Danio rerio

25 known processes

fgf4

fibroblast growth factor 4

(Aliases: MGC158215)

fgf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chordate embryonic development GO:0043009 271 0.943
tube morphogenesis GO:0035239 349 0.864
otic vesicle morphogenesis GO:0071600 34 0.807
Zebrafish
neural tube development GO:0021915 62 0.750
locomotion GO:0040011 313 0.724
Zebrafish Worm
embryonic skeletal system development GO:0048706 97 0.721
connective tissue development GO:0061448 99 0.719
Human Zebrafish Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.675
cell surface receptor signaling pathway GO:0007166 325 0.670
Human Zebrafish Mouse Worm
endocrine system development GO:0035270 65 0.663
Zebrafish
neuron differentiation GO:0030182 353 0.654
Zebrafish Worm
cellular response to growth factor stimulus GO:0071363 39 0.648
Human Mouse Worm
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.634
Mouse
regulation of cell differentiation GO:0045595 142 0.625
Zebrafish Mouse Worm
determination of bilateral symmetry GO:0009855 204 0.621
determination of left right symmetry GO:0007368 179 0.605
cell motility GO:0048870 244 0.576
Zebrafish
kupffer s vesicle development GO:0070121 50 0.531
gastrulation GO:0007369 208 0.518
tissue remodeling GO:0048771 4 0.510
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.495
Human Mouse
response to organic substance GO:0010033 153 0.489
Human Mouse Worm
otic placode formation GO:0043049 23 0.475
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.464
Mouse
midbrain development GO:0030901 28 0.463
Zebrafish
appendage morphogenesis GO:0035107 56 0.447
Zebrafish Mouse
embryonic organ development GO:0048568 381 0.437
Zebrafish
response to endogenous stimulus GO:0009719 83 0.425
Human Mouse Worm
embryonic eye morphogenesis GO:0048048 30 0.408
head development GO:0060322 303 0.403
Zebrafish
cartilage development GO:0051216 96 0.400
Human Zebrafish Mouse
response to bacterium GO:0009617 58 0.392
cellular biosynthetic process GO:0044249 286 0.391
Mouse
negative regulation of cellular process GO:0048523 283 0.378
Zebrafish Mouse Worm
response to biotic stimulus GO:0009607 97 0.375
regulation of multicellular organismal development GO:2000026 223 0.374
Zebrafish Worm
regulation of multicellular organismal process GO:0051239 277 0.370
Zebrafish Worm
central nervous system development GO:0007417 387 0.365
Zebrafish
camera type eye development GO:0043010 222 0.364
Zebrafish
otic vesicle development GO:0071599 42 0.362
Zebrafish
striated muscle tissue development GO:0014706 110 0.358
cilium morphogenesis GO:0060271 85 0.357
cell projection morphogenesis GO:0048858 244 0.357
muscle structure development GO:0061061 196 0.355
homeostatic process GO:0042592 142 0.349
Zebrafish
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.346
Human Mouse Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.338
Mouse
axon guidance GO:0007411 86 0.327
Worm
negative regulation of cell cycle GO:0045786 14 0.327
aging GO:0007568 2 0.327
embryonic heart tube morphogenesis GO:0003143 108 0.324
pancreas development GO:0031016 84 0.323
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.317
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.316
response to chemical GO:0042221 320 0.303
Human Mouse Worm
somitogenesis GO:0001756 87 0.303
regulation of biosynthetic process GO:0009889 250 0.302
Mouse
kidney development GO:0001822 92 0.294
inner ear development GO:0048839 126 0.293
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.292
Zebrafish
cellular response to organic substance GO:0071310 105 0.284
Human Mouse Worm
positive regulation of rna biosynthetic process GO:1902680 57 0.281
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.280
Human Mouse Worm
mechanoreceptor differentiation GO:0042490 37 0.275
Zebrafish
odontogenesis of dentin containing tooth GO:0042475 1 0.269
Mouse
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.265
response to other organism GO:0051707 97 0.264
cellular nitrogen compound metabolic process GO:0034641 290 0.262
Mouse
ear development GO:0043583 127 0.259
Zebrafish
cellular component movement GO:0006928 335 0.256
Zebrafish Worm
positive regulation of metabolic process GO:0009893 108 0.254
Human Mouse
sensory organ morphogenesis GO:0090596 200 0.250
Zebrafish
cellular response to endogenous stimulus GO:0071495 68 0.246
Human Mouse Worm
single organism metabolic process GO:0044710 217 0.245
Human
heart development GO:0007507 313 0.245
regulation of developmental process GO:0050793 247 0.241
Zebrafish Mouse Worm
axonogenesis GO:0007409 152 0.236
Worm
larval development GO:0002164 2 0.235
Worm
muscle tissue development GO:0060537 110 0.228
ear morphogenesis GO:0042471 64 0.226
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.226
Mouse
skin development GO:0043588 54 0.223
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.223
regulation of autophagy GO:0010506 3 0.222
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.218
Worm
sensory organ development GO:0007423 393 0.216
Zebrafish
regulation of response to stimulus GO:0048583 269 0.215
Human Zebrafish Worm
embryonic camera type eye development GO:0031076 29 0.214
regulation of phospholipase c activity GO:1900274 1 0.210
adenohypophysis development GO:0021984 15 0.209
Zebrafish
cell fate specification GO:0001708 68 0.208
Zebrafish
response to external stimulus GO:0009605 264 0.207
Worm
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.205
digestive tract morphogenesis GO:0048546 231 0.201
wound healing GO:0042060 90 0.200
Zebrafish
response to growth factor GO:0070848 39 0.199
Human Mouse Worm
nucleic acid metabolic process GO:0090304 244 0.197
Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.197
Zebrafish
regulation of axonogenesis GO:0050770 32 0.196
Worm
positive regulation of cellular biosynthetic process GO:0031328 68 0.189
Mouse
odontogenesis GO:0042476 9 0.189
Mouse
hindbrain development GO:0030902 91 0.186
Zebrafish
cell migration involved in gastrulation GO:0042074 79 0.184
cell projection organization GO:0030030 284 0.183
t cell differentiation GO:0030217 6 0.182
regulation of cell communication GO:0010646 232 0.181
Human Zebrafish
epithelial cell differentiation GO:0030855 116 0.180
Zebrafish
skeletal system development GO:0001501 181 0.177
Human Zebrafish Mouse
skeletal system morphogenesis GO:0048705 102 0.175
Mouse
localization of cell GO:0051674 244 0.175
Zebrafish
lateral line development GO:0048882 66 0.174
Zebrafish
immune system process GO:0002376 241 0.173
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.173
Zebrafish
regulation of cell cycle GO:0051726 52 0.172
embryonic neurocranium morphogenesis GO:0048702 15 0.172
muscle cell differentiation GO:0042692 139 0.170
defense response to other organism GO:0098542 33 0.168
regulation of nitrogen compound metabolic process GO:0051171 251 0.166
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.164
Mouse
gland development GO:0048732 143 0.160
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.158
Worm
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.157
regulation of cellular biosynthetic process GO:0031326 245 0.156
Mouse
positive regulation of gene expression GO:0010628 71 0.156
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.154
Human
ameboidal type cell migration GO:0001667 143 0.153
stem cell proliferation GO:0072089 4 0.152
Human
generation of neurons GO:0048699 385 0.150
Zebrafish Worm
fin regeneration GO:0031101 51 0.148
Zebrafish
stem cell maintenance GO:0019827 4 0.145
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.144
Zebrafish
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.143
embryonic viscerocranium morphogenesis GO:0048703 52 0.143
positive regulation of cell migration GO:0030335 11 0.142
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.142
Mouse
spinal cord anterior posterior patterning GO:0021512 1 0.139
positive regulation of biosynthetic process GO:0009891 68 0.138
Mouse
cellular response to chemical stimulus GO:0070887 157 0.137
Human Mouse Worm
rna biosynthetic process GO:0032774 181 0.134
Mouse
cellular carbohydrate metabolic process GO:0044262 4 0.134
dorsal ventral pattern formation GO:0009953 125 0.134
Zebrafish
digestive system development GO:0055123 289 0.133
signal transduction GO:0007165 455 0.132
Human Zebrafish Mouse Worm
central nervous system neuron differentiation GO:0021953 74 0.132
optic placode formation involved in camera type eye formation GO:0046619 3 0.132
organic cyclic compound metabolic process GO:1901360 301 0.129
Mouse
cell migration GO:0016477 237 0.128
Zebrafish
oligodendrocyte differentiation GO:0048709 23 0.126
Zebrafish
death GO:0016265 121 0.125
Zebrafish Mouse
positive regulation of transcription dna templated GO:0045893 57 0.123
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.122
cardiac muscle tissue development GO:0048738 48 0.122
negative regulation of apoptotic process GO:0043066 55 0.121
Zebrafish Mouse
regulation of cell morphogenesis GO:0022604 42 0.119
Worm
actin filament based process GO:0030029 64 0.118
cell death GO:0008219 121 0.118
Zebrafish Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.116
positive regulation of response to stimulus GO:0048584 80 0.116
Human Zebrafish
neuron development GO:0048666 262 0.116
Zebrafish Worm
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.115
biosynthetic process GO:0009058 294 0.114
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.113
Mouse
regulation of locomotion GO:0040012 55 0.113
Zebrafish Worm
transcription from rna polymerase ii promoter GO:0006366 80 0.113
Mouse
lymphocyte differentiation GO:0030098 9 0.112
nucleic acid templated transcription GO:0097659 181 0.112
Mouse
lateral line system development GO:0048925 76 0.111
Zebrafish
maintenance of location GO:0051235 4 0.111
embryo development ending in birth or egg hatching GO:0009792 271 0.108
oxidation reduction process GO:0055114 41 0.108
regulation of cell proliferation GO:0042127 37 0.107
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.106
positive regulation of biological process GO:0048518 253 0.105
Human Zebrafish Mouse
multi organism process GO:0051704 134 0.105
eye development GO:0001654 277 0.104
Zebrafish
axon development GO:0061564 166 0.104
Worm
embryonic camera type eye morphogenesis GO:0048596 19 0.104
negative regulation of metabolic process GO:0009892 86 0.103
rna metabolic process GO:0016070 219 0.103
Mouse
periodic partitioning GO:0007365 1 0.103
bmp signaling pathway involved in heart jogging GO:0003303 14 0.100
positive regulation of cellular process GO:0048522 201 0.100
Human Zebrafish Mouse
stem cell development GO:0048864 82 0.099
Mouse
rhombomere 5 development GO:0021571 4 0.099
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.099
cell fate commitment GO:0045165 99 0.098
Zebrafish
gall bladder development GO:0061010 1 0.097
intracellular signal transduction GO:0035556 85 0.096
Human
peptidyl lysine acetylation GO:0018394 2 0.095
thrombocyte differentiation GO:0002574 4 0.094
cell morphogenesis GO:0000902 289 0.094
inner ear morphogenesis GO:0042472 63 0.094
Zebrafish
autophagy GO:0006914 4 0.093
ossification GO:0001503 23 0.093
striated muscle cell differentiation GO:0051146 129 0.092
carbohydrate derivative metabolic process GO:1901135 61 0.091
urogenital system development GO:0001655 97 0.091
regionalization GO:0003002 274 0.089
Zebrafish
sensory perception of smell GO:0007608 2 0.088
regulation of axon extension involved in axon guidance GO:0048841 6 0.088
Worm
regulation of neuron projection development GO:0010975 40 0.086
Worm
pigmentation GO:0043473 85 0.086
negative regulation of mitosis GO:0045839 3 0.085
nucleobase containing compound biosynthetic process GO:0034654 205 0.085
Mouse
chemosensory behavior GO:0007635 1 0.084
anterior head development GO:0097065 2 0.083
nucleobase containing compound metabolic process GO:0006139 274 0.083
Mouse
regulation of anterior head development GO:2000742 2 0.083
renal system development GO:0072001 94 0.082
determination of heart left right asymmetry GO:0061371 117 0.082
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.081
Mouse
regulation of dna replication GO:0006275 3 0.081
response to fibroblast growth factor GO:0071774 22 0.081
Human Mouse Worm
cell part morphogenesis GO:0032990 246 0.081
positive regulation of cellular component movement GO:0051272 11 0.080
Zebrafish
organ formation GO:0048645 17 0.080
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.080
Worm
pectoral fin morphogenesis GO:0035138 29 0.079
Zebrafish
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.078
response to stress GO:0006950 263 0.078
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.078
Worm
specification of symmetry GO:0009799 204 0.076
hepatocyte proliferation GO:0072574 2 0.075
heart morphogenesis GO:0003007 156 0.075
metencephalon development GO:0022037 27 0.073
Zebrafish
mesoderm development GO:0007498 88 0.073
hepatic duct development GO:0061011 2 0.072
convergent extension involved in gastrulation GO:0060027 71 0.072
pericardium development GO:0060039 1 0.071
bmp signaling pathway involved in heart development GO:0061312 15 0.071
taxis GO:0042330 109 0.070
Worm
craniofacial suture morphogenesis GO:0097094 2 0.070
Mouse
organic substance biosynthetic process GO:1901576 289 0.070
Mouse
anatomical structure homeostasis GO:0060249 36 0.069
Zebrafish
response to xenobiotic stimulus GO:0009410 45 0.069
regulation of cell death GO:0010941 103 0.069
Zebrafish Mouse
negative regulation of muscle tissue development GO:1901862 2 0.069
apoptotic process GO:0006915 116 0.069
Zebrafish Mouse
segment polarity determination GO:0007367 1 0.068
negative regulation of feeding behavior GO:2000252 2 0.068
regulation of cellular response to growth factor stimulus GO:0090287 35 0.067
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.066
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.066
Mouse
negative regulation of muscle organ development GO:0048635 5 0.065
pectoral fin development GO:0033339 50 0.065
Zebrafish
segmentation GO:0035282 97 0.065
regulation of rna biosynthetic process GO:2001141 213 0.065
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.064
Mouse
mesenchyme development GO:0060485 127 0.064
regulation of signal transduction GO:0009966 225 0.064
Human Zebrafish
regulation of metabolic process GO:0019222 359 0.063
Human Mouse
tissue regeneration GO:0042246 74 0.063
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.061
Zebrafish
cellular hormone metabolic process GO:0034754 19 0.061
regulation of cellular component movement GO:0051270 55 0.061
Zebrafish Worm
blood vessel morphogenesis GO:0048514 216 0.061
regulation of organ growth GO:0046620 3 0.061
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.059
Human Mouse Worm
regulation of stem cell differentiation GO:2000736 4 0.059
positive regulation of transport GO:0051050 2 0.059
negative regulation of kinase activity GO:0033673 4 0.058
ectodermal placode morphogenesis GO:0071697 32 0.058
Zebrafish
stem cell differentiation GO:0048863 117 0.058
Mouse
morphogenesis of embryonic epithelium GO:0016331 30 0.058
embryonic camera type eye formation GO:0060900 10 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.057
positive regulation of cellular catabolic process GO:0031331 3 0.057
striated muscle cell development GO:0055002 108 0.057
heterocycle metabolic process GO:0046483 290 0.056
Mouse
notochord development GO:0030903 54 0.056
endocardial cushion formation GO:0003272 2 0.055
regulation of molecular function GO:0065009 70 0.055
aromatic compound biosynthetic process GO:0019438 217 0.055
Mouse
nucleocytoplasmic transport GO:0006913 4 0.055
regulation of tube size GO:0035150 2 0.054
negative regulation of striated muscle tissue development GO:0045843 2 0.054
eye morphogenesis GO:0048592 144 0.054
Zebrafish
neural tube patterning GO:0021532 33 0.053
regulation of programmed cell death GO:0043067 101 0.053
Zebrafish Mouse
small molecule metabolic process GO:0044281 77 0.052
regulation of macromolecule metabolic process GO:0060255 317 0.052
Mouse
hair cell differentiation GO:0035315 32 0.052
Zebrafish
neurological system process GO:0050877 62 0.051
neuron projection development GO:0031175 180 0.051
Worm
regulation of cell size GO:0008361 29 0.051
Worm
positive regulation of catabolic process GO:0009896 4 0.051
somite development GO:0061053 96 0.050
neural plate development GO:0001840 10 0.050
response to abiotic stimulus GO:0009628 122 0.050
pronephros development GO:0048793 69 0.050
modification dependent protein catabolic process GO:0019941 3 0.050
optic placode formation GO:0001743 4 0.050
regulation of response to nutrient levels GO:0032107 1 0.049
post anal tail morphogenesis GO:0036342 19 0.049
sensory perception of chemical stimulus GO:0007606 3 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.049
Human Mouse Worm
positive regulation of cell communication GO:0010647 56 0.048
Human Zebrafish
transport GO:0006810 220 0.048
single organism biosynthetic process GO:0044711 71 0.048
t cell activation GO:0042110 6 0.048
epithelial tube morphogenesis GO:0060562 148 0.047
negative regulation of biological process GO:0048519 304 0.047
Zebrafish Mouse Worm
digestive tract development GO:0048565 265 0.047
programmed cell death GO:0012501 119 0.047
Zebrafish Mouse
negative regulation of gene expression GO:0010629 65 0.046
locus ceruleus development GO:0021703 3 0.046
Zebrafish
embryonic pattern specification GO:0009880 44 0.046
Zebrafish
hard palate development GO:0060022 4 0.046
Zebrafish
epithelial to mesenchymal transition GO:0001837 21 0.045
stem cell division GO:0017145 1 0.045
positive regulation of apoptotic process GO:0043065 29 0.045
regulation of organ morphogenesis GO:2000027 35 0.044
exocrine system development GO:0035272 28 0.044
negative regulation of programmed cell death GO:0043069 58 0.044
Zebrafish Mouse
embryonic digestive tract morphogenesis GO:0048557 3 0.044
mediolateral intercalation GO:0060031 3 0.044
regulation of stem cell proliferation GO:0072091 2 0.043
gene expression GO:0010467 252 0.042
Mouse
response to external biotic stimulus GO:0043207 97 0.042
sensory system development GO:0048880 76 0.042
Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.041
brain development GO:0007420 293 0.041
Zebrafish
heart looping GO:0001947 94 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.041
Mouse
rostrocaudal neural tube patterning GO:0021903 29 0.041
forebrain regionalization GO:0021871 4 0.041
macromolecule modification GO:0043412 111 0.040
Mouse
pons development GO:0021548 11 0.040
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.040
regulation of circadian rhythm GO:0042752 4 0.040
regulation of heart morphogenesis GO:2000826 17 0.040
regulation of apoptotic process GO:0042981 98 0.040
Zebrafish Mouse
alcohol biosynthetic process GO:0046165 2 0.040
regulation of nuclear division GO:0051783 9 0.039
regulation of signaling GO:0023051 235 0.038
Human Zebrafish
camera type eye morphogenesis GO:0048593 108 0.038
Zebrafish
fin morphogenesis GO:0033334 53 0.038
Zebrafish
otolith development GO:0048840 32 0.038
Zebrafish
response to wounding GO:0009611 116 0.038
Zebrafish
hemopoiesis GO:0030097 183 0.038
Zebrafish
regulation of cartilage development GO:0061035 7 0.038
fin development GO:0033333 77 0.038
Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.037
transcription dna templated GO:0006351 181 0.037
Mouse
regulation of cell fate specification GO:0042659 20 0.037
inner ear receptor cell differentiation GO:0060113 29 0.037
Zebrafish
heart contraction GO:0060047 71 0.037
positive regulation of multicellular organismal process GO:0051240 52 0.036
Zebrafish
bone remodeling GO:0046849 2 0.036
Zebrafish
positive regulation of muscle tissue development GO:1901863 1 0.036
retina morphogenesis in camera type eye GO:0060042 79 0.036
Zebrafish
circadian sleep wake cycle sleep GO:0050802 1 0.036
cell differentiation in spinal cord GO:0021515 40 0.036
positive regulation of rna metabolic process GO:0051254 59 0.035
Mouse
carbohydrate metabolic process GO:0005975 12 0.035
protein import into nucleus GO:0006606 3 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
Mouse
ectodermal placode development GO:0071696 37 0.035
Zebrafish
regulation of insulin like growth factor receptor signaling pathway GO:0043567 1 0.035
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.034
cell substrate adhesion GO:0031589 4 0.034
regulation of cell motility GO:2000145 46 0.034
Zebrafish
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
positive regulation of cell activation GO:0050867 1 0.033
developmental growth GO:0048589 166 0.033
Zebrafish Worm
cellular response to external stimulus GO:0071496 2 0.033
chondrocyte differentiation GO:0002062 7 0.033
regulation of cell development GO:0060284 100 0.033
Zebrafish Worm
regulation of binding GO:0051098 3 0.033
cellular macromolecule metabolic process GO:0044260 391 0.033
Mouse
otic vesicle formation GO:0030916 27 0.033
Zebrafish
positive regulation of cell division GO:0051781 2 0.033
hormone biosynthetic process GO:0042446 3 0.033
regulation of biological quality GO:0065008 263 0.032
Zebrafish Worm
regulation of cardiac muscle tissue development GO:0055024 1 0.032
cellular localization GO:0051641 97 0.032
cellular response to hypoxia GO:0071456 1 0.032
single organism reproductive process GO:0044702 40 0.032
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.032
sensory perception of mechanical stimulus GO:0050954 16 0.032
single organism organelle organization GO:1902589 199 0.031
negative regulation of cell migration GO:0030336 17 0.031
apoptotic process involved in morphogenesis GO:0060561 2 0.031
Mouse
diencephalon development GO:0021536 58 0.031
Zebrafish
regulation of axon extension GO:0030516 24 0.031
Worm
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.031
regulation of extent of cell growth GO:0061387 29 0.031
Worm
sensory perception of sound GO:0007605 9 0.030
positive regulation of protein kinase b signaling GO:0051897 1 0.030
developmental growth involved in morphogenesis GO:0060560 86 0.030
Worm
internal peptidyl lysine acetylation GO:0018393 2 0.029
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.029
carbohydrate biosynthetic process GO:0016051 1 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
Mouse
regulation of protein ubiquitination GO:0031396 3 0.029
sensory perception GO:0007600 39 0.029
morphogenesis of an epithelial fold GO:0060571 1 0.029
regulation of carbohydrate metabolic process GO:0006109 4 0.029
positive regulation of cell differentiation GO:0045597 30 0.029
Zebrafish
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.029
multicellular organism growth GO:0035264 4 0.028
cellular response to hormone stimulus GO:0032870 39 0.028
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.028
positive regulation of nucleic acid templated transcription GO:1903508 57 0.028
Mouse
regulation of heart growth GO:0060420 2 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
negative regulation of cell death GO:0060548 60 0.027
Zebrafish Mouse
epidermal cell differentiation GO:0009913 36 0.027
Zebrafish
female sex differentiation GO:0046660 4 0.027
neuroblast proliferation GO:0007405 2 0.027
insulin like growth factor receptor signaling pathway GO:0048009 4 0.027
nuclear transport GO:0051169 4 0.027
regulation of cell activation GO:0050865 1 0.027
regulation of primary metabolic process GO:0080090 311 0.026
Mouse
regulation of mitosis GO:0007088 9 0.026
regulation of immune system process GO:0002682 34 0.026
cell cell signaling involved in cell fate commitment GO:0045168 12 0.026
embryonic appendage morphogenesis GO:0035113 30 0.026
Zebrafish Mouse
cellular biogenic amine metabolic process GO:0006576 2 0.026
regulation of mesoderm development GO:2000380 11 0.026
regulation of cytokine production GO:0001817 3 0.026
midbrain hindbrain boundary development GO:0030917 23 0.025
embryonic limb morphogenesis GO:0030326 2 0.025
Mouse
vestibular receptor cell differentiation GO:0060114 3 0.025
Zebrafish
cytoskeleton organization GO:0007010 96 0.025
organ growth GO:0035265 12 0.025
neuron projection morphogenesis GO:0048812 161 0.025
Worm
mesenchyme morphogenesis GO:0072132 5 0.025
negative regulation of signal transduction GO:0009968 94 0.025
embryonic skeletal joint development GO:0072498 3 0.024
peptidyl lysine methylation GO:0018022 3 0.024
blood circulation GO:0008015 87 0.024
apoptotic process involved in development GO:1902742 2 0.024
Mouse
specification of organ identity GO:0010092 2 0.024
regulation of neuron differentiation GO:0045664 56 0.024
Zebrafish Worm
neuroblast differentiation GO:0014016 1 0.024
cell cycle GO:0007049 93 0.024
single organism localization GO:1902578 225 0.024
regulation of neurogenesis GO:0050767 87 0.024
Zebrafish Worm
steroid hormone mediated signaling pathway GO:0043401 9 0.024
cell proliferation GO:0008283 80 0.023
Human Zebrafish Mouse
endoderm development GO:0007492 49 0.023
ketone biosynthetic process GO:0042181 2 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
Human Mouse
microtubule cytoskeleton organization GO:0000226 33 0.023
developmental induction GO:0031128 10 0.023
sexual reproduction GO:0019953 36 0.023
positive regulation of stem cell proliferation GO:2000648 1 0.023
negative regulation of cellular biosynthetic process GO:0031327 55 0.023
tube closure GO:0060606 1 0.023
semicircular canal formation GO:0060876 4 0.022
protein acetylation GO:0006473 2 0.022
limb morphogenesis GO:0035108 7 0.022
Mouse
cell growth GO:0016049 57 0.022
Worm
regulation of bone mineralization GO:0030500 2 0.022
establishment of localization GO:0051234 244 0.022
spemann organizer formation GO:0060061 10 0.022
regulation of epithelial to mesenchymal transition GO:0010717 3 0.022
protein kinase b signaling GO:0043491 9 0.022
axon extension GO:0048675 45 0.022
Worm
embryonic heart tube development GO:0035050 133 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
lipid storage GO:0019915 1 0.022
signal transduction in absence of ligand GO:0038034 1 0.022
regulation of rna metabolic process GO:0051252 224 0.022
Mouse
pharyngeal system development GO:0060037 18 0.022
regulation of embryonic development GO:0045995 47 0.022
positive regulation of cell motility GO:2000147 11 0.022
Zebrafish
hepaticobiliary system development GO:0061008 98 0.021
Zebrafish
intracellular transport GO:0046907 32 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
Mouse
compound eye development GO:0048749 2 0.021
cellular response to steroid hormone stimulus GO:0071383 31 0.021
single organism transport GO:0044765 206 0.021
defense response to bacterium GO:0042742 22 0.021
endocardial cushion morphogenesis GO:0003203 3 0.021
regulation of protein complex assembly GO:0043254 3 0.021
positive regulation of molecular function GO:0044093 33 0.021
positive regulation of cell adhesion GO:0045785 1 0.021
defense response GO:0006952 47 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
liver development GO:0001889 96 0.020
Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.020
Mouse
nephron development GO:0072006 31 0.020
angiogenesis GO:0001525 158 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
regulation of endodermal cell fate specification GO:0042663 15 0.020
fatty acid oxidation GO:0019395 1 0.020
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.020
regulation of catalytic activity GO:0050790 55 0.020

fgf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.082
musculoskeletal system disease DOID:17 0 0.082
bone development disease DOID:0080006 0 0.038
bone disease DOID:0080001 0 0.038
connective tissue disease DOID:65 0 0.038