Danio rerio

6 known processes

fgf2

fibroblast growth factor 2

fgf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.098
cellular protein catabolic process GO:0044257 4 0.093
negative regulation of biological process GO:0048519 304 0.078
signal transduction GO:0007165 455 0.071
nitrogen compound metabolic process GO:0006807 319 0.071
morphogenesis of an epithelium GO:0002009 333 0.071
regulation of response to stimulus GO:0048583 269 0.070
digestive tract development GO:0048565 265 0.068
central nervous system development GO:0007417 387 0.065
cellular macromolecule metabolic process GO:0044260 391 0.060
regulation of protein transport GO:0051223 3 0.059
regulation of establishment of protein localization GO:0070201 4 0.057
cell morphogenesis GO:0000902 289 0.053
negative regulation of protein phosphorylation GO:0001933 4 0.053
aging GO:0007568 2 0.053
cilium movement GO:0003341 26 0.050
macromolecule biosynthetic process GO:0009059 227 0.048
determination of bilateral symmetry GO:0009855 204 0.047
regulation of multicellular organism growth GO:0040014 4 0.045
regulation of signal transduction GO:0009966 225 0.045
cell surface receptor signaling pathway GO:0007166 325 0.045
regulation of macromolecule metabolic process GO:0060255 317 0.044
establishment of localization GO:0051234 244 0.043
regulation of cytokine production GO:0001817 3 0.043
organic cyclic compound biosynthetic process GO:1901362 223 0.042
nucleocytoplasmic transport GO:0006913 4 0.042
regulation of cell communication GO:0010646 232 0.041
microtubule based movement GO:0007018 33 0.040
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
biosynthetic process GO:0009058 294 0.038
protein import GO:0017038 3 0.038
organic substance biosynthetic process GO:1901576 289 0.037
positive regulation of catabolic process GO:0009896 4 0.036
cellular biosynthetic process GO:0044249 286 0.036
gene expression GO:0010467 252 0.035
nuclear transport GO:0051169 4 0.034
digestive system development GO:0055123 289 0.034
regulation of metabolic process GO:0019222 359 0.034
heterocycle biosynthetic process GO:0018130 215 0.033
digestive tract morphogenesis GO:0048546 231 0.033
regulation of cell shape GO:0008360 1 0.033
multicellular organism growth GO:0035264 4 0.033
regulation of synapse organization GO:0050807 3 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.032
single organism organelle organization GO:1902589 199 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
tube morphogenesis GO:0035239 349 0.032
regulation of signaling GO:0023051 235 0.032
cell projection morphogenesis GO:0048858 244 0.031
rna metabolic process GO:0016070 219 0.031
erk1 and erk2 cascade GO:0070371 4 0.031
determination of left right symmetry GO:0007368 179 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
regulation of developmental process GO:0050793 247 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.030
regulation of biological quality GO:0065008 263 0.030
oxoacid metabolic process GO:0043436 31 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
positive regulation of transport GO:0051050 2 0.030
cellular amine metabolic process GO:0044106 2 0.030
macromolecule modification GO:0043412 111 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
cellular component movement GO:0006928 335 0.029
specification of symmetry GO:0009799 204 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
regulation of rna biosynthetic process GO:2001141 213 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
compound eye development GO:0048749 2 0.028
organic acid metabolic process GO:0006082 31 0.028
maintenance of location GO:0051235 4 0.028
regulation of gene expression GO:0010468 265 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
response to chemical GO:0042221 320 0.028
negative regulation of protein transport GO:0051224 3 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
negative regulation of cellular process GO:0048523 283 0.028
single organism nuclear import GO:1902593 3 0.027
protein targeting to nucleus GO:0044744 3 0.027
muscle cell development GO:0055001 115 0.027
aromatic compound biosynthetic process GO:0019438 217 0.027
gastrulation GO:0007369 208 0.027
nuclear import GO:0051170 3 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
embryonic organ development GO:0048568 381 0.026
cellular protein modification process GO:0006464 100 0.026
organelle organization GO:0006996 227 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
death GO:0016265 121 0.026
proteasomal protein catabolic process GO:0010498 2 0.026
cilium morphogenesis GO:0060271 85 0.026
regulation of primary metabolic process GO:0080090 311 0.026
amine metabolic process GO:0009308 2 0.026
actin filament based movement GO:0030048 1 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
chordate embryonic development GO:0043009 271 0.026
generation of neurons GO:0048699 385 0.026
cellular ketone metabolic process GO:0042180 11 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
cellular component morphogenesis GO:0032989 336 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
regulation of protein targeting GO:1903533 2 0.025
single organism transport GO:0044765 206 0.025
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.025
protein metabolic process GO:0019538 183 0.025
regulation of protein localization to nucleus GO:1900180 2 0.025
phagocytosis GO:0006909 3 0.025
heterocycle metabolic process GO:0046483 290 0.024
positive regulation of biological process GO:0048518 253 0.024
nucleic acid metabolic process GO:0090304 244 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
cell part morphogenesis GO:0032990 246 0.024
protein acetylation GO:0006473 2 0.024
regulation of protein catabolic process GO:0042176 1 0.023
regulation of cell differentiation GO:0045595 142 0.023
locomotion GO:0040011 313 0.023
single organism metabolic process GO:0044710 217 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
developmental growth GO:0048589 166 0.023
striated muscle cell differentiation GO:0051146 129 0.023
small molecule metabolic process GO:0044281 77 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
protein import into nucleus GO:0006606 3 0.023
regulation of rna metabolic process GO:0051252 224 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
protein localization to nucleus GO:0034504 3 0.022
transport GO:0006810 220 0.022
muscle tissue development GO:0060537 110 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
apoptotic process GO:0006915 116 0.022
cell death GO:0008219 121 0.022
protein modification process GO:0036211 100 0.022
regulation of synapse assembly GO:0051963 3 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
cilium organization GO:0044782 71 0.021
single organism localization GO:1902578 225 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of cell development GO:0060284 100 0.021
golgi vesicle transport GO:0048193 3 0.021
stem cell proliferation GO:0072089 4 0.021
meiotic nuclear division GO:0007126 4 0.021
gtp catabolic process GO:0006184 2 0.020
response to stress GO:0006950 263 0.020
immune system process GO:0002376 241 0.020
cellular protein metabolic process GO:0044267 129 0.020
cell substrate adhesion GO:0031589 4 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
transcription dna templated GO:0006351 181 0.020
carbohydrate derivative biosynthetic process GO:1901137 43 0.020
blood vessel morphogenesis GO:0048514 216 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
specification of axis polarity GO:0065001 4 0.020
regulation of biosynthetic process GO:0009889 250 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
adult behavior GO:0030534 2 0.019
axonogenesis GO:0007409 152 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
nucleic acid templated transcription GO:0097659 181 0.019
meiotic cell cycle process GO:1903046 3 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
cellular component disassembly GO:0022411 1 0.018
brain development GO:0007420 293 0.018
rna biosynthetic process GO:0032774 181 0.018
muscle structure development GO:0061061 196 0.018
cognition GO:0050890 1 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
organelle assembly GO:0070925 110 0.018
cell matrix adhesion GO:0007160 4 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
female meiotic division GO:0007143 2 0.018
positive regulation of cell cycle GO:0045787 3 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
cellular component biogenesis GO:0044085 178 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
convergent extension GO:0060026 118 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
regulation of transcription dna templated GO:0006355 213 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
programmed cell death GO:0012501 119 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
sensory organ development GO:0007423 393 0.017
cell projection organization GO:0030030 284 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
response to uv GO:0009411 3 0.017
negative regulation of kinase activity GO:0033673 4 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
striated muscle tissue development GO:0014706 110 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
wnt signaling pathway GO:0016055 80 0.016
cell migration GO:0016477 237 0.016
negative regulation of cytoplasmic transport GO:1903650 2 0.016
leukocyte proliferation GO:0070661 1 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
regulation of metal ion transport GO:0010959 4 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
autophagy GO:0006914 4 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.015
regulation of cell death GO:0010941 103 0.015
protein complex disassembly GO:0043241 1 0.015
gtp metabolic process GO:0046039 4 0.015
centrosome organization GO:0051297 1 0.015
g protein coupled receptor signaling pathway GO:0007186 74 0.015
striated muscle cell development GO:0055002 108 0.015
blood vessel development GO:0001568 246 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
protein localization to plasma membrane GO:0072659 1 0.015
protein secretion GO:0009306 1 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
localization of cell GO:0051674 244 0.015
neurological system process GO:0050877 62 0.014
microtubule organizing center organization GO:0031023 1 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
heart development GO:0007507 313 0.014
system process GO:0003008 185 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
nuclear migration GO:0007097 3 0.014
regulation of dna replication GO:0006275 3 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
regulation of transporter activity GO:0032409 2 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
regulation of binding GO:0051098 3 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of apoptotic process GO:0042981 98 0.014
cell motility GO:0048870 244 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
regulation of gtpase activity GO:0043087 2 0.014
membrane invagination GO:0010324 1 0.014
macromolecular complex disassembly GO:0032984 1 0.014
embryonic heart tube development GO:0035050 133 0.014
multicellular organismal signaling GO:0035637 22 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
phagocytosis engulfment GO:0006911 1 0.014
regulation of autophagy GO:0010506 3 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.013
protein stabilization GO:0050821 2 0.013
peptidyl serine modification GO:0018209 2 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
positive regulation of cytokine production GO:0001819 2 0.013
protein dephosphorylation GO:0006470 3 0.013
lipid storage GO:0019915 1 0.013
head development GO:0060322 303 0.013
cellular response to organic substance GO:0071310 105 0.013
response to abiotic stimulus GO:0009628 122 0.013
neuron projection morphogenesis GO:0048812 161 0.013
glycoprotein biosynthetic process GO:0009101 21 0.013
protein homooligomerization GO:0051260 3 0.013
regulation of neurogenesis GO:0050767 87 0.013
regulation of dendrite development GO:0050773 3 0.013
response to carbohydrate GO:0009743 3 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
adherens junction organization GO:0034332 4 0.013
actin mediated cell contraction GO:0070252 1 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
ras protein signal transduction GO:0007265 7 0.012
vasculature development GO:0001944 278 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
muscle cell differentiation GO:0042692 139 0.012
positive regulation of ras protein signal transduction GO:0046579 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
growth GO:0040007 174 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
regionalization GO:0003002 274 0.012
glycoprotein metabolic process GO:0009100 23 0.012
sarcomere organization GO:0045214 26 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
negative regulation of signaling GO:0023057 96 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
microtubule based process GO:0007017 60 0.012
neuron development GO:0048666 262 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
negative regulation of metabolic process GO:0009892 86 0.011
protein polyubiquitination GO:0000209 4 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
neuroblast proliferation GO:0007405 2 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
protein acylation GO:0043543 3 0.011
sensory perception of smell GO:0007608 2 0.011
mitochondrion organization GO:0007005 4 0.011
cellular response to radiation GO:0071478 4 0.011
muscle fiber development GO:0048747 52 0.011
ameboidal type cell migration GO:0001667 143 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
intracellular signal transduction GO:0035556 85 0.011
cellular component assembly GO:0022607 170 0.011
calcium ion import GO:0070509 4 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
action potential GO:0001508 19 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
cardiac atrium development GO:0003230 4 0.011
negative regulation of cell death GO:0060548 60 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
regulation of cell activation GO:0050865 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
small molecule catabolic process GO:0044282 3 0.011
phototransduction GO:0007602 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
skeletal system development GO:0001501 181 0.011
cellular response to external stimulus GO:0071496 2 0.011
stem cell maintenance GO:0019827 4 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
response to organic substance GO:0010033 153 0.011
negative regulation of cytokine production GO:0001818 1 0.011
fertilization GO:0009566 3 0.011
regulation of localization GO:0032879 104 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
cell substrate junction assembly GO:0007044 2 0.011
negative regulation of gene expression GO:0010629 65 0.011
lymphocyte proliferation GO:0046651 1 0.011
negative regulation of catabolic process GO:0009895 3 0.010
regulation of myotube differentiation GO:0010830 2 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
kupffer s vesicle development GO:0070121 50 0.010
regulation of receptor activity GO:0010469 2 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
stem cell division GO:0017145 1 0.010
phosphorus metabolic process GO:0006793 109 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
neuron differentiation GO:0030182 353 0.010
anterior posterior pattern specification GO:0009952 152 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
positive regulation of secretion GO:0051047 1 0.010

fgf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011