Danio rerio

13 known processes

wdr18

WD repeat domain 18

(Aliases: wu:fa16f06,zgc:92370,wu:fb79d07)

wdr18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance biosynthetic process GO:1901576 289 0.346
Yeast
cellular macromolecule metabolic process GO:0044260 391 0.324
Yeast
mitotic dna integrity checkpoint GO:0044774 4 0.304
regulation of cellular metabolic process GO:0031323 320 0.284
Yeast
regulation of gene expression GO:0010468 265 0.281
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.259
Yeast
nucleic acid metabolic process GO:0090304 244 0.244
Yeast
nucleobase containing compound biosynthetic process GO:0034654 205 0.222
regulation of primary metabolic process GO:0080090 311 0.215
Yeast
regulation of metabolic process GO:0019222 359 0.215
Yeast
cellular aromatic compound metabolic process GO:0006725 295 0.212
Yeast
cellular macromolecule biosynthetic process GO:0034645 224 0.194
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.192
Yeast
regulation of nucleic acid templated transcription GO:1903506 213 0.174
nucleobase containing compound metabolic process GO:0006139 274 0.162
Yeast
nitrogen compound metabolic process GO:0006807 319 0.154
Yeast
larval development GO:0002164 2 0.151
regulation of macromolecule biosynthetic process GO:0010556 225 0.144
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.141
Yeast
cellular biosynthetic process GO:0044249 286 0.132
Yeast
regulation of rna metabolic process GO:0051252 224 0.129
gene expression GO:0010467 252 0.124
Yeast
organic cyclic compound metabolic process GO:1901360 301 0.120
Yeast
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.120
heterocycle metabolic process GO:0046483 290 0.119
Yeast
macromolecule biosynthetic process GO:0009059 227 0.102
Yeast
regulation of cellular biosynthetic process GO:0031326 245 0.102
Yeast
nucleic acid templated transcription GO:0097659 181 0.096
aromatic compound biosynthetic process GO:0019438 217 0.090
regulation of biosynthetic process GO:0009889 250 0.089
Yeast
cellular nitrogen compound biosynthetic process GO:0044271 218 0.088
regulation of transcription dna templated GO:0006355 213 0.088
regulation of macromolecule metabolic process GO:0060255 317 0.084
Yeast
transcription dna templated GO:0006351 181 0.084
cognition GO:0050890 1 0.081
cellular nitrogen compound metabolic process GO:0034641 290 0.080
Yeast
aging GO:0007568 2 0.076
cell projection morphogenesis GO:0048858 244 0.073
determination of bilateral symmetry GO:0009855 204 0.073
cellular carbohydrate metabolic process GO:0044262 4 0.072
mitotic dna damage checkpoint GO:0044773 4 0.069
regulation of cell death GO:0010941 103 0.068
biosynthetic process GO:0009058 294 0.067
Yeast
heterocycle biosynthetic process GO:0018130 215 0.065
response to stress GO:0006950 263 0.064
organic cyclic compound biosynthetic process GO:1901362 223 0.064
cell morphogenesis involved in differentiation GO:0000904 195 0.064
regulation of programmed cell death GO:0043067 101 0.062
regulation of rna biosynthetic process GO:2001141 213 0.061
digestive system development GO:0055123 289 0.060
positive regulation of catabolic process GO:0009896 4 0.060
rna biosynthetic process GO:0032774 181 0.059
nucleocytoplasmic transport GO:0006913 4 0.059
cellular response to extracellular stimulus GO:0031668 2 0.059
signal transduction GO:0007165 455 0.058
rna metabolic process GO:0016070 219 0.055
Yeast
protein import into nucleus GO:0006606 3 0.054
regulation of cell cycle GO:0051726 52 0.053
protein metabolic process GO:0019538 183 0.053
regulation of establishment of protein localization GO:0070201 4 0.052
regulation of apoptotic process GO:0042981 98 0.052
modification dependent macromolecule catabolic process GO:0043632 3 0.051
positive regulation of cellular catabolic process GO:0031331 3 0.049
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.048
establishment of protein localization to organelle GO:0072594 4 0.048
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.048
meiotic nuclear division GO:0007126 4 0.047
negative regulation of biological process GO:0048519 304 0.047
death GO:0016265 121 0.045
single organism metabolic process GO:0044710 217 0.044
Yeast
macromolecule modification GO:0043412 111 0.044
cell surface receptor signaling pathway GO:0007166 325 0.044
nuclear transport GO:0051169 4 0.044
cell part morphogenesis GO:0032990 246 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.043
digestive tract morphogenesis GO:0048546 231 0.042
mrna transport GO:0051028 2 0.041
cell morphogenesis GO:0000902 289 0.041
regulation of protein catabolic process GO:0042176 1 0.039
modification dependent protein catabolic process GO:0019941 3 0.039
protein acylation GO:0043543 3 0.039
multi organism cellular process GO:0044764 2 0.039
maintenance of location GO:0051235 4 0.038
regulation of gtp catabolic process GO:0033124 2 0.037
tube morphogenesis GO:0035239 349 0.037
response to carbohydrate GO:0009743 3 0.037
regulation of dna recombination GO:0000018 2 0.037
protein localization to nucleus GO:0034504 3 0.037
response to nutrient GO:0007584 3 0.036
digestive tract development GO:0048565 265 0.035
negative regulation of cellular process GO:0048523 283 0.034
regulation of histone methylation GO:0031060 3 0.034
ubiquitin dependent protein catabolic process GO:0006511 3 0.033
cell growth GO:0016049 57 0.033
regulation of cell communication GO:0010646 232 0.032
muscle organ development GO:0007517 101 0.031
mitotic cell cycle GO:0000278 64 0.031
regulation of response to stimulus GO:0048583 269 0.031
protein targeting to nucleus GO:0044744 3 0.030
regulation of protein targeting GO:1903533 2 0.030
transcription from rna polymerase ii promoter GO:0006366 80 0.029
regulation of signal transduction GO:0009966 225 0.029
cellular protein modification process GO:0006464 100 0.029
cellular protein metabolic process GO:0044267 129 0.029
astrocyte differentiation GO:0048708 1 0.029
organelle organization GO:0006996 227 0.028
Yeast
peptidyl lysine acetylation GO:0018394 2 0.028
regulation of cell differentiation GO:0045595 142 0.028
positive regulation of cellular biosynthetic process GO:0031328 68 0.028
cell projection organization GO:0030030 284 0.028
response to organic substance GO:0010033 153 0.027
nuclear import GO:0051170 3 0.027
cellular catabolic process GO:0044248 27 0.027
protein import GO:0017038 3 0.027
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.026
protein acetylation GO:0006473 2 0.026
sister chromatid cohesion GO:0007062 2 0.026
histone h3 k4 methylation GO:0051568 2 0.026
chordate embryonic development GO:0043009 271 0.026
rna modification GO:0009451 2 0.026
peptidyl lysine trimethylation GO:0018023 1 0.025
nuclear export GO:0051168 1 0.025
lipid storage GO:0019915 1 0.025
neuron projection morphogenesis GO:0048812 161 0.025
regulation of signal transduction by p53 class mediator GO:1901796 9 0.025
negative regulation of nucleic acid templated transcription GO:1903507 45 0.025
positive regulation of cell cycle GO:0045787 3 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
positive regulation of dna metabolic process GO:0051054 1 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
regulation of glial cell differentiation GO:0045685 4 0.023
macromolecule methylation GO:0043414 19 0.023
developmental growth involved in morphogenesis GO:0060560 86 0.023
protein modification process GO:0036211 100 0.022
oxoacid metabolic process GO:0043436 31 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
positive regulation of carbohydrate metabolic process GO:0045913 1 0.022
positive regulation of rna metabolic process GO:0051254 59 0.022
developmental cell growth GO:0048588 52 0.022
positive regulation of biosynthetic process GO:0009891 68 0.022
regulation of protein transport GO:0051223 3 0.022
neuron differentiation GO:0030182 353 0.022
negative regulation of cell death GO:0060548 60 0.022
gtp metabolic process GO:0046039 4 0.021
organic acid metabolic process GO:0006082 31 0.021
b cell differentiation GO:0030183 1 0.021
camera type eye development GO:0043010 222 0.021
apoptotic process GO:0006915 116 0.021
specification of symmetry GO:0009799 204 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
internal protein amino acid acetylation GO:0006475 2 0.021
cellular component morphogenesis GO:0032989 336 0.021
positive regulation of dna templated transcription elongation GO:0032786 1 0.021
response to chemical GO:0042221 320 0.020
negative regulation of cellular biosynthetic process GO:0031327 55 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
axonogenesis GO:0007409 152 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
negative regulation of gene expression GO:0010629 65 0.020
regulation of dna replication GO:0006275 3 0.020
Yeast
eye development GO:0001654 277 0.019
mitotic g2 m transition checkpoint GO:0044818 3 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
neuron development GO:0048666 262 0.019
cell death GO:0008219 121 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
immune system process GO:0002376 241 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
response to monosaccharide GO:0034284 3 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
cellular response to organic substance GO:0071310 105 0.018
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.018
zymogen activation GO:0031638 3 0.018
b cell activation GO:0042113 2 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
developmental growth GO:0048589 166 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
viral process GO:0016032 1 0.018
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.018
histone lysine methylation GO:0034968 12 0.018
gtp catabolic process GO:0006184 2 0.018
positive regulation of biological process GO:0048518 253 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
cellular response to nutrient levels GO:0031669 2 0.017
positive regulation of transport GO:0051050 2 0.017
cellular response to external stimulus GO:0071496 2 0.017
cellular protein catabolic process GO:0044257 4 0.017
organic substance catabolic process GO:1901575 28 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
small molecule metabolic process GO:0044281 77 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
regulation of mitotic cell cycle GO:0007346 25 0.016
multicellular organism growth GO:0035264 4 0.016
single organism nuclear import GO:1902593 3 0.016
mitochondrion organization GO:0007005 4 0.016
response to glucose GO:0009749 3 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
nucleobase containing compound transport GO:0015931 2 0.016
positive regulation of cellular process GO:0048522 201 0.016
carbohydrate homeostasis GO:0033500 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
generation of neurons GO:0048699 385 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.015
double strand break repair GO:0006302 3 0.015
liver development GO:0001889 96 0.015
positive regulation of nucleic acid templated transcription GO:1903508 57 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
single organism organelle organization GO:1902589 199 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
chemosensory behavior GO:0007635 1 0.015
programmed cell death GO:0012501 119 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
negative regulation of secretion by cell GO:1903531 2 0.015
central nervous system development GO:0007417 387 0.014
regionalization GO:0003002 274 0.014
proteolysis GO:0006508 38 0.014
mrna export from nucleus GO:0006406 1 0.014
meiotic chromosome segregation GO:0045132 3 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
response to hexose GO:0009746 3 0.014
regulation of cytokine production GO:0001817 3 0.014
negative regulation of myeloid cell differentiation GO:0045638 1 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
negative regulation of cell communication GO:0010648 96 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
cellular ketone metabolic process GO:0042180 11 0.013
cellular macromolecule catabolic process GO:0044265 12 0.013
skeletal muscle organ development GO:0060538 78 0.013
regulation of gtpase activity GO:0043087 2 0.013
cellular response to dna damage stimulus GO:0006974 24 0.013
single organism biosynthetic process GO:0044711 71 0.013
Yeast
meiotic cell cycle process GO:1903046 3 0.013
response to temperature stimulus GO:0009266 15 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
rna export from nucleus GO:0006405 1 0.013
signal transduction by p53 class mediator GO:0072331 13 0.013
autophagy GO:0006914 4 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
double strand break repair via homologous recombination GO:0000724 1 0.013
establishment of localization GO:0051234 244 0.012
regulation of biological quality GO:0065008 263 0.012
peptidyl lysine methylation GO:0018022 3 0.012
intracellular signal transduction GO:0035556 85 0.012
chromosome organization involved in meiosis GO:0070192 1 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
axon development GO:0061564 166 0.012
skeletal muscle tissue development GO:0007519 67 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
sensory organ development GO:0007423 393 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
single organism transport GO:0044765 206 0.012
lateral inhibition GO:0046331 1 0.012
embryonic organ development GO:0048568 381 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
protein secretion GO:0009306 1 0.012
regulation of molecular function GO:0065009 70 0.012
phagocytosis GO:0006909 3 0.012
covalent chromatin modification GO:0016569 20 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
hepaticobiliary system development GO:0061008 98 0.012
adult behavior GO:0030534 2 0.012
organic substance transport GO:0071702 58 0.011
regulation of signaling GO:0023051 235 0.011
rna transport GO:0050658 2 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
single organism localization GO:1902578 225 0.011
macromolecule localization GO:0033036 54 0.011
negative regulation of signal transduction GO:0009968 94 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
positive regulation of muscle tissue development GO:1901863 1 0.011
establishment of rna localization GO:0051236 3 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
meiosis i GO:0007127 1 0.011
negative regulation of protein transport GO:0051224 3 0.011
cell proliferation GO:0008283 80 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
convergent extension involved in gastrulation GO:0060027 71 0.010
positive regulation of striated muscle tissue development GO:0045844 1 0.010
mitotic g2 dna damage checkpoint GO:0007095 3 0.010
organic cyclic compound catabolic process GO:1901361 15 0.010
dna integrity checkpoint GO:0031570 6 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
negative regulation of mitotic cell cycle GO:0045930 11 0.010
regulation of response to stress GO:0080134 36 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
negative regulation of metabolic process GO:0009892 86 0.010
negative regulation of cytokine production GO:0001818 1 0.010
gene silencing GO:0016458 4 0.010
transport GO:0006810 220 0.010

wdr18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org