Danio rerio

0 known processes

fundc1

FUN14 domain containing 1

(Aliases: zgc:92600)

fundc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.154
regulation of biological quality GO:0065008 263 0.124
neuron differentiation GO:0030182 353 0.123
response to external stimulus GO:0009605 264 0.097
nucleobase containing compound metabolic process GO:0006139 274 0.094
aging GO:0007568 2 0.091
guanosine containing compound catabolic process GO:1901069 2 0.069
cell morphogenesis GO:0000902 289 0.067
phagocytosis GO:0006909 3 0.066
pole plasm assembly GO:0007315 4 0.064
regulation of ion transmembrane transporter activity GO:0032412 2 0.061
generation of neurons GO:0048699 385 0.061
sensory organ development GO:0007423 393 0.060
cellular aromatic compound metabolic process GO:0006725 295 0.059
cytoplasm organization GO:0007028 4 0.059
cell migration GO:0016477 237 0.058
regulation of multicellular organismal process GO:0051239 277 0.058
autophagy GO:0006914 4 0.057
neuron development GO:0048666 262 0.057
oocyte anterior posterior axis specification GO:0007314 4 0.056
nitrogen compound metabolic process GO:0006807 319 0.056
heterocycle biosynthetic process GO:0018130 215 0.055
cell projection organization GO:0030030 284 0.054
guanosine containing compound metabolic process GO:1901068 4 0.053
regulation of metal ion transport GO:0010959 4 0.052
neurotransmitter transport GO:0006836 2 0.052
signal transduction GO:0007165 455 0.051
cellular nitrogen compound metabolic process GO:0034641 290 0.051
protein localization to plasma membrane GO:0072659 1 0.050
positive regulation of transport GO:0051050 2 0.050
maternal determination of anterior posterior axis embryo GO:0008358 4 0.050
cell projection morphogenesis GO:0048858 244 0.048
cellular component morphogenesis GO:0032989 336 0.047
stem cell proliferation GO:0072089 4 0.047
embryo development ending in birth or egg hatching GO:0009792 271 0.046
regulation of membrane potential GO:0042391 23 0.046
circadian sleep wake cycle GO:0042745 2 0.046
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.045
multi organism process GO:0051704 134 0.044
response to carbohydrate GO:0009743 3 0.044
cellular response to nutrient levels GO:0031669 2 0.044
regulation of protein transport GO:0051223 3 0.044
mechanosensory behavior GO:0007638 2 0.044
positive regulation of cellular component biogenesis GO:0044089 3 0.043
actin polymerization or depolymerization GO:0008154 2 0.042
regulation of reproductive process GO:2000241 4 0.042
regulation of transmembrane transporter activity GO:0022898 2 0.042
gtp catabolic process GO:0006184 2 0.042
response to chemical GO:0042221 320 0.041
system process GO:0003008 185 0.040
gtp metabolic process GO:0046039 4 0.040
synaptic growth at neuromuscular junction GO:0051124 2 0.039
gene expression GO:0010467 252 0.039
cell motility GO:0048870 244 0.039
aromatic compound biosynthetic process GO:0019438 217 0.039
cellular response to extracellular stimulus GO:0031668 2 0.037
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.037
cellular response to lipopolysaccharide GO:0071222 3 0.036
stem cell fate commitment GO:0048865 1 0.036
establishment of protein localization to organelle GO:0072594 4 0.036
response to alkaloid GO:0043279 2 0.035
organic cyclic compound metabolic process GO:1901360 301 0.035
single organism localization GO:1902578 225 0.035
ion transport GO:0006811 114 0.035
compound eye development GO:0048749 2 0.035
regulation of autophagy GO:0010506 3 0.034
endosomal transport GO:0016197 2 0.034
cation transmembrane transport GO:0098655 65 0.034
cellular response to starvation GO:0009267 1 0.033
ion transmembrane transport GO:0034220 91 0.033
positive regulation of cell cycle GO:0045787 3 0.032
adult behavior GO:0030534 2 0.032
response to glucose GO:0009749 3 0.032
organelle organization GO:0006996 227 0.032
locomotor rhythm GO:0045475 3 0.032
synaptic vesicle transport GO:0048489 1 0.031
regulation of nucleotide catabolic process GO:0030811 2 0.031
single organism transport GO:0044765 206 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
cellular response to oxygen levels GO:0071453 1 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
regulation of metabolic process GO:0019222 359 0.029
regulation of circadian rhythm GO:0042752 4 0.029
regulation of developmental process GO:0050793 247 0.029
response to monosaccharide GO:0034284 3 0.029
cell morphogenesis involved in differentiation GO:0000904 195 0.029
transmission of nerve impulse GO:0019226 19 0.029
metal ion homeostasis GO:0055065 26 0.029
regulation of carbohydrate metabolic process GO:0006109 4 0.029
regulation of protein complex assembly GO:0043254 3 0.028
cell part morphogenesis GO:0032990 246 0.028
fertilization GO:0009566 3 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
positive regulation of catabolic process GO:0009896 4 0.028
cellular response to external stimulus GO:0071496 2 0.028
rna localization GO:0006403 4 0.028
single organism organelle organization GO:1902589 199 0.028
positive regulation of protein complex assembly GO:0031334 2 0.028
regulation of intracellular protein transport GO:0033157 3 0.027
regulation of cell shape GO:0008360 1 0.027
protein polymerization GO:0051258 4 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
cytoskeleton organization GO:0007010 96 0.027
neuron projection morphogenesis GO:0048812 161 0.027
biosynthetic process GO:0009058 294 0.027
protein import GO:0017038 3 0.027
sleep GO:0030431 1 0.027
synaptic vesicle localization GO:0097479 1 0.026
regulation of synaptic plasticity GO:0048167 1 0.026
ameboidal type cell migration GO:0001667 143 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
regulation of response to stimulus GO:0048583 269 0.026
stem cell division GO:0017145 1 0.026
localization of cell GO:0051674 244 0.026
regulation of cell projection organization GO:0031344 44 0.026
response to hydrogen peroxide GO:0042542 3 0.026
cell substrate adhesion GO:0031589 4 0.025
adherens junction organization GO:0034332 4 0.025
synaptic transmission GO:0007268 35 0.025
transport GO:0006810 220 0.025
regulation of transporter activity GO:0032409 2 0.025
establishment or maintenance of cell polarity GO:0007163 29 0.025
regulation of cytokine production GO:0001817 3 0.025
regulation of gene expression GO:0010468 265 0.025
single fertilization GO:0007338 3 0.025
lipid catabolic process GO:0016042 4 0.025
digestive system development GO:0055123 289 0.024
regulation of signaling GO:0023051 235 0.024
sodium ion transport GO:0006814 24 0.024
establishment of synaptic vesicle localization GO:0097480 1 0.024
peptidyl serine phosphorylation GO:0018105 1 0.024
cellular component biogenesis GO:0044085 178 0.024
response to organic substance GO:0010033 153 0.024
neuron neuron synaptic transmission GO:0007270 1 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
regulation of synapse organization GO:0050807 3 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
positive regulation of cytokine production GO:0001819 2 0.024
anterior posterior pattern specification GO:0009952 152 0.023
cell cycle arrest GO:0007050 1 0.023
sensory perception of chemical stimulus GO:0007606 3 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
tissue remodeling GO:0048771 4 0.023
regulation of neuron differentiation GO:0045664 56 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
atp catabolic process GO:0006200 4 0.023
rna metabolic process GO:0016070 219 0.022
multicellular organism growth GO:0035264 4 0.022
locomotion GO:0040011 313 0.022
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.022
regulation of nervous system development GO:0051960 90 0.022
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.022
lipid storage GO:0019915 1 0.022
regulation of neuronal synaptic plasticity GO:0048168 1 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
organic substance biosynthetic process GO:1901576 289 0.022
actin filament polymerization GO:0030041 2 0.022
regulation of dendrite morphogenesis GO:0048814 3 0.021
regulation of erk1 and erk2 cascade GO:0070372 4 0.021
regulation of cell development GO:0060284 100 0.021
regulation of cell differentiation GO:0045595 142 0.021
single organism metabolic process GO:0044710 217 0.021
response to drug GO:0042493 3 0.021
amine metabolic process GO:0009308 2 0.021
growth GO:0040007 174 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
cellular response to radiation GO:0071478 4 0.021
nucleic acid templated transcription GO:0097659 181 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
proteasomal protein catabolic process GO:0010498 2 0.020
circadian sleep wake cycle process GO:0022410 2 0.020
neuron projection development GO:0031175 180 0.020
negative regulation of biological process GO:0048519 304 0.020
tube morphogenesis GO:0035239 349 0.020
membrane fusion GO:0061025 2 0.020
brain development GO:0007420 293 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
response to stress GO:0006950 263 0.020
regulation of calcium ion transport GO:0051924 2 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
regulation of transcription dna templated GO:0006355 213 0.019
regulation of cellular component organization GO:0051128 86 0.019
epithelial cell development GO:0002064 42 0.019
regulation of photoreceptor cell differentiation GO:0046532 2 0.019
embryonic organ development GO:0048568 381 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
cell death GO:0008219 121 0.019
developmental growth GO:0048589 166 0.019
neuroblast differentiation GO:0014016 1 0.019
circadian sleep wake cycle sleep GO:0050802 1 0.019
rna biosynthetic process GO:0032774 181 0.019
regulation of rna metabolic process GO:0051252 224 0.019
defense response to fungus GO:0050832 2 0.019
cytokinesis GO:0000910 3 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
mitochondrion organization GO:0007005 4 0.019
estrogen metabolic process GO:0008210 2 0.019
negative regulation of synapse assembly GO:0051964 2 0.019
regulation of synapse assembly GO:0051963 3 0.019
gastrulation GO:0007369 208 0.018
sodium ion transmembrane transport GO:0035725 21 0.018
maintenance of location GO:0051235 4 0.018
regulation of cell communication GO:0010646 232 0.018
cation homeostasis GO:0055080 33 0.018
response to hexose GO:0009746 3 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
cellular component assembly GO:0022607 170 0.018
convergent extension GO:0060026 118 0.018
negative regulation of cell communication GO:0010648 96 0.018
transcription dna templated GO:0006351 181 0.018
inorganic ion transmembrane transport GO:0098660 57 0.018
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.018
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.018
homeostatic process GO:0042592 142 0.018
hormone transport GO:0009914 2 0.018
establishment of localization in cell GO:0051649 77 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
intracellular mrna localization GO:0008298 1 0.018
apical junction assembly GO:0043297 1 0.018
digestive tract morphogenesis GO:0048546 231 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
stem cell maintenance GO:0019827 4 0.017
gamete generation GO:0007276 33 0.017
response to external biotic stimulus GO:0043207 97 0.017
regulation of receptor mediated endocytosis GO:0048259 4 0.017
heterocycle metabolic process GO:0046483 290 0.017
skeletal system development GO:0001501 181 0.017
cellular response to decreased oxygen levels GO:0036294 1 0.017
organic acid metabolic process GO:0006082 31 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
regulation of cellular ph GO:0030641 1 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
glucose homeostasis GO:0042593 1 0.017
energy reserve metabolic process GO:0006112 2 0.017
intracellular signal transduction GO:0035556 85 0.017
cellular component movement GO:0006928 335 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
cellular response to hypoxia GO:0071456 1 0.016
regulation of cellular component size GO:0032535 30 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
digestive tract development GO:0048565 265 0.016
post embryonic morphogenesis GO:0009886 4 0.016
cellular protein catabolic process GO:0044257 4 0.016
regulation of binding GO:0051098 3 0.016
cell junction maintenance GO:0034331 2 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
startle response GO:0001964 4 0.016
response to oxidative stress GO:0006979 11 0.016
establishment of protein localization to plasma membrane GO:0090002 1 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
response to biotic stimulus GO:0009607 97 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
establishment of endothelial barrier GO:0061028 3 0.016
cell cell signaling GO:0007267 52 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
cortical actin cytoskeleton organization GO:0030866 1 0.016
chemosensory behavior GO:0007635 1 0.016
regulation of dendrite development GO:0050773 3 0.016
cell substrate junction assembly GO:0007044 2 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
cell fate specification GO:0001708 68 0.015
cellular localization GO:0051641 97 0.015
neuron projection guidance GO:0097485 86 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
medulla oblongata development GO:0021550 4 0.015
regulation of sodium ion transport GO:0002028 2 0.015
cell fate commitment GO:0045165 99 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
regulation of ph GO:0006885 3 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
muscle structure development GO:0061061 196 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
regulation of cell projection assembly GO:0060491 4 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
synaptic vesicle endocytosis GO:0048488 1 0.015
protein localization to nucleus GO:0034504 3 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
response to other organism GO:0051707 97 0.015
nuclear import GO:0051170 3 0.014
regulation of jak stat cascade GO:0046425 3 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
peptidyl serine modification GO:0018209 2 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
regulation of postsynaptic membrane potential GO:0060078 1 0.014
macroautophagy GO:0016236 1 0.014
skeletal system morphogenesis GO:0048705 102 0.014
establishment of localization GO:0051234 244 0.014
nucleic acid metabolic process GO:0090304 244 0.014
regulation of intracellular ph GO:0051453 1 0.014
muscle organ development GO:0007517 101 0.014
central nervous system development GO:0007417 387 0.014
meiotic nuclear division GO:0007126 4 0.014
actin filament based process GO:0030029 64 0.014
immune system process GO:0002376 241 0.014
synaptic transmission cholinergic GO:0007271 4 0.014
wound healing GO:0042060 90 0.014
protein secretion GO:0009306 1 0.014
negative regulation of intracellular protein transport GO:0090317 3 0.014
head development GO:0060322 303 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
cell matrix adhesion GO:0007160 4 0.014
multicellular organismal reproductive process GO:0048609 35 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
photoreceptor cell development GO:0042461 40 0.013
nuclear migration GO:0007097 3 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
smooth muscle contraction GO:0006939 2 0.013
eye development GO:0001654 277 0.013
small molecule catabolic process GO:0044282 3 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
multicellular organismal response to stress GO:0033555 2 0.013
regulation of anatomical structure size GO:0090066 33 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
negative regulation of signaling GO:0023057 96 0.013
taxis GO:0042330 109 0.013
chemical homeostasis GO:0048878 49 0.013
neuroblast proliferation GO:0007405 2 0.013
protein heterooligomerization GO:0051291 1 0.013
response to growth factor GO:0070848 39 0.013
protein import into nucleus GO:0006606 3 0.013
programmed cell death GO:0012501 119 0.013
neuronal action potential GO:0019228 18 0.013
urogenital system development GO:0001655 97 0.013
viral process GO:0016032 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
bone remodeling GO:0046849 2 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.013
response to ph GO:0009268 2 0.013
sexual reproduction GO:0019953 36 0.013
regulation of protein targeting GO:1903533 2 0.012
lipid oxidation GO:0034440 1 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
chordate embryonic development GO:0043009 271 0.012
regulation of molecular function GO:0065009 70 0.012
response to organic cyclic compound GO:0014070 51 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
negative regulation of signal transduction GO:0009968 94 0.012
axonogenesis GO:0007409 152 0.012
response to uv GO:0009411 3 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
calcium ion dependent exocytosis GO:0017156 1 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
regulation of oligodendrocyte differentiation GO:0048713 1 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
protein homooligomerization GO:0051260 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.012
epithelial cell differentiation GO:0030855 116 0.012
protein targeting to nucleus GO:0044744 3 0.012
regulation of cell activation GO:0050865 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of protein polymerization GO:0032271 2 0.012
positive regulation of biological process GO:0048518 253 0.011
germ cell development GO:0007281 22 0.011
regulation of inflammatory response GO:0050727 2 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.011
antimicrobial humoral response GO:0019730 2 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
cellular response to light stimulus GO:0071482 4 0.011
notch signaling pathway GO:0007219 35 0.011
monovalent inorganic cation homeostasis GO:0055067 9 0.011
monoamine transport GO:0015844 1 0.011
embryonic pattern specification GO:0009880 44 0.011
multicellular organismal signaling GO:0035637 22 0.011
actin cytoskeleton organization GO:0030036 63 0.011
regulation of circadian sleep wake cycle GO:0042749 1 0.011
developmental maturation GO:0021700 34 0.011
regulation of dna replication GO:0006275 3 0.011
negative regulation of kinase activity GO:0033673 4 0.011
reproduction GO:0000003 40 0.011
positive regulation of cell activation GO:0050867 1 0.011
neuroblast fate commitment GO:0014017 1 0.011
regulation of cell size GO:0008361 29 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
regionalization GO:0003002 274 0.011
negative regulation of developmental process GO:0051093 65 0.011
hatching GO:0035188 4 0.011
cellular amine metabolic process GO:0044106 2 0.011
sensory organ morphogenesis GO:0090596 200 0.011
negative regulation of cellular process GO:0048523 283 0.011
single organism membrane fusion GO:0044801 2 0.011
single organism cellular localization GO:1902580 46 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
protein complex subunit organization GO:0071822 46 0.011
exocytosis GO:0006887 1 0.011
cation transport GO:0006812 81 0.010
organelle fusion GO:0048284 3 0.010
negative regulation of map kinase activity GO:0043407 2 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
response to radiation GO:0009314 51 0.010
action potential GO:0001508 19 0.010
membrane repolarization GO:0086009 2 0.010
response to fungus GO:0009620 25 0.010
oxidation reduction process GO:0055114 41 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
nuclear export GO:0051168 1 0.010
camera type eye development GO:0043010 222 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
positive regulation of metabolic process GO:0009893 108 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
protein targeting to membrane GO:0006612 1 0.010
cellular ion homeostasis GO:0006873 17 0.010
regulation of glial cell differentiation GO:0045685 4 0.010
multi organism cellular process GO:0044764 2 0.010
macromolecule localization GO:0033036 54 0.010
ion homeostasis GO:0050801 41 0.010
negative regulation of catabolic process GO:0009895 3 0.010
organelle assembly GO:0070925 110 0.010
macromolecular complex disassembly GO:0032984 1 0.010

fundc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.031
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013