Danio rerio

95 known processes

sox3

SRY-box containing gene 3

(Aliases: wu:fd02a08,wu:fc93f07,sb:cb493,fc93f07,MGC110279,id:ibd2036,zgc:110279)

sox3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.982
sensory organ development GO:0007423 393 0.980
brain development GO:0007420 293 0.961
Mouse
peripheral nervous system development GO:0007422 55 0.960
neural tube development GO:0021915 62 0.958
eye development GO:0001654 277 0.951
Zebrafish
neuron fate commitment GO:0048663 26 0.937
astrocyte differentiation GO:0048708 1 0.931
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.904
regulation of inner ear receptor cell differentiation GO:2000980 1 0.903
generation of neurons GO:0048699 385 0.873
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.843
Zebrafish
embryonic organ development GO:0048568 381 0.832
camera type eye development GO:0043010 222 0.831
Zebrafish
inner ear development GO:0048839 126 0.809
neuromast development GO:0048884 46 0.806
epithelial cell differentiation GO:0030855 116 0.797
Zebrafish Mouse
regulation of rna metabolic process GO:0051252 224 0.797
digestive tract development GO:0048565 265 0.792
Zebrafish
cell fate specification GO:0001708 68 0.791
Zebrafish
dna templated transcription initiation GO:0006352 1 0.789
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.756
Zebrafish
positive regulation of notch signaling pathway GO:0045747 3 0.756
single organism reproductive process GO:0044702 40 0.744
Mouse Worm
endodermal cell fate determination GO:0007493 2 0.737
Zebrafish
cell proliferation in forebrain GO:0021846 3 0.732
digestive tract morphogenesis GO:0048546 231 0.725
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.724
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.692
dorsal ventral pattern formation GO:0009953 125 0.676
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.671
neuron projection morphogenesis GO:0048812 161 0.661
Fly
cell cycle GO:0007049 93 0.661
dopaminergic neuron differentiation GO:0071542 14 0.658
heterocycle biosynthetic process GO:0018130 215 0.652
eye morphogenesis GO:0048592 144 0.648
Zebrafish
regionalization GO:0003002 274 0.648
Zebrafish
neuron development GO:0048666 262 0.641
Zebrafish Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.636
cellular biosynthetic process GO:0044249 286 0.627
gliogenesis GO:0042063 45 0.626
Zebrafish
hindbrain development GO:0030902 91 0.622
neuronal stem cell maintenance GO:0097150 2 0.617
inner ear receptor cell fate commitment GO:0060120 4 0.617
regulation of mechanoreceptor differentiation GO:0045631 1 0.609
neuron differentiation GO:0030182 353 0.603
cardioblast migration GO:0003260 7 0.601
Zebrafish
reproductive process GO:0022414 40 0.596
Human Mouse Worm
macromolecule localization GO:0033036 54 0.595
epithelial cell development GO:0002064 42 0.594
Zebrafish Mouse
apoptotic process GO:0006915 116 0.591
negative regulation of cellular process GO:0048523 283 0.590
Mouse
tube morphogenesis GO:0035239 349 0.589
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.579
regulation of oligodendrocyte differentiation GO:0048713 1 0.574
cellular aromatic compound metabolic process GO:0006725 295 0.565
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.549
hypochord development GO:0055016 3 0.543
regulation of biological quality GO:0065008 263 0.532
cell fate commitment GO:0045165 99 0.529
Zebrafish
determination of left right symmetry GO:0007368 179 0.528
Zebrafish
ear morphogenesis GO:0042471 64 0.528
multi organism process GO:0051704 134 0.515
Mouse Worm
regulation of metabolic process GO:0019222 359 0.503
cellular component morphogenesis GO:0032989 336 0.501
Fly
heterocycle metabolic process GO:0046483 290 0.499
mesoderm development GO:0007498 88 0.491
Zebrafish
positive regulation of gene expression GO:0010628 71 0.485
Zebrafish Fly
retina development in camera type eye GO:0060041 146 0.480
Zebrafish
developmental process involved in reproduction GO:0003006 27 0.479
Human Mouse Worm
axon guidance GO:0007411 86 0.478
Fly
determination of pancreatic left right asymmetry GO:0035469 11 0.470
Zebrafish
mechanoreceptor differentiation GO:0042490 37 0.466
Zebrafish
axon development GO:0061564 166 0.465
Fly
cellular component movement GO:0006928 335 0.462
Zebrafish Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.440
Zebrafish
startle response GO:0001964 4 0.438
dorsal ventral axis specification GO:0009950 14 0.435
Zebrafish
patterning of lymph vessels GO:0060854 1 0.429
aorta development GO:0035904 4 0.428
negative regulation of biological process GO:0048519 304 0.422
Mouse
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.419
embryo development ending in birth or egg hatching GO:0009792 271 0.418
Worm
regulation of cell fate commitment GO:0010453 22 0.416
Zebrafish
regulation of cell differentiation GO:0045595 142 0.416
Zebrafish
cell migration to the midline involved in heart development GO:0003318 12 0.415
Zebrafish
stem cell maintenance GO:0019827 4 0.414
regulation of endodermal cell fate specification GO:0042663 15 0.407
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.400
formation of primary germ layer GO:0001704 62 0.398
Zebrafish
epithelial tube formation GO:0072175 19 0.394
transcription from rna polymerase ii promoter GO:0006366 80 0.388
Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.388
Zebrafish
gland development GO:0048732 143 0.387
Zebrafish Mouse
diencephalon development GO:0021536 58 0.383
Mouse
neuron projection guidance GO:0097485 86 0.381
Fly
somatic stem cell maintenance GO:0035019 1 0.380
regulation of cell communication GO:0010646 232 0.374
Fly
forebrain anterior posterior pattern specification GO:0021797 3 0.372
regulation of nervous system development GO:0051960 90 0.371
hair cell differentiation GO:0035315 32 0.368
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.362
axonogenesis GO:0007409 152 0.357
Fly
aromatic compound biosynthetic process GO:0019438 217 0.354
positive regulation of biosynthetic process GO:0009891 68 0.340
Zebrafish Fly
multi organism reproductive process GO:0044703 36 0.340
Mouse Worm
neuroblast fate commitment GO:0014017 1 0.332
cellular nitrogen compound metabolic process GO:0034641 290 0.331
negative regulation of gliogenesis GO:0014014 1 0.324
compound eye development GO:0048749 2 0.324
regulation of nitrogen compound metabolic process GO:0051171 251 0.319
cell proliferation in hindbrain GO:0021534 4 0.318
epithelial tube morphogenesis GO:0060562 148 0.317
cell motility GO:0048870 244 0.315
Zebrafish
neuroblast proliferation GO:0007405 2 0.315
regulation of biosynthetic process GO:0009889 250 0.314
auditory receptor cell fate commitment GO:0009912 4 0.310
regulation of multicellular organismal process GO:0051239 277 0.306
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.306
tube formation GO:0035148 25 0.302
neural crest formation GO:0014029 14 0.297
lateral inhibition GO:0046331 1 0.296
ear development GO:0043583 127 0.291
negative regulation of gene expression GO:0010629 65 0.290
Mouse
rna biosynthetic process GO:0032774 181 0.290
peripheral nervous system neuron differentiation GO:0048934 28 0.290
phosphate containing compound metabolic process GO:0006796 108 0.288
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.288
nucleic acid templated transcription GO:0097659 181 0.287
regulation of neural precursor cell proliferation GO:2000177 3 0.285
regulation of gene expression GO:0010468 265 0.280
cell morphogenesis GO:0000902 289 0.280
Fly
morphogenesis of an epithelium GO:0002009 333 0.278
glial cell development GO:0021782 20 0.273
cell projection morphogenesis GO:0048858 244 0.265
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.264
cartilage development GO:0051216 96 0.264
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.263
digestive system development GO:0055123 289 0.263
Zebrafish
pituitary gland development GO:0021983 16 0.263
Mouse
single organism organelle organization GO:1902589 199 0.263
negative regulation of biosynthetic process GO:0009890 55 0.257
Mouse
pancreas development GO:0031016 84 0.253
Zebrafish
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.252
cell part morphogenesis GO:0032990 246 0.250
Fly
nucleic acid metabolic process GO:0090304 244 0.250
epidermis development GO:0008544 48 0.248
connective tissue development GO:0061448 99 0.244
Zebrafish
central nervous system neuron differentiation GO:0021953 74 0.241
neural crest cell fate specification GO:0014036 5 0.237
negative regulation of multicellular organismal process GO:0051241 69 0.231
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.225
locomotion GO:0040011 313 0.224
Zebrafish Worm Fly
ectodermal placode morphogenesis GO:0071697 32 0.223
neuron fate specification GO:0048665 20 0.221
gastrulation GO:0007369 208 0.220
Zebrafish
fourth ventricle development GO:0021592 8 0.218
developmental pigmentation GO:0048066 48 0.216
Zebrafish
larval development GO:0002164 2 0.215
Worm
head development GO:0060322 303 0.214
Mouse
inner ear receptor cell development GO:0060119 20 0.213
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.213
Fly
epiboly GO:0090504 41 0.212
Zebrafish
cell death GO:0008219 121 0.211
retina morphogenesis in camera type eye GO:0060042 79 0.210
mesodermal cell fate commitment GO:0001710 14 0.210
heart formation GO:0060914 13 0.208
Zebrafish
neuroepithelial cell differentiation GO:0060563 26 0.206
Zebrafish
mesodermal cell fate specification GO:0007501 12 0.203
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.202
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.200
Zebrafish Fly
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.200
regulation of cellular metabolic process GO:0031323 320 0.199
stem cell fate determination GO:0048867 1 0.197
endodermal cell fate commitment GO:0001711 18 0.195
Zebrafish
cell migration involved in heart formation GO:0060974 10 0.194
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.194
chordate embryonic development GO:0043009 271 0.191
ventricular system development GO:0021591 12 0.184
maintenance of location GO:0051235 4 0.182
positive regulation of cellular metabolic process GO:0031325 94 0.182
Zebrafish Fly
primitive erythrocyte differentiation GO:0060319 5 0.182
segment specification GO:0007379 12 0.180
midbrain hindbrain boundary development GO:0030917 23 0.179
stem cell proliferation GO:0072089 4 0.179
mitotic cell cycle GO:0000278 64 0.178
rostrocaudal neural tube patterning GO:0021903 29 0.177
regulation of glial cell differentiation GO:0045685 4 0.176
organic substance biosynthetic process GO:1901576 289 0.175
positive regulation of transcription dna templated GO:0045893 57 0.172
Zebrafish Fly
forebrain development GO:0030900 96 0.172
Mouse
biosynthetic process GO:0009058 294 0.171
positive regulation of secretion by cell GO:1903532 1 0.171
regulation of cell proliferation GO:0042127 37 0.168
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.168
Mouse
mammillary body development GO:0021767 4 0.167
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.166
neuroblast fate determination GO:0007400 1 0.165
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.164
brain morphogenesis GO:0048854 18 0.164
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.163
negative regulation of stem cell differentiation GO:2000737 2 0.161
behavior GO:0007610 74 0.161
Worm
negative regulation of cell differentiation GO:0045596 46 0.161
sensory system development GO:0048880 76 0.159
ectodermal placode formation GO:0060788 26 0.158
negative regulation of developmental process GO:0051093 65 0.158
neuron fate determination GO:0048664 2 0.156
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.156
Mouse Fly
phosphorus metabolic process GO:0006793 109 0.156
regulation of macromolecule metabolic process GO:0060255 317 0.156
organelle organization GO:0006996 227 0.156
regulation of canonical wnt signaling pathway GO:0060828 34 0.155
lipid storage GO:0019915 1 0.154
reproduction GO:0000003 40 0.152
Mouse Worm
radial glial cell differentiation GO:0060019 2 0.149
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.148
endothelial cell fate commitment GO:0060839 3 0.146
otic vesicle development GO:0071599 42 0.146
regulation of primary metabolic process GO:0080090 311 0.145
midbrain development GO:0030901 28 0.145
negative regulation of protein phosphorylation GO:0001933 4 0.145
posterior lateral line neuromast development GO:0048919 20 0.143
equilibrioception GO:0050957 2 0.143
cellular macromolecule biosynthetic process GO:0034645 224 0.142
neural crest cell fate commitment GO:0014034 5 0.142
tube closure GO:0060606 1 0.141
anterior posterior pattern specification GO:0009952 152 0.140
cell cycle g1 s phase transition GO:0044843 1 0.139
regulation of notch signaling pathway GO:0008593 16 0.139
abducens nucleus development GO:0021742 2 0.137
cell differentiation in spinal cord GO:0021515 40 0.137
gene expression GO:0010467 252 0.137
cell migration involved in heart development GO:0060973 22 0.135
Zebrafish
aorta morphogenesis GO:0035909 3 0.134
positive regulation of metabolic process GO:0009893 108 0.132
Zebrafish Fly
liver development GO:0001889 96 0.131
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.131
programmed cell death GO:0012501 119 0.130
canonical wnt signaling pathway GO:0060070 48 0.128
negative regulation of epithelial cell migration GO:0010633 1 0.127
negative regulation of nervous system development GO:0051961 22 0.126
negative regulation of cell migration GO:0030336 17 0.121
oligodendrocyte development GO:0014003 7 0.118
endoderm formation GO:0001706 29 0.118
Zebrafish
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.118
response to wounding GO:0009611 116 0.118
Zebrafish
negative regulation of endothelial cell migration GO:0010596 1 0.118
regulation of catenin import into nucleus GO:0035412 2 0.117
notch signaling pathway GO:0007219 35 0.116
endothelial cell development GO:0001885 12 0.116
Zebrafish
regulation of gliogenesis GO:0014013 6 0.114
posterior lateral line system development GO:0048915 46 0.113
embryonic camera type eye development GO:0031076 29 0.113
positive regulation of neural precursor cell proliferation GO:2000179 1 0.112
forebrain generation of neurons GO:0021872 14 0.110
regulation of signal transduction GO:0009966 225 0.110
Fly
skeletal system development GO:0001501 181 0.110
Zebrafish
nuclear transport GO:0051169 4 0.110
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.109
epidermal cell fate specification GO:0009957 4 0.109
cellular protein metabolic process GO:0044267 129 0.109
regulation of rna biosynthetic process GO:2001141 213 0.108
organelle fission GO:0048285 23 0.107
heart development GO:0007507 313 0.107
Zebrafish
forebrain neuron fate commitment GO:0021877 1 0.106
olfactory placode formation GO:0030910 1 0.106
cell proliferation in midbrain GO:0033278 4 0.106
negative regulation of neurogenesis GO:0050768 20 0.105
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.104
embryonic organ morphogenesis GO:0048562 274 0.104
morphogenesis of embryonic epithelium GO:0016331 30 0.103
regulation of apoptotic process GO:0042981 98 0.103
neural precursor cell proliferation GO:0061351 20 0.103
glial cell differentiation GO:0010001 42 0.102
Zebrafish
transcription dna templated GO:0006351 181 0.102
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.102
Fly
embryonic heart tube development GO:0035050 133 0.101
Zebrafish
limbic system development GO:0021761 16 0.101
Mouse
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.100
localization of cell GO:0051674 244 0.100
Zebrafish
embryonic epithelial tube formation GO:0001838 17 0.099
myotome development GO:0061055 1 0.098
negative regulation of cellular biosynthetic process GO:0031327 55 0.098
Mouse
reproductive structure development GO:0048608 5 0.095
Mouse Worm
epidermal cell differentiation GO:0009913 36 0.094
embryonic skeletal system development GO:0048706 97 0.094
cell cell signaling involved in cell fate commitment GO:0045168 12 0.094
wnt signaling pathway GO:0016055 80 0.094
Fly
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.093
cellular response to external stimulus GO:0071496 2 0.093
mitotic nuclear division GO:0007067 18 0.091
macromolecule biosynthetic process GO:0009059 227 0.091
central nervous system myelination GO:0022010 2 0.091
palate development GO:0060021 8 0.090
Zebrafish
vasculogenesis GO:0001570 41 0.090
Zebrafish
taxis GO:0042330 109 0.090
Fly
meiotic nuclear division GO:0007126 4 0.090
regulation of nucleic acid templated transcription GO:1903506 213 0.090
fin development GO:0033333 77 0.089
Zebrafish
posterior lateral line development GO:0048916 38 0.089
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.088
Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.088
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.088
mitotic cell cycle process GO:1903047 48 0.086
inner ear morphogenesis GO:0042472 63 0.086
response to stress GO:0006950 263 0.085
Zebrafish
death GO:0016265 121 0.085
signal transduction GO:0007165 455 0.084
Fly
detection of mechanical stimulus GO:0050982 11 0.084
neural tube formation GO:0001841 16 0.081
regulation of cell development GO:0060284 100 0.081
cell projection organization GO:0030030 284 0.081
Fly
anterior commissure morphogenesis GO:0021960 3 0.081
stem cell development GO:0048864 82 0.081
regeneration GO:0031099 91 0.081
Zebrafish
endothelium development GO:0003158 25 0.080
Zebrafish
proximal distal pattern formation GO:0009954 1 0.080
regulation of cell death GO:0010941 103 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.078
Zebrafish Fly
negative regulation of cellular metabolic process GO:0031324 77 0.078
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.078
Fly
cellular macromolecule metabolic process GO:0044260 391 0.077
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.077
diencephalon morphogenesis GO:0048852 5 0.077
cellular response to retinoic acid GO:0071300 1 0.076
regulation of gastrulation GO:0010470 24 0.075
Zebrafish
negative regulation of cell development GO:0010721 26 0.074
cell proliferation GO:0008283 80 0.074
spinal cord development GO:0021510 46 0.074
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.073
Zebrafish
regulation of response to stimulus GO:0048583 269 0.073
Fly
positive regulation of transport GO:0051050 2 0.073
embryonic cranial skeleton morphogenesis GO:0048701 90 0.072
negative regulation of notch signaling pathway GO:0045746 6 0.072
anterior head development GO:0097065 2 0.072
regulation of cell cycle GO:0051726 52 0.071
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.071
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.070
cartilage morphogenesis GO:0060536 13 0.069
Zebrafish
organic substance transport GO:0071702 58 0.069
oligodendrocyte differentiation GO:0048709 23 0.069
Zebrafish
regulation of intracellular protein transport GO:0033157 3 0.068
regulation of cytokine production GO:0001817 3 0.068
g1 s transition of mitotic cell cycle GO:0000082 1 0.068
inner ear receptor cell differentiation GO:0060113 29 0.068
Zebrafish
positive regulation of stem cell proliferation GO:2000648 1 0.066
regulation of stem cell differentiation GO:2000736 4 0.066
determination of heart left right asymmetry GO:0061371 117 0.066
Zebrafish
epithelial cell fate commitment GO:0072148 11 0.066
germ line stem cell maintenance GO:0030718 2 0.066
positive regulation of cell cycle GO:0045787 3 0.065
fin regeneration GO:0031101 51 0.065
Zebrafish
otic vesicle formation GO:0030916 27 0.065
cell cycle process GO:0022402 53 0.064
negative regulation of protein kinase activity GO:0006469 4 0.064
single organism localization GO:1902578 225 0.063
regulation of neurogenesis GO:0050767 87 0.063
neuromuscular process GO:0050905 7 0.063
photoreceptor cell fate commitment GO:0046552 1 0.062
metencephalon development GO:0022037 27 0.062
negative regulation of neuron differentiation GO:0045665 10 0.061
ectodermal placode development GO:0071696 37 0.060
forebrain neuron differentiation GO:0021879 14 0.060
regulation of cell migration GO:0030334 40 0.060
positive regulation of rna metabolic process GO:0051254 59 0.060
Zebrafish Fly
lymph vessel development GO:0001945 27 0.060
multicellular organism reproduction GO:0032504 35 0.059
Mouse Worm
negative regulation of locomotion GO:0040013 18 0.059
mesenchymal cell differentiation GO:0048762 87 0.058
blood vessel development GO:0001568 246 0.058
Zebrafish
immune system process GO:0002376 241 0.057
endodermal cell fate specification GO:0001714 17 0.057
Zebrafish
mesenchymal cell development GO:0014031 78 0.056
hepaticobiliary system development GO:0061008 98 0.056
Zebrafish
stem cell fate commitment GO:0048865 1 0.056
cellular protein modification process GO:0006464 100 0.056
regulation of cellular biosynthetic process GO:0031326 245 0.055
detection of temperature stimulus GO:0016048 0 0.055
brain segmentation GO:0035284 6 0.055
positive regulation of biological process GO:0048518 253 0.054
negative regulation of nuclear division GO:0051784 3 0.054
regulation of ectoderm development GO:2000383 2 0.054
neural tube patterning GO:0021532 33 0.052
neuroblast differentiation GO:0014016 1 0.051
negative regulation of kinase activity GO:0033673 4 0.051
wound healing GO:0042060 90 0.051
Zebrafish
epithelial to mesenchymal transition GO:0001837 21 0.051
primary neural tube formation GO:0014020 1 0.051
pigment biosynthetic process GO:0046148 9 0.050
neuron projection development GO:0031175 180 0.050
Fly
negative regulation of mitosis GO:0045839 3 0.050
regulation of transcription dna templated GO:0006355 213 0.050
nucleocytoplasmic transport GO:0006913 4 0.050
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.049
pigment cell differentiation GO:0050931 38 0.049
Zebrafish
response to drug GO:0042493 3 0.049
keratinocyte differentiation GO:0030216 0 0.049
ventricular cardiac muscle tissue development GO:0003229 3 0.049
positive regulation of translation GO:0045727 1 0.049
cell cycle arrest GO:0007050 1 0.048
negative regulation of metabolic process GO:0009892 86 0.048
Mouse
rhombomere morphogenesis GO:0021593 17 0.048
olfactory placode morphogenesis GO:0071699 7 0.048
circadian rhythm GO:0007623 19 0.047
endodermal cell differentiation GO:0035987 19 0.047
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.047
gtp metabolic process GO:0046039 4 0.047
kidney development GO:0001822 92 0.046
negative regulation of signal transduction GO:0009968 94 0.046
nephron epithelium development GO:0072009 16 0.046
development of primary sexual characteristics GO:0045137 5 0.046
Mouse Worm
retinal cell programmed cell death GO:0046666 2 0.046
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.046
tissue regeneration GO:0042246 74 0.046
Zebrafish
vasculature development GO:0001944 278 0.046
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.045
regulation of somitogenesis GO:0014807 1 0.045
ventral spinal cord interneuron fate commitment GO:0060579 3 0.045
heart looping GO:0001947 94 0.045
otic placode formation GO:0043049 23 0.044
phagocytosis GO:0006909 3 0.044
forebrain morphogenesis GO:0048853 6 0.044
specification of symmetry GO:0009799 204 0.043
Zebrafish
nephron development GO:0072006 31 0.043
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 7 0.043
rna metabolic process GO:0016070 219 0.042
negative regulation of cytokine production GO:0001818 1 0.042
regulation of locomotion GO:0040012 55 0.042
cell migration GO:0016477 237 0.042
Zebrafish
gtp catabolic process GO:0006184 2 0.042
proteasomal protein catabolic process GO:0010498 2 0.041
positive regulation of epithelial cell differentiation GO:0030858 2 0.041
regulation of mitotic cell cycle GO:0007346 25 0.041
developmental programmed cell death GO:0010623 4 0.040
regulation of binding GO:0051098 3 0.040
response to chemical GO:0042221 320 0.040
Fly
optic nerve morphogenesis GO:0021631 6 0.040
urogenital system development GO:0001655 97 0.040
cellular component biogenesis GO:0044085 178 0.040
regulation of molecular function GO:0065009 70 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.039
axis specification GO:0009798 43 0.039
Zebrafish
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.039
epithelial cell morphogenesis GO:0003382 2 0.038
regulation of cell activation GO:0050865 1 0.037
regulation of developmental process GO:0050793 247 0.037
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.037
cellular response to stress GO:0033554 62 0.036
small molecule metabolic process GO:0044281 77 0.036
positive regulation of glial cell differentiation GO:0045687 1 0.036
regulation of myeloid cell differentiation GO:0045637 8 0.036
rhombomere development GO:0021546 19 0.036
gastrulation with mouth forming second GO:0001702 44 0.036
Zebrafish
photoreceptor cell differentiation GO:0046530 55 0.036
thalamus development GO:0021794 6 0.035
sensory perception GO:0007600 39 0.035
regulation of translational initiation GO:0006446 1 0.035
regulation of programmed cell death GO:0043067 101 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.035
Mouse
artery development GO:0060840 22 0.035
Zebrafish
negative regulation of myeloid cell differentiation GO:0045638 1 0.035
central nervous system segmentation GO:0035283 6 0.034
posttranscriptional regulation of gene expression GO:0010608 14 0.034
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.034
Mouse
eye photoreceptor cell development GO:0042462 30 0.034
nuclear division GO:0000280 23 0.034
cellular response to extracellular stimulus GO:0031668 2 0.034
neural crest cell differentiation GO:0014033 72 0.034
cellular response to organic substance GO:0071310 105 0.034
regulation of protein metabolic process GO:0051246 56 0.033
peripheral nervous system neuron axonogenesis GO:0048936 13 0.033
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
Zebrafish Fly
neuron neuron synaptic transmission GO:0007270 1 0.032
endothelial cell differentiation GO:0045446 20 0.032
Zebrafish
sex differentiation GO:0007548 5 0.032
Mouse Worm
positive regulation of gliogenesis GO:0014015 2 0.032
positive regulation of protein kinase b signaling GO:0051897 1 0.032
positive regulation of cellular process GO:0048522 201 0.031
Zebrafish Fly
regulation of cytoplasmic transport GO:1903649 4 0.031
forebrain dorsal ventral pattern formation GO:0021798 1 0.031
hindbrain morphogenesis GO:0021575 22 0.031
negative regulation of macromolecule metabolic process GO:0010605 76 0.031
Mouse
negative regulation of epithelial cell proliferation GO:0050680 1 0.031
transport GO:0006810 220 0.031
negative regulation of cellular component movement GO:0051271 18 0.031
isoprenoid metabolic process GO:0006720 15 0.031
hemopoiesis GO:0030097 183 0.031
embryonic eye morphogenesis GO:0048048 30 0.030
renal tubule morphogenesis GO:0061333 1 0.030

sox3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 0 0.066
developmental disorder of mental health DOID:0060037 0 0.066
sensory system disease DOID:0050155 0 0.060
microphthalmia DOID:10629 0 0.060
disease of anatomical entity DOID:7 0 0.060
eye and adnexa disease DOID:1492 0 0.060
nervous system disease DOID:863 0 0.060
eye disease DOID:5614 0 0.060