Danio rerio

0 known processes

f2rl1.1

coagulation factor II (thrombin) receptor-like 1.1

(Aliases: f2rl1,MGC158264,zgc:158264,PAR2a)

f2rl1.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
specification of symmetry GO:0009799 204 0.109
larval development GO:0002164 2 0.090
digestive tract morphogenesis GO:0048546 231 0.083
gastrulation GO:0007369 208 0.082
cell motility GO:0048870 244 0.072
Human Mouse
protein secretion GO:0009306 1 0.071
Human Mouse
chordate embryonic development GO:0043009 271 0.070
regulation of stem cell differentiation GO:2000736 4 0.067
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.067
cell migration GO:0016477 237 0.062
Human Mouse
convergent extension GO:0060026 118 0.059
morphogenesis of an epithelium GO:0002009 333 0.058
immune system process GO:0002376 241 0.058
Human Zebrafish Mouse
mitochondrion organization GO:0007005 4 0.057
convergent extension involved in gastrulation GO:0060027 71 0.057
fertilization GO:0009566 3 0.056
tube morphogenesis GO:0035239 349 0.055
localization of cell GO:0051674 244 0.055
Human Mouse
digestive system development GO:0055123 289 0.052
locomotion GO:0040011 313 0.051
Human Mouse
single fertilization GO:0007338 3 0.051
regulation of muscle contraction GO:0006937 3 0.048
digestive tract development GO:0048565 265 0.047
hemopoiesis GO:0030097 183 0.047
Human Zebrafish Mouse
cellular component movement GO:0006928 335 0.047
Human Mouse
single organism localization GO:1902578 225 0.046
Human Mouse
positive regulation of biological process GO:0048518 253 0.043
Human Mouse Rat
pigmentation GO:0043473 85 0.043
synaptic vesicle localization GO:0097479 1 0.042
nuclear migration GO:0007097 3 0.041
regulation of synapse assembly GO:0051963 3 0.041
ameboidal type cell migration GO:0001667 143 0.040
maintenance of location GO:0051235 4 0.040
heart development GO:0007507 313 0.040
signal transduction GO:0007165 455 0.040
Human Zebrafish Mouse
system process GO:0003008 185 0.039
Mouse Rat
synaptic growth at neuromuscular junction GO:0051124 2 0.039
regulation of cell communication GO:0010646 232 0.039
Human Mouse
response to wounding GO:0009611 116 0.038
Human
sensory organ development GO:0007423 393 0.037
regulation of synapse organization GO:0050807 3 0.036
heart morphogenesis GO:0003007 156 0.036
developmental growth GO:0048589 166 0.035
positive regulation of epithelial cell proliferation GO:0050679 1 0.034
central nervous system development GO:0007417 387 0.034
modification dependent protein catabolic process GO:0019941 3 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.033
lateral inhibition GO:0046331 1 0.033
regulation of reproductive process GO:2000241 4 0.033
epithelial cell morphogenesis GO:0003382 2 0.033
cellular response to external stimulus GO:0071496 2 0.032
cell fate commitment GO:0045165 99 0.032
determination of left right symmetry GO:0007368 179 0.031
segment polarity determination GO:0007367 1 0.031
renal system development GO:0072001 94 0.031
embryonic organ morphogenesis GO:0048562 274 0.030
cell part morphogenesis GO:0032990 246 0.030
epidermal cell fate specification GO:0009957 4 0.030
blood vessel development GO:0001568 246 0.029
cellular component morphogenesis GO:0032989 336 0.028
Zebrafish
regulation of signal transduction GO:0009966 225 0.028
Human Mouse
cognition GO:0050890 1 0.028
negative regulation of biological process GO:0048519 304 0.028
Human Zebrafish
regulation of cardiac muscle tissue development GO:0055024 1 0.028
regulation of protein complex assembly GO:0043254 3 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
response to chemical GO:0042221 320 0.027
Human Mouse
urogenital system development GO:0001655 97 0.027
embryonic heart tube development GO:0035050 133 0.027
regulation of protein polymerization GO:0032271 2 0.027
synaptic vesicle transport GO:0048489 1 0.027
regulation of biological quality GO:0065008 263 0.026
Human Mouse Rat
regulation of establishment of protein localization GO:0070201 4 0.026
Human Mouse
regulation of cell shape GO:0008360 1 0.026
positive regulation of cellular process GO:0048522 201 0.026
Human Mouse
regulation of cytoplasmic transport GO:1903649 4 0.026
establishment of localization GO:0051234 244 0.026
Human Mouse
regeneration GO:0031099 91 0.026
positive regulation of protein complex assembly GO:0031334 2 0.025
positive regulation of protein polymerization GO:0032273 2 0.025
autophagy GO:0006914 4 0.025
kupffer s vesicle development GO:0070121 50 0.025
regulation of filopodium assembly GO:0051489 2 0.025
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.025
multicellular organismal metabolic process GO:0044236 2 0.025
cell projection morphogenesis GO:0048858 244 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
protein dephosphorylation GO:0006470 3 0.025
smooth muscle contraction GO:0006939 2 0.024
regulation of tube size GO:0035150 2 0.024
Mouse Rat
proteasomal protein catabolic process GO:0010498 2 0.024
tissue remodeling GO:0048771 4 0.024
ion transport GO:0006811 114 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.023
positive regulation of immune effector process GO:0002699 3 0.023
Human
stem cell maintenance GO:0019827 4 0.023
positive regulation of cytokine production GO:0001819 2 0.023
Human
morphogenesis of an epithelial sheet GO:0002011 49 0.022
regulation of primary metabolic process GO:0080090 311 0.022
Human
brain development GO:0007420 293 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
endocrine process GO:0050886 2 0.022
Mouse
regulation of cytokine production GO:0001817 3 0.022
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
Human
keratinocyte differentiation GO:0030216 0 0.021
cell morphogenesis GO:0000902 289 0.021
Zebrafish
amine metabolic process GO:0009308 2 0.021
adult behavior GO:0030534 2 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
regulation of protein transport GO:0051223 3 0.021
Human Mouse
positive regulation of secretion GO:0051047 1 0.020
Human Mouse
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.020
Human Mouse
apoptotic process involved in development GO:1902742 2 0.020
skeletal system development GO:0001501 181 0.020
cellular localization GO:0051641 97 0.020
Human Mouse
positive regulation of transport GO:0051050 2 0.020
Human Mouse
cellular response to nutrient levels GO:0031669 2 0.020
cell migration involved in gastrulation GO:0042074 79 0.020
regulation of organ growth GO:0046620 3 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of response to stimulus GO:0048583 269 0.020
Human Mouse
positive regulation of blood circulation GO:1903524 2 0.020
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.020
regionalization GO:0003002 274 0.020
growth GO:0040007 174 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
connective tissue development GO:0061448 99 0.019
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.019
Mouse Rat
cytokinesis GO:0000910 3 0.019
regulation of protein catabolic process GO:0042176 1 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
Human
regulation of signaling GO:0023051 235 0.019
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.019
Human
protein localization to nucleus GO:0034504 3 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
Human Zebrafish Mouse
protein targeting to nucleus GO:0044744 3 0.018
myeloid cell differentiation GO:0030099 86 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
Human
cell projection organization GO:0030030 284 0.018
Mouse
ear development GO:0043583 127 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
negative regulation of stem cell differentiation GO:2000737 2 0.018
Zebrafish
b cell activation GO:0042113 2 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
negative regulation of signal transduction GO:0009968 94 0.018
Human
lipid storage GO:0019915 1 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
neurotransmitter transport GO:0006836 2 0.018
tube closure GO:0060606 1 0.018
protein metabolic process GO:0019538 183 0.018
inner ear receptor cell fate commitment GO:0060120 4 0.018
adherens junction organization GO:0034332 4 0.018
cellular ketone metabolic process GO:0042180 11 0.018
response to carbohydrate GO:0009743 3 0.018
bmp signaling pathway GO:0030509 52 0.018
calcium ion transport into cytosol GO:0060402 3 0.017
regulation of striated muscle contraction GO:0006942 2 0.017
cellular component biogenesis GO:0044085 178 0.017
Mouse
organelle localization GO:0051640 49 0.017
response to stress GO:0006950 263 0.017
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
Human
organelle organization GO:0006996 227 0.017
Human
cellular amine metabolic process GO:0044106 2 0.017
regulation of glial cell differentiation GO:0045685 4 0.017
positive regulation of muscle tissue development GO:1901863 1 0.017
cytosolic calcium ion transport GO:0060401 3 0.017
establishment of synaptic vesicle localization GO:0097480 1 0.017
regulation of metabolic process GO:0019222 359 0.016
Human Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.016
gtp catabolic process GO:0006184 2 0.016
cellular protein metabolic process GO:0044267 129 0.016
regulation of heart growth GO:0060420 2 0.016
renal system process involved in regulation of blood volume GO:0001977 1 0.016
Rat
wnt signaling pathway GO:0016055 80 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
Human Mouse
transcription dna templated GO:0006351 181 0.016
Human
synaptic vesicle endocytosis GO:0048488 1 0.016
regulation of autophagy GO:0010506 3 0.016
establishment of melanosome localization GO:0032401 19 0.016
endoderm development GO:0007492 49 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
Mouse
nucleocytoplasmic transport GO:0006913 4 0.016
regulation of cell projection assembly GO:0060491 4 0.016
Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.016
positive regulation of muscle organ development GO:0048636 1 0.016
positive regulation of striated muscle tissue development GO:0045844 1 0.016
gland development GO:0048732 143 0.016
regulation of developmental process GO:0050793 247 0.016
Zebrafish
regulation of wound healing GO:0061041 2 0.016
Human
neurological system process GO:0050877 62 0.016
response to external stimulus GO:0009605 264 0.016
Human Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
phosphorus metabolic process GO:0006793 109 0.016
Human Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.015
biosynthetic process GO:0009058 294 0.015
Human
anterior posterior pattern specification GO:0009952 152 0.015
metal ion transport GO:0030001 58 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
Human Mouse
canonical wnt signaling pathway GO:0060070 48 0.015
peptide transport GO:0015833 1 0.015
nuclear import GO:0051170 3 0.015
cellular response to starvation GO:0009267 1 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
epiboly GO:0090504 41 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
protein import into nucleus GO:0006606 3 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
primary neural tube formation GO:0014020 1 0.015
positive regulation of catabolic process GO:0009896 4 0.015
mesenchymal cell development GO:0014031 78 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
Human
establishment of localization in cell GO:0051649 77 0.015
Human Mouse
notochord development GO:0030903 54 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
Human Zebrafish Mouse Rat
negative regulation of synapse assembly GO:0051964 2 0.015
melanosome transport GO:0032402 19 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
fin regeneration GO:0031101 51 0.015
pectoral fin development GO:0033339 50 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
Human
regulation of cytoskeleton organization GO:0051493 11 0.014
Human
rho protein signal transduction GO:0007266 5 0.014
Human Mouse
stem cell proliferation GO:0072089 4 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
female gonad development GO:0008585 4 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
Human
regulation of epithelial cell proliferation GO:0050678 3 0.014
motor neuron axon guidance GO:0008045 23 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.014
protein import GO:0017038 3 0.014
positive regulation of cell cycle GO:0045787 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
negative regulation of defense response GO:0031348 2 0.014
regulation of apoptotic process GO:0042981 98 0.014
regulation of cellular response to growth factor stimulus GO:0090287 35 0.014
renal tubule morphogenesis GO:0061333 1 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
peptide metabolic process GO:0006518 1 0.014
nephron morphogenesis GO:0072028 2 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
polyol metabolic process GO:0019751 1 0.014
generation of neurons GO:0048699 385 0.014
actin filament based movement GO:0030048 1 0.014
negative regulation of cell communication GO:0010648 96 0.014
Human
positive regulation of secretion by cell GO:1903532 1 0.014
Human Mouse
intracellular signal transduction GO:0035556 85 0.014
Human Mouse
head development GO:0060322 303 0.014
stem cell division GO:0017145 1 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
protein polymerization GO:0051258 4 0.013
regulation of protein targeting GO:1903533 2 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
retina development in camera type eye GO:0060041 146 0.013
wound healing GO:0042060 90 0.013
Human
cellular response to organic substance GO:0071310 105 0.013
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
Human
neuroblast proliferation GO:0007405 2 0.013
stem cell differentiation GO:0048863 117 0.013
Zebrafish
macromolecule modification GO:0043412 111 0.013
cartilage condensation GO:0001502 3 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
somatic muscle development GO:0007525 4 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
circulatory system process GO:0003013 87 0.013
Mouse Rat
response to other organism GO:0051707 97 0.013
Human Mouse
multicellular organism growth GO:0035264 4 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
somatic stem cell maintenance GO:0035019 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
Human
sequestering of metal ion GO:0051238 3 0.013
homeostatic process GO:0042592 142 0.013
Human Mouse
trabecula morphogenesis GO:0061383 2 0.013
small molecule metabolic process GO:0044281 77 0.013
meiosis i GO:0007127 1 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
Human
axon ensheathment in central nervous system GO:0032291 2 0.013
developmental programmed cell death GO:0010623 4 0.013
epithelial cell morphogenesis involved in gastrulation GO:0003381 1 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
single organism organelle organization GO:1902589 199 0.013
Human
positive regulation of epithelial cell migration GO:0010634 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
Mouse Rat
cellular response to chemical stimulus GO:0070887 157 0.013
Human
protein modification process GO:0036211 100 0.013
response to drug GO:0042493 3 0.012
inner ear development GO:0048839 126 0.012
exocytosis GO:0006887 1 0.012
Human
single organism nuclear import GO:1902593 3 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
Human
regulation of multicellular organism growth GO:0040014 4 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
regulation of endocrine process GO:0044060 2 0.012
Mouse
organic acid metabolic process GO:0006082 31 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.012
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
Human
developmental pigmentation GO:0048066 48 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
Human
neural tube development GO:0021915 62 0.012
oxoacid metabolic process GO:0043436 31 0.012
epithelial cell differentiation GO:0030855 116 0.012
Human
lateral line system development GO:0048925 76 0.012
energy reserve metabolic process GO:0006112 2 0.012
vasculature development GO:0001944 278 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
hepaticobiliary system development GO:0061008 98 0.012
biological adhesion GO:0022610 40 0.012
Zebrafish
nuclear transport GO:0051169 4 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
Human
regulation of cell activation GO:0050865 1 0.012
Human
regulation of blood circulation GO:1903522 32 0.012
Mouse Rat
cortical cytoskeleton organization GO:0030865 1 0.012
cell cycle process GO:0022402 53 0.012
negative regulation of secretion GO:0051048 2 0.012
Human
pronephros development GO:0048793 69 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.011
Human
cell growth GO:0016049 57 0.011
peptidyl tyrosine dephosphorylation GO:0035335 1 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
Human Mouse
skeletal system morphogenesis GO:0048705 102 0.011
actin mediated cell contraction GO:0070252 1 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
Human
synaptic vesicle recycling GO:0036465 1 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
Human
positive regulation of muscle cell differentiation GO:0051149 1 0.011
rna metabolic process GO:0016070 219 0.011
Human
transport GO:0006810 220 0.011
Human Mouse
golgi vesicle transport GO:0048193 3 0.011
gene expression GO:0010467 252 0.011
Human
meiotic chromosome segregation GO:0045132 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
multi organism process GO:0051704 134 0.011
Human Mouse
negative regulation of kinase activity GO:0033673 4 0.011
negative regulation of multi organism process GO:0043901 3 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
Human Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.011
negative regulation of signaling GO:0023057 96 0.011
Human
embryonic digestive tract morphogenesis GO:0048557 3 0.011
protein complex localization GO:0031503 1 0.011
camera type eye development GO:0043010 222 0.011
hatching gland development GO:0048785 3 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
regulation of metal ion transport GO:0010959 4 0.011
neuron projection morphogenesis GO:0048812 161 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
regulation of gene expression GO:0010468 265 0.011
Human
developmental growth involved in morphogenesis GO:0060560 86 0.011
positive regulation of wound healing GO:0090303 1 0.011
embryonic organ development GO:0048568 381 0.011
positive regulation of striated muscle cell differentiation GO:0051155 1 0.011
small molecule catabolic process GO:0044282 3 0.011
sensory perception of touch GO:0050975 2 0.011
chemosensory behavior GO:0007635 1 0.011
phosphorylation GO:0016310 69 0.011
Human Mouse
regulation of cardiac muscle cell differentiation GO:2000725 1 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
regulation of binding GO:0051098 3 0.011
meiotic nuclear division GO:0007126 4 0.011
compound eye development GO:0048749 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
response to monosaccharide GO:0034284 3 0.011
nucleic acid templated transcription GO:0097659 181 0.010
Human
negative regulation of catabolic process GO:0009895 3 0.010
response to fibroblast growth factor GO:0071774 22 0.010
mitotic cell cycle GO:0000278 64 0.010
heterocycle metabolic process GO:0046483 290 0.010
Human
regulation of inflammatory response GO:0050727 2 0.010
gastrulation with mouth forming second GO:0001702 44 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
endocardial cushion morphogenesis GO:0003203 3 0.010
cell migration involved in heart development GO:0060973 22 0.010
epithelial cell development GO:0002064 42 0.010
Human
neuron projection development GO:0031175 180 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
Zebrafish
somitogenesis GO:0001756 87 0.010
regulation of immune system process GO:0002682 34 0.010
Human Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.010

f2rl1.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
connective tissue disease DOID:65 0 0.011