Danio rerio

0 known processes

twist3

twist3

(Aliases: twist2,twist-2,hm:zeh0190)

twist3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.990
Zebrafish
chordate embryonic development GO:0043009 271 0.986
Zebrafish
skeletal system development GO:0001501 181 0.985
Zebrafish
biosynthetic process GO:0009058 294 0.979
Zebrafish Worm Fly
embryonic organ morphogenesis GO:0048562 274 0.974
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.967
Zebrafish Worm Fly
embryonic skeletal system development GO:0048706 97 0.962
Zebrafish
appendage development GO:0048736 80 0.961
Zebrafish
embryonic organ development GO:0048568 381 0.957
Zebrafish
tube morphogenesis GO:0035239 349 0.952
Zebrafish Worm Fly
sensory organ morphogenesis GO:0090596 200 0.941
Zebrafish
heart jogging GO:0003146 40 0.923
cellular biosynthetic process GO:0044249 286 0.921
Zebrafish Worm Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.914
Zebrafish Worm Fly
organic substance biosynthetic process GO:1901576 289 0.914
Zebrafish Worm Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.911
Zebrafish
rna biosynthetic process GO:0032774 181 0.908
Zebrafish Worm Fly
specification of symmetry GO:0009799 204 0.907
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.903
Zebrafish Worm Fly
regionalization GO:0003002 274 0.892
heterocycle biosynthetic process GO:0018130 215 0.887
Zebrafish Worm Fly
blood vessel morphogenesis GO:0048514 216 0.879
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.866
Zebrafish Worm Fly
embryonic limb morphogenesis GO:0030326 2 0.844
enzyme linked receptor protein signaling pathway GO:0007167 106 0.837
appendage morphogenesis GO:0035107 56 0.834
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.829
Worm Fly
regulation of transcription dna templated GO:0006355 213 0.828
Zebrafish Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.824
Zebrafish Worm Fly
mesoderm development GO:0007498 88 0.818
Zebrafish Worm Fly
stem cell proliferation GO:0072089 4 0.815
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.802
positive regulation of cellular process GO:0048522 201 0.802
Zebrafish Worm Fly
nucleic acid metabolic process GO:0090304 244 0.797
Zebrafish Worm Fly
embryonic camera type eye formation GO:0060900 10 0.795
nucleic acid templated transcription GO:0097659 181 0.794
Zebrafish Worm Fly
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.787
macromolecule biosynthetic process GO:0009059 227 0.784
Zebrafish Worm Fly
regulation of response to stimulus GO:0048583 269 0.781
cellular aromatic compound metabolic process GO:0006725 295 0.774
Zebrafish Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.774
Zebrafish Worm Fly
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.772
determination of bilateral symmetry GO:0009855 204 0.749
Zebrafish
muscle structure development GO:0061061 196 0.743
Fly
dorsal ventral pattern formation GO:0009953 125 0.735
transcription from rna polymerase ii promoter GO:0006366 80 0.726
Worm Fly
negative regulation of cellular process GO:0048523 283 0.723
Zebrafish
mesenchyme development GO:0060485 127 0.719
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.705
cellular macromolecule biosynthetic process GO:0034645 224 0.690
Zebrafish Worm Fly
regulation of developmental process GO:0050793 247 0.683
Zebrafish Fly
gene expression GO:0010467 252 0.683
Zebrafish Worm Fly
ear development GO:0043583 127 0.681
Zebrafish
response to stress GO:0006950 263 0.680
Zebrafish
positive regulation of biological process GO:0048518 253 0.679
Zebrafish Worm Fly
regulation of cell differentiation GO:0045595 142 0.668
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.663
Zebrafish Worm Fly
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.641
striated muscle cell differentiation GO:0051146 129 0.641
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.639
Zebrafish Worm Fly
developmental growth GO:0048589 166 0.626
cellular nitrogen compound metabolic process GO:0034641 290 0.625
Zebrafish Worm Fly
regulation of biosynthetic process GO:0009889 250 0.622
Zebrafish Worm Fly
embryonic heart tube morphogenesis GO:0003143 108 0.619
Zebrafish
regulation of chondrocyte differentiation GO:0032330 1 0.610
connective tissue development GO:0061448 99 0.608
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.608
regulation of rna biosynthetic process GO:2001141 213 0.604
Zebrafish Worm Fly
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.603
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.591
Zebrafish Worm Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.580
skeletal system morphogenesis GO:0048705 102 0.579
Zebrafish
regulation of signaling GO:0023051 235 0.576
determination of heart left right asymmetry GO:0061371 117 0.568
regulation of signal transduction GO:0009966 225 0.567
locus ceruleus development GO:0021703 3 0.566
fin development GO:0033333 77 0.561
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.560
Zebrafish Worm Fly
ear morphogenesis GO:0042471 64 0.558
negative regulation of gene expression GO:0010629 65 0.555
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.552
Zebrafish
blood vessel development GO:0001568 246 0.552
Zebrafish
optic placode formation involved in camera type eye formation GO:0046619 3 0.550
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.546
Zebrafish Worm Fly
mesoderm formation GO:0001707 43 0.542
Zebrafish Worm Fly
hair cell differentiation GO:0035315 32 0.535
Zebrafish
fin regeneration GO:0031101 51 0.533
vasculature development GO:0001944 278 0.533
Zebrafish
otic vesicle morphogenesis GO:0071600 34 0.528
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.520
mesenchymal cell proliferation GO:0010463 1 0.513
negative regulation of nucleic acid templated transcription GO:1903507 45 0.504
optic placode formation GO:0001743 4 0.502
nitrogen compound metabolic process GO:0006807 319 0.502
Zebrafish Worm Fly
negative regulation of rna metabolic process GO:0051253 48 0.498
muscle tissue development GO:0060537 110 0.497
Fly
determination of left right symmetry GO:0007368 179 0.492
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.487
Zebrafish
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.486
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.479
embryonic heart tube development GO:0035050 133 0.479
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.477
Zebrafish Worm Fly
regulation of cellular biosynthetic process GO:0031326 245 0.477
Zebrafish Worm Fly
response to wounding GO:0009611 116 0.477
Zebrafish
rna metabolic process GO:0016070 219 0.474
Zebrafish Worm Fly
inner ear morphogenesis GO:0042472 63 0.471
heart looping GO:0001947 94 0.471
adenohypophysis development GO:0021984 15 0.469
negative regulation of cell differentiation GO:0045596 46 0.467
Zebrafish
signal transduction GO:0007165 455 0.466
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.466
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.462
hard palate development GO:0060022 4 0.461
positive regulation of epithelial cell proliferation GO:0050679 1 0.453
bmp signaling pathway involved in heart jogging GO:0003303 14 0.452
eye morphogenesis GO:0048592 144 0.452
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.448
Zebrafish Worm Fly
positive regulation of transcription dna templated GO:0045893 57 0.448
Zebrafish Worm Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.447
Zebrafish Worm Fly
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.447
inner ear development GO:0048839 126 0.446
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.443
Zebrafish Worm Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.440
somitogenesis GO:0001756 87 0.437
transcription dna templated GO:0006351 181 0.435
Zebrafish Worm Fly
skeletal muscle tissue development GO:0007519 67 0.434
regulation of cellular metabolic process GO:0031323 320 0.434
Zebrafish Worm Fly
anterior posterior pattern specification GO:0009952 152 0.432
specification of organ identity GO:0010092 2 0.431
otic placode formation GO:0043049 23 0.430
determination of dorsal ventral asymmetry GO:0048262 34 0.427
cell surface receptor signaling pathway GO:0007166 325 0.426
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.424
regeneration GO:0031099 91 0.423
Zebrafish
negative regulation of rna biosynthetic process GO:1902679 45 0.420
regulation of primary metabolic process GO:0080090 311 0.420
Zebrafish Worm Fly
otic vesicle development GO:0071599 42 0.408
regulation of mesenchymal cell proliferation GO:0010464 1 0.404
stem cell development GO:0048864 82 0.403
generation of neurons GO:0048699 385 0.401
Zebrafish
forebrain development GO:0030900 96 0.396
Zebrafish
cell projection organization GO:0030030 284 0.391
Zebrafish
ameboidal type cell migration GO:0001667 143 0.390
olfactory bulb development GO:0021772 4 0.388
Zebrafish
growth GO:0040007 174 0.382
cell motility GO:0048870 244 0.380
formation of primary germ layer GO:0001704 62 0.374
Zebrafish Worm Fly
pectoral fin development GO:0033339 50 0.372
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.371
regulation of multicellular organismal development GO:2000026 223 0.369
Zebrafish Fly
cartilage development GO:0051216 96 0.363
regulation of nitrogen compound metabolic process GO:0051171 251 0.362
Zebrafish Worm Fly
chemotaxis GO:0006935 104 0.360
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.358
regulation of gene expression GO:0010468 265 0.355
Zebrafish Worm Fly
cell fate specification GO:0001708 68 0.351
Worm
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.351
nephron epithelium morphogenesis GO:0072088 1 0.349
mesenchymal cell differentiation GO:0048762 87 0.349
negative regulation of synapse assembly GO:0051964 2 0.347
nephron morphogenesis GO:0072028 2 0.347
negative regulation of transcription dna templated GO:0045892 45 0.346
head development GO:0060322 303 0.346
Zebrafish
tissue regeneration GO:0042246 74 0.342
cellular component movement GO:0006928 335 0.335
striated muscle tissue development GO:0014706 110 0.335
Fly
regulation of cell communication GO:0010646 232 0.333
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.332
cellular component morphogenesis GO:0032989 336 0.330
bmp signaling pathway involved in heart development GO:0061312 15 0.326
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.324
cell migration GO:0016477 237 0.315
urogenital system development GO:0001655 97 0.314
Fly
neuron differentiation GO:0030182 353 0.308
Zebrafish
mesenchymal cell development GO:0014031 78 0.307
negative regulation of developmental process GO:0051093 65 0.305
Zebrafish
mesoderm morphogenesis GO:0048332 51 0.300
Zebrafish Worm Fly
positive regulation of gene expression GO:0010628 71 0.297
Zebrafish Worm Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.296
Zebrafish Worm Fly
negative regulation of axon guidance GO:1902668 1 0.292
neural nucleus development GO:0048857 15 0.287
behavior GO:0007610 74 0.286
Zebrafish Worm
outflow tract morphogenesis GO:0003151 1 0.282
positive regulation of cell communication GO:0010647 56 0.282
fin morphogenesis GO:0033334 53 0.282
Zebrafish
response to growth factor GO:0070848 39 0.278
cell migration involved in gastrulation GO:0042074 79 0.275
locomotion GO:0040011 313 0.271
negative regulation of cell communication GO:0010648 96 0.268
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.267
Zebrafish Worm Fly
heterocycle metabolic process GO:0046483 290 0.266
Zebrafish Worm Fly
embryonic skeletal joint development GO:0072498 3 0.261
negative regulation of signaling GO:0023057 96 0.255
artery morphogenesis GO:0048844 14 0.254
Zebrafish
regulation of muscle tissue development GO:1901861 6 0.253
Fly
nephron tubule morphogenesis GO:0072078 1 0.253
mesodermal cell fate commitment GO:0001710 14 0.251
Worm Fly
bmp signaling pathway GO:0030509 52 0.246
convergent extension involved in gastrulation GO:0060027 71 0.245
positive regulation of muscle organ development GO:0048636 1 0.241
negative regulation of signal transduction GO:0009968 94 0.240
pons development GO:0021548 11 0.239
morphogenesis of an epithelium GO:0002009 333 0.236
Zebrafish Fly
gland morphogenesis GO:0022612 13 0.236
Fly
regulation of cellular response to growth factor stimulus GO:0090287 35 0.234
regulation of reproductive process GO:2000241 4 0.233
stem cell maintenance GO:0019827 4 0.230
regulation of muscle organ development GO:0048634 9 0.229
Fly
cell proliferation GO:0008283 80 0.226
taxis GO:0042330 109 0.225
regulation of multicellular organismal process GO:0051239 277 0.225
Zebrafish Fly
negative regulation of multicellular organismal process GO:0051241 69 0.222
Zebrafish
cell growth GO:0016049 57 0.221
reproductive process GO:0022414 40 0.218
Worm
gland development GO:0048732 143 0.216
Zebrafish Fly
neuron fate specification GO:0048665 20 0.215
cell morphogenesis involved in differentiation GO:0000904 195 0.214
regulation of axon guidance GO:1902667 8 0.213
activin receptor signaling pathway GO:0032924 8 0.212
positive regulation of metabolic process GO:0009893 108 0.211
Zebrafish Worm Fly
heart development GO:0007507 313 0.211
Zebrafish
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.209
regulation of metabolic process GO:0019222 359 0.208
Zebrafish Worm Fly
myeloid cell differentiation GO:0030099 86 0.208
Zebrafish
axon guidance GO:0007411 86 0.204
muscle cell differentiation GO:0042692 139 0.204
Fly
immune system process GO:0002376 241 0.203
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.202
gastrulation GO:0007369 208 0.199
Zebrafish Worm Fly
cell cell signaling involved in cell fate commitment GO:0045168 12 0.198
regulation of cell development GO:0060284 100 0.197
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.197
regulation of cell proliferation GO:0042127 37 0.196
otic vesicle formation GO:0030916 27 0.195
hemopoiesis GO:0030097 183 0.195
Zebrafish
pituitary gland development GO:0021983 16 0.194
cell fate commitment GO:0045165 99 0.194
Zebrafish Worm Fly
muscle organ development GO:0007517 101 0.190
Fly
camera type eye development GO:0043010 222 0.185
Zebrafish
embryonic camera type eye development GO:0031076 29 0.182
diencephalon development GO:0021536 58 0.178
post anal tail morphogenesis GO:0036342 19 0.178
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.174
canonical wnt signaling pathway GO:0060070 48 0.173
negative regulation of protein phosphorylation GO:0001933 4 0.170
renal tubule morphogenesis GO:0061333 1 0.169
Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.169
Fly
hindbrain morphogenesis GO:0021575 22 0.165
Zebrafish
ectodermal placode formation GO:0060788 26 0.165
regulation of synapse assembly GO:0051963 3 0.164
positive regulation of signal transduction GO:0009967 56 0.163
pericardium development GO:0060039 1 0.162
regulation of stem cell proliferation GO:0072091 2 0.161
retinal ganglion cell axon guidance GO:0031290 35 0.160
craniofacial suture morphogenesis GO:0097094 2 0.160
anterior posterior axon guidance GO:0033564 5 0.160
regulation of nervous system development GO:0051960 90 0.159
Zebrafish
spemann organizer formation GO:0060061 10 0.159
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.159
neuron projection extension GO:1990138 45 0.157
embryonic skeletal joint morphogenesis GO:0060272 3 0.157
chondrocyte differentiation GO:0002062 7 0.156
regulation of anterior head development GO:2000742 2 0.155
positive regulation of cellular metabolic process GO:0031325 94 0.154
Zebrafish Worm Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.152
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.151
digestive tract morphogenesis GO:0048546 231 0.151
Zebrafish Worm Fly
cellular response to growth factor stimulus GO:0071363 39 0.150
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.150
positive regulation of biosynthetic process GO:0009891 68 0.149
Zebrafish Worm Fly
protein localization to nucleus GO:0034504 3 0.149
cell part morphogenesis GO:0032990 246 0.149
cellular response to organic substance GO:0071310 105 0.145
response to external stimulus GO:0009605 264 0.144
cranial suture morphogenesis GO:0060363 1 0.139
odontogenesis of dentin containing tooth GO:0042475 1 0.138
embryonic camera type eye morphogenesis GO:0048596 19 0.137
medial fin development GO:0033338 16 0.137
embryonic digestive tract development GO:0048566 4 0.136
negative regulation of cell fate commitment GO:0010454 13 0.135
cell morphogenesis GO:0000902 289 0.135
cellular response to external stimulus GO:0071496 2 0.135
regulation of cell death GO:0010941 103 0.134
spinal cord anterior posterior patterning GO:0021512 1 0.134
positive regulation of rna metabolic process GO:0051254 59 0.134
Zebrafish Worm Fly
camera type eye morphogenesis GO:0048593 108 0.134
Zebrafish
response to chemical GO:0042221 320 0.133
regulation of cartilage development GO:0061035 7 0.132
fourth ventricle development GO:0021592 8 0.129
striated muscle cell development GO:0055002 108 0.128
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.127
Zebrafish Worm Fly
limb morphogenesis GO:0035108 7 0.125
immune system development GO:0002520 191 0.124
Zebrafish
hepatocyte proliferation GO:0072574 2 0.124
otolith development GO:0048840 32 0.123
Zebrafish
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.123
death GO:0016265 121 0.122
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.121
regulation of synapse organization GO:0050807 3 0.120
dorsal convergence GO:0060030 14 0.120
regulation of endodermal cell fate specification GO:0042663 15 0.120
positive regulation of signaling GO:0023056 56 0.118
ossification GO:0001503 23 0.118
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.117
negative regulation of neurogenesis GO:0050768 20 0.117
Zebrafish
protein import GO:0017038 3 0.117
gall bladder development GO:0061010 1 0.116
epithelium regeneration GO:1990399 14 0.116
determination of ventral identity GO:0048264 21 0.115
regulation of neurogenesis GO:0050767 87 0.115
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.113
protein metabolic process GO:0019538 183 0.113
medial fin morphogenesis GO:0035141 14 0.113
anterior head development GO:0097065 2 0.112
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.112
developmental induction GO:0031128 10 0.111
endocrine system development GO:0035270 65 0.110
Zebrafish
regulation of cell fate commitment GO:0010453 22 0.108
negative regulation of developmental growth GO:0048640 9 0.107
thrombocyte differentiation GO:0002574 4 0.107
semicircular canal formation GO:0060876 4 0.107
negative regulation of biological process GO:0048519 304 0.107
Zebrafish Fly
regulation of stem cell differentiation GO:2000736 4 0.106
negative regulation of cell fate specification GO:0009996 11 0.105
larval development GO:0002164 2 0.104
midbrain hindbrain boundary development GO:0030917 23 0.103
ventricular system development GO:0021591 12 0.103
regulation of bmp signaling pathway GO:0030510 39 0.103
negative regulation of biosynthetic process GO:0009890 55 0.102
wound healing GO:0042060 90 0.102
epithelial to mesenchymal transition GO:0001837 21 0.101
forebrain regionalization GO:0021871 4 0.100
positive regulation of multicellular organismal process GO:0051240 52 0.099
Zebrafish
regulation of programmed cell death GO:0043067 101 0.099
regulation of developmental growth GO:0048638 38 0.099
oocyte maturation GO:0001556 4 0.099
regulation of embryonic development GO:0045995 47 0.099
embryonic digestive tract morphogenesis GO:0048557 3 0.096
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.096
Worm Fly
regulation of organ growth GO:0046620 3 0.096
regulation of cell fate specification GO:0042659 20 0.095
convergent extension GO:0060026 118 0.093
positive regulation of cytokine production GO:0001819 2 0.092
regulation of epithelial to mesenchymal transition GO:0010717 3 0.092
multi organism process GO:0051704 134 0.092
Worm
antimicrobial humoral response GO:0019730 2 0.092
kidney epithelium development GO:0072073 23 0.091
positive regulation of response to stimulus GO:0048584 80 0.090
regulation of striated muscle tissue development GO:0016202 6 0.090
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.089
neuron fate commitment GO:0048663 26 0.088
Zebrafish
regulation of organ morphogenesis GO:2000027 35 0.088
regulation of protein localization to nucleus GO:1900180 2 0.088
mechanoreceptor differentiation GO:0042490 37 0.087
Zebrafish
response to fibroblast growth factor GO:0071774 22 0.087
regulation of cell morphogenesis GO:0022604 42 0.086
regulation of locomotion GO:0040012 55 0.086
central nervous system development GO:0007417 387 0.086
Zebrafish
single organism metabolic process GO:0044710 217 0.085
ectodermal placode development GO:0071696 37 0.084
Zebrafish
regulation of cell growth GO:0001558 29 0.084
cell projection morphogenesis GO:0048858 244 0.081
olfactory lobe development GO:0021988 4 0.081
Zebrafish
neural tube development GO:0021915 62 0.081
retina morphogenesis in camera type eye GO:0060042 79 0.080
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.080
Zebrafish Worm Fly
notochord development GO:0030903 54 0.080
cilium morphogenesis GO:0060271 85 0.079
hepatic duct development GO:0061011 2 0.079
regulation of smoothened signaling pathway GO:0008589 18 0.079
embryonic eye morphogenesis GO:0048048 30 0.078
inner ear receptor cell fate commitment GO:0060120 4 0.077
Zebrafish
regulation of oocyte development GO:0060281 3 0.076
response to organic substance GO:0010033 153 0.076
axonogenesis GO:0007409 152 0.076
regulation of axon extension GO:0030516 24 0.075
neural crest cell development GO:0014032 62 0.075
gliogenesis GO:0042063 45 0.075
myotube differentiation GO:0014902 45 0.075
inner ear receptor cell differentiation GO:0060113 29 0.074
Zebrafish
bone morphogenesis GO:0060349 11 0.074
cellular protein modification process GO:0006464 100 0.074
somite development GO:0061053 96 0.073
chondrocyte development GO:0002063 4 0.073
eye development GO:0001654 277 0.073
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.073
Fly
homeostatic process GO:0042592 142 0.072
Zebrafish
regulation of cellular component organization GO:0051128 86 0.071
negative regulation of response to stimulus GO:0048585 104 0.071
sensory system development GO:0048880 76 0.071
Zebrafish
axon extension GO:0048675 45 0.071
cranial nerve development GO:0021545 42 0.071
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.071
negative regulation of cell projection organization GO:0031345 9 0.070
regulation of growth GO:0040008 42 0.070
embryonic pattern specification GO:0009880 44 0.070
pharyngeal system development GO:0060037 18 0.070
Zebrafish
kidney development GO:0001822 92 0.070
morphogenesis of a branching epithelium GO:0061138 16 0.070
negative regulation of cell development GO:0010721 26 0.070
Zebrafish
specification of organ position GO:0010159 3 0.070
habenula development GO:0021986 9 0.069
negative regulation of mitosis GO:0045839 3 0.068
epithelial tube morphogenesis GO:0060562 148 0.068
Zebrafish Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.068
Zebrafish Worm Fly
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.067
primary neural tube formation GO:0014020 1 0.067
regulation of biological quality GO:0065008 263 0.067
Zebrafish
single organism reproductive process GO:0044702 40 0.067
osteoblast differentiation GO:0001649 5 0.066
mediolateral intercalation GO:0060031 3 0.066
regulation of apoptotic process GO:0042981 98 0.065
cardiogenic plate morphogenesis GO:0003142 1 0.065
Zebrafish
regulation of canonical wnt signaling pathway GO:0060828 34 0.064
renal system development GO:0072001 94 0.063
Fly
tube closure GO:0060606 1 0.063
regulation of cell migration GO:0030334 40 0.063
negative regulation of endodermal cell differentiation GO:1903225 8 0.063
neuron projection guidance GO:0097485 86 0.062
positive regulation of cell differentiation GO:0045597 30 0.062
Zebrafish
neural crest cell differentiation GO:0014033 72 0.062
negative regulation of striated muscle tissue development GO:0045843 2 0.062
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.060
rhombomere 5 development GO:0021571 4 0.059
negative regulation of muscle organ development GO:0048635 5 0.058
mesodermal cell differentiation GO:0048333 21 0.058
Zebrafish Worm Fly
developmental process involved in reproduction GO:0003006 27 0.058
regulation of epithelial cell proliferation GO:0050678 3 0.058
epithalamus development GO:0021538 10 0.057
anatomical structure homeostasis GO:0060249 36 0.056
regulation of production of molecular mediator of immune response GO:0002700 1 0.056
fat soluble vitamin metabolic process GO:0006775 4 0.056
retina development in camera type eye GO:0060041 146 0.055
Zebrafish
positive regulation of developmental process GO:0051094 50 0.055
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.054
cardiac muscle cell differentiation GO:0055007 30 0.054
peptidyl threonine phosphorylation GO:0018107 1 0.053
negative regulation of gastrulation GO:2000542 11 0.053
positive regulation of stem cell proliferation GO:2000648 1 0.052
neural plate pattern specification GO:0060896 12 0.052
positive regulation of cell development GO:0010720 25 0.050
Zebrafish
stem cell differentiation GO:0048863 117 0.049
Zebrafish
morphogenesis of embryonic epithelium GO:0016331 30 0.049
Zebrafish
central nervous system neuron differentiation GO:0021953 74 0.049
Zebrafish
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.048
type b pancreatic cell development GO:0003323 4 0.048
apoptotic process GO:0006915 116 0.048
odontogenesis GO:0042476 9 0.047
skeletal muscle organ development GO:0060538 78 0.047
heart contraction GO:0060047 71 0.047
Zebrafish
negative regulation of endodermal cell fate specification GO:0042664 8 0.047
female sex differentiation GO:0046660 4 0.046
carboxylic acid metabolic process GO:0019752 22 0.046
neural precursor cell proliferation GO:0061351 20 0.046
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
regulation of axon extension involved in axon guidance GO:0048841 6 0.045
vestibular receptor cell development GO:0060118 3 0.045
cell proliferation in hindbrain GO:0021534 4 0.045
regulation of gastrulation GO:0010470 24 0.045
angiogenesis GO:0001525 158 0.045
Zebrafish
negative regulation of kinase activity GO:0033673 4 0.044
regulation of multicellular organism growth GO:0040014 4 0.044
negative regulation of cell death GO:0060548 60 0.044
organ formation GO:0048645 17 0.043
wnt signaling pathway GO:0016055 80 0.043
negative regulation of protein kinase activity GO:0006469 4 0.043
pronephros development GO:0048793 69 0.042
regulation of transcription involved in cell fate commitment GO:0060850 1 0.042
cellular amine metabolic process GO:0044106 2 0.042
cellular response to endogenous stimulus GO:0071495 68 0.040
hepaticobiliary system development GO:0061008 98 0.040
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.040
limb bud formation GO:0060174 2 0.040
endoderm development GO:0007492 49 0.040
sequestering of metal ion GO:0051238 3 0.039
axis elongation GO:0003401 31 0.039
neuron development GO:0048666 262 0.039
Zebrafish
stem cell division GO:0017145 1 0.039
pharyngeal muscle development GO:0043282 4 0.038
positive regulation of smoothened signaling pathway GO:0045880 5 0.038
peptidyl serine phosphorylation GO:0018105 1 0.038
peptidyl serine modification GO:0018209 2 0.038
brain morphogenesis GO:0048854 18 0.037
axonal defasciculation GO:0007414 2 0.037
developmental cell growth GO:0048588 52 0.037
regulation of cell projection organization GO:0031344 44 0.036
localization of cell GO:0051674 244 0.036
cellular amino acid metabolic process GO:0006520 7 0.036
positive regulation of reproductive process GO:2000243 2 0.035

twist3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.112
musculoskeletal system disease DOID:17 0 0.084
bone development disease DOID:0080006 0 0.057
bone disease DOID:0080001 0 0.057
connective tissue disease DOID:65 0 0.057
cardiovascular system disease DOID:1287 0 0.040
immune system disease DOID:2914 0 0.038