Danio rerio

0 known processes

hlfb

hepatic leukemia factor b

(Aliases: hlf2)

hlfb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.056
larval development GO:0002164 2 0.050
regulation of macromolecule metabolic process GO:0060255 317 0.048
sensory organ development GO:0007423 393 0.048
positive regulation of transport GO:0051050 2 0.048
gene expression GO:0010467 252 0.046
regulation of circadian rhythm GO:0042752 4 0.043
establishment of localization GO:0051234 244 0.040
regulation of biological quality GO:0065008 263 0.038
transport GO:0006810 220 0.036
response to chemical GO:0042221 320 0.035
organic cyclic compound metabolic process GO:1901360 301 0.035
nucleic acid templated transcription GO:0097659 181 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
response to uv GO:0009411 3 0.034
organic substance biosynthetic process GO:1901576 289 0.032
amine metabolic process GO:0009308 2 0.032
cellular aromatic compound metabolic process GO:0006725 295 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.031
generation of neurons GO:0048699 385 0.031
ear development GO:0043583 127 0.031
sleep GO:0030431 1 0.030
heterocycle metabolic process GO:0046483 290 0.030
system process GO:0003008 185 0.029
positive regulation of catabolic process GO:0009896 4 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
response to monosaccharide GO:0034284 3 0.029
regulation of metabolic process GO:0019222 359 0.029
regulation of transcription dna templated GO:0006355 213 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
negative regulation of biological process GO:0048519 304 0.028
central nervous system development GO:0007417 387 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
regulation of protein catabolic process GO:0042176 1 0.028
embryonic organ morphogenesis GO:0048562 274 0.027
regulation of metal ion transport GO:0010959 4 0.027
transcription dna templated GO:0006351 181 0.027
response to carbohydrate GO:0009743 3 0.027
multicellular organism growth GO:0035264 4 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
macromolecule biosynthetic process GO:0009059 227 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
cellular amine metabolic process GO:0044106 2 0.026
regulation of protein complex assembly GO:0043254 3 0.026
cell morphogenesis GO:0000902 289 0.025
regulation of gene expression GO:0010468 265 0.025
cellular component disassembly GO:0022411 1 0.025
camera type eye development GO:0043010 222 0.024
cell part morphogenesis GO:0032990 246 0.024
embryonic organ development GO:0048568 381 0.024
rna metabolic process GO:0016070 219 0.024
locomotion GO:0040011 313 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
regulation of rna metabolic process GO:0051252 224 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
cellular ketone metabolic process GO:0042180 11 0.024
axon ensheathment in central nervous system GO:0032291 2 0.024
negative regulation of protein kinase activity GO:0006469 4 0.023
phagocytosis GO:0006909 3 0.023
ion transmembrane transport GO:0034220 91 0.023
negative regulation of cellular process GO:0048523 283 0.023
nuclear migration GO:0007097 3 0.023
meiotic nuclear division GO:0007126 4 0.023
regulation of developmental process GO:0050793 247 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
developmental programmed cell death GO:0010623 4 0.022
brain development GO:0007420 293 0.022
stem cell proliferation GO:0072089 4 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
ion transport GO:0006811 114 0.022
regulation of transmembrane transporter activity GO:0022898 2 0.022
regulation of primary metabolic process GO:0080090 311 0.022
single organism metabolic process GO:0044710 217 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
regulation of ion transmembrane transporter activity GO:0032412 2 0.022
regulation of rna biosynthetic process GO:2001141 213 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
regulation of sodium ion transport GO:0002028 2 0.021
signal transduction GO:0007165 455 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
cellular response to oxygen levels GO:0071453 1 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
regulation of synaptic plasticity GO:0048167 1 0.021
cellular response to light stimulus GO:0071482 4 0.021
inner ear development GO:0048839 126 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
rna biosynthetic process GO:0032774 181 0.020
biosynthetic process GO:0009058 294 0.020
organelle assembly GO:0070925 110 0.020
catecholamine metabolic process GO:0006584 2 0.020
adult behavior GO:0030534 2 0.020
transmembrane transport GO:0055085 120 0.020
regulation of biosynthetic process GO:0009889 250 0.020
cellular biosynthetic process GO:0044249 286 0.020
localization of cell GO:0051674 244 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
protein import GO:0017038 3 0.020
positive regulation of cellular process GO:0048522 201 0.020
organic acid metabolic process GO:0006082 31 0.020
regulation of signal transduction GO:0009966 225 0.020
organelle organization GO:0006996 227 0.020
regulation of cytokine production GO:0001817 3 0.020
cell substrate adhesion GO:0031589 4 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.019
stem cell maintenance GO:0019827 4 0.019
carbon dioxide transport GO:0015670 3 0.019
positive regulation of cell cycle GO:0045787 3 0.019
response to hexose GO:0009746 3 0.019
maintenance of location GO:0051235 4 0.019
atp catabolic process GO:0006200 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
sodium ion transmembrane transport GO:0035725 21 0.018
startle response GO:0001964 4 0.018
protein localization to nucleus GO:0034504 3 0.018
nucleic acid metabolic process GO:0090304 244 0.018
cellular protein catabolic process GO:0044257 4 0.018
single organism transport GO:0044765 206 0.018
protein targeting to nucleus GO:0044744 3 0.018
muscle tissue development GO:0060537 110 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
cellular component assembly GO:0022607 170 0.018
cation transmembrane transport GO:0098655 65 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
cellular component assembly involved in morphogenesis GO:0010927 107 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
neuron development GO:0048666 262 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
tube morphogenesis GO:0035239 349 0.018
leukocyte proliferation GO:0070661 1 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
skin development GO:0043588 54 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
cell projection morphogenesis GO:0048858 244 0.017
regulation of dendrite development GO:0050773 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
sensory system development GO:0048880 76 0.017
positive regulation of cytokine production GO:0001819 2 0.017
neuron projection development GO:0031175 180 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
homeostatic process GO:0042592 142 0.017
heart development GO:0007507 313 0.017
transmission of nerve impulse GO:0019226 19 0.017
response to other organism GO:0051707 97 0.017
head development GO:0060322 303 0.017
negative regulation of mapk cascade GO:0043409 4 0.017
regulation of cell shape GO:0008360 1 0.017
inorganic ion transmembrane transport GO:0098660 57 0.017
axonogenesis GO:0007409 152 0.017
action potential GO:0001508 19 0.017
lens development in camera type eye GO:0002088 22 0.017
organonitrogen compound metabolic process GO:1901564 74 0.016
digestive system development GO:0055123 289 0.016
single organism nuclear import GO:1902593 3 0.016
adherens junction organization GO:0034332 4 0.016
regulation of transporter activity GO:0032409 2 0.016
neuron differentiation GO:0030182 353 0.016
lipid storage GO:0019915 1 0.016
regulation of binding GO:0051098 3 0.016
nuclear transport GO:0051169 4 0.016
cell motility GO:0048870 244 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
response to abiotic stimulus GO:0009628 122 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
response to external stimulus GO:0009605 264 0.016
long chain fatty acid metabolic process GO:0001676 1 0.016
single organism organelle organization GO:1902589 199 0.016
cell migration GO:0016477 237 0.016
neuroblast proliferation GO:0007405 2 0.016
regulation of reproductive process GO:2000241 4 0.016
mesenchymal cell differentiation GO:0048762 87 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
negative regulation of kinase activity GO:0033673 4 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
response to topologically incorrect protein GO:0035966 2 0.015
energy reserve metabolic process GO:0006112 2 0.015
digestive tract morphogenesis GO:0048546 231 0.015
muscle structure development GO:0061061 196 0.015
growth GO:0040007 174 0.015
response to stress GO:0006950 263 0.015
cellular component movement GO:0006928 335 0.015
response to organic substance GO:0010033 153 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
neuronal action potential GO:0019228 18 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
immune system process GO:0002376 241 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
protein metabolic process GO:0019538 183 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
single organism localization GO:1902578 225 0.015
cellular component morphogenesis GO:0032989 336 0.014
vasculature development GO:0001944 278 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
cell projection organization GO:0030030 284 0.014
gtp catabolic process GO:0006184 2 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
monovalent inorganic cation transport GO:0015672 42 0.014
protein localization to plasma membrane GO:0072659 1 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
cognition GO:0050890 1 0.014
chordate embryonic development GO:0043009 271 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
cellular response to organic substance GO:0071310 105 0.014
cellular component biogenesis GO:0044085 178 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
response to alkaloid GO:0043279 2 0.014
mesenchymal cell development GO:0014031 78 0.014
protein dephosphorylation GO:0006470 3 0.014
sodium ion transport GO:0006814 24 0.014
monoamine transport GO:0015844 1 0.013
cation transport GO:0006812 81 0.013
cellular response to radiation GO:0071478 4 0.013
female gonad development GO:0008585 4 0.013
autophagy GO:0006914 4 0.013
protein polymerization GO:0051258 4 0.013
cellular response to hypoxia GO:0071456 1 0.013
regulation of blood vessel size GO:0050880 2 0.013
regulation of ph GO:0006885 3 0.013
neurotransmitter transport GO:0006836 2 0.013
meiotic cell cycle process GO:1903046 3 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
protein complex disassembly GO:0043241 1 0.013
regulation of response to stimulus GO:0048583 269 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
positive regulation of secretion GO:0051047 1 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
eye development GO:0001654 277 0.013
hindbrain development GO:0030902 91 0.013
gtp metabolic process GO:0046039 4 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
peptide transport GO:0015833 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
response to glucose GO:0009749 3 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
multicellular organismal signaling GO:0035637 22 0.013
regionalization GO:0003002 274 0.013
protein import into nucleus GO:0006606 3 0.013
retina development in camera type eye GO:0060041 146 0.013
centrosome cycle GO:0007098 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
sensory organ morphogenesis GO:0090596 200 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
midbrain development GO:0030901 28 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
locomotor rhythm GO:0045475 3 0.012
cilium organization GO:0044782 71 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of blood pressure GO:0008217 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
positive regulation of biological process GO:0048518 253 0.012
secondary metabolic process GO:0019748 3 0.012
response to external biotic stimulus GO:0043207 97 0.012
mesenchyme development GO:0060485 127 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
neurological system process GO:0050877 62 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
stem cell differentiation GO:0048863 117 0.012
response to nutrient GO:0007584 3 0.012
apoptotic process involved in development GO:1902742 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
forebrain development GO:0030900 96 0.012
regulation of synapse assembly GO:0051963 3 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
protein homooligomerization GO:0051260 3 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
pigmentation GO:0043473 85 0.012
regulation of cell communication GO:0010646 232 0.012
regulation of membrane potential GO:0042391 23 0.012
carbohydrate homeostasis GO:0033500 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
gastrulation GO:0007369 208 0.012
urogenital system development GO:0001655 97 0.012
axon development GO:0061564 166 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
muscle cell development GO:0055001 115 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of growth rate GO:0040009 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
organelle fusion GO:0048284 3 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
digestive tract development GO:0048565 265 0.011
mitochondrion organization GO:0007005 4 0.011
blood circulation GO:0008015 87 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
cellular response to external stimulus GO:0071496 2 0.011
nuclear import GO:0051170 3 0.011
regulation of protein binding GO:0043393 3 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
striated muscle tissue development GO:0014706 110 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
positive regulation of metabolic process GO:0009893 108 0.011
response to drug GO:0042493 3 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of cell differentiation GO:0045595 142 0.011
membrane invagination GO:0010324 1 0.011
regulation of signaling GO:0023051 235 0.011
sympathetic nervous system development GO:0048485 3 0.011
regulation of localization GO:0032879 104 0.011
phagocytosis engulfment GO:0006911 1 0.011
neural crest cell differentiation GO:0014033 72 0.011
smooth muscle contraction GO:0006939 2 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
regulation of protein transport GO:0051223 3 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
negative regulation of protein complex assembly GO:0031333 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
response to radiation GO:0009314 51 0.010
thermosensory behavior GO:0040040 1 0.010
regulation of tube size GO:0035150 2 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
medulla oblongata development GO:0021550 4 0.010
compound eye development GO:0048749 2 0.010
cell matrix adhesion GO:0007160 4 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
negative regulation of signaling GO:0023057 96 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
regulation of cell activation GO:0050865 1 0.010
cilium morphogenesis GO:0060271 85 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
regulation of inflammatory response GO:0050727 2 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
stem cell division GO:0017145 1 0.010
centrosome organization GO:0051297 1 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
central nervous system myelination GO:0022010 2 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010

hlfb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.010