Danio rerio

0 known processes

ercc3

excision repair cross-complementing rodent repair deficiency, complementation group 3

(Aliases: wu:fc25f08)

ercc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.234
lipid storage GO:0019915 1 0.070
modification dependent protein catabolic process GO:0019941 3 0.066
maintenance of location GO:0051235 4 0.062
cellular protein catabolic process GO:0044257 4 0.055
nitrogen compound metabolic process GO:0006807 319 0.054
Human Yeast Rat Fly
aging GO:0007568 2 0.053
meiotic nuclear division GO:0007126 4 0.051
ubiquitin dependent protein catabolic process GO:0006511 3 0.050
proteasomal protein catabolic process GO:0010498 2 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.046
organic cyclic compound metabolic process GO:1901360 301 0.044
Human Yeast Rat Fly
heterocycle metabolic process GO:0046483 290 0.044
Human Yeast Rat Fly
cytokinesis GO:0000910 3 0.042
modification dependent macromolecule catabolic process GO:0043632 3 0.041
single organism metabolic process GO:0044710 217 0.041
Human Yeast Rat
multicellular organism growth GO:0035264 4 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.037
Human Yeast Rat Fly
positive regulation of transport GO:0051050 2 0.036
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.036
positive regulation of cell cycle GO:0045787 3 0.035
regulation of macromolecule metabolic process GO:0060255 317 0.034
Human Yeast Fly
response to chemical GO:0042221 320 0.033
cellular amine metabolic process GO:0044106 2 0.033
negative regulation of kinase activity GO:0033673 4 0.033
regulation of cellular metabolic process GO:0031323 320 0.033
Human Yeast Fly
meiotic cell cycle process GO:1903046 3 0.033
negative regulation of protein phosphorylation GO:0001933 4 0.033
stem cell proliferation GO:0072089 4 0.032
regulation of meiotic cell cycle GO:0051445 1 0.031
cellular ketone metabolic process GO:0042180 11 0.031
ribonucleoside monophosphate catabolic process GO:0009158 4 0.030
Human Yeast Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.030
nucleic acid templated transcription GO:0097659 181 0.029
Human Yeast Fly
regulation of biological quality GO:0065008 263 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
Human Yeast Fly
regionalization GO:0003002 274 0.029
stem cell division GO:0017145 1 0.029
cellular protein metabolic process GO:0044267 129 0.029
Human Yeast Rat
regulation of cellular amine metabolic process GO:0033238 0 0.028
rna metabolic process GO:0016070 219 0.028
Human Yeast Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
Human Yeast Fly
nucleic acid metabolic process GO:0090304 244 0.028
Human Yeast Rat Fly
regulation of multicellular organism growth GO:0040014 4 0.028
aromatic compound biosynthetic process GO:0019438 217 0.028
Human Yeast Fly
macromolecule biosynthetic process GO:0009059 227 0.027
Human Yeast Fly
transcription dna templated GO:0006351 181 0.027
Human Yeast Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
negative regulation of biological process GO:0048519 304 0.027
protein metabolic process GO:0019538 183 0.027
Human Yeast Rat
nuclear transport GO:0051169 4 0.027
Yeast
regulation of protein ubiquitination GO:0031396 3 0.026
organic substance biosynthetic process GO:1901576 289 0.026
Human Yeast Fly
nucleocytoplasmic transport GO:0006913 4 0.026
Yeast
amine metabolic process GO:0009308 2 0.026
transport GO:0006810 220 0.026
Yeast
cellular macromolecule metabolic process GO:0044260 391 0.026
Human Yeast Rat Fly
establishment of protein localization to organelle GO:0072594 4 0.026
positive regulation of biological process GO:0048518 253 0.026
Human
compound eye development GO:0048749 2 0.025
establishment of localization GO:0051234 244 0.025
Yeast
single fertilization GO:0007338 3 0.025
regulation of protein transport GO:0051223 3 0.025
locomotion GO:0040011 313 0.024
positive regulation of catabolic process GO:0009896 4 0.024
gene expression GO:0010467 252 0.024
Human Yeast Fly
positive regulation of cellular catabolic process GO:0031331 3 0.024
phagocytosis GO:0006909 3 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.023
Human Yeast Rat Fly
protein localization to nucleus GO:0034504 3 0.023
biosynthetic process GO:0009058 294 0.023
Human Yeast Fly
cellular amino acid metabolic process GO:0006520 7 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
mitotic dna integrity checkpoint GO:0044774 4 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
Human Yeast Fly
cellular component biogenesis GO:0044085 178 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
response to stress GO:0006950 263 0.023
Human Yeast Rat
rna localization GO:0006403 4 0.023
Yeast
atp catabolic process GO:0006200 4 0.023
Human Yeast Rat
organonitrogen compound metabolic process GO:1901564 74 0.022
Human Yeast Rat
small molecule metabolic process GO:0044281 77 0.022
Human Yeast Rat
morphogenesis of an epithelium GO:0002009 333 0.022
regulation of transcription dna templated GO:0006355 213 0.022
Human Yeast
positive regulation of cellular component biogenesis GO:0044089 3 0.022
endosomal transport GO:0016197 2 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
Worm
regulation of establishment of protein localization GO:0070201 4 0.022
digestive system development GO:0055123 289 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
Human Yeast
oxoacid metabolic process GO:0043436 31 0.022
multi organism process GO:0051704 134 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
Human Yeast Rat
regulation of protein catabolic process GO:0042176 1 0.021
cellular component morphogenesis GO:0032989 336 0.021
meiosis i GO:0007127 1 0.021
nucleoside monophosphate catabolic process GO:0009125 4 0.021
Human Yeast Rat
rna biosynthetic process GO:0032774 181 0.021
Human Yeast Fly
response to external stimulus GO:0009605 264 0.021
cell morphogenesis GO:0000902 289 0.021
mitotic cell cycle GO:0000278 64 0.021
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.021
Human Yeast Fly
nuclear import GO:0051170 3 0.021
neuroblast proliferation GO:0007405 2 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
Human Yeast Fly
regulation of rna biosynthetic process GO:2001141 213 0.020
Human Yeast
protein heterooligomerization GO:0051291 1 0.020
regulation of binding GO:0051098 3 0.020
chromosome organization involved in meiosis GO:0070192 1 0.020
single organism nuclear import GO:1902593 3 0.019
signal transduction GO:0007165 455 0.019
chordate embryonic development GO:0043009 271 0.019
regulation of metabolic process GO:0019222 359 0.019
Human Yeast Fly
cellular component disassembly GO:0022411 1 0.019
protein polymerization GO:0051258 4 0.019
vasculature development GO:0001944 278 0.019
organic acid metabolic process GO:0006082 31 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
cell projection morphogenesis GO:0048858 244 0.018
homeostatic process GO:0042592 142 0.018
response to drug GO:0042493 3 0.018
macromolecule modification GO:0043412 111 0.018
Human Yeast Rat
carboxylic acid metabolic process GO:0019752 22 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
Human Yeast Rat Fly
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
protein import GO:0017038 3 0.018
lateral inhibition GO:0046331 1 0.018
spermatid differentiation GO:0048515 2 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
Human Yeast
regulation of cell shape GO:0008360 1 0.018
immune system process GO:0002376 241 0.018
single organism membrane fusion GO:0044801 2 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
meiotic chromosome segregation GO:0045132 3 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.018
Human Yeast Fly
gtp catabolic process GO:0006184 2 0.018
membrane fusion GO:0061025 2 0.018
stem cell maintenance GO:0019827 4 0.018
protein import into nucleus GO:0006606 3 0.018
cognition GO:0050890 1 0.018
protein modification process GO:0036211 100 0.018
Human Yeast Rat
rna processing GO:0006396 25 0.017
Fly
female gonad development GO:0008585 4 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
Human Yeast Fly
cellular component assembly GO:0022607 170 0.017
regulation of cell communication GO:0010646 232 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
regulation of cell activation GO:0050865 1 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
response to topologically incorrect protein GO:0035966 2 0.017
gtp metabolic process GO:0046039 4 0.017
cellular component movement GO:0006928 335 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of primary metabolic process GO:0080090 311 0.017
Human Yeast Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
gastrulation GO:0007369 208 0.017
regulation of rna metabolic process GO:0051252 224 0.017
Human Yeast Fly
eye development GO:0001654 277 0.017
single organism organelle organization GO:1902589 199 0.017
fertilization GO:0009566 3 0.017
regulation of reproductive process GO:2000241 4 0.017
golgi vesicle transport GO:0048193 3 0.017
regulation of signal transduction GO:0009966 225 0.017
brain development GO:0007420 293 0.016
death GO:0016265 121 0.016
Human
central nervous system development GO:0007417 387 0.016
regulation of cytokine production GO:0001817 3 0.016
mrna processing GO:0006397 14 0.016
Fly
tube morphogenesis GO:0035239 349 0.016
regulation of response to cytokine stimulus GO:0060759 3 0.016
primary neural tube formation GO:0014020 1 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
antimicrobial humoral response GO:0019730 2 0.016
b cell activation GO:0042113 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
negative regulation of cellular process GO:0048523 283 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
Human Yeast
generation of neurons GO:0048699 385 0.016
Human
spermatid development GO:0007286 2 0.016
protein localization to plasma membrane GO:0072659 1 0.016
anterior posterior pattern specification GO:0009952 152 0.016
neuron differentiation GO:0030182 353 0.015
Human
double strand break repair GO:0006302 3 0.015
single organism transport GO:0044765 206 0.015
Yeast
mitochondrion organization GO:0007005 4 0.015
nucleic acid transport GO:0050657 2 0.015
Yeast
female sex differentiation GO:0046660 4 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of developmental process GO:0050793 247 0.015
rna splicing GO:0008380 16 0.015
Fly
positive regulation of map kinase activity GO:0043406 3 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
digestive tract development GO:0048565 265 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
somatic muscle development GO:0007525 4 0.015
regulation of receptor activity GO:0010469 2 0.015
locomotor rhythm GO:0045475 3 0.015
positive regulation of cellular process GO:0048522 201 0.015
Human
cell part morphogenesis GO:0032990 246 0.015
ameboidal type cell migration GO:0001667 143 0.015
response to organic substance GO:0010033 153 0.015
peptide transport GO:0015833 1 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.015
heart development GO:0007507 313 0.015
mitotic dna damage checkpoint GO:0044773 4 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
protein stabilization GO:0050821 2 0.015
cellular transition metal ion homeostasis GO:0046916 3 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
sensory organ development GO:0007423 393 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
protein dephosphorylation GO:0006470 3 0.014
positive regulation of cell activation GO:0050867 1 0.014
cellular protein modification process GO:0006464 100 0.014
Human Yeast Rat
regulation of signaling GO:0023051 235 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
dna templated transcription elongation GO:0006354 3 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
negative regulation of metabolic process GO:0009892 86 0.014
mononuclear cell proliferation GO:0032943 1 0.014
positive regulation of secretion GO:0051047 1 0.014
leukocyte proliferation GO:0070661 1 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
adherens junction organization GO:0034332 4 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
hormone transport GO:0009914 2 0.014
regulation of blood pressure GO:0008217 1 0.014
developmental growth GO:0048589 166 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
Human Yeast Rat
protein acetylation GO:0006473 2 0.013
blood vessel morphogenesis GO:0048514 216 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
cellular respiration GO:0045333 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
Human Yeast Fly
positive regulation of chromosome organization GO:2001252 1 0.013
cellular response to external stimulus GO:0071496 2 0.013
chemosensory behavior GO:0007635 1 0.013
phagocytosis engulfment GO:0006911 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
Human Yeast
g2 dna damage checkpoint GO:0031572 3 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
protein polyubiquitination GO:0000209 4 0.013
regulation of gene expression GO:0010468 265 0.013
Human Yeast Fly
skeletal system development GO:0001501 181 0.013
negative regulation of cytokine production GO:0001818 1 0.013
response to carbohydrate GO:0009743 3 0.013
lymphocyte proliferation GO:0046651 1 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
Fly
regulation of synapse organization GO:0050807 3 0.013
response to monosaccharide GO:0034284 3 0.013
cellular response to starvation GO:0009267 1 0.013
spindle assembly GO:0051225 2 0.013
regulation of chromosome segregation GO:0051983 1 0.013
regulation of hormone secretion GO:0046883 2 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
nucleobase containing compound transport GO:0015931 2 0.013
Yeast
tissue remodeling GO:0048771 4 0.013
regulation of circadian rhythm GO:0042752 4 0.013
cellular response to radiation GO:0071478 4 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
tube closure GO:0060606 1 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
protein complex disassembly GO:0043241 1 0.012
single organism localization GO:1902578 225 0.012
Yeast
cellular localization GO:0051641 97 0.012
Yeast
liver development GO:0001889 96 0.012
rna 3 end processing GO:0031123 2 0.012
membrane invagination GO:0010324 1 0.012
response to biotic stimulus GO:0009607 97 0.012
mrna metabolic process GO:0016071 20 0.012
Fly
regulation of nucleoside metabolic process GO:0009118 2 0.012
carbohydrate homeostasis GO:0033500 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
response to abiotic stimulus GO:0009628 122 0.012
Human Rat Fly
cellular response to extracellular stimulus GO:0031668 2 0.012
protein secretion GO:0009306 1 0.012
cell cycle process GO:0022402 53 0.012
Human
recombinational repair GO:0000725 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
hormone secretion GO:0046879 2 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
positive regulation of translation GO:0045727 1 0.012
double strand break repair via homologous recombination GO:0000724 1 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
sister chromatid cohesion GO:0007062 2 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
Yeast
regulation of multicellular organismal process GO:0051239 277 0.012
response to nutrient GO:0007584 3 0.012
regulation of protein targeting GO:1903533 2 0.012
adult behavior GO:0030534 2 0.012
cell cycle GO:0007049 93 0.012
Human
positive regulation of protein kinase b signaling GO:0051897 1 0.012
regulation of protein complex assembly GO:0043254 3 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
regulation of protein metabolic process GO:0051246 56 0.012
pathway restricted smad protein phosphorylation GO:0060389 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
hepaticobiliary system development GO:0061008 98 0.012
actin filament polymerization GO:0030041 2 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.011
gland development GO:0048732 143 0.011
negative regulation of immune response GO:0050777 2 0.011
protein homooligomerization GO:0051260 3 0.011
cell cycle arrest GO:0007050 1 0.011
response to other organism GO:0051707 97 0.011
response to glucose GO:0009749 3 0.011
secondary metabolic process GO:0019748 3 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
cell matrix adhesion GO:0007160 4 0.011
macromolecular complex disassembly GO:0032984 1 0.011
activation of mapk activity GO:0000187 3 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
nuclear export GO:0051168 1 0.011
Yeast
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
transcription from rna polymerase iii promoter GO:0006383 1 0.011
response to hexose GO:0009746 3 0.011
system process GO:0003008 185 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
autophagy GO:0006914 4 0.011
somatic stem cell maintenance GO:0035019 1 0.011
protein acylation GO:0043543 3 0.011
lamellipodium assembly GO:0030032 1 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
phosphorylation GO:0016310 69 0.011
Human Yeast Rat
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of filopodium assembly GO:0051489 2 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
centrosome organization GO:0051297 1 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
negative regulation of signaling GO:0023057 96 0.011
localization of cell GO:0051674 244 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
response to ketone GO:1901654 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
b cell differentiation GO:0030183 1 0.011
regulation of translational initiation GO:0006446 1 0.011
response to corticosteroid GO:0031960 1 0.011
regulation of organelle assembly GO:1902115 4 0.011
endocrine process GO:0050886 2 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
regulation of response to stimulus GO:0048583 269 0.011
head development GO:0060322 303 0.010
somite development GO:0061053 96 0.010
negative regulation of myeloid cell differentiation GO:0045638 1 0.010
digestive tract morphogenesis GO:0048546 231 0.010
glucose homeostasis GO:0042593 1 0.010
phosphorus metabolic process GO:0006793 109 0.010
Human Yeast Rat
positive regulation of striated muscle tissue development GO:0045844 1 0.010
regulation of cellular component organization GO:0051128 86 0.010
cellular response to nutrient levels GO:0031669 2 0.010
cell aging GO:0007569 2 0.010
cellular biosynthetic process GO:0044249 286 0.010
Human Yeast Fly
embryonic organ morphogenesis GO:0048562 274 0.010
cell substrate junction assembly GO:0007044 2 0.010
organelle organization GO:0006996 227 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
regulation of biosynthetic process GO:0009889 250 0.010
Human Yeast
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
negative regulation of nuclear division GO:0051784 3 0.010
mrna 3 end processing GO:0031124 2 0.010
regulation of protein binding GO:0043393 3 0.010
cell fate commitment GO:0045165 99 0.010
forebrain regionalization GO:0021871 4 0.010
regulation of cellular protein metabolic process GO:0032268 52 0.010
intracellular mrna localization GO:0008298 1 0.010

ercc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
inherited metabolic disorder DOID:655 0 0.011