Danio rerio

97 known processes

fzd2

frizzled homolog 2

(Aliases: zfz2,fz8,cb383,wu:fb70g09,zg08)

fzd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract morphogenesis GO:0048546 231 0.785
convergent extension GO:0060026 118 0.524
digestive tract development GO:0048565 265 0.516
extracellular structure organization GO:0043062 27 0.397
blood vessel development GO:0001568 246 0.368
response to chemical GO:0042221 320 0.336
Rat
gastrulation GO:0007369 208 0.292
morphogenesis of an epithelium GO:0002009 333 0.287
vasculature development GO:0001944 278 0.283
negative regulation of response to stimulus GO:0048585 104 0.268
Zebrafish
digestive system development GO:0055123 289 0.261
cilium morphogenesis GO:0060271 85 0.259
cell projection morphogenesis GO:0048858 244 0.250
cell motility GO:0048870 244 0.219
neuron development GO:0048666 262 0.200
Mouse
blood vessel morphogenesis GO:0048514 216 0.198
response to nutrient GO:0007584 3 0.189
Rat
connective tissue development GO:0061448 99 0.188
cognition GO:0050890 1 0.183
multicellular organismal macromolecule metabolic process GO:0044259 2 0.181
ameboidal type cell migration GO:0001667 143 0.172
convergent extension involved in gastrulation GO:0060027 71 0.171
response to stress GO:0006950 263 0.169
cell projection organization GO:0030030 284 0.156
fat soluble vitamin metabolic process GO:0006775 4 0.153
cell morphogenesis involved in differentiation GO:0000904 195 0.153
regulation of erk1 and erk2 cascade GO:0070372 4 0.149
tube morphogenesis GO:0035239 349 0.144
regulation of cell differentiation GO:0045595 142 0.142
heart development GO:0007507 313 0.132
multicellular organismal metabolic process GO:0044236 2 0.128
angiogenesis GO:0001525 158 0.127
regeneration GO:0031099 91 0.126
single organism metabolic process GO:0044710 217 0.124
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.119
organic substance biosynthetic process GO:1901576 289 0.114
negative regulation of multicellular organismal process GO:0051241 69 0.113
regulation of cellular component organization GO:0051128 86 0.113
cellular component morphogenesis GO:0032989 336 0.113
neuron projection guidance GO:0097485 86 0.109
regulation of cellular component movement GO:0051270 55 0.106
regulation of cellular amine metabolic process GO:0033238 0 0.105
axon regeneration GO:0031103 14 0.105
cartilage condensation GO:0001502 3 0.102
system process GO:0003008 185 0.102
Mouse
cell migration involved in gastrulation GO:0042074 79 0.102
anterior posterior pattern specification GO:0009952 152 0.101
adherens junction organization GO:0034332 4 0.100
hematopoietic or lymphoid organ development GO:0048534 191 0.099
bleb assembly GO:0032060 1 0.099
cilium assembly GO:0042384 58 0.097
defense response GO:0006952 47 0.094
localization of cell GO:0051674 244 0.090
regulation of multicellular organismal development GO:2000026 223 0.089
Mouse
cellular protein catabolic process GO:0044257 4 0.088
erk1 and erk2 cascade GO:0070371 4 0.087
embryo development ending in birth or egg hatching GO:0009792 271 0.085
Mouse
muscle structure development GO:0061061 196 0.084
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.083
chemosensory behavior GO:0007635 1 0.082
organic cyclic compound biosynthetic process GO:1901362 223 0.081
cellular amine metabolic process GO:0044106 2 0.081
positive regulation of cell adhesion GO:0045785 1 0.081
negative regulation of developmental growth GO:0048640 9 0.080
formation of primary germ layer GO:0001704 62 0.080
cell substrate adhesion GO:0031589 4 0.080
nucleocytoplasmic transport GO:0006913 4 0.078
muscle cell development GO:0055001 115 0.077
muscle tissue development GO:0060537 110 0.074
eye development GO:0001654 277 0.074
Zebrafish
regulation of synapse organization GO:0050807 3 0.074
negative regulation of signaling GO:0023057 96 0.073
Zebrafish
regulation of binding GO:0051098 3 0.070
regulation of response to stimulus GO:0048583 269 0.070
Zebrafish
cell adhesion GO:0007155 40 0.070
cilium organization GO:0044782 71 0.069
skeletal system development GO:0001501 181 0.068
taxis GO:0042330 109 0.068
endodermal cell differentiation GO:0035987 19 0.067
response to biotic stimulus GO:0009607 97 0.067
collagen metabolic process GO:0032963 2 0.067
cartilage development GO:0051216 96 0.067
regulation of hormone secretion GO:0046883 2 0.066
cellular amino acid metabolic process GO:0006520 7 0.066
generation of neurons GO:0048699 385 0.065
Zebrafish Mouse
cell projection assembly GO:0030031 64 0.065
endocardial cushion formation GO:0003272 2 0.065
striated muscle cell development GO:0055002 108 0.064
cell part morphogenesis GO:0032990 246 0.064
sensory organ development GO:0007423 393 0.064
Zebrafish Mouse
radial glial cell differentiation GO:0060019 2 0.064
Zebrafish
cellular protein modification process GO:0006464 100 0.063
regulation of protein binding GO:0043393 3 0.062
mesenchyme development GO:0060485 127 0.062
cardiac cell development GO:0055006 21 0.058
chondrocyte development GO:0002063 4 0.057
regulation of innate immune response GO:0045088 11 0.057
neuron projection regeneration GO:0031102 16 0.057
amine metabolic process GO:0009308 2 0.057
carboxylic acid metabolic process GO:0019752 22 0.057
neurological system process GO:0050877 62 0.056
Mouse
hepaticobiliary system development GO:0061008 98 0.056
Zebrafish
muscle organ development GO:0007517 101 0.054
Mouse
positive regulation of transport GO:0051050 2 0.053
osteoclast differentiation GO:0030316 1 0.052
axon development GO:0061564 166 0.052
positive regulation of defense response GO:0031349 9 0.052
regulation of epithelial cell proliferation GO:0050678 3 0.051
developmental growth GO:0048589 166 0.051
cell migration GO:0016477 237 0.050
canonical wnt signaling pathway GO:0060070 48 0.050
Zebrafish
sensory perception GO:0007600 39 0.050
Mouse
locomotion GO:0040011 313 0.049
stem cell division GO:0017145 1 0.049
cellular response to chemical stimulus GO:0070887 157 0.049
Rat
response to corticosteroid GO:0031960 1 0.048
notochord development GO:0030903 54 0.048
regulation of stem cell proliferation GO:0072091 2 0.048
gland development GO:0048732 143 0.047
Zebrafish
ubiquitin dependent protein catabolic process GO:0006511 3 0.047
oocyte axis specification GO:0007309 5 0.047
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
regulation of cell development GO:0060284 100 0.046
apoptotic process GO:0006915 116 0.046
cell cell junction organization GO:0045216 10 0.046
epithelial tube morphogenesis GO:0060562 148 0.046
negative regulation of myeloid cell differentiation GO:0045638 1 0.046
cell morphogenesis GO:0000902 289 0.046
extrinsic apoptotic signaling pathway GO:0097191 3 0.045
stem cell proliferation GO:0072089 4 0.045
epithelium migration GO:0090132 25 0.045
protein metabolic process GO:0019538 183 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.044
regulation of inflammatory response GO:0050727 2 0.044
multicellular organismal signaling GO:0035637 22 0.043
regulation of cell activation GO:0050865 1 0.043
negative regulation of signal transduction GO:0009968 94 0.043
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.043
Rat
regulation of cell migration GO:0030334 40 0.042
cell surface receptor signaling pathway GO:0007166 325 0.042
negative regulation of protein phosphorylation GO:0001933 4 0.041
modification dependent macromolecule catabolic process GO:0043632 3 0.040
response to mercury ion GO:0046689 1 0.040
positive regulation of stem cell proliferation GO:2000648 1 0.040
single organism cell adhesion GO:0098602 29 0.040
negative regulation of cell communication GO:0010648 96 0.040
Zebrafish
response to external stimulus GO:0009605 264 0.039
Rat
positive regulation of protein deacetylation GO:0090312 1 0.039
regulation of signal transduction GO:0009966 225 0.039
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.039
regulation of nervous system development GO:0051960 90 0.038
Mouse
protein localization to plasma membrane GO:0072659 1 0.038
regulation of developmental process GO:0050793 247 0.038
Mouse
proteolysis GO:0006508 38 0.038
sensory perception of light stimulus GO:0050953 19 0.037
germ line stem cell maintenance GO:0030718 2 0.037
fat soluble vitamin biosynthetic process GO:0042362 2 0.037
single fertilization GO:0007338 3 0.037
immune response GO:0006955 28 0.037
spermatid development GO:0007286 2 0.037
single organismal cell cell adhesion GO:0016337 29 0.037
regulation of chondrocyte differentiation GO:0032330 1 0.036
cellular component biogenesis GO:0044085 178 0.036
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.036
cell fate commitment GO:0045165 99 0.036
Zebrafish
endodermal cell fate commitment GO:0001711 18 0.036
cell growth GO:0016049 57 0.036
multi organism process GO:0051704 134 0.035
regulation of cytoplasmic transport GO:1903649 4 0.035
immune system process GO:0002376 241 0.035
negative regulation of epithelial cell proliferation GO:0050680 1 0.035
phosphorylation GO:0016310 69 0.035
rna biosynthetic process GO:0032774 181 0.035
biological adhesion GO:0022610 40 0.034
endoderm development GO:0007492 49 0.034
cellular response to lipopolysaccharide GO:0071222 3 0.034
somite development GO:0061053 96 0.034
rna localization GO:0006403 4 0.034
response to wounding GO:0009611 116 0.034
negative regulation of cell differentiation GO:0045596 46 0.034
phagocytosis GO:0006909 3 0.033
epithelial cell morphogenesis GO:0003382 2 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.033
mesenchymal cell proliferation GO:0010463 1 0.033
epithelial to mesenchymal transition GO:0001837 21 0.032
tight junction assembly GO:0070830 1 0.032
oxidoreduction coenzyme metabolic process GO:0006733 1 0.032
protein targeting to nucleus GO:0044744 3 0.031
stem cell maintenance GO:0019827 4 0.031
endoderm formation GO:0001706 29 0.031
segmentation GO:0035282 97 0.031
cell junction organization GO:0034330 11 0.031
growth GO:0040007 174 0.030
neuron projection development GO:0031175 180 0.030
positive regulation of stress activated mapk cascade GO:0032874 3 0.030
positive regulation of chromatin modification GO:1903310 1 0.030
positive regulation of cell activation GO:0050867 1 0.030
protein modification process GO:0036211 100 0.030
gliogenesis GO:0042063 45 0.030
Zebrafish
regulation of biological quality GO:0065008 263 0.030
Rat
transcription from rna polymerase iii promoter GO:0006383 1 0.029
negative regulation of developmental process GO:0051093 65 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
response to glucocorticoid GO:0051384 1 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
extracellular matrix organization GO:0030198 27 0.029
regulation of synapse assembly GO:0051963 3 0.028
regulation of cell motility GO:2000145 46 0.028
regionalization GO:0003002 274 0.028
Zebrafish
positive regulation of wound healing GO:0090303 1 0.028
epithelial cell migration GO:0010631 25 0.028
detection of abiotic stimulus GO:0009582 24 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.028
regulation of wnt signaling pathway GO:0030111 53 0.028
Zebrafish
hemopoiesis GO:0030097 183 0.028
macromolecule modification GO:0043412 111 0.027
mesenchymal cell development GO:0014031 78 0.027
regulation of proteolysis GO:0030162 24 0.027
regulation of canonical wnt signaling pathway GO:0060828 34 0.026
Zebrafish
positive regulation of chromosome organization GO:2001252 1 0.026
ceramide biosynthetic process GO:0046513 1 0.026
lens fiber cell morphogenesis GO:0070309 3 0.026
negative regulation of intracellular transport GO:0032387 3 0.026
positive regulation of blood circulation GO:1903524 2 0.026
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.026
response to vitamin GO:0033273 3 0.026
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
positive regulation of cellular process GO:0048522 201 0.025
nuclear import GO:0051170 3 0.025
formation of anatomical boundary GO:0048859 14 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
positive regulation of developmental process GO:0051094 50 0.025
chemotaxis GO:0006935 104 0.025
optic placode formation involved in camera type eye formation GO:0046619 3 0.025
Zebrafish
positive regulation of cell differentiation GO:0045597 30 0.025
vitamin biosynthetic process GO:0009110 2 0.024
defense response to fungus GO:0050832 2 0.024
heart process GO:0003015 71 0.024
regulation of chemotaxis GO:0050920 18 0.024
positive regulation of innate immune response GO:0045089 8 0.024
larval development GO:0002164 2 0.024
regulation of organ growth GO:0046620 3 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
regulation of response to stress GO:0080134 36 0.023
regulation of histone deacetylation GO:0031063 2 0.023
peptidyl serine phosphorylation GO:0018105 1 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.023
axon extension GO:0048675 45 0.023
cellular component movement GO:0006928 335 0.023
oocyte differentiation GO:0009994 14 0.023
cardiac atrium morphogenesis GO:0003209 2 0.022
cell substrate junction assembly GO:0007044 2 0.022
skeletal muscle organ development GO:0060538 78 0.022
positive regulation of protein kinase b signaling GO:0051897 1 0.022
regulation of intracellular signal transduction GO:1902531 57 0.022
positive regulation of histone modification GO:0031058 1 0.022
cell chemotaxis GO:0060326 17 0.022
compound eye development GO:0048749 2 0.022
negative regulation of cellular component organization GO:0051129 16 0.022
regulation of natural killer cell mediated immunity GO:0002715 1 0.021
multicellular organism growth GO:0035264 4 0.021
lipid storage GO:0019915 1 0.021
establishment of localization GO:0051234 244 0.021
response to organic cyclic compound GO:0014070 51 0.021
Rat
regulation of cell communication GO:0010646 232 0.021
Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.021
chordate embryonic development GO:0043009 271 0.021
Mouse
head development GO:0060322 303 0.021
Zebrafish
negative regulation of leukocyte differentiation GO:1902106 1 0.021
regulation of receptor mediated endocytosis GO:0048259 4 0.020
glial cell migration GO:0008347 3 0.020
regulation of localization GO:0032879 104 0.020
transmission of nerve impulse GO:0019226 19 0.020
sprouting angiogenesis GO:0002040 53 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
peptide transport GO:0015833 1 0.020
regulation of locomotion GO:0040012 55 0.020
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
regulation of neurogenesis GO:0050767 87 0.020
cell adhesion mediated by integrin GO:0033627 1 0.020
response to growth factor GO:0070848 39 0.020
Rat
regulation of blood vessel size GO:0050880 2 0.019
neuron projection morphogenesis GO:0048812 161 0.019
regulation of growth GO:0040008 42 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
negative regulation of reproductive process GO:2000242 3 0.019
axonogenesis GO:0007409 152 0.019
regulation of catenin import into nucleus GO:0035412 2 0.019
establishment of protein localization to plasma membrane GO:0090002 1 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of developmental growth GO:0048638 38 0.019
negative regulation of response to dna damage stimulus GO:2001021 3 0.019
regulation of organelle organization GO:0033043 29 0.018
lymph vessel development GO:0001945 27 0.018
basement membrane organization GO:0071711 5 0.018
regulation of cell projection assembly GO:0060491 4 0.018
positive regulation of neuron projection development GO:0010976 9 0.018
regulation of protein transport GO:0051223 3 0.018
regulation of mapk cascade GO:0043408 14 0.018
craniofacial suture morphogenesis GO:0097094 2 0.018
response to decreased oxygen levels GO:0036293 25 0.018
regulation of establishment of planar polarity GO:0090175 4 0.018
Mouse
negative regulation of dna replication GO:0008156 2 0.018
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.018
embryonic skeletal system development GO:0048706 97 0.018
regulation of cell projection organization GO:0031344 44 0.018
branching morphogenesis of a nerve GO:0048755 4 0.018
optic placode formation GO:0001743 4 0.018
Zebrafish
regulation of cell substrate adhesion GO:0010810 1 0.017
intramembranous ossification GO:0001957 3 0.017
developmental cell growth GO:0048588 52 0.017
organelle organization GO:0006996 227 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
regulation of cell growth GO:0001558 29 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
innate immune response GO:0045087 13 0.017
spinal cord radial glial cell differentiation GO:0021531 2 0.017
Zebrafish
negative regulation of chemotaxis GO:0050922 4 0.017
axon guidance GO:0007411 86 0.017
cellular response to lipid GO:0071396 39 0.017
Rat
positive regulation of neurogenesis GO:0050769 24 0.017
cellular component assembly GO:0022607 170 0.017
innate immune response activating signal transduction GO:0002758 5 0.016
positive regulation of epithelial cell proliferation GO:0050679 1 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
neuron differentiation GO:0030182 353 0.016
Zebrafish Mouse
visual perception GO:0007601 17 0.016
appendage morphogenesis GO:0035107 56 0.016
regulation of neuron projection development GO:0010975 40 0.016
apical junction assembly GO:0043297 1 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
dorsal ventral pattern formation GO:0009953 125 0.016
Zebrafish
heart morphogenesis GO:0003007 156 0.016
kidney development GO:0001822 92 0.016
regulation of reproductive process GO:2000241 4 0.016
behavior GO:0007610 74 0.016
oxoacid metabolic process GO:0043436 31 0.016
oocyte development GO:0048599 14 0.016
heterocycle metabolic process GO:0046483 290 0.016
organic acid metabolic process GO:0006082 31 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
positive regulation of mesoderm development GO:2000382 1 0.016
multicellular organismal reproductive process GO:0048609 35 0.016
muscle cell differentiation GO:0042692 139 0.016
positive regulation of histone deacetylation GO:0031065 1 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
mesenchymal cell differentiation GO:0048762 87 0.015
regulation of cellular component size GO:0032535 30 0.015
positive regulation of biological process GO:0048518 253 0.015
embryonic organ development GO:0048568 381 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
lateral inhibition GO:0046331 1 0.015
ras protein signal transduction GO:0007265 7 0.015
carbohydrate homeostasis GO:0033500 1 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
cell recognition GO:0008037 19 0.015
positive regulation of chronic inflammatory response GO:0002678 1 0.015
endocardial cushion morphogenesis GO:0003203 3 0.015
response to monosaccharide GO:0034284 3 0.015
response to drug GO:0042493 3 0.015
rna metabolic process GO:0016070 219 0.015
protein import into nucleus GO:0006606 3 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
aging GO:0007568 2 0.014
negative regulation of signal transduction by p53 class mediator GO:1901797 8 0.014
retina layer formation GO:0010842 24 0.014
positive regulation of locomotion GO:0040017 14 0.014
lamellipodium assembly GO:0030032 1 0.014
rho protein signal transduction GO:0007266 5 0.014
single organism behavior GO:0044708 24 0.014
regulation of cell shape GO:0008360 1 0.014
cell aggregation GO:0098743 3 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
catenin import into nucleus GO:0035411 2 0.014
regulation of mesenchymal cell proliferation GO:0010464 1 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
immune system development GO:0002520 191 0.014
peptidyl serine modification GO:0018209 2 0.013
response to other organism GO:0051707 97 0.013
hindbrain development GO:0030902 91 0.013
Zebrafish
endothelial cell migration GO:0043542 19 0.013
neuronal action potential GO:0019228 18 0.013
negative regulation of wnt signaling pathway GO:0030178 30 0.013
Zebrafish
oocyte construction GO:0007308 5 0.013
appendage development GO:0048736 80 0.013
transport GO:0006810 220 0.013
regulation of metal ion transport GO:0010959 4 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
cardiac muscle tissue development GO:0048738 48 0.013
regulation of organ morphogenesis GO:2000027 35 0.013
Mouse
post embryonic organ development GO:0048569 4 0.013
convergent extension involved in axis elongation GO:0060028 26 0.013
cell death GO:0008219 121 0.013
liver development GO:0001889 96 0.013
Zebrafish
bone remodeling GO:0046849 2 0.013
endothelial cell morphogenesis GO:0001886 1 0.013
response to abiotic stimulus GO:0009628 122 0.013
death GO:0016265 121 0.013
regulation of dendrite development GO:0050773 3 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
cellular response to organic substance GO:0071310 105 0.013
Rat
negative regulation of cellular process GO:0048523 283 0.013
Zebrafish
negative regulation of growth GO:0045926 10 0.013
nuclear transport GO:0051169 4 0.012
regulation of primary metabolic process GO:0080090 311 0.012
cardiac atrium development GO:0003230 4 0.012
organelle assembly GO:0070925 110 0.012
smoothened signaling pathway GO:0007224 30 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
negative regulation of molecular function GO:0044092 23 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
regulation of cell death GO:0010941 103 0.012
neuroblast proliferation GO:0007405 2 0.012
skeletal system morphogenesis GO:0048705 102 0.012
detection of external stimulus GO:0009581 24 0.012
tissue remodeling GO:0048771 4 0.012
melanin metabolic process GO:0006582 2 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
maintenance of location GO:0051235 4 0.012
proepicardium development GO:0003342 4 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
response to organic substance GO:0010033 153 0.012
Rat
axonal defasciculation GO:0007414 2 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
negative regulation of behavior GO:0048521 6 0.012
medial fin development GO:0033338 16 0.012
single organism reproductive process GO:0044702 40 0.012
striated muscle tissue development GO:0014706 110 0.012
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.012
regulation of membrane potential GO:0042391 23 0.012
pericardium morphogenesis GO:0003344 1 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
protein deacetylation GO:0006476 3 0.012
response to fungus GO:0009620 25 0.012
regulation of neuron differentiation GO:0045664 56 0.011
negative regulation of multi organism process GO:0043901 3 0.011
somitogenesis GO:0001756 87 0.011
response to steroid hormone GO:0048545 35 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.011
negative regulation of endodermal cell differentiation GO:1903225 8 0.011
eye morphogenesis GO:0048592 144 0.011
Zebrafish
response to external biotic stimulus GO:0043207 97 0.011
regulation of rna metabolic process GO:0051252 224 0.011
negative regulation of metabolic process GO:0009892 86 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of protein modification process GO:0031399 29 0.011
protein import GO:0017038 3 0.011
peptidyl amino acid modification GO:0018193 16 0.011
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
renal system vasculature development GO:0061437 2 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
striated muscle cell differentiation GO:0051146 129 0.011
lens fiber cell development GO:0070307 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
regulation of metabolic process GO:0019222 359 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
regulation of dna replication GO:0006275 3 0.011
positive regulation of secretion GO:0051047 1 0.011
hormone secretion GO:0046879 2 0.011
epithelial cell development GO:0002064 42 0.011
regulation of behavior GO:0050795 24 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
modification of morphology or physiology of other organism GO:0035821 4 0.011
regulation of protein targeting GO:1903533 2 0.011
single organism nuclear import GO:1902593 3 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
septum transversum development GO:0003343 4 0.011
secondary metabolic process GO:0019748 3 0.011
neural crest cell development GO:0014032 62 0.011
heart jogging GO:0003146 40 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
regulation of protein kinase b signaling GO:0051896 8 0.010

fzd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.212
disease of mental health DOID:150 0 0.030
developmental disorder of mental health DOID:0060037 0 0.030
artery disease DOID:0050828 0 0.025
vascular disease DOID:178 0 0.025
cardiovascular system disease DOID:1287 0 0.025
disease of cellular proliferation DOID:14566 0 0.018
nervous system disease DOID:863 0 0.018
gastrointestinal system cancer DOID:3119 0 0.015
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
osteochondrodysplasia DOID:2256 0 0.014
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
disease of metabolism DOID:0014667 0 0.013