Danio rerio

0 known processes

idh3a

isocitrate dehydrogenase 3 (NAD+) alpha

(Aliases: MGC56380,zgc:85631,zgc:56380)

idh3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.398
Worm
oxoacid metabolic process GO:0043436 31 0.207
Yeast Rat
larval development GO:0002164 2 0.175
organic acid metabolic process GO:0006082 31 0.163
Yeast Rat
single organism metabolic process GO:0044710 217 0.159
Yeast Rat
organonitrogen compound metabolic process GO:1901564 74 0.120
Rat
dicarboxylic acid metabolic process GO:0043648 1 0.113
Rat
carboxylic acid metabolic process GO:0019752 22 0.096
Yeast Rat
regulation of developmental process GO:0050793 247 0.094
alpha amino acid metabolic process GO:1901605 3 0.091
digestive tract development GO:0048565 265 0.085
small molecule metabolic process GO:0044281 77 0.084
Yeast Rat
cellular respiration GO:0045333 3 0.082
Rat
pyruvate metabolic process GO:0006090 1 0.082
respiratory electron transport chain GO:0022904 2 0.075
oxidation reduction process GO:0055114 41 0.071
Yeast Rat
nitrogen compound metabolic process GO:0006807 319 0.068
Rat
organic substance biosynthetic process GO:1901576 289 0.060
ribonucleoside monophosphate catabolic process GO:0009158 4 0.059
negative regulation of cellular process GO:0048523 283 0.059
negative regulation of kinase activity GO:0033673 4 0.058
cell part morphogenesis GO:0032990 246 0.058
response to chemical GO:0042221 320 0.057
signal transduction GO:0007165 455 0.057
energy derivation by oxidation of organic compounds GO:0015980 5 0.057
Rat
multicellular organism growth GO:0035264 4 0.056
oxidative phosphorylation GO:0006119 1 0.055
cellular ketone metabolic process GO:0042180 11 0.053
cellular nitrogen compound metabolic process GO:0034641 290 0.053
Rat
nucleoside monophosphate catabolic process GO:0009125 4 0.051
negative regulation of biological process GO:0048519 304 0.050
Worm
response to stress GO:0006950 263 0.049
regulation of cell communication GO:0010646 232 0.047
heterocycle metabolic process GO:0046483 290 0.047
Rat
monovalent inorganic cation transport GO:0015672 42 0.046
purine nucleoside monophosphate catabolic process GO:0009128 4 0.046
hydrogen peroxide metabolic process GO:0042743 2 0.045
embryo development ending in birth or egg hatching GO:0009792 271 0.045
Worm
aromatic compound biosynthetic process GO:0019438 217 0.045
muscle structure development GO:0061061 196 0.044
small molecule catabolic process GO:0044282 3 0.044
gastrulation GO:0007369 208 0.042
atp synthesis coupled electron transport GO:0042773 1 0.041
organic acid catabolic process GO:0016054 3 0.041
single organism localization GO:1902578 225 0.041
regulation of cell differentiation GO:0045595 142 0.040
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.040
regulation of cellular ketone metabolic process GO:0010565 7 0.040
lipid storage GO:0019915 1 0.039
regulation of signal transduction GO:0009966 225 0.039
purine nucleotide metabolic process GO:0006163 27 0.039
spermatid differentiation GO:0048515 2 0.039
response to unfolded protein GO:0006986 2 0.038
cellular component morphogenesis GO:0032989 336 0.038
intracellular estrogen receptor signaling pathway GO:0030520 3 0.038
tube morphogenesis GO:0035239 349 0.038
generation of neurons GO:0048699 385 0.037
maintenance of location GO:0051235 4 0.037
nuclear transport GO:0051169 4 0.036
cellular biosynthetic process GO:0044249 286 0.036
nucleotide metabolic process GO:0009117 28 0.036
Rat
atp catabolic process GO:0006200 4 0.034
digestive system development GO:0055123 289 0.034
phosphate containing compound metabolic process GO:0006796 108 0.033
Rat
generation of precursor metabolites and energy GO:0006091 5 0.033
Rat
system process GO:0003008 185 0.033
amine metabolic process GO:0009308 2 0.033
regulation of rna metabolic process GO:0051252 224 0.033
carbohydrate derivative metabolic process GO:1901135 61 0.033
neuron development GO:0048666 262 0.032
regulation of response to stimulus GO:0048583 269 0.032
digestive tract morphogenesis GO:0048546 231 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
Rat
response to external stimulus GO:0009605 264 0.030
cell projection organization GO:0030030 284 0.030
response to hydrogen peroxide GO:0042542 3 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.029
cellular component assembly GO:0022607 170 0.028
organelle organization GO:0006996 227 0.028
spermatid development GO:0007286 2 0.027
negative regulation of signal transduction GO:0009968 94 0.027
regulation of multicellular organism growth GO:0040014 4 0.026
immune system development GO:0002520 191 0.026
heart development GO:0007507 313 0.025
regulation of anatomical structure morphogenesis GO:0022603 130 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
nucleobase containing small molecule metabolic process GO:0055086 32 0.025
Rat
protein import into nucleus GO:0006606 3 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
phagocytosis GO:0006909 3 0.024
immune system process GO:0002376 241 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
Rat
cofactor metabolic process GO:0051186 15 0.024
Rat
single organism transport GO:0044765 206 0.024
regulation of signaling GO:0023051 235 0.024
leukocyte proliferation GO:0070661 1 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
single organism organelle organization GO:1902589 199 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
regulation of multicellular organismal process GO:0051239 277 0.023
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.023
multi organism process GO:0051704 134 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.023
determination of bilateral symmetry GO:0009855 204 0.022
cellular amine metabolic process GO:0044106 2 0.022
mononuclear cell proliferation GO:0032943 1 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
regulation of sodium ion transport GO:0002028 2 0.022
response to abiotic stimulus GO:0009628 122 0.021
nucleic acid templated transcription GO:0097659 181 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.020
regulation of receptor activity GO:0010469 2 0.020
negative regulation of cell communication GO:0010648 96 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
embryonic organ development GO:0048568 381 0.020
protein metabolic process GO:0019538 183 0.019
cell morphogenesis GO:0000902 289 0.019
determination of left right symmetry GO:0007368 179 0.019
coenzyme biosynthetic process GO:0009108 2 0.019
specification of symmetry GO:0009799 204 0.019
oxidoreduction coenzyme metabolic process GO:0006733 1 0.019
Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
camera type eye development GO:0043010 222 0.019
phosphorylation GO:0016310 69 0.019
developmental growth GO:0048589 166 0.019
cellular response to reactive oxygen species GO:0034614 2 0.018
purine ribonucleotide metabolic process GO:0009150 27 0.018
nuclear export GO:0051168 1 0.018
positive regulation of transport GO:0051050 2 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
phagocytosis engulfment GO:0006911 1 0.018
nuclear import GO:0051170 3 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
lipid homeostasis GO:0055088 3 0.018
stem cell proliferation GO:0072089 4 0.018
peptide transport GO:0015833 1 0.018
brain development GO:0007420 293 0.018
neuroblast proliferation GO:0007405 2 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
cilium morphogenesis GO:0060271 85 0.017
electron transport chain GO:0022900 2 0.017
regulation of cell activation GO:0050865 1 0.017
central nervous system development GO:0007417 387 0.017
sexual reproduction GO:0019953 36 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.016
ribonucleotide metabolic process GO:0009259 27 0.016
cellular component movement GO:0006928 335 0.016
protein homooligomerization GO:0051260 3 0.016
lymphocyte proliferation GO:0046651 1 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.015
cation transport GO:0006812 81 0.015
regulation of metabolic process GO:0019222 359 0.015
Worm
regulation of blood pressure GO:0008217 1 0.015
transcription dna templated GO:0006351 181 0.015
biosynthetic process GO:0009058 294 0.015
oogenesis GO:0048477 14 0.015
adult behavior GO:0030534 2 0.015
negative regulation of signaling GO:0023057 96 0.015
membrane invagination GO:0010324 1 0.015
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.014
regulation of cell shape GO:0008360 1 0.014
cellular localization GO:0051641 97 0.014
female gamete generation GO:0007292 14 0.014
negative regulation of leukocyte differentiation GO:1902106 1 0.014
transmembrane transport GO:0055085 120 0.014
fatty acid beta oxidation GO:0006635 1 0.014
carboxylic acid catabolic process GO:0046395 3 0.014
regulation of blood vessel size GO:0050880 2 0.014
purine containing compound metabolic process GO:0072521 29 0.014
hemopoiesis GO:0030097 183 0.014
behavior GO:0007610 74 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
gland development GO:0048732 143 0.013
phosphorus metabolic process GO:0006793 109 0.013
Rat
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
mitochondrion morphogenesis GO:0070584 2 0.013
response to organic substance GO:0010033 153 0.013
regulation of biological quality GO:0065008 263 0.013
regulation of myotube differentiation GO:0010830 2 0.013
deoxyribonucleotide biosynthetic process GO:0009263 1 0.013
lipid catabolic process GO:0016042 4 0.013
nucleoside biosynthetic process GO:0009163 2 0.013
nucleic acid metabolic process GO:0090304 244 0.013
regulation of muscle contraction GO:0006937 3 0.013
central nervous system neuron differentiation GO:0021953 74 0.013
cytoskeleton organization GO:0007010 96 0.012
establishment of localization GO:0051234 244 0.012
Worm
positive regulation of biological process GO:0048518 253 0.012
negative regulation of developmental process GO:0051093 65 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
sensory organ development GO:0007423 393 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
b cell activation GO:0042113 2 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
positive regulation of striated muscle cell differentiation GO:0051155 1 0.012
glycosyl compound metabolic process GO:1901657 11 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
Rat
transport GO:0006810 220 0.011
Worm
regulation of primary metabolic process GO:0080090 311 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
regulation of cell projection organization GO:0031344 44 0.011
mitochondrial transport GO:0006839 2 0.011
protein import GO:0017038 3 0.011
chemosensory behavior GO:0007635 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
cellular component biogenesis GO:0044085 178 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
cell proliferation GO:0008283 80 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.011
actin cytoskeleton organization GO:0030036 63 0.011
ribonucleoside monophosphate metabolic process GO:0009161 5 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
meiotic nuclear division GO:0007126 4 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
hormone secretion GO:0046879 2 0.010
eye development GO:0001654 277 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
regulation of cellular metabolic process GO:0031323 320 0.010

idh3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.035
disease of metabolism DOID:0014667 0 0.030
amino acid metabolic disorder DOID:9252 0 0.021
inherited metabolic disorder DOID:655 0 0.021
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.017
mitochondrial metabolism disease DOID:700 0 0.016
musculoskeletal system disease DOID:17 0 0.014