Danio rerio

30 known processes

ddt

D-dopachrome tautomerase

(Aliases: wu:fb49f11,zgc:86714)

ddt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inner ear development GO:0048839 126 0.218
neuron differentiation GO:0030182 353 0.163
positive regulation of map kinase activity GO:0043406 3 0.150
aging GO:0007568 2 0.146
negative regulation of biological process GO:0048519 304 0.126
positive regulation of transport GO:0051050 2 0.104
single organism metabolic process GO:0044710 217 0.090
regulation of protein transport GO:0051223 3 0.085
response to chemical GO:0042221 320 0.084
negative regulation of cellular process GO:0048523 283 0.082
morphogenesis of an epithelium GO:0002009 333 0.081
nitrogen compound metabolic process GO:0006807 319 0.078
immune system process GO:0002376 241 0.074
cell morphogenesis GO:0000902 289 0.068
organic substance biosynthetic process GO:1901576 289 0.067
neuron projection development GO:0031175 180 0.066
cell death GO:0008219 121 0.063
ear development GO:0043583 127 0.062
digestive tract development GO:0048565 265 0.061
organic acid metabolic process GO:0006082 31 0.061
establishment of localization GO:0051234 244 0.059
oxoacid metabolic process GO:0043436 31 0.059
cellular component morphogenesis GO:0032989 336 0.058
neuron development GO:0048666 262 0.058
organonitrogen compound metabolic process GO:1901564 74 0.056
cell projection organization GO:0030030 284 0.055
biosynthetic process GO:0009058 294 0.055
monocyte differentiation GO:0030224 2 0.055
cell part morphogenesis GO:0032990 246 0.054
small molecule metabolic process GO:0044281 77 0.053
protein homooligomerization GO:0051260 3 0.052
regulation of muscle contraction GO:0006937 3 0.050
adult behavior GO:0030534 2 0.048
neuron projection morphogenesis GO:0048812 161 0.045
regulation of multicellular organism growth GO:0040014 4 0.044
small molecule catabolic process GO:0044282 3 0.044
organonitrogen compound biosynthetic process GO:1901566 47 0.044
ion transport GO:0006811 114 0.044
regulation of signal transduction GO:0009966 225 0.043
cellular amine metabolic process GO:0044106 2 0.043
cellular component movement GO:0006928 335 0.043
apoptotic process GO:0006915 116 0.042
embryonic organ development GO:0048568 381 0.042
signal transduction GO:0007165 455 0.042
ribonucleoside monophosphate catabolic process GO:0009158 4 0.042
regulation of cell communication GO:0010646 232 0.042
single organism biosynthetic process GO:0044711 71 0.041
neurotransmitter transport GO:0006836 2 0.041
head development GO:0060322 303 0.040
protein secretion GO:0009306 1 0.039
regulation of transmembrane transporter activity GO:0022898 2 0.038
single organism nuclear import GO:1902593 3 0.038
cell morphogenesis involved in differentiation GO:0000904 195 0.038
amine metabolic process GO:0009308 2 0.038
lipid metabolic process GO:0006629 52 0.038
larval development GO:0002164 2 0.038
aromatic compound biosynthetic process GO:0019438 217 0.037
tetrapyrrole metabolic process GO:0033013 10 0.037
atp catabolic process GO:0006200 4 0.037
cellular transition metal ion homeostasis GO:0046916 3 0.036
regulation of metal ion transport GO:0010959 4 0.036
response to nutrient GO:0007584 3 0.035
cellular biosynthetic process GO:0044249 286 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.034
cell surface receptor signaling pathway GO:0007166 325 0.034
regulation of ion transmembrane transporter activity GO:0032412 2 0.034
response to corticosteroid GO:0031960 1 0.033
cofactor metabolic process GO:0051186 15 0.033
hydrogen peroxide metabolic process GO:0042743 2 0.033
regulation of blood pressure GO:0008217 1 0.033
alcohol biosynthetic process GO:0046165 2 0.032
cell projection morphogenesis GO:0048858 244 0.032
transmembrane transport GO:0055085 120 0.032
cellular ketone metabolic process GO:0042180 11 0.032
regulation of primary metabolic process GO:0080090 311 0.032
cytoskeleton organization GO:0007010 96 0.031
regulation of systemic arterial blood pressure GO:0003073 1 0.031
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
regulation of metabolic process GO:0019222 359 0.031
establishment of localization in cell GO:0051649 77 0.031
cellular localization GO:0051641 97 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
single organism localization GO:1902578 225 0.030
response to glucocorticoid GO:0051384 1 0.029
camera type eye development GO:0043010 222 0.029
single organism transport GO:0044765 206 0.029
cellular amino acid biosynthetic process GO:0008652 2 0.029
heme metabolic process GO:0042168 9 0.029
ion transmembrane transport GO:0034220 91 0.028
digestive tract morphogenesis GO:0048546 231 0.028
microtubule organizing center organization GO:0031023 1 0.027
actin filament based movement GO:0030048 1 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
organelle localization GO:0051640 49 0.026
actin polymerization or depolymerization GO:0008154 2 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
centrosome organization GO:0051297 1 0.026
locomotion GO:0040011 313 0.025
regulation of striated muscle contraction GO:0006942 2 0.025
regulation of apoptotic process GO:0042981 98 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
organelle organization GO:0006996 227 0.025
localization of cell GO:0051674 244 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
nucleoside monophosphate catabolic process GO:0009125 4 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
regulation of actin filament based movement GO:1903115 1 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
myeloid leukocyte differentiation GO:0002573 15 0.024
homeostatic process GO:0042592 142 0.024
alcohol metabolic process GO:0006066 11 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
regulation of multicellular organismal process GO:0051239 277 0.023
protein import into nucleus GO:0006606 3 0.023
neurotransmitter secretion GO:0007269 2 0.023
tube morphogenesis GO:0035239 349 0.023
heart process GO:0003015 71 0.023
hormone transport GO:0009914 2 0.023
regulation of neuron differentiation GO:0045664 56 0.023
pyruvate metabolic process GO:0006090 1 0.022
digestive system development GO:0055123 289 0.022
neuron projection guidance GO:0097485 86 0.022
response to stress GO:0006950 263 0.022
retinoid metabolic process GO:0001523 15 0.022
regulation of cytokine production GO:0001817 3 0.022
regulation of autophagy GO:0010506 3 0.021
positive regulation of secretion GO:0051047 1 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
regulation of response to stimulus GO:0048583 269 0.021
sensory organ development GO:0007423 393 0.021
regulation of signaling GO:0023051 235 0.020
programmed cell death GO:0012501 119 0.020
negative regulation of leukocyte differentiation GO:1902106 1 0.020
cellular lipid metabolic process GO:0044255 36 0.020
protein heterooligomerization GO:0051291 1 0.020
regulation of cardiac muscle contraction GO:0055117 2 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
central nervous system development GO:0007417 387 0.019
response to organic substance GO:0010033 153 0.019
fat soluble vitamin metabolic process GO:0006775 4 0.019
heterocycle metabolic process GO:0046483 290 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
hepaticobiliary system development GO:0061008 98 0.019
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.019
cell migration GO:0016477 237 0.019
long chain fatty acid transport GO:0015909 1 0.018
regulation of transporter activity GO:0032409 2 0.018
positive regulation of biological process GO:0048518 253 0.018
heart development GO:0007507 313 0.018
sensory organ morphogenesis GO:0090596 200 0.018
regulation of rho protein signal transduction GO:0035023 2 0.018
response to hydrogen peroxide GO:0042542 3 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of catalytic activity GO:0050790 55 0.018
actin mediated cell contraction GO:0070252 1 0.018
macromolecular complex assembly GO:0065003 35 0.018
regulation of programmed cell death GO:0043067 101 0.018
embryonic organ morphogenesis GO:0048562 274 0.017
transport GO:0006810 220 0.017
regionalization GO:0003002 274 0.017
startle response GO:0001964 4 0.017
response to uv GO:0009411 3 0.017
generation of neurons GO:0048699 385 0.017
behavior GO:0007610 74 0.017
liver development GO:0001889 96 0.017
protein import GO:0017038 3 0.017
carbohydrate derivative biosynthetic process GO:1901137 43 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
single organism organelle organization GO:1902589 199 0.017
hormone metabolic process GO:0042445 19 0.017
cell aging GO:0007569 2 0.016
regulation of biological quality GO:0065008 263 0.016
regulation of cell activation GO:0050865 1 0.016
protein modification process GO:0036211 100 0.016
axon development GO:0061564 166 0.016
regulation of endothelial cell proliferation GO:0001936 1 0.016
cellular response to reactive oxygen species GO:0034614 2 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.016
protein localization to nucleus GO:0034504 3 0.016
somitogenesis GO:0001756 87 0.016
leukocyte proliferation GO:0070661 1 0.016
definitive hemopoiesis GO:0060216 18 0.016
regulation of molecular function GO:0065009 70 0.015
striated muscle cell development GO:0055002 108 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
cellular response to xenobiotic stimulus GO:0071466 35 0.015
wound healing GO:0042060 90 0.015
positive regulation of blood circulation GO:1903524 2 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
negative regulation of protein transport GO:0051224 3 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
rna metabolic process GO:0016070 219 0.015
multicellular organismal response to stress GO:0033555 2 0.014
gastrulation GO:0007369 208 0.014
nuclear import GO:0051170 3 0.014
regulation of cardiac muscle cell contraction GO:0086004 1 0.014
axon guidance GO:0007411 86 0.014
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of metabolic process GO:0009892 86 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
response to oxygen radical GO:0000305 2 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
negative chemotaxis GO:0050919 1 0.014
positive regulation of cell cycle GO:0045787 3 0.014
regulation of calcium ion transport GO:0051924 2 0.014
cellular component biogenesis GO:0044085 178 0.014
cellular hormone metabolic process GO:0034754 19 0.014
cellular response to superoxide GO:0071451 2 0.014
positive regulation of catabolic process GO:0009896 4 0.014
cellular response to organic substance GO:0071310 105 0.014
rna biosynthetic process GO:0032774 181 0.014
insulin like growth factor receptor signaling pathway GO:0048009 4 0.014
negative regulation of programmed cell death GO:0043069 58 0.013
membrane hyperpolarization GO:0060081 1 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
regulation of tube size GO:0035150 2 0.013
regulation of cell development GO:0060284 100 0.013
regulation of muscle hypertrophy GO:0014743 2 0.013
positive regulation of muscle organ development GO:0048636 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
regulation of blood vessel size GO:0050880 2 0.013
cell fate commitment GO:0045165 99 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
organic substance transport GO:0071702 58 0.013
response to hormone GO:0009725 48 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
regulation of biosynthetic process GO:0009889 250 0.013
response to superoxide GO:0000303 2 0.013
response to lipid GO:0033993 60 0.013
gtp metabolic process GO:0046039 4 0.013
response to xenobiotic stimulus GO:0009410 45 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.012
regulation of response to stress GO:0080134 36 0.012
chordate embryonic development GO:0043009 271 0.012
regulation of sodium ion transmembrane transport GO:1902305 1 0.012
removal of superoxide radicals GO:0019430 2 0.012
iron ion homeostasis GO:0055072 4 0.012
terpenoid metabolic process GO:0006721 15 0.012
cytokinesis GO:0000910 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
axonogenesis GO:0007409 152 0.012
organic anion transport GO:0015711 15 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
cell proliferation GO:0008283 80 0.012
cellular response to external stimulus GO:0071496 2 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.012
cellular response to drug GO:0035690 1 0.012
regulation of neuron projection development GO:0010975 40 0.012
lateral inhibition GO:0046331 1 0.012
germ line stem cell division GO:0042078 1 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
entrainment of circadian clock GO:0009649 2 0.011
stem cell maintenance GO:0019827 4 0.011
glycosaminoglycan biosynthetic process GO:0006024 8 0.011
commissural neuron axon guidance GO:0071679 3 0.011
mesenchyme development GO:0060485 127 0.011
positive regulation of heart contraction GO:0045823 2 0.011
diterpenoid metabolic process GO:0016101 15 0.011
cellular response to lipid GO:0071396 39 0.011
sensory perception of pain GO:0019233 1 0.011
neural crest cell differentiation GO:0014033 72 0.011
positive regulation of immune effector process GO:0002699 3 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
negative regulation of cell death GO:0060548 60 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
inner ear receptor stereocilium organization GO:0060122 8 0.011
reflex GO:0060004 2 0.011
transcription dna templated GO:0006351 181 0.011
cardiac cell development GO:0055006 21 0.011
establishment of organelle localization GO:0051656 45 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
regulation of lipid transport GO:0032368 4 0.011
regulation of localization GO:0032879 104 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
phagocytosis GO:0006909 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cation transmembrane transport GO:0098655 65 0.011
heart morphogenesis GO:0003007 156 0.011
negative regulation of chemotaxis GO:0050922 4 0.011
blood circulation GO:0008015 87 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
regulation of cell projection assembly GO:0060491 4 0.010
cation transport GO:0006812 81 0.010
cell motility GO:0048870 244 0.010
homeostasis of number of cells within a tissue GO:0048873 4 0.010
centrosome cycle GO:0007098 1 0.010
cellular response to oxygen radical GO:0071450 2 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
catecholamine metabolic process GO:0006584 2 0.010
regulation of cell shape GO:0008360 1 0.010
retinoic acid metabolic process GO:0042573 9 0.010
maintenance of location GO:0051235 4 0.010
protein targeting to nucleus GO:0044744 3 0.010
myeloid cell differentiation GO:0030099 86 0.010
energy reserve metabolic process GO:0006112 2 0.010
muscle hypertrophy GO:0014896 2 0.010
establishment of vesicle localization GO:0051650 24 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
endocrine process GO:0050886 2 0.010

ddt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
inherited metabolic disorder DOID:655 0 0.025
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
amyloidosis DOID:9120 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
bone disease DOID:0080001 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010