Danio rerio

43 known processes

fzd5

frizzled homolog 5

(Aliases: fz2,fzd8c,zg02,fz8c)

fzd5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 244 0.952
Zebrafish Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.927
Human Mouse
localization of cell GO:0051674 244 0.878
Zebrafish Fly
cellular component morphogenesis GO:0032989 336 0.838
Zebrafish Fly
cell morphogenesis GO:0000902 289 0.811
Zebrafish Fly
brain development GO:0007420 293 0.768
Zebrafish
digestive tract development GO:0048565 265 0.763
Zebrafish
cell migration GO:0016477 237 0.759
Zebrafish Fly
central nervous system development GO:0007417 387 0.752
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.740
Human Mouse
regulation of biosynthetic process GO:0009889 250 0.691
Human Mouse
digestive tract morphogenesis GO:0048546 231 0.683
Zebrafish
regionalization GO:0003002 274 0.681
Human Zebrafish
sensory organ development GO:0007423 393 0.679
Zebrafish Mouse Fly
regulation of signaling GO:0023051 235 0.662
cellular biosynthetic process GO:0044249 286 0.649
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.642
Human Mouse
regulation of primary metabolic process GO:0080090 311 0.639
Human Mouse
regulation of cell communication GO:0010646 232 0.636
negative regulation of biological process GO:0048519 304 0.630
cellular component movement GO:0006928 335 0.628
Zebrafish Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.621
Mouse
digestive system development GO:0055123 289 0.613
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.611
Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.610
Human Mouse
camera type eye development GO:0043010 222 0.608
Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.602
Human Mouse
negative regulation of response to stimulus GO:0048585 104 0.600
regulation of signal transduction GO:0009966 225 0.594
cell part morphogenesis GO:0032990 246 0.594
Zebrafish Fly
locomotion GO:0040011 313 0.579
Zebrafish Fly
dorsal ventral pattern formation GO:0009953 125 0.568
Human Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.563
Human Mouse
gastrulation GO:0007369 208 0.563
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.561
Human Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.559
heterocycle metabolic process GO:0046483 290 0.557
Human Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.553
Human Mouse
eye development GO:0001654 277 0.546
Zebrafish Mouse
neuron development GO:0048666 262 0.544
Fly
regulation of embryonic development GO:0045995 47 0.536
tube morphogenesis GO:0035239 349 0.533
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.533
Human Mouse
rna metabolic process GO:0016070 219 0.530
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.522
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.521
positive regulation of biological process GO:0048518 253 0.518
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.500
Human Mouse
heart looping GO:0001947 94 0.495
Zebrafish
regulation of gene expression GO:0010468 265 0.490
Human Mouse
heart morphogenesis GO:0003007 156 0.479
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.477
Human Mouse
response to stress GO:0006950 263 0.465
Zebrafish Mouse
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.463
neuron projection development GO:0031175 180 0.458
Fly
regulation of metabolic process GO:0019222 359 0.458
Human Mouse
ameboidal type cell migration GO:0001667 143 0.456
cell surface receptor signaling pathway GO:0007166 325 0.454
heart development GO:0007507 313 0.452
Zebrafish
formation of primary germ layer GO:0001704 62 0.441
oocyte maturation GO:0001556 4 0.440
regulation of canonical wnt signaling pathway GO:0060828 34 0.436
heart jogging GO:0003146 40 0.433
Zebrafish
axon guidance GO:0007411 86 0.419
Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.417
protein metabolic process GO:0019538 183 0.417
Mouse
regulation of response to stimulus GO:0048583 269 0.412
central nervous system neuron differentiation GO:0021953 74 0.406
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.403
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.399
Human Mouse
neuron differentiation GO:0030182 353 0.399
Zebrafish Fly
somitogenesis GO:0001756 87 0.399
nucleic acid templated transcription GO:0097659 181 0.394
Human Mouse
defense response GO:0006952 47 0.391
regulation of transcription dna templated GO:0006355 213 0.380
Human Mouse
convergent extension GO:0060026 118 0.372
Zebrafish
gland development GO:0048732 143 0.371
gene expression GO:0010467 252 0.369
Human Mouse
cell projection morphogenesis GO:0048858 244 0.362
Zebrafish Fly
immune system development GO:0002520 191 0.361
Mouse
positive regulation of metabolic process GO:0009893 108 0.360
Human Mouse
positive regulation of cellular process GO:0048522 201 0.356
Human Mouse
axon development GO:0061564 166 0.351
Fly
retina development in camera type eye GO:0060041 146 0.349
determination of left right symmetry GO:0007368 179 0.347
Zebrafish
signal transduction GO:0007165 455 0.341
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.339
single organism transport GO:0044765 206 0.335
response to organic substance GO:0010033 153 0.332
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.328
Human Mouse
cellular response to organic substance GO:0071310 105 0.323
cell projection organization GO:0030030 284 0.317
Zebrafish Fly
heterocycle biosynthetic process GO:0018130 215 0.314
Human Mouse
larval development GO:0002164 2 0.311
negative regulation of neuron projection regeneration GO:0070571 4 0.310
regulation of axonogenesis GO:0050770 32 0.303
myeloid cell differentiation GO:0030099 86 0.301
embryonic heart tube morphogenesis GO:0003143 108 0.294
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.294
Human Mouse
regulation of developmental process GO:0050793 247 0.283
Fly
epithelial tube morphogenesis GO:0060562 148 0.282
Zebrafish
negative regulation of wnt signaling pathway GO:0030178 30 0.281
axonogenesis GO:0007409 152 0.281
Fly
nitrogen compound metabolic process GO:0006807 319 0.279
Human Mouse
cellular protein modification process GO:0006464 100 0.276
Mouse
regulation of axon extension GO:0030516 24 0.276
biosynthetic process GO:0009058 294 0.271
Human Mouse
diencephalon development GO:0021536 58 0.271
embryonic camera type eye development GO:0031076 29 0.270
Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.264
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.264
Human Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.263
Zebrafish
ear morphogenesis GO:0042471 64 0.262
negative regulation of axon regeneration GO:0048681 4 0.260
determination of heart left right asymmetry GO:0061371 117 0.253
Zebrafish
female sex differentiation GO:0046660 4 0.250
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.246
Human Mouse
protein localization to nucleus GO:0034504 3 0.241
lateral inhibition GO:0046331 1 0.237
regulation of epithelial cell proliferation GO:0050678 3 0.237
endoderm formation GO:0001706 29 0.236
positive regulation of cellular biosynthetic process GO:0031328 68 0.236
Human Mouse
cellular response to external stimulus GO:0071496 2 0.230
cartilage development GO:0051216 96 0.229
negative regulation of signal transduction GO:0009968 94 0.228
regulation of multicellular organismal process GO:0051239 277 0.224
Human Fly
response to lipid GO:0033993 60 0.224
regulation of cellular protein metabolic process GO:0032268 52 0.218
Mouse
positive regulation of cell cycle GO:0045787 3 0.211
positive regulation of rna biosynthetic process GO:1902680 57 0.210
Human Mouse
transcription dna templated GO:0006351 181 0.209
Human Mouse
convergent extension involved in gastrulation GO:0060027 71 0.209
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.207
Human Mouse
cellular response to extracellular stimulus GO:0031668 2 0.206
regulation of wnt signaling pathway GO:0030111 53 0.205
immune system process GO:0002376 241 0.201
Mouse Fly
regulation of protein metabolic process GO:0051246 56 0.196
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.195
Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.195
endodermal cell fate specification GO:0001714 17 0.194
negative regulation of macromolecule metabolic process GO:0010605 76 0.193
cellular nitrogen compound biosynthetic process GO:0044271 218 0.190
Human Mouse
kidney development GO:0001822 92 0.188
stem cell maintenance GO:0019827 4 0.185
cellular nitrogen compound metabolic process GO:0034641 290 0.185
Human Mouse
skeletal system development GO:0001501 181 0.184
regulation of rna metabolic process GO:0051252 224 0.182
Human Mouse
gastrulation with mouth forming second GO:0001702 44 0.182
regulation of molecular function GO:0065009 70 0.181
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.178
cellular protein metabolic process GO:0044267 129 0.175
Mouse
rhombomere development GO:0021546 19 0.173
negative regulation of developmental process GO:0051093 65 0.173
cellular response to endogenous stimulus GO:0071495 68 0.173
cellular component assembly GO:0022607 170 0.173
Zebrafish Mouse
organic cyclic compound metabolic process GO:1901360 301 0.171
Human Mouse
single organism localization GO:1902578 225 0.169
muscle structure development GO:0061061 196 0.167
regulation of endodermal cell fate specification GO:0042663 15 0.166
negative regulation of gene expression GO:0010629 65 0.166
somite development GO:0061053 96 0.165
head development GO:0060322 303 0.165
Zebrafish
regulation of oocyte development GO:0060281 3 0.164
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.164
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.163
cell fate commitment GO:0045165 99 0.162
Human Zebrafish
intracellular receptor signaling pathway GO:0030522 30 0.161
bmp signaling pathway involved in heart jogging GO:0003303 14 0.161
negative regulation of metabolic process GO:0009892 86 0.159
homeostatic process GO:0042592 142 0.159
cell migration involved in gastrulation GO:0042074 79 0.158
response to growth factor GO:0070848 39 0.157
response to wounding GO:0009611 116 0.156
Zebrafish
forebrain regionalization GO:0021871 4 0.156
leukocyte differentiation GO:0002521 25 0.156
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.154
Mouse
phosphorylation GO:0016310 69 0.151
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.150
Human Mouse
multicellular organism growth GO:0035264 4 0.150
regulation of response to nutrient levels GO:0032107 1 0.148
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.148
Human Mouse
regulation of dna replication GO:0006275 3 0.148
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.148
Mouse
establishment of localization GO:0051234 244 0.148
Fly
embryonic pattern specification GO:0009880 44 0.148
Human
generation of neurons GO:0048699 385 0.147
Zebrafish Fly
negative regulation of signaling GO:0023057 96 0.145
photoreceptor cell fate commitment GO:0046552 1 0.145
ventral spinal cord development GO:0021517 35 0.145
blood vessel morphogenesis GO:0048514 216 0.144
Mouse
negative regulation of cellular process GO:0048523 283 0.143
regulation of reproductive process GO:2000241 4 0.142
retina morphogenesis in camera type eye GO:0060042 79 0.140
hemopoiesis GO:0030097 183 0.138
Mouse
neural tube development GO:0021915 62 0.136
cardiogenic plate morphogenesis GO:0003142 1 0.133
response to chemical GO:0042221 320 0.133
Human Fly
wnt signaling pathway GO:0016055 80 0.133
protein modification process GO:0036211 100 0.133
Mouse
regulation of protein targeting GO:1903533 2 0.133
nucleobase containing compound biosynthetic process GO:0034654 205 0.131
Human Mouse
negative regulation of mesodermal cell fate specification GO:0042662 3 0.131
regulation of localization GO:0032879 104 0.130
negative regulation of protein phosphorylation GO:0001933 4 0.130
negative regulation of transcription dna templated GO:0045892 45 0.129
single organism metabolic process GO:0044710 217 0.128
Mouse
response to abiotic stimulus GO:0009628 122 0.128
nuclear transport GO:0051169 4 0.127
protein import GO:0017038 3 0.126
regulation of circadian rhythm GO:0042752 4 0.126
lymphocyte differentiation GO:0030098 9 0.124
Mouse
autophagy GO:0006914 4 0.124
regulation of protein localization to nucleus GO:1900180 2 0.121
negative regulation of cellular component organization GO:0051129 16 0.120
hormone metabolic process GO:0042445 19 0.120
enzyme linked receptor protein signaling pathway GO:0007167 106 0.120
mesenchyme development GO:0060485 127 0.120
foregut morphogenesis GO:0007440 4 0.120
forebrain development GO:0030900 96 0.119
Zebrafish
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.119
camera type eye morphogenesis GO:0048593 108 0.118
Zebrafish
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.118
rhombomere boundary formation GO:0021654 10 0.116
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.114
fin development GO:0033333 77 0.113
protein import into nucleus GO:0006606 3 0.113
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.113
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.112
positive regulation of map kinase activity GO:0043406 3 0.112
Mouse
regulation of cellular component size GO:0032535 30 0.112
blood vessel development GO:0001568 246 0.111
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.110
Human Mouse
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.109
aging GO:0007568 2 0.109
anterior posterior pattern specification GO:0009952 152 0.108
Human
melanin metabolic process GO:0006582 2 0.107
epidermis development GO:0008544 48 0.105
cellular aromatic compound metabolic process GO:0006725 295 0.105
Human Mouse
cellular response to growth factor stimulus GO:0071363 39 0.104
glial cell fate specification GO:0021780 4 0.104
mesenchymal cell development GO:0014031 78 0.104
regulation of cell development GO:0060284 100 0.102
developmental growth GO:0048589 166 0.101
Zebrafish Fly
renal system development GO:0072001 94 0.100
macromolecule biosynthetic process GO:0009059 227 0.100
Human Mouse
establishment of localization in cell GO:0051649 77 0.100
embryonic heart tube development GO:0035050 133 0.100
Zebrafish
regulation of biological quality GO:0065008 263 0.097
embryonic pectoral fin morphogenesis GO:0035118 24 0.097
response to vitamin GO:0033273 3 0.095
regulation of jun kinase activity GO:0043506 3 0.095
Mouse
compound eye development GO:0048749 2 0.093
regulation of gastrulation GO:0010470 24 0.092
chordate embryonic development GO:0043009 271 0.091
Mouse
establishment of protein localization to organelle GO:0072594 4 0.091
secondary metabolic process GO:0019748 3 0.091
positive regulation of stress activated mapk cascade GO:0032874 3 0.090
Mouse
regulation of stem cell differentiation GO:2000736 4 0.089
negative regulation of cell development GO:0010721 26 0.089
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.089
cellular response to nutrient levels GO:0031669 2 0.088
endocrine system development GO:0035270 65 0.087
Zebrafish
spinal cord motor neuron differentiation GO:0021522 26 0.087
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.086
regulation of cytoplasmic transport GO:1903649 4 0.086
cellular component biogenesis GO:0044085 178 0.086
Zebrafish Mouse
regulation of apoptotic process GO:0042981 98 0.086
notochord development GO:0030903 54 0.085
embryonic cranial skeleton morphogenesis GO:0048701 90 0.085
myotube differentiation GO:0014902 45 0.084
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.083
regulation of nervous system development GO:0051960 90 0.083
regulation of cell differentiation GO:0045595 142 0.082
cellular response to chemical stimulus GO:0070887 157 0.082
taxis GO:0042330 109 0.082
Fly
angiogenesis GO:0001525 158 0.082
Mouse
protein phosphorylation GO:0006468 47 0.081
Mouse
developmental pigmentation GO:0048066 48 0.081
cell differentiation in spinal cord GO:0021515 40 0.080
Zebrafish
liver development GO:0001889 96 0.080
negative regulation of collateral sprouting GO:0048671 2 0.080
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.079
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.079
Human Mouse
lipid storage GO:0019915 1 0.079
stem cell development GO:0048864 82 0.079
regulation of intracellular signal transduction GO:1902531 57 0.078
Mouse
negative regulation of cell differentiation GO:0045596 46 0.078
regulation of cellular component organization GO:0051128 86 0.078
Mouse
regulation of intracellular protein transport GO:0033157 3 0.078
negative regulation of protein transport GO:0051224 3 0.078
negative regulation of multicellular organismal process GO:0051241 69 0.077
cellular carbohydrate metabolic process GO:0044262 4 0.076
cell morphogenesis involved in differentiation GO:0000904 195 0.076
Fly
response to biotic stimulus GO:0009607 97 0.076
Human
negative regulation of cellular metabolic process GO:0031324 77 0.076
cardiac muscle cell differentiation GO:0055007 30 0.076
negative regulation of cellular biosynthetic process GO:0031327 55 0.076
morphogenesis of embryonic epithelium GO:0016331 30 0.075
regulation of organ growth GO:0046620 3 0.074
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.073
skeletal system morphogenesis GO:0048705 102 0.072
reproductive process GO:0022414 40 0.072
Mouse Fly
transport GO:0006810 220 0.072
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.071
chemosensory behavior GO:0007635 1 0.071
urogenital system development GO:0001655 97 0.070
apoptotic process GO:0006915 116 0.070
Mouse
mesodermal cell fate specification GO:0007501 12 0.070
negative regulation of intracellular protein transport GO:0090317 3 0.070
macromolecule modification GO:0043412 111 0.069
Mouse
immune response GO:0006955 28 0.069
endodermal cell differentiation GO:0035987 19 0.069
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.069
bmp signaling pathway involved in heart development GO:0061312 15 0.068
periodic partitioning GO:0007365 1 0.068
mesoderm development GO:0007498 88 0.068
maintenance of location GO:0051235 4 0.067
regulation of protein import into nucleus GO:0042306 2 0.067
nucleocytoplasmic transport GO:0006913 4 0.066
response to nutrient GO:0007584 3 0.066
otic placode formation GO:0043049 23 0.066
fin regeneration GO:0031101 51 0.066
phosphorus metabolic process GO:0006793 109 0.066
Mouse
pigment metabolic process GO:0042440 12 0.066
stem cell differentiation GO:0048863 117 0.066
rhombomere formation GO:0021594 12 0.065
eye morphogenesis GO:0048592 144 0.065
Zebrafish
connective tissue development GO:0061448 99 0.064
negative regulation of cell death GO:0060548 60 0.064
regulation of phosphorus metabolic process GO:0051174 43 0.064
Mouse
single organism nuclear import GO:1902593 3 0.064
rhombomere morphogenesis GO:0021593 17 0.063
pancreas development GO:0031016 84 0.063
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.063
Zebrafish
mechanoreceptor differentiation GO:0042490 37 0.063
negative regulation of rna biosynthetic process GO:1902679 45 0.063
embryonic hemopoiesis GO:0035162 53 0.062
intracellular signal transduction GO:0035556 85 0.062
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.061
Human Mouse
mesenchymal cell differentiation GO:0048762 87 0.060
regulation of protein transport GO:0051223 3 0.060
segmentation GO:0035282 97 0.060
Human
protein complex assembly GO:0006461 30 0.060
neural nucleus development GO:0048857 15 0.060
Zebrafish
response to xenobiotic stimulus GO:0009410 45 0.060
wound healing GO:0042060 90 0.059
Zebrafish
developmental process involved in reproduction GO:0003006 27 0.059
Mouse Fly
single organismal cell cell adhesion GO:0016337 29 0.059
mesoderm formation GO:0001707 43 0.059
otic vesicle formation GO:0030916 27 0.059
positive regulation of jnk cascade GO:0046330 3 0.058
Mouse
somatic muscle development GO:0007525 4 0.058
negative regulation of rna metabolic process GO:0051253 48 0.058
positive regulation of developmental process GO:0051094 50 0.058
positive regulation of response to stimulus GO:0048584 80 0.057
Mouse
spinal cord development GO:0021510 46 0.057
Zebrafish
regulation of carbohydrate metabolic process GO:0006109 4 0.057
regulation of autophagy GO:0010506 3 0.057
negative regulation of reproductive process GO:2000242 3 0.056
negative regulation of programmed cell death GO:0043069 58 0.056
epithelial cell development GO:0002064 42 0.055
organic acid metabolic process GO:0006082 31 0.055
striated muscle cell differentiation GO:0051146 129 0.055
macroautophagy GO:0016236 1 0.055
neural crest cell differentiation GO:0014033 72 0.054
regulation of response to stress GO:0080134 36 0.054
Mouse
vasculature development GO:0001944 278 0.054
Mouse
neuromast development GO:0048884 46 0.054
synaptic growth at neuromuscular junction GO:0051124 2 0.054
regulation of cell fate specification GO:0042659 20 0.054
multi organism process GO:0051704 134 0.054
Human
epithelial to mesenchymal transition GO:0001837 21 0.054
growth GO:0040007 174 0.054
Zebrafish Fly
olfactory bulb development GO:0021772 4 0.053
exocrine system development GO:0035272 28 0.052
Fly
regulation of establishment of protein localization GO:0070201 4 0.052
regulation of peptidase activity GO:0052547 23 0.052
ectodermal placode development GO:0071696 37 0.052
Zebrafish
nuclear import GO:0051170 3 0.052
inner ear development GO:0048839 126 0.051
activation of mapk activity GO:0000187 3 0.051
negative regulation of oocyte development GO:0060283 2 0.051
regulation of organ morphogenesis GO:2000027 35 0.051
otic vesicle morphogenesis GO:0071600 34 0.050
regulation of response to extracellular stimulus GO:0032104 1 0.050
response to hexose GO:0009746 3 0.049
endocardial cushion formation GO:0003272 2 0.049
response to glucose GO:0009749 3 0.049
hepaticobiliary system development GO:0061008 98 0.049
striated muscle tissue development GO:0014706 110 0.049
multi organism reproductive process GO:0044703 36 0.049
photoreceptor cell differentiation GO:0046530 55 0.049
cell proliferation GO:0008283 80 0.048
Mouse Fly
oocyte development GO:0048599 14 0.048
mesodermal cell differentiation GO:0048333 21 0.048
response to uv GO:0009411 3 0.048
axon extension GO:0048675 45 0.048
Fly
developmental cell growth GO:0048588 52 0.048
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.047
centrosome organization GO:0051297 1 0.047
epithelial cell differentiation GO:0030855 116 0.047
response to decreased oxygen levels GO:0036293 25 0.047
type b pancreatic cell development GO:0003323 4 0.047
endodermal cell fate determination GO:0007493 2 0.046
negative regulation of protein localization to nucleus GO:1900181 2 0.046
embryonic eye morphogenesis GO:0048048 30 0.046
Zebrafish
cilium morphogenesis GO:0060271 85 0.046
Zebrafish
endothelial cell differentiation GO:0045446 20 0.046
negative regulation of catabolic process GO:0009895 3 0.045
otic vesicle development GO:0071599 42 0.045
sensory organ morphogenesis GO:0090596 200 0.045
Zebrafish
oogenesis GO:0048477 14 0.045
regulation of neuron projection regeneration GO:0070570 7 0.045
cell cycle GO:0007049 93 0.045
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.044
olfactory lobe development GO:0021988 4 0.044
regulation of endodermal cell differentiation GO:1903224 15 0.044
positive regulation of epithelial cell differentiation GO:0030858 2 0.044
bone development GO:0060348 14 0.043
floor plate development GO:0033504 15 0.043
embryonic organ development GO:0048568 381 0.043
Zebrafish Mouse
hematopoietic progenitor cell differentiation GO:0002244 23 0.043
negative regulation of cell proliferation GO:0008285 8 0.043
Mouse
endodermal cell fate commitment GO:0001711 18 0.043
developmental maturation GO:0021700 34 0.043
Mouse
lateral line system development GO:0048925 76 0.042
leukocyte activation GO:0045321 12 0.042
Mouse
multicellular organism reproduction GO:0032504 35 0.042
cellular response to oxygen containing compound GO:1901701 20 0.042
regulation of cell size GO:0008361 29 0.042
embryonic skeletal system development GO:0048706 97 0.042
cardiac muscle tissue development GO:0048738 48 0.041
endothelium development GO:0003158 25 0.041
regulation of protein complex assembly GO:0043254 3 0.041
meiotic cell cycle process GO:1903046 3 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.041
endocardium formation GO:0060214 1 0.040
organelle assembly GO:0070925 110 0.040
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.040
single organism reproductive process GO:0044702 40 0.040
Mouse Fly
response to endogenous stimulus GO:0009719 83 0.039
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.039
positive regulation of dna metabolic process GO:0051054 1 0.039
positive regulation of transport GO:0051050 2 0.039
embryonic camera type eye morphogenesis GO:0048596 19 0.039
Zebrafish
mesenchymal cell proliferation GO:0010463 1 0.039
regulation of cell growth GO:0001558 29 0.039
phosphate containing compound metabolic process GO:0006796 108 0.039
Mouse
single organism organelle organization GO:1902589 199 0.038
Zebrafish
protein targeting to nucleus GO:0044744 3 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
stem cell proliferation GO:0072089 4 0.038
positive regulation of cell communication GO:0010647 56 0.038
Mouse
sexual reproduction GO:0019953 36 0.038
ceramide biosynthetic process GO:0046513 1 0.038
positive regulation of catabolic process GO:0009896 4 0.038
nephric duct development GO:0072176 13 0.037
positive regulation of biosynthetic process GO:0009891 68 0.037
Human Mouse
positive regulation of protein metabolic process GO:0051247 23 0.037
Mouse
inner ear morphogenesis GO:0042472 63 0.037
cellular response to starvation GO:0009267 1 0.037
segment polarity determination GO:0007367 1 0.037
signal transduction by phosphorylation GO:0023014 18 0.037
Mouse
small molecule metabolic process GO:0044281 77 0.036
regulation of anatomical structure size GO:0090066 33 0.036
regeneration GO:0031099 91 0.036
Zebrafish
regulation of cell migration GO:0030334 40 0.036
organic substance transport GO:0071702 58 0.036
regulation of epithelial to mesenchymal transition GO:0010717 3 0.036
proteolysis GO:0006508 38 0.036
response to monosaccharide GO:0034284 3 0.036
convergent extension involved in axis elongation GO:0060028 26 0.035
endocardium development GO:0003157 9 0.035
ectodermal placode morphogenesis GO:0071697 32 0.035
Zebrafish
b cell differentiation GO:0030183 1 0.035
negative regulation of cell communication GO:0010648 96 0.035
negative regulation of protein kinase activity GO:0006469 4 0.035
neuron projection extension GO:1990138 45 0.035
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.035
endocrine pancreas development GO:0031018 27 0.034
Zebrafish
regulation of reactive oxygen species metabolic process GO:2000377 2 0.034
system process GO:0003008 185 0.034
negative regulation of intracellular transport GO:0032387 3 0.034
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.034
sphingolipid biosynthetic process GO:0030148 2 0.034
regulation of synapse organization GO:0050807 3 0.034
regulation of immune system process GO:0002682 34 0.034
Fly
multicellular organismal reproductive process GO:0048609 35 0.034
cellular response to oxygen levels GO:0071453 1 0.033
determination of left right asymmetry in diencephalon GO:0035462 4 0.033
regulation of protein phosphorylation GO:0001932 18 0.033
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.033

fzd5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.093
cancer DOID:162 0 0.076
disease of cellular proliferation DOID:14566 0 0.076
disease of metabolism DOID:0014667 0 0.035