphogenesis of an epithelial sheet GO:0002011 49 0.107
olfactory lobe development GO:0021988 4 0.106
multicellular organism growth GO:0035264 4 0.105
sensory organ development GO:0007423 393 0.105
negative regulation of macromolecule metabolic process GO:0010605 76 0.104
Mouse
cellular component movement GO:0006928 335 0.102
Human Zebrafish Mouse
angiogenesis GO:0001525 158 0.102
telencephalon development GO:0021537 14 0.102
Mouse
forebrain neuron differentiation GO:0021879 14 0.101
Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.101
negative regulation of metabolic process GO:0009892 86 0.099
Mouse
regulation of multicellular organism growth GO:0040014 4 0.099
regulation of biological quality GO:0065008 263 0.098
Rat
negative regulation of rna metabolic process GO:0051253 48 0.098
Mouse
neuron projection guidance GO:0097485 86 0.097
Zebrafish Mouse
exocrine pancreas development GO:0031017 28 0.096
auditory receptor cell fate commitment GO:0009912 4 0.094
eye morphogenesis GO:0048592 144 0.093
regulation of signal transduction GO:0009966 225 0.093
Human
positive regulation of cellular metabolic process GO:0031325 94 0.092
Human Mouse Rat
regulation of cell proliferation GO:0042127 37 0.091
positive regulation of nucleic acid templated transcription GO:1903508 57 0.087
Human Mouse Rat
regulation of cell communication GO:0010646 232 0.087
Human
neuron projection morphogenesis GO:0048812 161 0.086
Zebrafish Mouse
cranial nerve development GO:0021545 42 0.086
digestive tract development GO:0048565 265 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.085
Human Mouse Rat
olfactory bulb development GO:0021772 4 0.082
embryonic cranial skeleton morphogenesis GO:0048701 90 0.081
forebrain cell migration GO:0021885 1 0.079
Mouse
inner ear receptor cell development GO:0060119 20 0.079
negative regulation of cellular metabolic process GO:0031324 77 0.079
Mouse
negative regulation of gene expression GO:0010629 65 0.079
Mouse
eye development GO:0001654 277 0.075
positive regulation of rna biosynthetic process GO:1902680 57 0.074
Human Mouse Rat
epithelial tube morphogenesis GO:0060562 148 0.074
Human Zebrafish
auditory receptor cell fate determination GO:0042668 2 0.071
pronephros development GO:0048793 69 0.071
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.071
maintenance of location GO:0051235 4 0.070
positive regulation of metabolic process GO:0009893 108 0.070
Human Mouse Rat
water homeostasis GO:0030104 4 0.070
fin development GO:0033333 77 0.070
embryonic heart tube development GO:0035050 133 0.070
Zebrafish
blood vessel development GO:0001568 246 0.067
embryonic heart tube morphogenesis GO:0003143 108 0.067
Zebrafish
positive regulation of neural precursor cell proliferation GO:2000179 1 0.067
taxis GO:0042330 109 0.067
Zebrafish Mouse
cardiac chamber formation GO:0003207 4 0.065
Zebrafish
photoreceptor cell fate commitment GO:0046552 1 0.063
cell proliferation GO:0008283 80 0.062
Zebrafish
central nervous system myelin formation GO:0032289 1 0.062
glial cell differentiation GO:0010001 42 0.061
Zebrafish Mouse
regulation of multicellular organismal development GO:2000026 223 0.060
Human Zebrafish
inner ear receptor cell differentiation GO:0060113 29 0.060
positive regulation of biological process GO:0048518 253 0.060
Human Mouse Rat
neuron development GO:0048666 262 0.059
Zebrafish Mouse
positive regulation of developmental process GO:0051094 50 0.059
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.058
Mouse
appendage morphogenesis GO:0035107 56 0.057
spinal cord motor neuron differentiation GO:0021522 26 0.057
ectodermal placode development GO:0071696 37 0.055
cell fate specification involved in pattern specification GO:0060573 3 0.055
pancreatic d cell differentiation GO:0003311 2 0.055
connective tissue development GO:0061448 99 0.054
bmp signaling pathway GO:0030509 52 0.054
nerve development GO:0021675 45 0.054
anterior commissure morphogenesis GO:0021960 3 0.053
renal system development GO:0072001 94 0.052
pectoral fin development GO:0033339 50 0.052
somitogenesis GO:0001756 87 0.052
positive regulation of biosynthetic process GO:0009891 68 0.052
Human Mouse Rat
central nervous system neuron axonogenesis GO:0021955 18 0.052
cellular component assembly involved in morphogenesis GO:0010927 107 0.051
programmed cell death GO:0012501 119 0.051
erythrocyte differentiation GO:0030218 54 0.050
embryonic skeletal system morphogenesis GO:0048704 93 0.050
definitive hemopoiesis GO:0060216 18 0.050
inner ear receptor cell fate commitment GO:0060120 4 0.049
forebrain regionalization GO:0021871 4 0.049
Mouse
embryonic skeletal system development GO:0048706 97 0.049
regulation of anatomical structure morphogenesis GO:0022603 130 0.048
Human Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.048
Human
multi organism process GO:0051704 134 0.048
Rat
septum transversum development GO:0003343 4 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.047
Mouse
fin morphogenesis GO:0033334 53 0.047
aorta development GO:0035904 4 0.046
lipid storage GO:0019915 1 0.046
central nervous system myelination GO:0022010 2 0.046
neural retina development GO:0003407 49 0.045
regulation of cardiac chamber formation GO:1901210 2 0.045
Zebrafish
single organism metabolic process GO:0044710 217 0.044
Mouse
regulation of neuron projection development GO:0010975 40 0.044
neuron projection extension GO:1990138 45 0.044
skeletal system morphogenesis GO:0048705 102 0.044
ventral spinal cord interneuron specification GO:0021521 3 0.044
stem cell maintenance GO:0019827 4 0.043
type b pancreatic cell development GO:0003323 4 0.043
homeostatic process GO:0042592 142 0.043
embryonic camera type eye morphogenesis GO:0048596 19 0.043
negative regulation of rna biosynthetic process GO:1902679 45 0.042
Mouse
regulation of neural precursor cell proliferation GO:2000177 3 0.042
retinal ganglion cell axon guidance GO:0031290 35 0.042
negative regulation of cell death GO:0060548 60 0.042
oligodendrocyte cell fate commitment GO:0021779 5 0.042
Zebrafish
signal transduction GO:0007165 455 0.042
Human
regulation of cardiac chamber morphogenesis GO:1901219 2 0.041
Zebrafish
negative regulation of biosynthetic process GO:0009890 55 0.041
Mouse
regulation of heart morphogenesis GO:2000826 17 0.041
Zebrafish
sprouting angiogenesis GO:0002040 53 0.041
pronephric nephron development GO:0039019 14 0.040
regulation of dendrite development GO:0050773 3 0.040
digestive tract morphogenesis GO:0048546 231 0.040
pharyngeal muscle development GO:0043282 4 0.040
response to stress GO:0006950 263 0.039
Rat
regulation of mesenchymal cell proliferation GO:0010464 1 0.039
ear development GO:0043583 127 0.039
formation of primary germ layer GO:0001704 62 0.039
negative regulation of apoptotic process GO:0043066 55 0.039
embryonic camera type eye formation GO:0060900 10 0.039
heart morphogenesis GO:0003007 156 0.038
Zebrafish
odontogenesis of dentin containing tooth GO:0042475 1 0.038
polarized epithelial cell differentiation GO:0030859 4 0.038
establishment of localization GO:0051234 244 0.038
inner ear development GO:0048839 126 0.038
cellular amide metabolic process GO:0043603 4 0.037
spinal cord association neuron differentiation GO:0021527 1 0.036
specification of organ identity GO:0010092 2 0.036
regulation of neuron differentiation GO:0045664 56 0.036
glial cell fate commitment GO:0021781 6 0.036
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.036
Zebrafish
embryonic camera type eye development GO:0031076 29 0.035
development of primary female sexual characteristics GO:0046545 4 0.034
Rat
cell surface receptor signaling pathway GO:0007166 325 0.034
Human
regulation of endodermal cell fate specification GO:0042663 15 0.034
abducens nucleus development GO:0021742 2 0.034
regulation of epithelial cell proliferation GO:0050678 3 0.034
neuroblast fate determination GO:0007400 1 0.034
muscle cell differentiation GO:0042692 139 0.033
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.033
urogenital system development GO:0001655 97 0.033
endodermal cell differentiation GO:0035987 19 0.033
skin development GO:0043588 54 0.033
astrocyte differentiation GO:0048708 1 0.033
ectodermal placode formation GO:0060788 26 0.033
stem cell fate determination GO:0048867 1 0.032
striated muscle tissue development GO:0014706 110 0.032
Zebrafish
hemopoiesis GO:0030097 183 0.032
kidney development GO:0001822 92 0.032
membrane lipid biosynthetic process GO:0046467 2 0.032
negative regulation of gliogenesis GO:0014014 1 0.032
response to biotic stimulus GO:0009607 97 0.031
Rat
epidermal cell differentiation GO:0009913 36 0.031
female sex differentiation GO:0046660 4 0.031
Rat
gastrulation GO:0007369 208 0.031
primitive hemopoiesis GO:0060215 27 0.031
pancreatic d cell development GO:0003324 1 0.031
gliogenesis GO:0042063 45 0.030
Zebrafish Mouse
positive regulation of rna metabolic process GO:0051254 59 0.030
Human Mouse Rat
cardiac muscle tissue development GO:0048738 48 0.030
Zebrafish
regulation of neurogenesis GO:0050767 87 0.029
ectodermal placode morphogenesis GO:0071697 32 0.029
endodermal cell fate commitment GO:0001711 18 0.029
behavior GO:0007610 74 0.029
Mouse Rat
mechanoreceptor differentiation GO:0042490 37 0.029
negative regulation of programmed cell death GO:0043069 58 0.029
sensory system development GO:0048880 76 0.029
axon ensheathment in central nervous system GO:0032291 2 0.029
death GO:0016265 121 0.028
cell proliferation in hindbrain GO:0021534 4 0.028
cell death GO:0008219 121 0.028
response to alkaloid GO:0043279 2 0.028
somatic muscle development GO:0007525 4 0.028
cardiocyte differentiation GO:0035051 44 0.028
Zebrafish
exocrine system development GO:0035272 28 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.028
Mouse
axial mesoderm development GO:0048318 10 0.028
negative regulation of transcription dna templated GO:0045892 45 0.028
Mouse
central nervous system projection neuron axonogenesis GO:0021952 15 0.028
retina layer formation GO:0010842 24 0.028
neuroblast fate commitment GO:0014017 1 0.027
regulation of cell differentiation GO:0045595 142 0.027
Human
regulation of nervous system development GO:0051960 90 0.027
gtp metabolic process GO:0046039 4 0.027
regulation of system process GO:0044057 40 0.027
appendage development GO:0048736 80 0.027
positive regulation of epithelial cell differentiation GO:0030858 2 0.027
regulation of response to stimulus GO:0048583 269 0.026
Human
apoptotic process GO:0006915 116 0.026
phagocytosis GO:0006909 3 0.026
epidermis development GO:0008544 48 0.026
hatching gland development GO:0048785 3 0.026
cardiac muscle cell differentiation GO:0055007 30 0.026
Zebrafish
limbic system development GO:0021761 16 0.026
Mouse
regulation of organ morphogenesis GO:2000027 35 0.026
Zebrafish
developmental programmed cell death GO:0010623 4 0.026
immune system process GO:0002376 241 0.026
pharyngeal system development GO:0060037 18 0.025
regulation of jak stat cascade GO:0046425 3 0.025
organ formation GO:0048645 17 0.025
lens morphogenesis in camera type eye GO:0002089 7 0.025
neurological system process GO:0050877 62 0.025
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.024
otic placode formation GO:0043049 23 0.024
nephron morphogenesis GO:0072028 2 0.024
muscle structure development GO:0061061 196 0.024
Zebrafish
regulation of dendrite morphogenesis GO:0048814 3 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.024
Human
endodermal cell fate specification GO:0001714 17 0.024
olfactory placode development GO:0071698 12 0.024
axon development GO:0061564 166 0.024
Zebrafish Mouse
regulation of glial cell differentiation GO:0045685 4 0.024
dorsal spinal cord development GO:0021516 1 0.023
regulation of programmed cell death GO:0043067 101 0.023
epiboly GO:0090504 41 0.023
synaptic target recognition GO:0008039 1 0.023
gabaergic neuron differentiation GO:0097154 2 0.023
Mouse
organonitrogen compound biosynthetic process GO:1901566 47 0.023
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
mesenchyme development GO:0060485 127 0.022
Human
developmental cell growth GO:0048588 52 0.022
response to abiotic stimulus GO:0009628 122 0.022
Rat
cellular modified amino acid metabolic process GO:0006575 3 0.022
compound eye development GO:0048749 2 0.022
regulation of apoptotic process GO:0042981 98 0.022
aging GO:0007568 2 0.022
striated muscle cell differentiation GO:0051146 129 0.022
Zebrafish
cranial ganglion development GO:0061550 3 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.022
Human Mouse Rat
positive regulation of jak stat cascade GO:0046427 2 0.022
endoderm formation GO:0001706 29 0.022
photoreceptor cell fate specification GO:0043704 1 0.021
camera type eye photoreceptor cell differentiation GO:0060219 19 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
regulation of signaling GO:0023051 235 0.021
Human
embryonic hemopoiesis GO:0035162 53 0.021
enteroendocrine cell differentiation GO:0035883 9 0.021
dopaminergic neuron differentiation GO:0071542 14 0.021
mesenchymal cell development GO:0014031 78 0.021
Human
phosphorus metabolic process GO:0006793 109 0.021
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.021
Zebrafish
ear morphogenesis GO:0042471 64 0.021
cellular response to chemical stimulus GO:0070887 157 0.020
Human
proximal distal pattern formation GO:0009954 1 0.020
vasculogenesis GO:0001570 41 0.020
neural nucleus development GO:0048857 15 0.020
Human Mouse
amine metabolic process GO:0009308 2 0.020
axon extension GO:0048675 45 0.020
response to glucose GO:0009749 3 0.020
small molecule metabolic process GO:0044281 77 0.020
renal tubule morphogenesis GO:0061333 1 0.020
dna templated transcription initiation GO:0006352 1 0.020
positive regulation of cell cycle GO:0045787 3 0.019
stem cell fate commitment GO:0048865 1 0.019
blood circulation GO:0008015 87 0.019
Rat
apoptotic process involved in development GO:1902742 2 0.019
regulation of cell death GO:0010941 103 0.019
pronephric glomerulus development GO:0039021 13 0.019
cellular response to external stimulus GO:0071496 2 0.019
regulation of cell fate commitment GO:0010453 22 0.019
floor plate formation GO:0021508 12 0.019
Zebrafish
thyroid gland development GO:0030878 12 0.019
Human Zebrafish Mouse
guanosine containing compound metabolic process GO:1901068 4 0.019
cellular component assembly GO:0022607 170 0.019
motor neuron axon guidance GO:0008045 23 0.019
Zebrafish
mesenchymal cell proliferation GO:0010463 1 0.019
pigment granule aggregation in cell center GO:0051877 8 0.019
wound healing GO:0042060 90 0.019
neural crest cell differentiation GO:0014033 72 0.018
stem cell differentiation GO:0048863 117 0.018
Human
facial nucleus development GO:0021754 7 0.018
convergent extension involved in organogenesis GO:0060029 10 0.018
catecholamine metabolic process GO:0006584 2 0.018
adenohypophysis development GO:0021984 15 0.018
nephron tubule morphogenesis GO:0072078 1 0.018
nose development GO:0043584 3 0.018
apoptotic process involved in morphogenesis GO:0060561 2 0.018
photoreceptor cell development GO:0042461 40 0.018
lateral line ganglion development GO:0048890 2 0.018
regulation of cellular component organization GO:0051128 86 0.018
Human
somite development GO:0061053 96 0.018
cardiogenic plate morphogenesis GO:0003142 1 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
neuroblast proliferation GO:0007405 2 0.018
nephron epithelium morphogenesis GO:0072088 1 0.018
hair cell differentiation GO:0035315 32 0.018
gtp catabolic process GO:0006184 2 0.017
response to monosaccharide GO:0034284 3 0.017
positive regulation of neurogenesis GO:0050769 24 0.017
muscle organ development GO:0007517 101 0.017
mitotic cell cycle process GO:1903047 48 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.017
response to external biotic stimulus GO:0043207 97 0.017
Rat
cartilage development GO:0051216 96 0.017
oxoacid metabolic process GO:0043436 31 0.017
pons development GO:0021548 11 0.017
cellular ketone metabolic process GO:0042180 11 0.017
catecholamine biosynthetic process GO:0042423 2 0.017
positive regulation of secretion GO:0051047 1 0.016
pectoral fin morphogenesis GO:0035138 29 0.016
midbrain hindbrain boundary development GO:0030917 23 0.016
positive regulation of multicellular organismal process GO:0051240 52 0.016
embryonic pectoral fin morphogenesis GO:0035118 24 0.016
negative regulation of signaling GO:0023057 96 0.016
Human
nephric duct development GO:0072176 13 0.016
post embryonic morphogenesis GO:0009886 4 0.016
notochord development GO:0030903 54 0.016
heart jogging GO:0003146 40 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.016
glucose homeostasis GO:0042593 1 0.016
forebrain anterior posterior pattern specification GO:0021797 3 0.016
retinal rod cell development GO:0046548 4 0.016
embryonic heart tube formation GO:0003144 1 0.016
eye photoreceptor cell development GO:0042462 30 0.015
cartilage morphogenesis GO:0060536 13 0.015
epithelial cell differentiation GO:0030855 116 0.015
Mouse
inner ear morphogenesis GO:0042472 63 0.015
organelle organization GO:0006996 227 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
thalamus development GO:0021794 6 0.015
somatic stem cell maintenance GO:0035019 1 0.015
ventricular system development GO:0021591 12 0.015
regulation of cell migration GO:0030334 40 0.015
Human
eye photoreceptor cell differentiation GO:0001754 45 0.015
regulation of gastrulation GO:0010470 24 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
response to carbohydrate GO:0009743 3 0.015
midbrain development GO:0030901 28 0.015
segmentation GO:0035282 97 0.015
catechol containing compound metabolic process GO:0009712 2 0.015
regulation of reproductive process GO:2000241 4 0.014
optokinetic behavior GO:0007634 9 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
mesoderm morphogenesis GO:0048332 51 0.014
otic vesicle formation GO:0030916 27 0.014
peptide metabolic process GO:0006518 1 0.014
carbohydrate homeostasis GO:0033500 1 0.014
wnt signaling pathway GO:0016055 80 0.014
axial mesodermal cell fate specification GO:0048327 3 0.014
otic vesicle development GO:0071599 42 0.014
neuron migration GO:0001764 22 0.014
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.014
Human
pigmentation GO:0043473 85 0.014
heart looping GO:0001947 94 0.014
Zebrafish
heart process GO:0003015 71 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of synapse organization GO:0050807 3 0.014
regulation of protein complex assembly GO:0043254 3 0.014
paraxial mesoderm morphogenesis GO:0048340 2 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
lateral line system development GO:0048925 76 0.014
brain morphogenesis GO:0048854 18 0.014
response to other organism GO:0051707 97 0.014
Rat
negative regulation of catabolic process GO:0009895 3 0.013
phenol containing compound biosynthetic process GO:0046189 4 0.013

nkx2.1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.104
disease of metabolism DOID:0014667 0 0.025