Danio rerio

0 known processes

ptpn2a

protein tyrosine phosphatase, non-receptor type 2, a

(Aliases: MGC63623,PTP-1B,zgc:63623,hm:zeh1546,ptpn2)

ptpn2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.091
meiotic nuclear division GO:0007126 4 0.054
nitrogen compound metabolic process GO:0006807 319 0.045
cellular macromolecule metabolic process GO:0044260 391 0.045
Human
larval development GO:0002164 2 0.044
protein polyubiquitination GO:0000209 4 0.043
cellular nitrogen compound metabolic process GO:0034641 290 0.039
heterocycle metabolic process GO:0046483 290 0.039
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.039
nucleic acid metabolic process GO:0090304 244 0.036
lipid storage GO:0019915 1 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.034
modification dependent protein catabolic process GO:0019941 3 0.034
regulation of protein catabolic process GO:0042176 1 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
positive regulation of catabolic process GO:0009896 4 0.032
cellular protein metabolic process GO:0044267 129 0.031
Human
cellular protein modification process GO:0006464 100 0.031
Human
positive regulation of transport GO:0051050 2 0.031
multicellular organism growth GO:0035264 4 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
catecholamine metabolic process GO:0006584 2 0.028
autophagy GO:0006914 4 0.028
maintenance of location GO:0051235 4 0.027
organelle organization GO:0006996 227 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
positive regulation of cellular process GO:0048522 201 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
protein polymerization GO:0051258 4 0.026
cellular protein catabolic process GO:0044257 4 0.025
cell aging GO:0007569 2 0.025
female sex differentiation GO:0046660 4 0.025
cell migration GO:0016477 237 0.025
meiotic cell cycle process GO:1903046 3 0.024
chromosome organization involved in meiosis GO:0070192 1 0.024
nuclear export GO:0051168 1 0.023
proteasomal protein catabolic process GO:0010498 2 0.022
regulation of binding GO:0051098 3 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
cellular component movement GO:0006928 335 0.022
female gonad development GO:0008585 4 0.022
response to ketone GO:1901654 1 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
regulation of protein ubiquitination GO:0031396 3 0.021
rna metabolic process GO:0016070 219 0.021
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.021
cellular response to external stimulus GO:0071496 2 0.021
protein metabolic process GO:0019538 183 0.020
Human
cellular response to extracellular stimulus GO:0031668 2 0.020
mitotic dna integrity checkpoint GO:0044774 4 0.020
cellular response to starvation GO:0009267 1 0.020
leukocyte proliferation GO:0070661 1 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
regulation of reproductive process GO:2000241 4 0.020
mononuclear cell proliferation GO:0032943 1 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
development of primary female sexual characteristics GO:0046545 4 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
endosomal transport GO:0016197 2 0.019
b cell activation GO:0042113 2 0.019
golgi vesicle transport GO:0048193 3 0.019
tube morphogenesis GO:0035239 349 0.019
response to stress GO:0006950 263 0.019
Human
vacuolar transport GO:0007034 2 0.019
mitotic dna damage checkpoint GO:0044773 4 0.018
regulation of hormone secretion GO:0046883 2 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
macromolecule modification GO:0043412 111 0.018
Human
regulation of mrna processing GO:0050684 3 0.018
regulation of cell activation GO:0050865 1 0.018
establishment of localization GO:0051234 244 0.018
cellular response to nutrient levels GO:0031669 2 0.018
transport GO:0006810 220 0.018
heart development GO:0007507 313 0.018
amine metabolic process GO:0009308 2 0.018
gene expression GO:0010467 252 0.018
regulation of protein complex assembly GO:0043254 3 0.018
spermatid differentiation GO:0048515 2 0.018
single organism metabolic process GO:0044710 217 0.018
regulation of chromosome segregation GO:0051983 1 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
spermatid development GO:0007286 2 0.017
meiotic chromosome segregation GO:0045132 3 0.017
stem cell maintenance GO:0019827 4 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.017
double strand break repair GO:0006302 3 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
protein import into nucleus GO:0006606 3 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
regulation of rna metabolic process GO:0051252 224 0.017
positive regulation of biological process GO:0048518 253 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
brain development GO:0007420 293 0.017
mitochondrion organization GO:0007005 4 0.017
b cell differentiation GO:0030183 1 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
nuclear transport GO:0051169 4 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
spindle assembly GO:0051225 2 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
meiosis i GO:0007127 1 0.016
positive regulation of cell cycle GO:0045787 3 0.016
regulation of protein transport GO:0051223 3 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
protein modification process GO:0036211 100 0.016
Human
tissue remodeling GO:0048771 4 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
regulation of metabolic process GO:0019222 359 0.016
Human
embryonic organ development GO:0048568 381 0.016
covalent chromatin modification GO:0016569 20 0.016
regulation of cytokine production GO:0001817 3 0.016
cellular component biogenesis GO:0044085 178 0.016
cell substrate adhesion GO:0031589 4 0.016
locomotion GO:0040011 313 0.016
regulation of inflammatory response GO:0050727 2 0.016
nuclear import GO:0051170 3 0.016
negative regulation of biological process GO:0048519 304 0.015
Human
regulation of primary metabolic process GO:0080090 311 0.015
Human
central nervous system development GO:0007417 387 0.015
regulation of tube size GO:0035150 2 0.015
chromosome organization GO:0051276 31 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
nik nf kappab signaling GO:0038061 1 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
Human
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
histone modification GO:0016570 20 0.015
organic substance biosynthetic process GO:1901576 289 0.015
sensory organ development GO:0007423 393 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
catechol containing compound metabolic process GO:0009712 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
response to corticosteroid GO:0031960 1 0.015
rna localization GO:0006403 4 0.015
stem cell proliferation GO:0072089 4 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
camera type eye development GO:0043010 222 0.015
head development GO:0060322 303 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
alternative mrna splicing via spliceosome GO:0000380 1 0.015
hormone secretion GO:0046879 2 0.015
cell matrix adhesion GO:0007160 4 0.014
negative regulation of cellular process GO:0048523 283 0.014
Human
positive regulation of cytoskeleton organization GO:0051495 3 0.014
cellular component disassembly GO:0022411 1 0.014
protein import GO:0017038 3 0.014
membrane lipid biosynthetic process GO:0046467 2 0.014
mitotic g2 dna damage checkpoint GO:0007095 3 0.014
dna templated transcription elongation GO:0006354 3 0.014
digestive system development GO:0055123 289 0.014
eye development GO:0001654 277 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
protein localization to nucleus GO:0034504 3 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
endocrine process GO:0050886 2 0.014
cellular biosynthetic process GO:0044249 286 0.014
er to golgi vesicle mediated transport GO:0006888 1 0.014
positive regulation of immune effector process GO:0002699 3 0.014
cellular amine metabolic process GO:0044106 2 0.014
neuroblast proliferation GO:0007405 2 0.014
response to carbohydrate GO:0009743 3 0.014
somatic muscle development GO:0007525 4 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
actin filament polymerization GO:0030041 2 0.014
adult behavior GO:0030534 2 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
response to uv GO:0009411 3 0.014
synaptic vesicle transport GO:0048489 1 0.014
regulation of synapse organization GO:0050807 3 0.014
microtubule polymerization or depolymerization GO:0031109 3 0.014
positive regulation of cell activation GO:0050867 1 0.014
single organism nuclear import GO:1902593 3 0.014
positive regulation of cytokine production GO:0001819 2 0.014
regulation of blood pressure GO:0008217 1 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
lymphocyte proliferation GO:0046651 1 0.014
organelle fusion GO:0048284 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
carboxylic acid metabolic process GO:0019752 22 0.013
hormone transport GO:0009914 2 0.013
chromatin modification GO:0016568 21 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of cell shape GO:0008360 1 0.013
generation of neurons GO:0048699 385 0.013
odontogenesis of dentin containing tooth GO:0042475 1 0.013
regulation of jak stat cascade GO:0046425 3 0.013
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
cellular component assembly GO:0022607 170 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
Human
oxoacid metabolic process GO:0043436 31 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
heart looping GO:0001947 94 0.013
phagocytosis GO:0006909 3 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
negative regulation of cytokine production GO:0001818 1 0.013
positive regulation of secretion GO:0051047 1 0.013
single organism transport GO:0044765 206 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
regulation of synapse assembly GO:0051963 3 0.013
regulation of protein polymerization GO:0032271 2 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of dna replication GO:0006275 3 0.013
cellular localization GO:0051641 97 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
transcription dna templated GO:0006351 181 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
synapsis GO:0007129 1 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of blood vessel size GO:0050880 2 0.012
response to drug GO:0042493 3 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
response to hexose GO:0009746 3 0.012
response to vitamin GO:0033273 3 0.012
pancreas development GO:0031016 84 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
cellular response to dna damage stimulus GO:0006974 24 0.012
regulation of gene expression GO:0010468 265 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
gastrulation GO:0007369 208 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
regulation of developmental process GO:0050793 247 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
biosynthetic process GO:0009058 294 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
response to monosaccharide GO:0034284 3 0.012
regulation of transcription dna templated GO:0006355 213 0.012
response to external stimulus GO:0009605 264 0.012
pharyngeal muscle development GO:0043282 4 0.012
protein localization to plasma membrane GO:0072659 1 0.012
positive regulation of translation GO:0045727 1 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
rna 3 end processing GO:0031123 2 0.012
cellular component morphogenesis GO:0032989 336 0.012
regulation of signal transduction GO:0009966 225 0.012
Human
regulation of intracellular protein transport GO:0033157 3 0.012
immunoglobulin mediated immune response GO:0016064 3 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
primary neural tube formation GO:0014020 1 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
protein k48 linked ubiquitination GO:0070936 1 0.011
protein acylation GO:0043543 3 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
negative regulation of secretion GO:0051048 2 0.011
single organism organelle organization GO:1902589 199 0.011
tube closure GO:0060606 1 0.011
rna transport GO:0050658 2 0.011
regulation of protein targeting GO:1903533 2 0.011
lipid homeostasis GO:0055088 3 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
protein targeting to nucleus GO:0044744 3 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
Human
spindle assembly involved in mitosis GO:0090307 1 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
growth GO:0040007 174 0.011
glucose homeostasis GO:0042593 1 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
regulation of organ growth GO:0046620 3 0.011
peptide transport GO:0015833 1 0.011
somatic stem cell maintenance GO:0035019 1 0.011
positive regulation of metabolic process GO:0009893 108 0.011
b cell mediated immunity GO:0019724 3 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
hemopoiesis GO:0030097 183 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of metal ion transport GO:0010959 4 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
stem cell division GO:0017145 1 0.011
cellular ketone metabolic process GO:0042180 11 0.011
nucleic acid templated transcription GO:0097659 181 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
homeostatic process GO:0042592 142 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
positive regulation of gene expression GO:0010628 71 0.011
immunoglobulin production GO:0002377 1 0.011
indole containing compound metabolic process GO:0042430 2 0.011
protein complex disassembly GO:0043241 1 0.011
cell projection morphogenesis GO:0048858 244 0.011
pronephros development GO:0048793 69 0.011
positive regulation of histone modification GO:0031058 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
protein acetylation GO:0006473 2 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
glycerophospholipid biosynthetic process GO:0046474 1 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
Human
nitric oxide metabolic process GO:0046209 2 0.010
positive regulation of striated muscle tissue development GO:0045844 1 0.010
glycerolipid biosynthetic process GO:0045017 1 0.010
leukocyte homeostasis GO:0001776 2 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
protein modification by small protein removal GO:0070646 1 0.010
response to nutrient GO:0007584 3 0.010
atp catabolic process GO:0006200 4 0.010
nucleic acid transport GO:0050657 2 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
gtp metabolic process GO:0046039 4 0.010
regulation of dna recombination GO:0000018 2 0.010
regulation of biosynthetic process GO:0009889 250 0.010
ribosome assembly GO:0042255 1 0.010
developmental programmed cell death GO:0010623 4 0.010
regulation of receptor mediated endocytosis GO:0048259 4 0.010
immune system process GO:0002376 241 0.010
Human
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
lamellipodium organization GO:0097581 1 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010

ptpn2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.014
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.011