Danio rerio

0 known processes

sox8

SRY-box containing gene 8

(Aliases: zgc:109880,MGC109880)

sox8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle tissue development GO:0014706 110 0.524
Mouse
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.453
response to abiotic stimulus GO:0009628 122 0.438
muscle cell development GO:0055001 115 0.390
Mouse
organelle assembly GO:0070925 110 0.380
aromatic compound biosynthetic process GO:0019438 217 0.351
Human Zebrafish Mouse
regulation of circadian sleep wake cycle GO:0042749 1 0.338
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.303
Human Zebrafish Mouse
generation of neurons GO:0048699 385 0.300
Zebrafish Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.285
Human Zebrafish Mouse
sleep GO:0030431 1 0.282
regulation of gene expression GO:0010468 265 0.275
Human Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.270
Human Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.256
Human Zebrafish Mouse
circadian sleep wake cycle process GO:0022410 2 0.248
cellular component movement GO:0006928 335 0.242
Zebrafish Mouse
heterocycle metabolic process GO:0046483 290 0.241
Human Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.227
Human Zebrafish Mouse
muscle tissue development GO:0060537 110 0.223
Mouse
circadian sleep wake cycle GO:0042745 2 0.215
striated muscle cell development GO:0055002 108 0.212
Mouse
cell projection organization GO:0030030 284 0.208
cellular protein catabolic process GO:0044257 4 0.200
cellular component assembly GO:0022607 170 0.189
striated muscle cell differentiation GO:0051146 129 0.179
Mouse
cellular biosynthetic process GO:0044249 286 0.176
Human Zebrafish Mouse
sensory organ development GO:0007423 393 0.171
Zebrafish Mouse
aging GO:0007568 2 0.166
regulation of metabolic process GO:0019222 359 0.161
Human Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.161
Human Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.158
Human Zebrafish Mouse
adult behavior GO:0030534 2 0.157
system process GO:0003008 185 0.156
response to light stimulus GO:0009416 46 0.152
cellular macromolecule biosynthetic process GO:0034645 224 0.148
Human Zebrafish Mouse
modification dependent protein catabolic process GO:0019941 3 0.145
multi organism process GO:0051704 134 0.140
Mouse
larval development GO:0002164 2 0.140
positive regulation of biological process GO:0048518 253 0.139
Human Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.135
Human Zebrafish Mouse
central nervous system development GO:0007417 387 0.133
Zebrafish Mouse
response to external stimulus GO:0009605 264 0.130
positive regulation of cell cycle GO:0045787 3 0.130
neuron development GO:0048666 262 0.127
Zebrafish
gene expression GO:0010467 252 0.125
Human Zebrafish Mouse
eye development GO:0001654 277 0.123
Zebrafish Mouse
single organism organelle organization GO:1902589 199 0.122
regulation of cellular biosynthetic process GO:0031326 245 0.115
Human Zebrafish Mouse
cell part morphogenesis GO:0032990 246 0.108
modification dependent macromolecule catabolic process GO:0043632 3 0.107
positive regulation of rna metabolic process GO:0051254 59 0.106
Human Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.105
Human Zebrafish Mouse
regionalization GO:0003002 274 0.101
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.093
muscle cell differentiation GO:0042692 139 0.093
Mouse
neuromuscular synaptic transmission GO:0007274 2 0.091
response to wounding GO:0009611 116 0.090
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.088
Human Zebrafish Mouse
negative regulation of metabolic process GO:0009892 86 0.087
Mouse
transmission of nerve impulse GO:0019226 19 0.087
brain development GO:0007420 293 0.085
regulation of multicellular organismal process GO:0051239 277 0.085
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.084
Human Zebrafish Mouse
regulation of biological quality GO:0065008 263 0.079
Mouse
muscle structure development GO:0061061 196 0.077
Mouse
neuron projection guidance GO:0097485 86 0.077
organic cyclic compound biosynthetic process GO:1901362 223 0.076
Human Zebrafish Mouse
regulation of signaling GO:0023051 235 0.071
skeletal muscle organ development GO:0060538 78 0.070
Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.069
chordate embryonic development GO:0043009 271 0.068
Mouse
regulation of circadian rhythm GO:0042752 4 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.067
Human Zebrafish Mouse
chemotaxis GO:0006935 104 0.065
rna biosynthetic process GO:0032774 181 0.063
Human Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.062
Human Mouse
locomotory behavior GO:0007626 34 0.058
response to chemical GO:0042221 320 0.058
cellular response to external stimulus GO:0071496 2 0.057
single organism behavior GO:0044708 24 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
regulation of synapse organization GO:0050807 3 0.055
centrosome cycle GO:0007098 1 0.055
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.055
negative regulation of histone methylation GO:0031061 1 0.054
eye morphogenesis GO:0048592 144 0.054
Zebrafish Mouse
regulation of mrna processing GO:0050684 3 0.053
anterior posterior pattern specification GO:0009952 152 0.052
positive regulation of transport GO:0051050 2 0.052
organic substance biosynthetic process GO:1901576 289 0.051
Human Zebrafish Mouse
protein import GO:0017038 3 0.050
regulation of transcription dna templated GO:0006355 213 0.049
Human Zebrafish Mouse
dorsal ventral pattern formation GO:0009953 125 0.049
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.049
Zebrafish
single organism localization GO:1902578 225 0.049
multi organism reproductive process GO:0044703 36 0.048
Mouse
regulation of organ growth GO:0046620 3 0.048
regulation of oocyte development GO:0060281 3 0.047
transcription from rna polymerase ii promoter GO:0006366 80 0.047
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.046
Human Zebrafish Mouse
positive regulation of muscle organ development GO:0048636 1 0.046
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.045
Human Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.044
Human Zebrafish Mouse
immune system process GO:0002376 241 0.044
regulation of hormone secretion GO:0046883 2 0.043
regulation of macromolecule biosynthetic process GO:0010556 225 0.043
Human Zebrafish Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.043
Mouse
meiotic nuclear division GO:0007126 4 0.042
cellular aromatic compound metabolic process GO:0006725 295 0.042
Human Zebrafish Mouse
immune system development GO:0002520 191 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.041
axon guidance GO:0007411 86 0.041
regulation of transmembrane transporter activity GO:0022898 2 0.041
regulation of response to stimulus GO:0048583 269 0.041
entrainment of circadian clock GO:0009649 2 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
Human Zebrafish Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.040
muscle fiber development GO:0048747 52 0.040
Mouse
tissue regeneration GO:0042246 74 0.040
Zebrafish
biosynthetic process GO:0009058 294 0.039
Human Zebrafish Mouse
transcription dna templated GO:0006351 181 0.038
Human Zebrafish Mouse
regulation of mrna splicing via spliceosome GO:0048024 3 0.037
regulation of embryonic development GO:0045995 47 0.037
Zebrafish
response to stress GO:0006950 263 0.037
Zebrafish
camera type eye development GO:0043010 222 0.037
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.036
Zebrafish Mouse
lipid storage GO:0019915 1 0.036
multicellular organism growth GO:0035264 4 0.036
regulation of rna metabolic process GO:0051252 224 0.035
Human Zebrafish Mouse
positive regulation of metabolic process GO:0009893 108 0.035
Human Zebrafish Mouse
neuron projection morphogenesis GO:0048812 161 0.035
protein metabolic process GO:0019538 183 0.034
oocyte maturation GO:0001556 4 0.034
segmentation GO:0035282 97 0.034
cellular nitrogen compound biosynthetic process GO:0044271 218 0.034
Human Zebrafish Mouse
smooth muscle tissue development GO:0048745 1 0.033
cellular protein modification process GO:0006464 100 0.033
regulation of cell death GO:0010941 103 0.032
Mouse
circadian sleep wake cycle sleep GO:0050802 1 0.032
retina development in camera type eye GO:0060041 146 0.032
Zebrafish Mouse
multicellular organismal water homeostasis GO:0050891 1 0.032
sprouting angiogenesis GO:0002040 53 0.032
response to radiation GO:0009314 51 0.032
blood vessel development GO:0001568 246 0.032
Zebrafish
establishment of protein localization to organelle GO:0072594 4 0.032
growth GO:0040007 174 0.032
Zebrafish
water homeostasis GO:0030104 4 0.031
meiotic cell cycle process GO:1903046 3 0.031
proteasomal protein catabolic process GO:0010498 2 0.031
maintenance of location GO:0051235 4 0.031
neuron projection development GO:0031175 180 0.031
tube morphogenesis GO:0035239 349 0.030
Zebrafish Mouse
anatomical structure homeostasis GO:0060249 36 0.030
regulation of cell maturation GO:1903429 1 0.030
cardiocyte differentiation GO:0035051 44 0.030
negative regulation of gene expression GO:0010629 65 0.030
Mouse
taxis GO:0042330 109 0.030
positive regulation of catabolic process GO:0009896 4 0.029
muscle organ development GO:0007517 101 0.029
Mouse
cell cycle GO:0007049 93 0.029
protein localization to nucleus GO:0034504 3 0.029
negative regulation of oocyte development GO:0060283 2 0.028
negative regulation of cellular process GO:0048523 283 0.028
Mouse
cell aging GO:0007569 2 0.027
myotube differentiation GO:0014902 45 0.027
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
Human Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.027
Mouse
rna metabolic process GO:0016070 219 0.027
Human Zebrafish Mouse
proteolysis GO:0006508 38 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.026
regulation of response to stress GO:0080134 36 0.026
axonogenesis GO:0007409 152 0.026
cell death GO:0008219 121 0.026
Mouse
regulation of protein transport GO:0051223 3 0.026
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.026
Zebrafish
synaptic growth at neuromuscular junction GO:0051124 2 0.025
negative regulation of biosynthetic process GO:0009890 55 0.025
Mouse
homeostatic process GO:0042592 142 0.025
regulation of cell growth GO:0001558 29 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.024
nuclear transport GO:0051169 4 0.024
regulation of dna replication GO:0006275 3 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
regulation of signal transduction GO:0009966 225 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
Mouse
heart development GO:0007507 313 0.023
Zebrafish
microtubule organizing center organization GO:0031023 1 0.023
b cell activation GO:0042113 2 0.023
cognition GO:0050890 1 0.022
leukocyte proliferation GO:0070661 1 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regulation of developmental process GO:0050793 247 0.022
Zebrafish Mouse
positive regulation of signaling GO:0023056 56 0.022
cellular component morphogenesis GO:0032989 336 0.022
epithelial cell differentiation GO:0030855 116 0.021
Zebrafish Mouse
positive regulation of cellular process GO:0048522 201 0.021
Human Zebrafish Mouse
cardiac cell development GO:0055006 21 0.021
vasculature development GO:0001944 278 0.021
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.021
Mouse
axon development GO:0061564 166 0.021
neuronal action potential GO:0019228 18 0.021
determination of ventral identity GO:0048264 21 0.020
cellular component biogenesis GO:0044085 178 0.020
regulation of gene expression epigenetic GO:0040029 11 0.020
hormone secretion GO:0046879 2 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
Mouse
reproductive process GO:0022414 40 0.020
Mouse Fly
determination of heart left right asymmetry GO:0061371 117 0.020
Zebrafish
somitogenesis GO:0001756 87 0.020
cellular amine metabolic process GO:0044106 2 0.020
regeneration GO:0031099 91 0.020
Zebrafish
localization of cell GO:0051674 244 0.020
Zebrafish Mouse
regulation of intracellular protein transport GO:0033157 3 0.020
skeletal muscle tissue development GO:0007519 67 0.019
Mouse
head development GO:0060322 303 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
pancreas development GO:0031016 84 0.019
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
Human Zebrafish Mouse
positive regulation of blood circulation GO:1903524 2 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
digestive system development GO:0055123 289 0.018
Zebrafish
phagocytosis GO:0006909 3 0.018
regulation of cell communication GO:0010646 232 0.018
cellular response to radiation GO:0071478 4 0.018
cytokinesis GO:0000910 3 0.018
neurological system process GO:0050877 62 0.018
glucose import GO:0046323 2 0.018
regulation of cell development GO:0060284 100 0.018
Mouse
regulation of biosynthetic process GO:0009889 250 0.018
Human Zebrafish Mouse
macromolecular complex assembly GO:0065003 35 0.018
mitotic cell cycle process GO:1903047 48 0.018
organic acid metabolic process GO:0006082 31 0.018
single organism nuclear import GO:1902593 3 0.018
digestive tract development GO:0048565 265 0.018
Zebrafish
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
myofibril assembly GO:0030239 48 0.018
mechanosensory behavior GO:0007638 2 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
Mouse
ventricular system development GO:0021591 12 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
angiogenesis GO:0001525 158 0.017
positive regulation of neuron apoptotic process GO:0043525 1 0.017
locomotor rhythm GO:0045475 3 0.017
regulation of synapse assembly GO:0051963 3 0.017
cell morphogenesis GO:0000902 289 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.017
Human Mouse
stem cell development GO:0048864 82 0.017
Mouse
carboxylic acid metabolic process GO:0019752 22 0.017
single organism metabolic process GO:0044710 217 0.017
branching morphogenesis of a nerve GO:0048755 4 0.017
regulation of transporter activity GO:0032409 2 0.017
nuclear division GO:0000280 23 0.017
amine metabolic process GO:0009308 2 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
regulation of type b pancreatic cell development GO:2000074 1 0.017
hypothalamus cell differentiation GO:0021979 4 0.017
response to nutrient GO:0007584 3 0.017
regulation of histone methylation GO:0031060 3 0.017
regulation of protein catabolic process GO:0042176 1 0.017
protein complex subunit organization GO:0071822 46 0.017
action potential GO:0001508 19 0.017
developmental process involved in reproduction GO:0003006 27 0.016
Mouse Fly
single organism transport GO:0044765 206 0.016
cytoskeleton organization GO:0007010 96 0.016
positive regulation of striated muscle tissue development GO:0045844 1 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
Human Zebrafish Mouse
behavior GO:0007610 74 0.016
regulation of organelle assembly GO:1902115 4 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
protein modification process GO:0036211 100 0.015
organelle organization GO:0006996 227 0.015
regulation of cell differentiation GO:0045595 142 0.015
Zebrafish Mouse
glucose homeostasis GO:0042593 1 0.015
protein heterooligomerization GO:0051291 1 0.015
regulation of apoptotic process GO:0042981 98 0.015
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.015
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
Human Zebrafish Mouse
cell maturation GO:0048469 23 0.015
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.015
positive regulation of cell division GO:0051781 2 0.015
circadian regulation of gene expression GO:0032922 8 0.014
myotube cell development GO:0014904 35 0.014
Mouse
mononuclear cell proliferation GO:0032943 1 0.014
regulation of molecular function GO:0065009 70 0.014
Zebrafish
cellular response to starvation GO:0009267 1 0.014
nucleic acid templated transcription GO:0097659 181 0.014
Human Zebrafish Mouse
developmental maturation GO:0021700 34 0.014
Mouse
small molecule metabolic process GO:0044281 77 0.014
multicellular organismal signaling GO:0035637 22 0.014
regulation of cell size GO:0008361 29 0.014
cell projection morphogenesis GO:0048858 244 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
response to carbohydrate GO:0009743 3 0.014
photoreceptor cell outer segment organization GO:0035845 9 0.014
protein homooligomerization GO:0051260 3 0.014
reproduction GO:0000003 40 0.014
Mouse
neuron death GO:0070997 21 0.014
cellular response to light stimulus GO:0071482 4 0.014
nuclear import GO:0051170 3 0.014
ion transmembrane transport GO:0034220 91 0.013
negative regulation of signaling GO:0023057 96 0.013
carbohydrate homeostasis GO:0033500 1 0.013
establishment of localization GO:0051234 244 0.013
response to uv GO:0009411 3 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
photoreceptor cell differentiation GO:0046530 55 0.013
Mouse
regulation of growth GO:0040008 42 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
neural crest cell differentiation GO:0014033 72 0.013
Mouse
positive regulation of response to stimulus GO:0048584 80 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
cellular protein metabolic process GO:0044267 129 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
establishment of localization in cell GO:0051649 77 0.013
embryonic hemopoiesis GO:0035162 53 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
Human Zebrafish Mouse
macromolecule modification GO:0043412 111 0.012
oxoacid metabolic process GO:0043436 31 0.012
protein targeting to nucleus GO:0044744 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
transmembrane transport GO:0055085 120 0.012
centrosome organization GO:0051297 1 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
actin filament based process GO:0030029 64 0.012
cellular response to topologically incorrect protein GO:0035967 2 0.012
ear development GO:0043583 127 0.012
Zebrafish
protein complex assembly GO:0006461 30 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
Mouse
heart looping GO:0001947 94 0.012
gene silencing GO:0016458 4 0.012
signal transduction GO:0007165 455 0.012
Mouse
cardiac muscle tissue development GO:0048738 48 0.012
hemopoiesis GO:0030097 183 0.012
carbohydrate derivative metabolic process GO:1901135 61 0.012
germ cell migration GO:0008354 8 0.012
skeletal muscle fiber development GO:0048741 35 0.012
Mouse
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
regulation of protein metabolic process GO:0051246 56 0.012
activation of mapk activity GO:0000187 3 0.012
cellular response to stress GO:0033554 62 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.011
regulation of protein targeting GO:1903533 2 0.011
positive regulation of gene expression GO:0010628 71 0.011
Human Zebrafish Mouse
circadian behavior GO:0048512 5 0.011
type b pancreatic cell development GO:0003323 4 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
Mouse
circadian rhythm GO:0007623 19 0.011
developmental cell growth GO:0048588 52 0.011
stem cell division GO:0017145 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
retinal ganglion cell axon guidance GO:0031290 35 0.011
cardiac muscle cell development GO:0055013 20 0.011
regulation of membrane potential GO:0042391 23 0.011
embryonic organ development GO:0048568 381 0.011
Zebrafish
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.011
modification by symbiont of host morphology or physiology GO:0044003 4 0.011
regulation of axon extension GO:0030516 24 0.011
negative regulation of protein transport GO:0051224 3 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
somite development GO:0061053 96 0.011
protein import into nucleus GO:0006606 3 0.011
regulation of blood circulation GO:1903522 32 0.011
regulation of tube size GO:0035150 2 0.011
regulation of skeletal muscle fiber development GO:0048742 2 0.011
Mouse
peptide transport GO:0015833 1 0.010
regulation of neuron differentiation GO:0045664 56 0.010
Mouse
regulation of response to oxidative stress GO:1902882 2 0.010
regulation of gastrulation GO:0010470 24 0.010
Zebrafish
negative regulation of secretion GO:0051048 2 0.010
regulation of reproductive process GO:2000241 4 0.010
dna metabolic process GO:0006259 27 0.010
somatic cell dna recombination GO:0016444 1 0.010
cell substrate adhesion GO:0031589 4 0.010
cell migration GO:0016477 237 0.010
Zebrafish Mouse
hormone transport GO:0009914 2 0.010
sensory perception GO:0007600 39 0.010
nerve development GO:0021675 45 0.010
fin morphogenesis GO:0033334 53 0.010
Zebrafish
regulation of programmed cell death GO:0043067 101 0.010
Mouse
protein complex biogenesis GO:0070271 30 0.010

sox8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
reproductive system disease DOID:15 0 0.032
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.013
nervous system disease DOID:863 0 0.011