Danio rerio

0 known processes

ptpn2b

protein tyrosine phosphatase, non-receptor type 2, b

(Aliases: zgc:55339,wu:fc10h07,PTP-1B,cb806,zgc:76973,ptpn2,ptpn2l)

ptpn2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle metabolic process GO:0046483 290 0.109
organic substance biosynthetic process GO:1901576 289 0.094
Mouse
larval development GO:0002164 2 0.065
signal transduction GO:0007165 455 0.058
Human Mouse
golgi vesicle transport GO:0048193 3 0.052
meiotic nuclear division GO:0007126 4 0.050
fatty acid biosynthetic process GO:0006633 4 0.048
multicellular organism growth GO:0035264 4 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.040
positive regulation of catabolic process GO:0009896 4 0.036
macromolecule biosynthetic process GO:0009059 227 0.036
ribonucleoside monophosphate catabolic process GO:0009158 4 0.036
long chain fatty acid metabolic process GO:0001676 1 0.035
cortical cytoskeleton organization GO:0030865 1 0.034
protein import into nucleus GO:0006606 3 0.033
modification dependent macromolecule catabolic process GO:0043632 3 0.032
positive regulation of cell cycle GO:0045787 3 0.032
regulation of tube size GO:0035150 2 0.031
proteasomal protein catabolic process GO:0010498 2 0.031
regionalization GO:0003002 274 0.030
epithelial cell morphogenesis GO:0003382 2 0.030
regulation of gene expression GO:0010468 265 0.029
purine nucleoside monophosphate catabolic process GO:0009128 4 0.028
aging GO:0007568 2 0.028
nucleic acid metabolic process GO:0090304 244 0.027
cytokinesis GO:0000910 3 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.025
Human Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
epithelial cell differentiation GO:0030855 116 0.024
response to stress GO:0006950 263 0.024
Human Mouse
angiogenesis GO:0001525 158 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
development of primary female sexual characteristics GO:0046545 4 0.023
organic cyclic compound metabolic process GO:1901360 301 0.022
meiotic cell cycle process GO:1903046 3 0.022
mitotic cell cycle GO:0000278 64 0.021
positive regulation of transport GO:0051050 2 0.021
compound eye development GO:0048749 2 0.021
sulfur compound metabolic process GO:0006790 13 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
Human Mouse
positive regulation of map kinase activity GO:0043406 3 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
protein secretion GO:0009306 1 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
cell part morphogenesis GO:0032990 246 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
Human Mouse
cell substrate junction assembly GO:0007044 2 0.020
regulation of sodium ion transport GO:0002028 2 0.020
programmed cell death GO:0012501 119 0.020
cell morphogenesis GO:0000902 289 0.020
gastrulation GO:0007369 208 0.019
cell migration GO:0016477 237 0.019
adherens junction organization GO:0034332 4 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
female meiotic division GO:0007143 2 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
estrogen metabolic process GO:0008210 2 0.019
small molecule metabolic process GO:0044281 77 0.018
Mouse
atp catabolic process GO:0006200 4 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
phosphorylation GO:0016310 69 0.018
Human Mouse
gtp metabolic process GO:0046039 4 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
Mouse
cellular protein metabolic process GO:0044267 129 0.018
Human Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
regulation of receptor mediated endocytosis GO:0048259 4 0.018
stem cell division GO:0017145 1 0.018
chromosome organization involved in meiosis GO:0070192 1 0.017
regulation of blood vessel size GO:0050880 2 0.017
organic acid metabolic process GO:0006082 31 0.016
lipid homeostasis GO:0055088 3 0.016
negative regulation of cellular process GO:0048523 283 0.016
Human Mouse
g protein coupled receptor signaling pathway GO:0007186 74 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
regulation of protein transport GO:0051223 3 0.016
response to vitamin GO:0033273 3 0.016
locomotor rhythm GO:0045475 3 0.016
striated muscle tissue development GO:0014706 110 0.016
regulation of metabolic process GO:0019222 359 0.016
Human Mouse
cortical actin cytoskeleton organization GO:0030866 1 0.015
mitochondrion organization GO:0007005 4 0.015
cytokinetic process GO:0032506 2 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
central nervous system development GO:0007417 387 0.015
cellular response to radiation GO:0071478 4 0.015
death GO:0016265 121 0.015
regulation of cell matrix adhesion GO:0001952 1 0.015
hormone transport GO:0009914 2 0.015
regulation of transporter activity GO:0032409 2 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
positive regulation of translation GO:0045727 1 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Mouse
cell death GO:0008219 121 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
rna metabolic process GO:0016070 219 0.014
regulation of biological quality GO:0065008 263 0.014
Mouse
lipid storage GO:0019915 1 0.014
Mouse
regulation of reproductive process GO:2000241 4 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
regulation of response to stimulus GO:0048583 269 0.014
Human Mouse
phagocytosis GO:0006909 3 0.014
response to drug GO:0042493 3 0.014
digestive system development GO:0055123 289 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
Mouse
localization of cell GO:0051674 244 0.014
cell junction organization GO:0034330 11 0.014
regulation of myotube differentiation GO:0010830 2 0.014
regulation of signal transduction GO:0009966 225 0.014
Human Mouse
limb bud formation GO:0060174 2 0.014
antimicrobial humoral response GO:0019730 2 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.013
organonitrogen compound biosynthetic process GO:1901566 47 0.013
neurotransmitter transport GO:0006836 2 0.013
cellular macromolecule metabolic process GO:0044260 391 0.013
Human Mouse
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
single organism localization GO:1902578 225 0.013
negative regulation of kinase activity GO:0033673 4 0.013
muscle organ development GO:0007517 101 0.013
endosomal transport GO:0016197 2 0.013
nuclear transport GO:0051169 4 0.013
gtp catabolic process GO:0006184 2 0.013
behavior GO:0007610 74 0.013
Mouse
regulation of rna metabolic process GO:0051252 224 0.013
muscle structure development GO:0061061 196 0.013
response to external biotic stimulus GO:0043207 97 0.012
system process GO:0003008 185 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
cellular protein modification process GO:0006464 100 0.012
Human Mouse
epithelial cell development GO:0002064 42 0.012
cellular modified amino acid metabolic process GO:0006575 3 0.012
adult behavior GO:0030534 2 0.012
coenzyme biosynthetic process GO:0009108 2 0.012
peptidyl serine modification GO:0018209 2 0.012
skeletal muscle organ development GO:0060538 78 0.012
maintenance of location GO:0051235 4 0.012
Mouse
carboxylic acid metabolic process GO:0019752 22 0.012
regulation of oocyte development GO:0060281 3 0.012
regulation of primary metabolic process GO:0080090 311 0.012
Human Mouse
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
regulation of dna replication GO:0006275 3 0.012
cellular biosynthetic process GO:0044249 286 0.012
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.012
nitrogen compound metabolic process GO:0006807 319 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
establishment of vesicle localization GO:0051650 24 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
cellular protein catabolic process GO:0044257 4 0.011
female sex differentiation GO:0046660 4 0.011
neurotransmitter secretion GO:0007269 2 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
hormone secretion GO:0046879 2 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
blood vessel development GO:0001568 246 0.011
Zebrafish
regulation of organ growth GO:0046620 3 0.011
blood vessel morphogenesis GO:0048514 216 0.011
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.011
Human Mouse
protein metabolic process GO:0019538 183 0.011
Human Mouse
cellular respiration GO:0045333 3 0.011
growth GO:0040007 174 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
receptor recycling GO:0001881 4 0.011
rna localization GO:0006403 4 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
regulation of chromosome segregation GO:0051983 1 0.011
single organism metabolic process GO:0044710 217 0.011
Mouse
organism emergence from protective structure GO:0071684 4 0.011
female gonad development GO:0008585 4 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
negative regulation of developmental process GO:0051093 65 0.011
Mouse
negative regulation of mapk cascade GO:0043409 4 0.011
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
nuclear import GO:0051170 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.010
cellular component biogenesis GO:0044085 178 0.010
negative regulation of cell communication GO:0010648 96 0.010
Human Mouse
fatty acid elongation GO:0030497 1 0.010
oocyte maturation GO:0001556 4 0.010
synaptic vesicle transport GO:0048489 1 0.010
regulation of cytokine production GO:0001817 3 0.010
regulation of cell death GO:0010941 103 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
melanosome transport GO:0032402 19 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
rna biosynthetic process GO:0032774 181 0.010

ptpn2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.014
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011