Danio rerio

0 known processes

med21

mediator complex subunit 21

(Aliases: wu:fk48d02,surb7,zgc:56532,fk48d02)

med21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.226
aromatic compound biosynthetic process GO:0019438 217 0.118
Human
cellular biosynthetic process GO:0044249 286 0.109
Human
macromolecule biosynthetic process GO:0009059 227 0.091
Human
biosynthetic process GO:0009058 294 0.091
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.086
Human
organic cyclic compound metabolic process GO:1901360 301 0.076
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.074
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.071
Mouse
regulation of metabolic process GO:0019222 359 0.065
Human
regulation of rna metabolic process GO:0051252 224 0.061
Human
negative regulation of biological process GO:0048519 304 0.056
Mouse
organic substance biosynthetic process GO:1901576 289 0.056
Human
regulation of meiotic cell cycle GO:0051445 1 0.054
regulation of cellular biosynthetic process GO:0031326 245 0.052
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.051
Human
cellular macromolecule metabolic process GO:0044260 391 0.049
Human
nucleobase containing compound metabolic process GO:0006139 274 0.048
Human
rna biosynthetic process GO:0032774 181 0.048
Human
meiotic nuclear division GO:0007126 4 0.046
protein modification process GO:0036211 100 0.044
organic cyclic compound biosynthetic process GO:1901362 223 0.043
Human
nuclear transport GO:0051169 4 0.040
nitrogen compound metabolic process GO:0006807 319 0.040
Human
multi organism cellular process GO:0044764 2 0.040
nucleic acid metabolic process GO:0090304 244 0.038
Human
heterocycle metabolic process GO:0046483 290 0.038
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.038
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.037
Human
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.036
protein metabolic process GO:0019538 183 0.036
cellular protein metabolic process GO:0044267 129 0.035
central nervous system development GO:0007417 387 0.035
locomotion GO:0040011 313 0.035
Worm
negative regulation of cellular process GO:0048523 283 0.034
Mouse
aging GO:0007568 2 0.034
gene expression GO:0010467 252 0.032
Human
cell projection organization GO:0030030 284 0.032
Worm
response to stress GO:0006950 263 0.032
cellular response to external stimulus GO:0071496 2 0.031
positive regulation of transport GO:0051050 2 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
response to external stimulus GO:0009605 264 0.030
cellular component morphogenesis GO:0032989 336 0.029
establishment of localization GO:0051234 244 0.029
chromosome organization GO:0051276 31 0.029
organelle organization GO:0006996 227 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
cell projection morphogenesis GO:0048858 244 0.028
embryonic organ development GO:0048568 381 0.028
cell morphogenesis GO:0000902 289 0.028
regulation of establishment of protein localization GO:0070201 4 0.027
interspecies interaction between organisms GO:0044419 4 0.027
brain development GO:0007420 293 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.027
Human
regulation of primary metabolic process GO:0080090 311 0.026
Human
cell death GO:0008219 121 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
Human
cellular aromatic compound metabolic process GO:0006725 295 0.026
Human
cellular response to nutrient levels GO:0031669 2 0.025
chromosome organization involved in meiosis GO:0070192 1 0.025
rna metabolic process GO:0016070 219 0.025
Human
establishment of protein localization to organelle GO:0072594 4 0.025
viral process GO:0016032 1 0.025
single organism metabolic process GO:0044710 217 0.024
cell part morphogenesis GO:0032990 246 0.024
adult behavior GO:0030534 2 0.024
regulation of apoptotic process GO:0042981 98 0.024
embryonic organ morphogenesis GO:0048562 274 0.023
muscle structure development GO:0061061 196 0.023
protein complex disassembly GO:0043241 1 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.022
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
Human
regulation of binding GO:0051098 3 0.021
transcription dna templated GO:0006351 181 0.021
Human
regulation of gene expression GO:0010468 265 0.021
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.020
mitochondrion organization GO:0007005 4 0.020
response to abiotic stimulus GO:0009628 122 0.020
response to nutrient GO:0007584 3 0.020
neuron projection development GO:0031175 180 0.020
Worm
regulation of protein transport GO:0051223 3 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
stem cell proliferation GO:0072089 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
Human
cellular response to starvation GO:0009267 1 0.019
maintenance of location GO:0051235 4 0.019
cellular component biogenesis GO:0044085 178 0.019
protein acylation GO:0043543 3 0.019
cellular protein catabolic process GO:0044257 4 0.019
nuclear import GO:0051170 3 0.018
protein import into nucleus GO:0006606 3 0.018
programmed cell death GO:0012501 119 0.018
translational initiation GO:0006413 3 0.018
regulation of transcription dna templated GO:0006355 213 0.018
Human
protein localization to plasma membrane GO:0072659 1 0.018
apoptotic process GO:0006915 116 0.017
olfactory bulb development GO:0021772 4 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
response to carbohydrate GO:0009743 3 0.017
neuron development GO:0048666 262 0.017
Worm
negative regulation of protein transport GO:0051224 3 0.017
single organism nuclear import GO:1902593 3 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
cilium morphogenesis GO:0060271 85 0.017
fertilization GO:0009566 3 0.017
sensory organ development GO:0007423 393 0.016
regionalization GO:0003002 274 0.016
macromolecule modification GO:0043412 111 0.016
phagocytosis GO:0006909 3 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
organism emergence from protective structure GO:0071684 4 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
regulation of cytokine production GO:0001817 3 0.016
meiotic chromosome segregation GO:0045132 3 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
death GO:0016265 121 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
cellular component disassembly GO:0022411 1 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
response to chemical GO:0042221 320 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
response to monosaccharide GO:0034284 3 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
tube morphogenesis GO:0035239 349 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
heart morphogenesis GO:0003007 156 0.015
nucleic acid templated transcription GO:0097659 181 0.015
Human
response to hexose GO:0009746 3 0.014
neuron differentiation GO:0030182 353 0.014
Worm
transport GO:0006810 220 0.014
protein import GO:0017038 3 0.014
autophagy GO:0006914 4 0.014
signal transduction GO:0007165 455 0.014
positive regulation of cell cycle GO:0045787 3 0.014
protein acetylation GO:0006473 2 0.014
protein targeting to nucleus GO:0044744 3 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
sensory organ morphogenesis GO:0090596 200 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
multicellular organism growth GO:0035264 4 0.014
heart development GO:0007507 313 0.014
peptidyl serine modification GO:0018209 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
protein localization to nucleus GO:0034504 3 0.013
eye morphogenesis GO:0048592 144 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
Human
macromolecular complex disassembly GO:0032984 1 0.013
chromatin modification GO:0016568 21 0.013
chemosensory behavior GO:0007635 1 0.013
eye development GO:0001654 277 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
protein polyubiquitination GO:0000209 4 0.013
cellular respiration GO:0045333 3 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
locomotor rhythm GO:0045475 3 0.013
regulation of cell communication GO:0010646 232 0.013
positive regulation of catabolic process GO:0009896 4 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.012
single organism organelle organization GO:1902589 199 0.012
neuron projection guidance GO:0097485 86 0.012
oxoacid metabolic process GO:0043436 31 0.012
lateral inhibition GO:0046331 1 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
response to glucose GO:0009749 3 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cellular amine metabolic process GO:0044106 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
Human
membrane invagination GO:0010324 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
somite development GO:0061053 96 0.012
meiosis ii GO:0007135 1 0.012
multi organism process GO:0051704 134 0.012
regulation of chromosome segregation GO:0051983 1 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
head development GO:0060322 303 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
lipid storage GO:0019915 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
meiotic cell cycle process GO:1903046 3 0.011
specification of symmetry GO:0009799 204 0.011
phagocytosis engulfment GO:0006911 1 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
amine metabolic process GO:0009308 2 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
regulation of protein targeting GO:1903533 2 0.011
cell migration GO:0016477 237 0.011
glucose homeostasis GO:0042593 1 0.011
positive regulation of cytokine production GO:0001819 2 0.011
regulation of biosynthetic process GO:0009889 250 0.010
Human
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
cellular response to radiation GO:0071478 4 0.010
cell cycle g2 m phase transition GO:0044839 4 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
negative regulation of protein import into nucleus GO:0042308 2 0.010
localization of cell GO:0051674 244 0.010
camera type eye development GO:0043010 222 0.010
mitotic cell cycle embryonic GO:0045448 2 0.010
behavior GO:0007610 74 0.010

med21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.015
disease of anatomical entity DOID:7 0 0.014
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012