Danio rerio

30 known processes

med29

mediator complex subunit 29

(Aliases: ixl,zgc:109789,MGC109789,dkfzp434h247,DKFZp434H247,chunp6869)

med29 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.624
cellular component movement GO:0006928 335 0.289
embryo development ending in birth or egg hatching GO:0009792 271 0.169
locomotion GO:0040011 313 0.147
cell motility GO:0048870 244 0.121
cell migration GO:0016477 237 0.115
localization of cell GO:0051674 244 0.112
establishment of protein localization to organelle GO:0072594 4 0.088
regulation of macromolecule metabolic process GO:0060255 317 0.086
Fly
signal transduction GO:0007165 455 0.077
cell part morphogenesis GO:0032990 246 0.077
establishment of localization GO:0051234 244 0.074
heart development GO:0007507 313 0.071
cellular component morphogenesis GO:0032989 336 0.067
cell surface receptor signaling pathway GO:0007166 325 0.066
transport GO:0006810 220 0.063
response to stress GO:0006950 263 0.062
alpha amino acid metabolic process GO:1901605 3 0.058
negative regulation of biological process GO:0048519 304 0.058
response to chemical GO:0042221 320 0.057
heterocycle metabolic process GO:0046483 290 0.057
Fly
regulation of meiotic cell cycle GO:0051445 1 0.055
cell projection organization GO:0030030 284 0.055
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
nitrogen compound metabolic process GO:0006807 319 0.053
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.053
Fly
cell projection morphogenesis GO:0048858 244 0.050
cell morphogenesis GO:0000902 289 0.049
stem cell proliferation GO:0072089 4 0.048
organelle organization GO:0006996 227 0.047
meiotic cell cycle process GO:1903046 3 0.047
regulation of signal transduction GO:0009966 225 0.046
sensory organ development GO:0007423 393 0.045
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.045
regulation of reproductive process GO:2000241 4 0.043
regulation of biological quality GO:0065008 263 0.041
cellular response to external stimulus GO:0071496 2 0.041
regulation of mrna splicing via spliceosome GO:0048024 3 0.041
organelle assembly GO:0070925 110 0.041
nuclear division GO:0000280 23 0.039
eye development GO:0001654 277 0.039
biosynthetic process GO:0009058 294 0.039
Fly
protein import into nucleus GO:0006606 3 0.039
cellular carbohydrate metabolic process GO:0044262 4 0.039
maintenance of location GO:0051235 4 0.039
single organism nuclear import GO:1902593 3 0.038
neuron projection development GO:0031175 180 0.038
meiotic chromosome segregation GO:0045132 3 0.037
cellular component assembly GO:0022607 170 0.037
secondary metabolic process GO:0019748 3 0.037
oxoacid metabolic process GO:0043436 31 0.036
morphogenesis of an epithelium GO:0002009 333 0.036
negative regulation of cellular process GO:0048523 283 0.035
regulation of rna metabolic process GO:0051252 224 0.035
Fly
single organism organelle organization GO:1902589 199 0.035
aging GO:0007568 2 0.034
meiotic nuclear division GO:0007126 4 0.034
extrinsic apoptotic signaling pathway GO:0097191 3 0.033
regulation of translational initiation GO:0006446 1 0.033
lipid storage GO:0019915 1 0.033
neuron projection morphogenesis GO:0048812 161 0.033
nuclear transport GO:0051169 4 0.033
generation of neurons GO:0048699 385 0.033
protein localization to nucleus GO:0034504 3 0.032
regulation of metabolic process GO:0019222 359 0.032
Fly
neuron development GO:0048666 262 0.032
gene expression GO:0010467 252 0.030
Fly
establishment of synaptic vesicle localization GO:0097480 1 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
Fly
embryonic organ development GO:0048568 381 0.029
neuron differentiation GO:0030182 353 0.029
regulation of cell communication GO:0010646 232 0.029
cellular amino acid metabolic process GO:0006520 7 0.029
microtubule based process GO:0007017 60 0.029
regulation of signaling GO:0023051 235 0.028
phagocytosis GO:0006909 3 0.028
camera type eye development GO:0043010 222 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
cellular response to starvation GO:0009267 1 0.028
i kappab kinase nf kappab signaling GO:0007249 4 0.026
response to abiotic stimulus GO:0009628 122 0.026
heart morphogenesis GO:0003007 156 0.026
compound eye development GO:0048749 2 0.026
mitotic dna integrity checkpoint GO:0044774 4 0.026
cellular biosynthetic process GO:0044249 286 0.026
Fly
neuroblast proliferation GO:0007405 2 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
single organism membrane fusion GO:0044801 2 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
Fly
organic substance biosynthetic process GO:1901576 289 0.024
Fly
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.024
fertilization GO:0009566 3 0.024
positive regulation of cell cycle GO:0045787 3 0.024
nucleoside monophosphate catabolic process GO:0009125 4 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
translational initiation GO:0006413 3 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
response to external stimulus GO:0009605 264 0.023
retina development in camera type eye GO:0060041 146 0.023
actin filament polymerization GO:0030041 2 0.023
sleep GO:0030431 1 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
Fly
dorsal ventral pattern formation GO:0009953 125 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
spliceosomal snrnp assembly GO:0000387 2 0.022
muscle structure development GO:0061061 196 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
organic acid metabolic process GO:0006082 31 0.022
regionalization GO:0003002 274 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
nuclear import GO:0051170 3 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.021
Fly
protein import GO:0017038 3 0.021
chemotaxis GO:0006935 104 0.021
regulation of mrna processing GO:0050684 3 0.021
cytoskeleton organization GO:0007010 96 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
positive regulation of transport GO:0051050 2 0.021
endocytosis GO:0006897 16 0.021
epithelial cell morphogenesis GO:0003382 2 0.020
vesicle mediated transport GO:0016192 22 0.020
chemosensory behavior GO:0007635 1 0.020
cellular response to nutrient levels GO:0031669 2 0.020
anterior posterior pattern specification GO:0009952 152 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.020
spindle assembly GO:0051225 2 0.020
regulation of binding GO:0051098 3 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
Fly
vasculature development GO:0001944 278 0.019
cellular protein catabolic process GO:0044257 4 0.019
reproduction GO:0000003 40 0.018
adult behavior GO:0030534 2 0.018
regulation of cell projection assembly GO:0060491 4 0.018
protein targeting to nucleus GO:0044744 3 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
blood vessel development GO:0001568 246 0.018
spindle assembly involved in mitosis GO:0090307 1 0.018
ameboidal type cell migration GO:0001667 143 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
Fly
digestive tract development GO:0048565 265 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
small molecule metabolic process GO:0044281 77 0.017
stem cell division GO:0017145 1 0.017
mitotic g2 m transition checkpoint GO:0044818 3 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
single fertilization GO:0007338 3 0.017
phagocytosis engulfment GO:0006911 1 0.017
regulation of response to stimulus GO:0048583 269 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
Fly
multi organism cellular process GO:0044764 2 0.017
cellular amine metabolic process GO:0044106 2 0.017
organelle fission GO:0048285 23 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
regulation of cell shape GO:0008360 1 0.017
negative regulation of cell communication GO:0010648 96 0.017
internal protein amino acid acetylation GO:0006475 2 0.016
mitotic dna damage checkpoint GO:0044773 4 0.016
regulation of cytokine production GO:0001817 3 0.016
multicellular organism growth GO:0035264 4 0.016
synaptic vesicle transport GO:0048489 1 0.016
positive regulation of catabolic process GO:0009896 4 0.016
blood vessel morphogenesis GO:0048514 216 0.016
cell proliferation GO:0008283 80 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
stem cell maintenance GO:0019827 4 0.016
angiogenesis GO:0001525 158 0.016
axonogenesis GO:0007409 152 0.016
digestive system development GO:0055123 289 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
Fly
gland development GO:0048732 143 0.016
regulation of receptor activity GO:0010469 2 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
viral process GO:0016032 1 0.015
amine metabolic process GO:0009308 2 0.015
adherens junction organization GO:0034332 4 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
protein complex disassembly GO:0043241 1 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
cell death GO:0008219 121 0.015
immune system process GO:0002376 241 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
single organism transport GO:0044765 206 0.015
axon guidance GO:0007411 86 0.015
protein acylation GO:0043543 3 0.015
cognition GO:0050890 1 0.015
negative regulation of signaling GO:0023057 96 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
response to drug GO:0042493 3 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
regulation of organ growth GO:0046620 3 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
double strand break repair via homologous recombination GO:0000724 1 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
atp catabolic process GO:0006200 4 0.014
regulation of endothelial cell proliferation GO:0001936 1 0.014
nucleic acid templated transcription GO:0097659 181 0.014
Fly
synaptic vesicle localization GO:0097479 1 0.014
neurotransmitter transport GO:0006836 2 0.014
homeostatic process GO:0042592 142 0.014
positive regulation of epithelial cell proliferation GO:0050679 1 0.014
transcription dna templated GO:0006351 181 0.014
Fly
regulation of programmed cell death GO:0043067 101 0.014
regulation of dna recombination GO:0000018 2 0.014
somite development GO:0061053 96 0.014
determination of bilateral symmetry GO:0009855 204 0.014
mitotic g2 dna damage checkpoint GO:0007095 3 0.014
pole plasm assembly GO:0007315 4 0.014
interspecies interaction between organisms GO:0044419 4 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of gene expression GO:0010468 265 0.014
Fly
regulation of oocyte development GO:0060281 3 0.014
brain development GO:0007420 293 0.014
cell projection assembly GO:0030031 64 0.014
mitochondrion organization GO:0007005 4 0.014
protein metabolic process GO:0019538 183 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
protein complex localization GO:0031503 1 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
regulation of protein localization to nucleus GO:1900180 2 0.013
regulation of wound healing GO:0061041 2 0.013
cellular pigmentation GO:0033059 30 0.013
protein heterooligomerization GO:0051291 1 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
head development GO:0060322 303 0.013
pronuclear migration GO:0035046 1 0.013
cellular component biogenesis GO:0044085 178 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
regulation of protein transport GO:0051223 3 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
cellular response to growth factor stimulus GO:0071363 39 0.013
regulation of cellular component organization GO:0051128 86 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
negative regulation of reproductive process GO:2000242 3 0.013
negative regulation of leukocyte differentiation GO:1902106 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
positive regulation of endothelial cell proliferation GO:0001938 1 0.013
post embryonic organ development GO:0048569 4 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
negative regulation of signal transduction GO:0009968 94 0.013
muscle cell differentiation GO:0042692 139 0.013
positive regulation of cellular process GO:0048522 201 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
Fly
single organism metabolic process GO:0044710 217 0.013
striated muscle tissue development GO:0014706 110 0.013
cytoplasm organization GO:0007028 4 0.013
nucleic acid metabolic process GO:0090304 244 0.012
Fly
membrane fusion GO:0061025 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
central nervous system development GO:0007417 387 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
rna metabolic process GO:0016070 219 0.012
Fly
muscle organ development GO:0007517 101 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
negative regulation of gene expression GO:0010629 65 0.012
regulation of cell development GO:0060284 100 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
tissue remodeling GO:0048771 4 0.012
determination of left right symmetry GO:0007368 179 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
specification of symmetry GO:0009799 204 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
microtubule organizing center organization GO:0031023 1 0.012
spermatid development GO:0007286 2 0.012
female meiotic division GO:0007143 2 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
autophagy GO:0006914 4 0.012
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
protein acetylation GO:0006473 2 0.012
gtp catabolic process GO:0006184 2 0.012
glial cell migration GO:0008347 3 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
cellular response to organic substance GO:0071310 105 0.011
leukocyte proliferation GO:0070661 1 0.011
pigmentation GO:0043473 85 0.011
tube morphogenesis GO:0035239 349 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
Fly
centrosome duplication GO:0051298 1 0.011
protein dephosphorylation GO:0006470 3 0.011
regulation of transporter activity GO:0032409 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
cell matrix adhesion GO:0007160 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
centrosome cycle GO:0007098 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of primary metabolic process GO:0080090 311 0.011
Fly
neuromuscular synaptic transmission GO:0007274 2 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
developmental growth GO:0048589 166 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
Fly
cell aging GO:0007569 2 0.011
negative regulation of cytokine production GO:0001818 1 0.011
growth GO:0040007 174 0.011
membrane invagination GO:0010324 1 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
macromolecular complex disassembly GO:0032984 1 0.011
negative regulation of nuclear division GO:0051784 3 0.011
cilium morphogenesis GO:0060271 85 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
cellular component disassembly GO:0022411 1 0.011
protein polymerization GO:0051258 4 0.011
locomotor rhythm GO:0045475 3 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
cellular response to stress GO:0033554 62 0.011
cellular ketone metabolic process GO:0042180 11 0.011
centrosome organization GO:0051297 1 0.011
organelle fusion GO:0048284 3 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
single organism localization GO:1902578 225 0.010
intracellular signal transduction GO:0035556 85 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
neuron projection guidance GO:0097485 86 0.010
lymphocyte proliferation GO:0046651 1 0.010
regulation of localization GO:0032879 104 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
peptidyl serine modification GO:0018209 2 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010

med29 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.019
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.010