Danio rerio

44 known processes

ptpn21

protein tyrosine phosphatase, non-receptor type 21

(Aliases: pez,ptpn14)

ptpn21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly GO:0022607 170 0.305
cellular macromolecule metabolic process GO:0044260 391 0.251
heart development GO:0007507 313 0.220
nitrogen compound metabolic process GO:0006807 319 0.216
positive regulation of cellular component biogenesis GO:0044089 3 0.195
cellular macromolecule biosynthetic process GO:0034645 224 0.178
central nervous system development GO:0007417 387 0.167
cellular nitrogen compound biosynthetic process GO:0044271 218 0.161
head development GO:0060322 303 0.157
ameboidal type cell migration GO:0001667 143 0.147
nucleobase containing compound biosynthetic process GO:0034654 205 0.142
regulation of cell shape GO:0008360 1 0.130
response to fluid shear stress GO:0034405 2 0.126
regulation of rna metabolic process GO:0051252 224 0.126
blood vessel development GO:0001568 246 0.126
eye development GO:0001654 277 0.124
negative regulation of cellular process GO:0048523 283 0.115
aging GO:0007568 2 0.115
sensory organ development GO:0007423 393 0.112
nucleic acid metabolic process GO:0090304 244 0.111
macromolecule biosynthetic process GO:0009059 227 0.109
regulation of gene expression GO:0010468 265 0.108
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.105
positive regulation of biological process GO:0048518 253 0.105
regulation of biosynthetic process GO:0009889 250 0.098
artery development GO:0060840 22 0.098
chordate embryonic development GO:0043009 271 0.095
hemopoiesis GO:0030097 183 0.093
cellular response to external stimulus GO:0071496 2 0.090
regulation of cellular metabolic process GO:0031323 320 0.090
embryonic organ development GO:0048568 381 0.089
regulation of nucleic acid templated transcription GO:1903506 213 0.087
establishment of localization GO:0051234 244 0.087
brain development GO:0007420 293 0.081
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.081
protein localization to nucleus GO:0034504 3 0.080
cellular component morphogenesis GO:0032989 336 0.075
larval development GO:0002164 2 0.073
gene expression GO:0010467 252 0.070
mitotic dna damage checkpoint GO:0044773 4 0.070
cellular biosynthetic process GO:0044249 286 0.069
cell morphogenesis GO:0000902 289 0.068
regulation of metabolic process GO:0019222 359 0.067
response to chemical GO:0042221 320 0.067
cellular response to extracellular stimulus GO:0031668 2 0.065
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.065
retina development in camera type eye GO:0060041 146 0.064
rna biosynthetic process GO:0032774 181 0.063
regulation of protein transport GO:0051223 3 0.060
regulation of cellular biosynthetic process GO:0031326 245 0.060
positive regulation of biosynthetic process GO:0009891 68 0.060
system process GO:0003008 185 0.058
regulation of macromolecule biosynthetic process GO:0010556 225 0.058
regulation of multicellular organismal process GO:0051239 277 0.057
embryo development ending in birth or egg hatching GO:0009792 271 0.057
development of primary female sexual characteristics GO:0046545 4 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.055
signal transduction GO:0007165 455 0.055
protein import into nucleus GO:0006606 3 0.055
enzyme linked receptor protein signaling pathway GO:0007167 106 0.054
female sex differentiation GO:0046660 4 0.053
camera type eye development GO:0043010 222 0.052
mitotic dna integrity checkpoint GO:0044774 4 0.052
cell matrix adhesion GO:0007160 4 0.052
meiotic nuclear division GO:0007126 4 0.052
cognition GO:0050890 1 0.052
heterocycle metabolic process GO:0046483 290 0.051
multi organism process GO:0051704 134 0.051
single organism nuclear import GO:1902593 3 0.051
response to alkaloid GO:0043279 2 0.051
establishment of protein localization to organelle GO:0072594 4 0.051
organic cyclic compound biosynthetic process GO:1901362 223 0.050
organic cyclic compound metabolic process GO:1901360 301 0.050
generation of neurons GO:0048699 385 0.049
vascular endothelial growth factor signaling pathway GO:0038084 3 0.049
cell projection organization GO:0030030 284 0.048
adherens junction organization GO:0034332 4 0.048
transport GO:0006810 220 0.047
response to external stimulus GO:0009605 264 0.047
forebrain development GO:0030900 96 0.047
cellular aromatic compound metabolic process GO:0006725 295 0.046
female gonad development GO:0008585 4 0.046
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.046
single organism metabolic process GO:0044710 217 0.046
morphogenesis of an epithelium GO:0002009 333 0.046
organelle organization GO:0006996 227 0.046
regulation of establishment of protein localization GO:0070201 4 0.046
regulation of metal ion transport GO:0010959 4 0.045
regulation of cytokine production GO:0001817 3 0.045
cell substrate adhesion GO:0031589 4 0.045
organic substance biosynthetic process GO:1901576 289 0.045
nucleocytoplasmic transport GO:0006913 4 0.045
protein targeting to nucleus GO:0044744 3 0.045
peptide transport GO:0015833 1 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.044
hematopoietic or lymphoid organ development GO:0048534 191 0.044
regulation of intracellular protein transport GO:0033157 3 0.044
positive regulation of transport GO:0051050 2 0.043
regulation of protein targeting GO:1903533 2 0.043
g1 s transition of mitotic cell cycle GO:0000082 1 0.043
aromatic compound biosynthetic process GO:0019438 217 0.043
cellular response to nutrient levels GO:0031669 2 0.043
regulation of cell communication GO:0010646 232 0.043
post embryonic organ development GO:0048569 4 0.043
protein metabolic process GO:0019538 183 0.043
regulation of production of molecular mediator of immune response GO:0002700 1 0.042
regionalization GO:0003002 274 0.042
response to organic substance GO:0010033 153 0.041
regulation of protein import into nucleus GO:0042306 2 0.041
regulation of protein localization to nucleus GO:1900180 2 0.040
angiogenesis GO:0001525 158 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.040
somitogenesis GO:0001756 87 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.039
cartilage condensation GO:0001502 3 0.039
regulation of response to stimulus GO:0048583 269 0.038
regulation of epithelial cell proliferation GO:0050678 3 0.038
transcription from rna polymerase ii promoter GO:0006366 80 0.038
nuclear import GO:0051170 3 0.038
blood vessel morphogenesis GO:0048514 216 0.038
nitric oxide metabolic process GO:0046209 2 0.038
embryonic organ morphogenesis GO:0048562 274 0.038
regulation of nucleocytoplasmic transport GO:0046822 2 0.038
rna metabolic process GO:0016070 219 0.037
single organism organelle organization GO:1902589 199 0.037
kidney development GO:0001822 92 0.036
cell surface receptor signaling pathway GO:0007166 325 0.036
positive regulation of stem cell proliferation GO:2000648 1 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.036
response to ketone GO:1901654 1 0.036
immune system process GO:0002376 241 0.036
regulation of filopodium assembly GO:0051489 2 0.036
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
cell migration involved in gastrulation GO:0042074 79 0.035
regulation of dna replication GO:0006275 3 0.035
regulation of biological quality GO:0065008 263 0.034
response to drug GO:0042493 3 0.034
negative regulation of programmed cell death GO:0043069 58 0.034
actin filament based process GO:0030029 64 0.034
mitochondrion organization GO:0007005 4 0.034
regulation of synaptic plasticity GO:0048167 1 0.034
protein import GO:0017038 3 0.034
nitric oxide biosynthetic process GO:0006809 2 0.033
bmp signaling pathway GO:0030509 52 0.033
response to stress GO:0006950 263 0.033
apoptotic process GO:0006915 116 0.032
b cell activation GO:0042113 2 0.032
synaptic target recognition GO:0008039 1 0.032
renal system development GO:0072001 94 0.032
biosynthetic process GO:0009058 294 0.032
regulation of primary metabolic process GO:0080090 311 0.032
venous blood vessel development GO:0060841 9 0.032
lipid storage GO:0019915 1 0.031
positive regulation of epithelial cell migration GO:0010634 2 0.031
endocrine system development GO:0035270 65 0.031
extrinsic apoptotic signaling pathway GO:0097191 3 0.031
nuclear transport GO:0051169 4 0.031
cellular component biogenesis GO:0044085 178 0.031
reactive oxygen species biosynthetic process GO:1903409 1 0.031
negative regulation of immune response GO:0050777 2 0.031
immune system development GO:0002520 191 0.031
regulation of cell projection assembly GO:0060491 4 0.031
tube morphogenesis GO:0035239 349 0.031
negative regulation of striated muscle tissue development GO:0045843 2 0.031
regulation of muscle contraction GO:0006937 3 0.031
regulation of skeletal muscle fiber development GO:0048742 2 0.031
positive regulation of neuron death GO:1901216 1 0.031
protein complex subunit organization GO:0071822 46 0.030
cellular protein modification process GO:0006464 100 0.030
response to abiotic stimulus GO:0009628 122 0.030
response to external biotic stimulus GO:0043207 97 0.030
astrocyte differentiation GO:0048708 1 0.030
regulation of transcription dna templated GO:0006355 213 0.029
cell substrate junction assembly GO:0007044 2 0.029
urogenital system development GO:0001655 97 0.029
cell cycle g2 m phase transition GO:0044839 4 0.029
regulation of cardiac muscle tissue development GO:0055024 1 0.029
regulation of ion transmembrane transporter activity GO:0032412 2 0.029
transcription dna templated GO:0006351 181 0.029
sensory organ morphogenesis GO:0090596 200 0.029
phagocytosis GO:0006909 3 0.029
axon development GO:0061564 166 0.029
inositol lipid mediated signaling GO:0048017 2 0.029
pronephros development GO:0048793 69 0.029
heterocycle biosynthetic process GO:0018130 215 0.029
response to vitamin GO:0033273 3 0.028
macromolecular complex subunit organization GO:0043933 74 0.028
regulation of blood circulation GO:1903522 32 0.028
phosphorus metabolic process GO:0006793 109 0.028
cellular response to starvation GO:0009267 1 0.028
multicellular organismal homeostasis GO:0048871 29 0.028
stem cell proliferation GO:0072089 4 0.028
reactive nitrogen species metabolic process GO:2001057 0 0.028
meiotic cell cycle process GO:1903046 3 0.028
death GO:0016265 121 0.028
heart contraction GO:0060047 71 0.028
embryonic skeletal system development GO:0048706 97 0.027
regulation of mesenchymal cell proliferation GO:0010464 1 0.027
axonogenesis GO:0007409 152 0.027
positive regulation of cellular process GO:0048522 201 0.027
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.027
gastrulation GO:0007369 208 0.027
meiotic chromosome segregation GO:0045132 3 0.027
regulation of transmembrane transporter activity GO:0022898 2 0.026
digestive tract development GO:0048565 265 0.026
positive regulation of cell death GO:0010942 29 0.026
gland development GO:0048732 143 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.026
cell growth GO:0016049 57 0.026
vasculature development GO:0001944 278 0.026
tissue migration GO:0090130 37 0.026
regulation of vasculature development GO:1901342 33 0.026
production of molecular mediator of immune response GO:0002440 2 0.026
hormone secretion GO:0046879 2 0.026
cellular component assembly involved in morphogenesis GO:0010927 107 0.026
hypothalamus cell differentiation GO:0021979 4 0.025
double strand break repair GO:0006302 3 0.025
cell part morphogenesis GO:0032990 246 0.025
skeletal system development GO:0001501 181 0.025
mesenchyme development GO:0060485 127 0.025
response to organic cyclic compound GO:0014070 51 0.025
maintenance of location GO:0051235 4 0.025
cardiac atrium development GO:0003230 4 0.025
nucleic acid templated transcription GO:0097659 181 0.025
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.025
spinal cord development GO:0021510 46 0.024
regulation of calcium ion transport GO:0051924 2 0.024
mesenchymal cell proliferation GO:0010463 1 0.024
cellular protein metabolic process GO:0044267 129 0.024
chemosensory behavior GO:0007635 1 0.024
telomere organization GO:0032200 1 0.024
regulation of binding GO:0051098 3 0.024
neuron development GO:0048666 262 0.024
regulation of stem cell differentiation GO:2000736 4 0.024
chemical homeostasis GO:0048878 49 0.024
response to other organism GO:0051707 97 0.024
regulation of cell matrix adhesion GO:0001952 1 0.024
single organism transport GO:0044765 206 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
regulation of transporter activity GO:0032409 2 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.024
growth GO:0040007 174 0.023
embryonic skeletal system morphogenesis GO:0048704 93 0.023
single organism membrane fusion GO:0044801 2 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
cell projection assembly GO:0030031 64 0.023
g2 m transition of mitotic cell cycle GO:0000086 4 0.023
ion homeostasis GO:0050801 41 0.023
positive regulation of cell adhesion GO:0045785 1 0.023
muscle cell development GO:0055001 115 0.023
vasculogenesis GO:0001570 41 0.023
amine metabolic process GO:0009308 2 0.023
response to hexose GO:0009746 3 0.023
neuron projection development GO:0031175 180 0.022
multicellular organismal metabolic process GO:0044236 2 0.022
camera type eye morphogenesis GO:0048593 108 0.022
negative regulation of multicellular organismal process GO:0051241 69 0.022
somatic muscle development GO:0007525 4 0.022
antimicrobial humoral response GO:0019730 2 0.022
circulatory system process GO:0003013 87 0.022
kidney vasculature development GO:0061440 2 0.022
locomotion GO:0040011 313 0.022
regulation of heart growth GO:0060420 2 0.022
branchiomotor neuron axon guidance GO:0021785 1 0.022
i kappab kinase nf kappab signaling GO:0007249 4 0.022
regulation of cell development GO:0060284 100 0.022
cardiac atrium morphogenesis GO:0003209 2 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
embryonic digestive tract development GO:0048566 4 0.022
cellular carbohydrate metabolic process GO:0044262 4 0.022
glomerulus vasculature development GO:0072012 2 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
regulation of apoptotic process GO:0042981 98 0.021
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.021
negative regulation of cellular catabolic process GO:0031330 3 0.021
neural retina development GO:0003407 49 0.021
connective tissue development GO:0061448 99 0.021
hepaticobiliary system development GO:0061008 98 0.021
lateral line system development GO:0048925 76 0.021
macromolecule modification GO:0043412 111 0.021
positive chemotaxis GO:0050918 5 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
response to carbohydrate GO:0009743 3 0.021
developmental cell growth GO:0048588 52 0.021
negative regulation of catabolic process GO:0009895 3 0.021
regulation of glial cell differentiation GO:0045685 4 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
response to biotic stimulus GO:0009607 97 0.020
cellular response to growth factor stimulus GO:0071363 39 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
striated muscle cell differentiation GO:0051146 129 0.020
negative regulation of muscle tissue development GO:1901862 2 0.020
ovarian follicle development GO:0001541 2 0.020
ventricular cardiac muscle tissue development GO:0003229 3 0.020
negative regulation of rna biosynthetic process GO:1902679 45 0.020
protein modification process GO:0036211 100 0.020
positive regulation of response to stimulus GO:0048584 80 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
regulation of cellular component organization GO:0051128 86 0.020
pathway restricted smad protein phosphorylation GO:0060389 1 0.020
negative regulation of cytokine production GO:0001818 1 0.020
epithelium migration GO:0090132 25 0.020
ovulation cycle GO:0042698 2 0.020
protein secretion GO:0009306 1 0.019
circadian sleep wake cycle sleep GO:0050802 1 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
regulation of reproductive process GO:2000241 4 0.019
embryonic cranial skeleton morphogenesis GO:0048701 90 0.019
regulation of behavior GO:0050795 24 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
digestive tract morphogenesis GO:0048546 231 0.019
regulation of bmp signaling pathway GO:0030510 39 0.019
notochord development GO:0030903 54 0.019
ovulation cycle process GO:0022602 2 0.019
phosphorylation GO:0016310 69 0.019
programmed cell death GO:0012501 119 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
eye morphogenesis GO:0048592 144 0.019
b cell differentiation GO:0030183 1 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
cardiac cell fate commitment GO:0060911 1 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
membrane fusion GO:0061025 2 0.019
transmembrane transport GO:0055085 120 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
fin development GO:0033333 77 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
circadian sleep wake cycle GO:0042745 2 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
negative regulation of biological process GO:0048519 304 0.018
glomerulus development GO:0032835 27 0.018
autophagy GO:0006914 4 0.018
g protein coupled receptor signaling pathway GO:0007186 74 0.018
cell junction organization GO:0034330 11 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
negative regulation of dna metabolic process GO:0051053 4 0.018
positive regulation of cytokine production GO:0001819 2 0.018
stem cell division GO:0017145 1 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
odontogenesis of dentin containing tooth GO:0042475 1 0.018
regulation of signal transduction GO:0009966 225 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
response to nutrient GO:0007584 3 0.018
regulation of organ growth GO:0046620 3 0.018
dna catabolic process GO:0006308 1 0.018
regulation of epithelial to mesenchymal transition GO:0010717 3 0.017
oocyte maturation GO:0001556 4 0.017
cellular amine metabolic process GO:0044106 2 0.017
cell projection morphogenesis GO:0048858 244 0.017
cell proliferation GO:0008283 80 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.017
regulation of signaling GO:0023051 235 0.017
biological adhesion GO:0022610 40 0.017
negative regulation of cell death GO:0060548 60 0.017
septum transversum development GO:0003343 4 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
multicellular organism growth GO:0035264 4 0.017
negative regulation of map kinase activity GO:0043407 2 0.017
mesenchymal cell differentiation GO:0048762 87 0.017
mitotic cell cycle process GO:1903047 48 0.017
telomere maintenance GO:0000723 1 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
regulation of circadian sleep wake cycle GO:0042749 1 0.017
negative regulation of signaling GO:0023057 96 0.017
digestive system development GO:0055123 289 0.017
regulation of circadian rhythm GO:0042752 4 0.017
regulation of endothelial cell proliferation GO:0001936 1 0.017
signal transduction in absence of ligand GO:0038034 1 0.017
convergent extension GO:0060026 118 0.017
cranial suture morphogenesis GO:0060363 1 0.017
regulation of tube size GO:0035150 2 0.017
wnt signaling pathway GO:0016055 80 0.017
hematopoietic stem cell differentiation GO:0060218 20 0.017
mesenchymal cell development GO:0014031 78 0.016
regulation of synapse assembly GO:0051963 3 0.016
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.016
central nervous system neuron differentiation GO:0021953 74 0.016
gland morphogenesis GO:0022612 13 0.016
cellular component movement GO:0006928 335 0.016
muscle tissue development GO:0060537 110 0.016
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.016
adherens junction assembly GO:0034333 1 0.016
adult behavior GO:0030534 2 0.016
sprouting angiogenesis GO:0002040 53 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
cardiac chamber formation GO:0003207 4 0.016
meiosis i GO:0007127 1 0.016
blood vessel endothelial cell migration GO:0043534 18 0.016
gtp catabolic process GO:0006184 2 0.016
negative regulation of secretion by cell GO:1903531 2 0.016
osteoclast differentiation GO:0030316 1 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.016
regulation of cell differentiation GO:0045595 142 0.016
anterior posterior pattern specification GO:0009952 152 0.016
negative regulation of dna replication GO:0008156 2 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
inner ear development GO:0048839 126 0.016
sensory perception of smell GO:0007608 2 0.016
cranial nerve development GO:0021545 42 0.016
striated muscle tissue development GO:0014706 110 0.016
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of protein complex assembly GO:0043254 3 0.015
actin cytoskeleton organization GO:0030036 63 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
calcium ion homeostasis GO:0055074 19 0.015
myeloid leukocyte migration GO:0097529 12 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
exocrine system development GO:0035272 28 0.015
cell motility GO:0048870 244 0.015
canonical wnt signaling pathway GO:0060070 48 0.015
positive regulation of neuron apoptotic process GO:0043525 1 0.015
cell aging GO:0007569 2 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
peptidyl serine modification GO:0018209 2 0.015
response to monosaccharide GO:0034284 3 0.015
amino acid transport GO:0006865 2 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
embryonic heart tube development GO:0035050 133 0.015
nerve development GO:0021675 45 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
regulation of sodium ion transport GO:0002028 2 0.015
regulation of blood vessel size GO:0050880 2 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
positive regulation of metabolic process GO:0009893 108 0.015
regulation of angiogenesis GO:0045765 26 0.015
regulation of heart contraction GO:0008016 32 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
stem cell maintenance GO:0019827 4 0.015
chemotaxis GO:0006935 104 0.014
immune response GO:0006955 28 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
cellular response to stress GO:0033554 62 0.014
muscle structure development GO:0061061 196 0.014
negative regulation of chemotaxis GO:0050922 4 0.014
regulation of synapse organization GO:0050807 3 0.014
smooth muscle contraction GO:0006939 2 0.014
heart process GO:0003015 71 0.014
lymph vessel development GO:0001945 27 0.014
nephron morphogenesis GO:0072028 2 0.014
negative regulation of secretion GO:0051048 2 0.014
blood circulation GO:0008015 87 0.014
inorganic ion transmembrane transport GO:0098660 57 0.014
glial cell migration GO:0008347 3 0.014
double strand break repair via homologous recombination GO:0000724 1 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
intracellular signal transduction GO:0035556 85 0.014
protein homooligomerization GO:0051260 3 0.014
epithelial to mesenchymal transition GO:0001837 21 0.014
actomyosin structure organization GO:0031032 53 0.014
embryonic hemopoiesis GO:0035162 53 0.014
epithelial cell differentiation GO:0030855 116 0.014
pectoral fin development GO:0033339 50 0.014
hormone transport GO:0009914 2 0.014
cation transmembrane transport GO:0098655 65 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
somite development GO:0061053 96 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
myeloid cell development GO:0061515 32 0.014
positive regulation of cell cycle GO:0045787 3 0.014
lymphangiogenesis GO:0001946 25 0.014
cellular component disassembly GO:0022411 1 0.014
specification of symmetry GO:0009799 204 0.014
epithelial cell migration GO:0010631 25 0.013
cell fate commitment GO:0045165 99 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
larval heart development GO:0007508 2 0.013
response to steroid hormone GO:0048545 35 0.013
cytoskeleton organization GO:0007010 96 0.013
regulation of developmental process GO:0050793 247 0.013
mononuclear cell proliferation GO:0032943 1 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
renal system vasculature development GO:0061437 2 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
atrioventricular valve development GO:0003171 11 0.013
diencephalon development GO:0021536 58 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
lipid homeostasis GO:0055088 3 0.013

ptpn21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
myopathy DOID:423 0 0.045
muscular disease DOID:0080000 0 0.045
musculoskeletal system disease DOID:17 0 0.045
muscle tissue disease DOID:66 0 0.045
heart disease DOID:114 0 0.020
cardiomyopathy DOID:0050700 0 0.020
intrinsic cardiomyopathy DOID:0060036 0 0.020
cardiovascular system disease DOID:1287 0 0.020
disease of cellular proliferation DOID:14566 0 0.019