Danio rerio

0 known processes

zgc:136773

zgc:136773

zgc:136773 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of macromolecule metabolic process GO:0060255 317 0.696
biosynthetic process GO:0009058 294 0.599
regulation of metabolic process GO:0019222 359 0.452
gene expression GO:0010467 252 0.405
regionalization GO:0003002 274 0.386
regulation of primary metabolic process GO:0080090 311 0.365
aromatic compound biosynthetic process GO:0019438 217 0.331
rna metabolic process GO:0016070 219 0.328
cellular macromolecule metabolic process GO:0044260 391 0.317
nucleobase containing compound metabolic process GO:0006139 274 0.302
embryonic organ development GO:0048568 381 0.298
nucleic acid metabolic process GO:0090304 244 0.283
rna biosynthetic process GO:0032774 181 0.281
heterocycle biosynthetic process GO:0018130 215 0.255
cellular aromatic compound metabolic process GO:0006725 295 0.253
embryonic organ morphogenesis GO:0048562 274 0.251
chordate embryonic development GO:0043009 271 0.205
larval development GO:0002164 2 0.202
heterocycle metabolic process GO:0046483 290 0.194
maintenance of location GO:0051235 4 0.184
nuclear import GO:0051170 3 0.180
organic cyclic compound biosynthetic process GO:1901362 223 0.166
digestive tract morphogenesis GO:0048546 231 0.163
regulation of nitrogen compound metabolic process GO:0051171 251 0.163
locomotion GO:0040011 313 0.155
cell surface receptor signaling pathway GO:0007166 325 0.153
cellular nitrogen compound metabolic process GO:0034641 290 0.153
nitrogen compound metabolic process GO:0006807 319 0.152
protein targeting to nucleus GO:0044744 3 0.150
regulation of cellular metabolic process GO:0031323 320 0.140
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.140
neuron projection extension GO:1990138 45 0.139
homeostatic process GO:0042592 142 0.138
positive regulation of cellular process GO:0048522 201 0.133
regulation of rna biosynthetic process GO:2001141 213 0.131
transcription dna templated GO:0006351 181 0.126
nucleobase containing compound biosynthetic process GO:0034654 205 0.120
regulation of signal transduction GO:0009966 225 0.116
regulation of protein catabolic process GO:0042176 1 0.116
nucleic acid templated transcription GO:0097659 181 0.112
regulation of nucleic acid templated transcription GO:1903506 213 0.108
regulation of nucleocytoplasmic transport GO:0046822 2 0.103
cellular macromolecule biosynthetic process GO:0034645 224 0.099
regulation of biosynthetic process GO:0009889 250 0.096
organic cyclic compound metabolic process GO:1901360 301 0.095
tube morphogenesis GO:0035239 349 0.094
single organism nuclear import GO:1902593 3 0.090
hematopoietic or lymphoid organ development GO:0048534 191 0.088
generation of neurons GO:0048699 385 0.081
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.081
regulation of protein import into nucleus GO:0042306 2 0.080
protein import into nucleus GO:0006606 3 0.080
nucleocytoplasmic transport GO:0006913 4 0.080
regulation of gene expression GO:0010468 265 0.079
negative regulation of signaling GO:0023057 96 0.077
positive regulation of cellular metabolic process GO:0031325 94 0.077
programmed cell death GO:0012501 119 0.076
macromolecule biosynthetic process GO:0009059 227 0.076
regulation of cell communication GO:0010646 232 0.076
regulation of transcription dna templated GO:0006355 213 0.073
establishment of protein localization to organelle GO:0072594 4 0.072
organic substance biosynthetic process GO:1901576 289 0.071
cellular component morphogenesis GO:0032989 336 0.070
gland development GO:0048732 143 0.070
cellular nitrogen compound biosynthetic process GO:0044271 218 0.069
cellular protein catabolic process GO:0044257 4 0.069
nuclear transport GO:0051169 4 0.069
regulation of biological quality GO:0065008 263 0.067
head development GO:0060322 303 0.067
regulation of intracellular protein transport GO:0033157 3 0.066
anterior posterior pattern specification GO:0009952 152 0.065
embryo development ending in birth or egg hatching GO:0009792 271 0.065
protein import GO:0017038 3 0.064
negative regulation of gene expression GO:0010629 65 0.063
signal transduction GO:0007165 455 0.062
morphogenesis of an epithelium GO:0002009 333 0.062
negative regulation of cellular process GO:0048523 283 0.061
mesenchyme development GO:0060485 127 0.061
regulation of establishment of protein localization GO:0070201 4 0.061
regulation of signaling GO:0023051 235 0.061
neuron differentiation GO:0030182 353 0.060
regulation of cell fate specification GO:0042659 20 0.059
regulation of response to stimulus GO:0048583 269 0.059
ubiquitin dependent protein catabolic process GO:0006511 3 0.058
lipid storage GO:0019915 1 0.056
cellular biosynthetic process GO:0044249 286 0.056
multi organism process GO:0051704 134 0.056
regulation of rna metabolic process GO:0051252 224 0.056
heart looping GO:0001947 94 0.056
multicellular organism growth GO:0035264 4 0.053
positive regulation of biological process GO:0048518 253 0.052
aging GO:0007568 2 0.051
positive regulation of transport GO:0051050 2 0.051
regulation of multicellular organism growth GO:0040014 4 0.051
meiotic nuclear division GO:0007126 4 0.051
cellular response to external stimulus GO:0071496 2 0.050
protein metabolic process GO:0019538 183 0.050
mrna metabolic process GO:0016071 20 0.050
regulation of intracellular signal transduction GO:1902531 57 0.050
multi organism reproductive process GO:0044703 36 0.050
positive regulation of macromolecule metabolic process GO:0010604 93 0.050
transcription from rna polymerase ii promoter GO:0006366 80 0.049
skin development GO:0043588 54 0.049
neuron projection morphogenesis GO:0048812 161 0.048
heart morphogenesis GO:0003007 156 0.048
localization of cell GO:0051674 244 0.047
protein localization to nucleus GO:0034504 3 0.047
negative regulation of cell communication GO:0010648 96 0.046
cell motility GO:0048870 244 0.045
regulation of protein transport GO:0051223 3 0.045
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.044
specification of symmetry GO:0009799 204 0.044
heart development GO:0007507 313 0.044
retinal ganglion cell axon guidance GO:0031290 35 0.044
regulation of proteolysis GO:0030162 24 0.044
proteasomal protein catabolic process GO:0010498 2 0.044
developmental growth GO:0048589 166 0.044
cell morphogenesis GO:0000902 289 0.044
epidermis development GO:0008544 48 0.043
apoptotic process GO:0006915 116 0.043
macromolecular complex assembly GO:0065003 35 0.043
cell cycle GO:0007049 93 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.040
blood vessel development GO:0001568 246 0.040
cellular response to extracellular stimulus GO:0031668 2 0.039
regulation of mrna processing GO:0050684 3 0.039
epithelial cell differentiation GO:0030855 116 0.039
regulation of meiotic cell cycle GO:0051445 1 0.039
cell death GO:0008219 121 0.038
negative regulation of macromolecule metabolic process GO:0010605 76 0.038
regulation of localization GO:0032879 104 0.038
regulation of molecular function GO:0065009 70 0.038
negative regulation of catabolic process GO:0009895 3 0.037
negative regulation of rna biosynthetic process GO:1902679 45 0.037
vasculature development GO:0001944 278 0.037
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.037
carboxylic acid metabolic process GO:0019752 22 0.036
regulation of macromolecule biosynthetic process GO:0010556 225 0.036
skeletal system development GO:0001501 181 0.036
response to stress GO:0006950 263 0.036
central nervous system development GO:0007417 387 0.036
negative regulation of biological process GO:0048519 304 0.036
gastrulation GO:0007369 208 0.035
digestive system development GO:0055123 289 0.035
modification dependent macromolecule catabolic process GO:0043632 3 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.034
heart valve formation GO:0003188 4 0.033
embryonic cranial skeleton morphogenesis GO:0048701 90 0.033
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.032
positive regulation of multicellular organismal process GO:0051240 52 0.032
neural crest formation GO:0014029 14 0.031
immune system development GO:0002520 191 0.031
negative regulation of cellular biosynthetic process GO:0031327 55 0.030
embryonic heart tube morphogenesis GO:0003143 108 0.030
positive regulation of metabolic process GO:0009893 108 0.030
embryonic skeletal system development GO:0048706 97 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
skeletal system morphogenesis GO:0048705 102 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
connective tissue development GO:0061448 99 0.029
cell fate specification GO:0001708 68 0.029
cell growth GO:0016049 57 0.028
cell fate commitment GO:0045165 99 0.028
determination of bilateral symmetry GO:0009855 204 0.028
negative regulation of biosynthetic process GO:0009890 55 0.028
cellular ketone metabolic process GO:0042180 11 0.028
oxoacid metabolic process GO:0043436 31 0.028
female meiotic division GO:0007143 2 0.028
negative regulation of nuclear division GO:0051784 3 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.027
gamete generation GO:0007276 33 0.027
response to organic substance GO:0010033 153 0.027
negative regulation of metabolic process GO:0009892 86 0.027
regulation of anatomical structure morphogenesis GO:0022603 130 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
positive regulation of mrna metabolic process GO:1903313 2 0.027
negative regulation of chromosome organization GO:2001251 1 0.027
chemotaxis GO:0006935 104 0.026
digestive tract development GO:0048565 265 0.026
muscle tissue development GO:0060537 110 0.025
macromolecular complex subunit organization GO:0043933 74 0.024
negative regulation of nucleic acid templated transcription GO:1903507 45 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.024
positive regulation of chromosome organization GO:2001252 1 0.024
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.023
embryonic skeletal system morphogenesis GO:0048704 93 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
angiogenesis GO:0001525 158 0.023
response to chemical GO:0042221 320 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.023
somitogenesis GO:0001756 87 0.023
regulation of developmental process GO:0050793 247 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.023
negative regulation of transcription dna templated GO:0045892 45 0.023
neuron projection development GO:0031175 180 0.022
rna transport GO:0050658 2 0.022
negative regulation of signal transduction GO:0009968 94 0.022
cell proliferation GO:0008283 80 0.022
regulation of reproductive process GO:2000241 4 0.022
organic acid metabolic process GO:0006082 31 0.022
establishment of localization GO:0051234 244 0.022
rna polyadenylation GO:0043631 2 0.022
negative regulation of cell death GO:0060548 60 0.022
cellular amino acid metabolic process GO:0006520 7 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
regulation of binding GO:0051098 3 0.021
axon extension GO:0048675 45 0.021
cell migration GO:0016477 237 0.021
response to nutrient GO:0007584 3 0.021
cell projection morphogenesis GO:0048858 244 0.021
organism emergence from protective structure GO:0071684 4 0.021
immune system process GO:0002376 241 0.021
hindbrain development GO:0030902 91 0.021
regulation of protein localization to nucleus GO:1900180 2 0.020
sensory organ morphogenesis GO:0090596 200 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
taxis GO:0042330 109 0.020
response to abiotic stimulus GO:0009628 122 0.020
brain development GO:0007420 293 0.020
regulation of catalytic activity GO:0050790 55 0.020
amine metabolic process GO:0009308 2 0.019
rna export from nucleus GO:0006405 1 0.019
cellular component movement GO:0006928 335 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
blood circulation GO:0008015 87 0.019
stem cell maintenance GO:0019827 4 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.019
cellular amine metabolic process GO:0044106 2 0.019
single organism metabolic process GO:0044710 217 0.019
macromolecule localization GO:0033036 54 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
sexual reproduction GO:0019953 36 0.019
proteolysis GO:0006508 38 0.018
regulation of protein targeting GO:1903533 2 0.018
chromosome organization GO:0051276 31 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
cellular protein metabolic process GO:0044267 129 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
mrna polyadenylation GO:0006378 2 0.017
death GO:0016265 121 0.017
stem cell development GO:0048864 82 0.017
spliceosomal complex assembly GO:0000245 1 0.017
muscle organ development GO:0007517 101 0.017
transport GO:0006810 220 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
positive regulation of developmental process GO:0051094 50 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
reproduction GO:0000003 40 0.016
hemopoiesis GO:0030097 183 0.016
single organism cellular localization GO:1902580 46 0.016
regulation of apoptotic process GO:0042981 98 0.016
hepaticobiliary system development GO:0061008 98 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
regulation of cell development GO:0060284 100 0.016
neuron development GO:0048666 262 0.016
meiotic cell cycle process GO:1903046 3 0.016
wnt signaling pathway GO:0016055 80 0.016
multicellular organismal reproductive process GO:0048609 35 0.016
regulation of microtubule cytoskeleton organization GO:0070507 3 0.016
pancreas development GO:0031016 84 0.016
skeletal muscle organ development GO:0060538 78 0.016
negative regulation of kinase activity GO:0033673 4 0.016
growth plate cartilage development GO:0003417 2 0.016
blood vessel morphogenesis GO:0048514 216 0.016
regulation of cell proliferation GO:0042127 37 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
phagocytosis GO:0006909 3 0.015
positive regulation of mrna processing GO:0050685 1 0.015
multicellular organism reproduction GO:0032504 35 0.015
endoderm formation GO:0001706 29 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of programmed cell death GO:0043067 101 0.015
muscle structure development GO:0061061 196 0.015
embryonic heart tube development GO:0035050 133 0.015
translational initiation GO:0006413 3 0.015
male meiosis GO:0007140 2 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
segmentation GO:0035282 97 0.015
cellular response to biotic stimulus GO:0071216 3 0.014
lateral inhibition GO:0046331 1 0.014
cell part morphogenesis GO:0032990 246 0.014
protein stabilization GO:0050821 2 0.014
nucleic acid transport GO:0050657 2 0.014
formation of primary germ layer GO:0001704 62 0.014
dna biosynthetic process GO:0071897 3 0.014
cell cycle process GO:0022402 53 0.014
germ cell development GO:0007281 22 0.014
glucose homeostasis GO:0042593 1 0.014
regulation of cell cycle GO:0051726 52 0.014
negative regulation of translation GO:0017148 1 0.014
stem cell differentiation GO:0048863 117 0.014
carbohydrate homeostasis GO:0033500 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
mesoderm morphogenesis GO:0048332 51 0.014
somite development GO:0061053 96 0.014
cellular response to starvation GO:0009267 1 0.013
negative chemotaxis GO:0050919 1 0.013
cellular component assembly GO:0022607 170 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
regulation of protein metabolic process GO:0051246 56 0.013
growth GO:0040007 174 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
regulation of muscle contraction GO:0006937 3 0.013
determination of left right symmetry GO:0007368 179 0.013
negative regulation of rna metabolic process GO:0051253 48 0.013
negative regulation of myeloid cell differentiation GO:0045638 1 0.013
telomere organization GO:0032200 1 0.013
negative regulation of translational initiation GO:0045947 1 0.012
response to glucose GO:0009749 3 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
histone lysine demethylation GO:0070076 2 0.012
rna localization GO:0006403 4 0.012
heart process GO:0003015 71 0.012
protein modification process GO:0036211 100 0.012
protein localization GO:0008104 40 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of translational initiation GO:0006446 1 0.012
liver development GO:0001889 96 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
cell projection organization GO:0030030 284 0.012
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
primary neural tube formation GO:0014020 1 0.012
smooth muscle tissue development GO:0048745 1 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
regulation of organelle assembly GO:1902115 4 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
stem cell fate commitment GO:0048865 1 0.011
eye development GO:0001654 277 0.011
sympathetic nervous system development GO:0048485 3 0.011
sensory organ development GO:0007423 393 0.011
somatic cell dna recombination GO:0016444 1 0.011
positive regulation of rna splicing GO:0033120 1 0.011
chemical homeostasis GO:0048878 49 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
organelle organization GO:0006996 227 0.011
protein maturation GO:0051604 12 0.011
regulation of histone methylation GO:0031060 3 0.011
regulation of protein binding GO:0043393 3 0.011
spindle assembly GO:0051225 2 0.011
circulatory system process GO:0003013 87 0.011
positive regulation of signal transduction GO:0009967 56 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
response to corticosteroid GO:0031960 1 0.011
protein polyubiquitination GO:0000209 4 0.011
epithelial tube formation GO:0072175 19 0.011
cellular response to nutrient levels GO:0031669 2 0.011
striated muscle cell development GO:0055002 108 0.011
cellular protein modification process GO:0006464 100 0.011
spinal cord radial glial cell differentiation GO:0021531 2 0.011
positive regulation of transcription dna templated GO:0045893 57 0.010
axon development GO:0061564 166 0.010
neural crest cell development GO:0014032 62 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
microtubule based process GO:0007017 60 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.010
rna 3 end processing GO:0031123 2 0.010

zgc:136773 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.062
disease of cellular proliferation DOID:14566 0 0.062
organ system cancer DOID:0050686 0 0.062
disease of anatomical entity DOID:7 0 0.031
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
nervous system disease DOID:863 0 0.015