Danio rerio

0 known processes

pknox2

pbx/knotted 1 homeobox 2

(Aliases: prep2,zgc:136733,ft92g05,id:ibd2866,wu:ft92g05)

pknox2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid metabolic process GO:0090304 244 0.666
Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.594
Zebrafish Mouse
cellular component movement GO:0006928 335 0.580
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.519
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.519
Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.483
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.425
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.419
Zebrafish Mouse
transcription dna templated GO:0006351 181 0.407
Zebrafish Mouse
central nervous system development GO:0007417 387 0.397
Zebrafish
generation of neurons GO:0048699 385 0.387
organic substance biosynthetic process GO:1901576 289 0.376
Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.375
Zebrafish Mouse
regulation of transcription dna templated GO:0006355 213 0.375
Zebrafish Mouse
cellular biosynthetic process GO:0044249 286 0.361
Zebrafish Mouse
rna metabolic process GO:0016070 219 0.351
Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.307
Zebrafish Mouse
regionalization GO:0003002 274 0.300
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.298
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.298
Zebrafish Mouse
regulation of rna metabolic process GO:0051252 224 0.295
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.293
biosynthetic process GO:0009058 294 0.290
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.289
Zebrafish Mouse
digestive system development GO:0055123 289 0.288
Zebrafish
larval development GO:0002164 2 0.287
cellular aromatic compound metabolic process GO:0006725 295 0.280
Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.278
Zebrafish Mouse
positive regulation of cellular process GO:0048522 201 0.269
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.268
Zebrafish Mouse
nucleic acid templated transcription GO:0097659 181 0.266
Zebrafish Mouse
specification of symmetry GO:0009799 204 0.261
Zebrafish
embryonic organ development GO:0048568 381 0.241
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.227
Zebrafish Mouse
sensory organ development GO:0007423 393 0.224
Zebrafish
negative regulation of gene expression GO:0010629 65 0.214
regulation of macromolecule biosynthetic process GO:0010556 225 0.213
Zebrafish Mouse
vasculature development GO:0001944 278 0.213
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.209
Zebrafish Mouse
positive regulation of biological process GO:0048518 253 0.202
Zebrafish
regulation of metabolic process GO:0019222 359 0.194
Zebrafish Mouse
blood vessel development GO:0001568 246 0.187
Zebrafish
heterocycle metabolic process GO:0046483 290 0.187
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.175
Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.170
Zebrafish Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.166
mesenchymal cell development GO:0014031 78 0.164
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.161
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.158
Zebrafish Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.156
Zebrafish Mouse
determination of left right symmetry GO:0007368 179 0.154
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.150
Zebrafish Mouse
establishment of localization GO:0051234 244 0.148
cell fate commitment GO:0045165 99 0.148
axon development GO:0061564 166 0.145
chordate embryonic development GO:0043009 271 0.144
Zebrafish
regulation of cell differentiation GO:0045595 142 0.144
brain development GO:0007420 293 0.141
Zebrafish
gene expression GO:0010467 252 0.140
Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.140
eye development GO:0001654 277 0.139
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.135
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.134
Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.133
Zebrafish Mouse
cell migration GO:0016477 237 0.130
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.122
Zebrafish Mouse
single organism localization GO:1902578 225 0.121
pigmentation GO:0043473 85 0.117
regulation of gene expression GO:0010468 265 0.117
Zebrafish Mouse
cell projection organization GO:0030030 284 0.116
negative regulation of cellular process GO:0048523 283 0.115
regulation of anatomical structure morphogenesis GO:0022603 130 0.114
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.113
regulation of primary metabolic process GO:0080090 311 0.111
Zebrafish Mouse
tube morphogenesis GO:0035239 349 0.110
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.109
digestive tract development GO:0048565 265 0.106
locomotion GO:0040011 313 0.106
Zebrafish
heart development GO:0007507 313 0.104
Zebrafish
cell fate specification GO:0001708 68 0.099
phagocytosis GO:0006909 3 0.097
stem cell proliferation GO:0072089 4 0.097
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.095
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.095
cell morphogenesis GO:0000902 289 0.093
positive regulation of gene expression GO:0010628 71 0.093
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.092
Zebrafish Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.092
Zebrafish
regulation of developmental process GO:0050793 247 0.092
Zebrafish
appendage development GO:0048736 80 0.091
morphogenesis of an epithelium GO:0002009 333 0.088
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.088
Zebrafish
cellular component morphogenesis GO:0032989 336 0.088
camera type eye development GO:0043010 222 0.087
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.086
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.086
Zebrafish
connective tissue development GO:0061448 99 0.085
epithelial tube morphogenesis GO:0060562 148 0.083
Zebrafish
hormone secretion GO:0046879 2 0.080
cell migration involved in gastrulation GO:0042074 79 0.079
response to external stimulus GO:0009605 264 0.077
regulation of establishment of protein localization GO:0070201 4 0.077
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.077
determination of bilateral symmetry GO:0009855 204 0.077
Zebrafish
cartilage development GO:0051216 96 0.077
signal transduction GO:0007165 455 0.076
Zebrafish
regulation of signaling GO:0023051 235 0.076
Zebrafish
regulation of cellular component organization GO:0051128 86 0.074
muscle organ development GO:0007517 101 0.073
apoptotic process GO:0006915 116 0.073
positive regulation of nucleic acid templated transcription GO:1903508 57 0.072
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.071
stem cell differentiation GO:0048863 117 0.071
regulation of multicellular organismal development GO:2000026 223 0.071
Zebrafish
aging GO:0007568 2 0.071
reproductive process GO:0022414 40 0.071
regulation of rna biosynthetic process GO:2001141 213 0.070
Zebrafish Mouse
compound eye development GO:0048749 2 0.069
female sex differentiation GO:0046660 4 0.067
death GO:0016265 121 0.067
forebrain development GO:0030900 96 0.066
Zebrafish
action potential GO:0001508 19 0.066
regulation of cell development GO:0060284 100 0.066
glial cell differentiation GO:0010001 42 0.066
programmed cell death GO:0012501 119 0.065
neural crest cell differentiation GO:0014033 72 0.065
negative regulation of transcription dna templated GO:0045892 45 0.065
organic cyclic compound metabolic process GO:1901360 301 0.065
Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.064
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.064
Zebrafish
response to chemical GO:0042221 320 0.064
Zebrafish
transmission of nerve impulse GO:0019226 19 0.063
cell projection morphogenesis GO:0048858 244 0.063
immune system process GO:0002376 241 0.063
Zebrafish
ear development GO:0043583 127 0.063
inner ear development GO:0048839 126 0.062
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.062
eye morphogenesis GO:0048592 144 0.061
Zebrafish
stem cell development GO:0048864 82 0.060
embryonic skeletal system morphogenesis GO:0048704 93 0.060
Zebrafish
cell part morphogenesis GO:0032990 246 0.059
head development GO:0060322 303 0.059
Zebrafish
localization of cell GO:0051674 244 0.058
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.058
Zebrafish
negative regulation of biosynthetic process GO:0009890 55 0.058
establishment of protein localization to organelle GO:0072594 4 0.058
kidney development GO:0001822 92 0.058
ameboidal type cell migration GO:0001667 143 0.055
negative regulation of rna metabolic process GO:0051253 48 0.055
gliogenesis GO:0042063 45 0.054
cognition GO:0050890 1 0.054
response to organic substance GO:0010033 153 0.054
Zebrafish
neuron projection development GO:0031175 180 0.054
regulation of dendrite development GO:0050773 3 0.054
protein secretion GO:0009306 1 0.054
primary neural tube formation GO:0014020 1 0.053
positive regulation of biosynthetic process GO:0009891 68 0.053
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.053
Zebrafish
gastrulation GO:0007369 208 0.053
positive regulation of transport GO:0051050 2 0.053
system process GO:0003008 185 0.052
regulation of multicellular organism growth GO:0040014 4 0.052
transport GO:0006810 220 0.052
regulation of dendrite morphogenesis GO:0048814 3 0.051
endocrine system development GO:0035270 65 0.051
cell death GO:0008219 121 0.051
segmentation GO:0035282 97 0.051
embryonic heart tube morphogenesis GO:0003143 108 0.050
Zebrafish
negative regulation of rna biosynthetic process GO:1902679 45 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.049
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.049
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.048
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.048
Zebrafish
negative regulation of nucleic acid templated transcription GO:1903507 45 0.048
lipid storage GO:0019915 1 0.047
neuron projection morphogenesis GO:0048812 161 0.047
spinal cord development GO:0021510 46 0.047
regulation of membrane potential GO:0042391 23 0.047
negative regulation of cellular biosynthetic process GO:0031327 55 0.046
renal system development GO:0072001 94 0.046
negative regulation of protein phosphorylation GO:0001933 4 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.046
Zebrafish
single organism metabolic process GO:0044710 217 0.045
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.045
embryonic limb morphogenesis GO:0030326 2 0.044
positive regulation of rna biosynthetic process GO:1902680 57 0.044
Zebrafish
cellular response to organic substance GO:0071310 105 0.044
Zebrafish
neural crest cell development GO:0014032 62 0.043
cellular protein metabolic process GO:0044267 129 0.042
peptidyl lysine acetylation GO:0018394 2 0.042
mesenchyme development GO:0060485 127 0.041
photoreceptor cell differentiation GO:0046530 55 0.041
urogenital system development GO:0001655 97 0.041
gtp catabolic process GO:0006184 2 0.041
neuron development GO:0048666 262 0.041
pancreas development GO:0031016 84 0.040
Zebrafish
embryonic heart tube development GO:0035050 133 0.040
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.040
regulation of neurogenesis GO:0050767 87 0.040
cell proliferation GO:0008283 80 0.039
Zebrafish
skeletal system development GO:0001501 181 0.039
Zebrafish
internal protein amino acid acetylation GO:0006475 2 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.039
Zebrafish
positive regulation of secretion GO:0051047 1 0.039
neural tube development GO:0021915 62 0.039
positive regulation of secretion by cell GO:1903532 1 0.038
regulation of response to stimulus GO:0048583 269 0.038
Zebrafish
multicellular organism growth GO:0035264 4 0.038
endocrine pancreas development GO:0031018 27 0.037
regulation of cell death GO:0010941 103 0.037
cellular response to chemical stimulus GO:0070887 157 0.036
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.036
Zebrafish
convergent extension GO:0060026 118 0.036
regulation of reproductive process GO:2000241 4 0.036
exocytosis GO:0006887 1 0.036
tube closure GO:0060606 1 0.035
heart looping GO:0001947 94 0.035
Zebrafish
regulation of biological quality GO:0065008 263 0.035
Zebrafish
development of primary female sexual characteristics GO:0046545 4 0.035
guanosine containing compound metabolic process GO:1901068 4 0.035
positive regulation of cellular metabolic process GO:0031325 94 0.035
Zebrafish
nuclear import GO:0051170 3 0.035
cellular component assembly GO:0022607 170 0.034
protein import into nucleus GO:0006606 3 0.034
cell motility GO:0048870 244 0.034
Zebrafish
embryonic skeletal system development GO:0048706 97 0.034
Zebrafish
lens development in camera type eye GO:0002088 22 0.033
regulation of epithelial cell proliferation GO:0050678 3 0.033
nuclear transport GO:0051169 4 0.032
regulation of signal transduction GO:0009966 225 0.032
Zebrafish
muscle tissue development GO:0060537 110 0.032
regulation of protein transport GO:0051223 3 0.032
gtp metabolic process GO:0046039 4 0.031
response to drug GO:0042493 3 0.031
developmental pigmentation GO:0048066 48 0.031
embryonic organ morphogenesis GO:0048562 274 0.031
Zebrafish
cell cycle g1 s phase transition GO:0044843 1 0.031
Zebrafish
appendage morphogenesis GO:0035107 56 0.030
olfactory bulb development GO:0021772 4 0.030
negative regulation of response to stimulus GO:0048585 104 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
central nervous system myelination GO:0022010 2 0.029
cellular protein modification process GO:0006464 100 0.029
skeletal muscle organ development GO:0060538 78 0.029
nerve development GO:0021675 45 0.029
cell projection assembly GO:0030031 64 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.028
Zebrafish
neuronal action potential GO:0019228 18 0.028
regulation of bmp signaling pathway GO:0030510 39 0.028
developmental growth GO:0048589 166 0.028
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.028
Zebrafish
protein acetylation GO:0006473 2 0.028
somite development GO:0061053 96 0.028
embryonic cranial skeleton morphogenesis GO:0048701 90 0.028
Zebrafish
chemosensory behavior GO:0007635 1 0.028
neuroblast proliferation GO:0007405 2 0.027
determination of heart left right asymmetry GO:0061371 117 0.027
Zebrafish
regulation of binding GO:0051098 3 0.027
lens morphogenesis in camera type eye GO:0002089 7 0.027
heart morphogenesis GO:0003007 156 0.027
Zebrafish
pigment cell differentiation GO:0050931 38 0.027
regulation of synapse assembly GO:0051963 3 0.026
neuron projection guidance GO:0097485 86 0.026
erythrocyte differentiation GO:0030218 54 0.026
Zebrafish
regulation of protein ubiquitination GO:0031396 3 0.026
establishment of blood brain barrier GO:0060856 2 0.026
regulation of cell communication GO:0010646 232 0.026
Zebrafish
protein targeting to nucleus GO:0044744 3 0.026
neurological system process GO:0050877 62 0.025
regulation of synapse organization GO:0050807 3 0.025
behavior GO:0007610 74 0.025
protein localization to nucleus GO:0034504 3 0.025
somitogenesis GO:0001756 87 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.025
Zebrafish
anterior posterior axis specification GO:0009948 20 0.025
homeostatic process GO:0042592 142 0.025
Zebrafish
ectodermal placode development GO:0071696 37 0.024
cellular ketone metabolic process GO:0042180 11 0.024
multi organism process GO:0051704 134 0.024
positive regulation of cell cycle GO:0045787 3 0.024
positive regulation of developmental process GO:0051094 50 0.024
Zebrafish
negative regulation of catabolic process GO:0009895 3 0.024
retina development in camera type eye GO:0060041 146 0.024
Zebrafish
organelle organization GO:0006996 227 0.024
embryonic camera type eye development GO:0031076 29 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
lateral line system development GO:0048925 76 0.024
maintenance of location GO:0051235 4 0.024
regulation of programmed cell death GO:0043067 101 0.023
multicellular organismal signaling GO:0035637 22 0.023
axon ensheathment GO:0008366 18 0.023
central nervous system neuron differentiation GO:0021953 74 0.023
gland development GO:0048732 143 0.023
regulation of protein targeting GO:1903533 2 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
organic substance transport GO:0071702 58 0.023
single organism nuclear import GO:1902593 3 0.023
outflow tract morphogenesis GO:0003151 1 0.023
striated muscle tissue development GO:0014706 110 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
regulation of neuron projection development GO:0010975 40 0.022
single organism organelle organization GO:1902589 199 0.022
stem cell division GO:0017145 1 0.022
heart jogging GO:0003146 40 0.022
hepaticobiliary system development GO:0061008 98 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
Zebrafish
hemopoiesis GO:0030097 183 0.022
Zebrafish
regulation of localization GO:0032879 104 0.022
axonogenesis GO:0007409 152 0.022
peptidyl serine modification GO:0018209 2 0.022
sexual reproduction GO:0019953 36 0.022
protein localization to plasma membrane GO:0072659 1 0.021
cilium organization GO:0044782 71 0.021
axon guidance GO:0007411 86 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
single organism transport GO:0044765 206 0.021
negative regulation of multicellular organismal process GO:0051241 69 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.021
regeneration GO:0031099 91 0.021
Zebrafish
bmp signaling pathway GO:0030509 52 0.021
negative regulation of signaling GO:0023057 96 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
artery development GO:0060840 22 0.021
Zebrafish
photoreceptor cell fate commitment GO:0046552 1 0.021
tissue regeneration GO:0042246 74 0.021
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.021
Zebrafish
macromolecule modification GO:0043412 111 0.021
carbohydrate homeostasis GO:0033500 1 0.021
dna templated transcription initiation GO:0006352 1 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
hair cell differentiation GO:0035315 32 0.020
cell growth GO:0016049 57 0.020
ensheathment of neurons GO:0007272 18 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
regulation of stem cell proliferation GO:0072091 2 0.020
Zebrafish
regulation of nervous system development GO:0051960 90 0.020
proximal distal pattern formation GO:0009954 1 0.020
regulation of erk1 and erk2 cascade GO:0070372 4 0.020
protein modification process GO:0036211 100 0.020
neuron fate commitment GO:0048663 26 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
synaptic target recognition GO:0008039 1 0.019
fin development GO:0033333 77 0.019
peptide transport GO:0015833 1 0.019
regulation of cell motility GO:2000145 46 0.019
negative regulation of signal transduction GO:0009968 94 0.019
protein acylation GO:0043543 3 0.019
membrane invagination GO:0010324 1 0.019
epidermis development GO:0008544 48 0.019
membrane fusion GO:0061025 2 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
negative regulation of cell death GO:0060548 60 0.019
developmental process involved in reproduction GO:0003006 27 0.018
secondary metabolic process GO:0019748 3 0.018
olfactory lobe development GO:0021988 4 0.018
positive regulation of stress activated mapk cascade GO:0032874 3 0.018
mechanoreceptor differentiation GO:0042490 37 0.018
sympathetic nervous system development GO:0048485 3 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
muscle structure development GO:0061061 196 0.018
fin regeneration GO:0031101 51 0.018
sprouting angiogenesis GO:0002040 53 0.018
peptidyl threonine phosphorylation GO:0018107 1 0.018
oxoacid metabolic process GO:0043436 31 0.018
response to endogenous stimulus GO:0009719 83 0.018
Zebrafish
regulation of jak stat cascade GO:0046425 3 0.018
inner ear morphogenesis GO:0042472 63 0.018
protein metabolic process GO:0019538 183 0.017
fertilization GO:0009566 3 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
neural crest cell migration GO:0001755 42 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.017
retina layer formation GO:0010842 24 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
negative regulation of ras protein signal transduction GO:0046580 1 0.017
endoderm development GO:0007492 49 0.017
cellular localization GO:0051641 97 0.017
cellular component biogenesis GO:0044085 178 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
Zebrafish
response to monosaccharide GO:0034284 3 0.017
stem cell maintenance GO:0019827 4 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
antimicrobial humoral response GO:0019730 2 0.016
regulation of chondrocyte differentiation GO:0032330 1 0.016
meiotic nuclear division GO:0007126 4 0.016
regulation of cell projection assembly GO:0060491 4 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
multi organism reproductive process GO:0044703 36 0.016
pectoral fin development GO:0033339 50 0.016
protein localization GO:0008104 40 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.016
neural precursor cell proliferation GO:0061351 20 0.016
adult behavior GO:0030534 2 0.016
cilium assembly GO:0042384 58 0.016
intracellular receptor signaling pathway GO:0030522 30 0.016
Zebrafish
angiogenesis GO:0001525 158 0.016
Zebrafish
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.016
regulation of gene expression epigenetic GO:0040029 11 0.016
forebrain cell migration GO:0021885 1 0.016
regulation of cytokine production GO:0001817 3 0.015
regulation of cellular response to growth factor stimulus GO:0090287 35 0.015
Zebrafish
pericardium development GO:0060039 1 0.015
cranial nerve development GO:0021545 42 0.015
response to abiotic stimulus GO:0009628 122 0.015
organic acid metabolic process GO:0006082 31 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
inner ear receptor cell differentiation GO:0060113 29 0.015
epithelial cell differentiation GO:0030855 116 0.015
Zebrafish
melanin metabolic process GO:0006582 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
neuromast development GO:0048884 46 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
lateral line development GO:0048882 66 0.015
taxis GO:0042330 109 0.015
circulatory system process GO:0003013 87 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
regulation of exocytosis GO:0017157 1 0.015
negative regulation of nervous system development GO:0051961 22 0.015
chemotaxis GO:0006935 104 0.015
cellular amine metabolic process GO:0044106 2 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
glucose import GO:0046323 2 0.014
cell differentiation in spinal cord GO:0021515 40 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
somatic stem cell maintenance GO:0035019 1 0.014
negative regulation of neurogenesis GO:0050768 20 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
cell cycle arrest GO:0007050 1 0.014
regulation of embryonic development GO:0045995 47 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
telencephalon development GO:0021537 14 0.014
embryonic hemopoiesis GO:0035162 53 0.014
Zebrafish
positive regulation of stem cell proliferation GO:2000648 1 0.014
midbrain development GO:0030901 28 0.014
negative regulation of cell differentiation GO:0045596 46 0.014
protein import GO:0017038 3 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
hormone transport GO:0009914 2 0.014
regulation of circadian rhythm GO:0042752 4 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
axis specification GO:0009798 43 0.014
central nervous system myelin formation GO:0032289 1 0.014
hindbrain development GO:0030902 91 0.014
Zebrafish
axon extension GO:0048675 45 0.014
cellular protein catabolic process GO:0044257 4 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
pharyngeal muscle development GO:0043282 4 0.013
cell substrate adhesion GO:0031589 4 0.013
locomotory behavior GO:0007626 34 0.013
sensory system development GO:0048880 76 0.013
gastrulation with mouth forming second GO:0001702 44 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of cell migration GO:0030334 40 0.013
cilium morphogenesis GO:0060271 85 0.013
photoreceptor cell development GO:0042461 40 0.013
phagocytosis engulfment GO:0006911 1 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
regulation of cellular component movement GO:0051270 55 0.013
diencephalon development GO:0021536 58 0.013
response to carbohydrate GO:0009743 3 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
Zebrafish
embryonic pattern specification GO:0009880 44 0.013
Zebrafish
positive regulation of cell adhesion GO:0045785 1 0.013
negative regulation of kinase activity GO:0033673 4 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
pronephros development GO:0048793 69 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
neuron projection extension GO:1990138 45 0.012
photoreceptor cell fate specification GO:0043704 1 0.012
cardiocyte differentiation GO:0035051 44 0.012
regulation of cell shape GO:0008360 1 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
regulation of locomotion GO:0040012 55 0.012
peptidyl threonine modification GO:0018210 1 0.012
striated muscle cell differentiation GO:0051146 129 0.012
skin development GO:0043588 54 0.012
epidermal cell differentiation GO:0009913 36 0.012
mechanosensory behavior GO:0007638 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
response to hexose GO:0009746 3 0.012
phosphorus metabolic process GO:0006793 109 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
morphogenesis of an epithelial sheet GO:0002011 49 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
wnt signaling pathway GO:0016055 80 0.012

pknox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039