Danio rerio

0 known processes

sox6

SRY-box containing gene 6

sox6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.094
Mouse
larval development GO:0002164 2 0.088
Worm
gene expression GO:0010467 252 0.065
Mouse
cellular component morphogenesis GO:0032989 336 0.060
Mouse
signal transduction GO:0007165 455 0.059
regulation of organelle assembly GO:1902115 4 0.056
generation of neurons GO:0048699 385 0.055
regulation of gene expression GO:0010468 265 0.053
Mouse
striated muscle cell differentiation GO:0051146 129 0.051
Mouse
muscle cell differentiation GO:0042692 139 0.050
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.047
Mouse
blood vessel development GO:0001568 246 0.047
negative regulation of cellular process GO:0048523 283 0.045
Mouse
multicellular organism growth GO:0035264 4 0.044
neuron differentiation GO:0030182 353 0.044
positive regulation of transport GO:0051050 2 0.044
maintenance of location GO:0051235 4 0.044
cellular macromolecule metabolic process GO:0044260 391 0.043
Mouse
nitrogen compound metabolic process GO:0006807 319 0.040
Mouse
negative regulation of biological process GO:0048519 304 0.038
Mouse
heterocycle biosynthetic process GO:0018130 215 0.037
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.037
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.036
Mouse
nucleoside monophosphate catabolic process GO:0009125 4 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.036
Mouse
muscle structure development GO:0061061 196 0.036
Mouse
muscle tissue development GO:0060537 110 0.035
Mouse
transcription dna templated GO:0006351 181 0.034
Mouse
response to chemical GO:0042221 320 0.033
Human
organic substance biosynthetic process GO:1901576 289 0.033
Mouse
regulation of developmental process GO:0050793 247 0.033
Human Mouse
cell motility GO:0048870 244 0.033
cell projection organization GO:0030030 284 0.033
muscle organ development GO:0007517 101 0.032
negative regulation of synapse assembly GO:0051964 2 0.031
locomotion GO:0040011 313 0.031
Worm
regulation of cellular metabolic process GO:0031323 320 0.031
Mouse
positive regulation of cellular process GO:0048522 201 0.031
Human Mouse
cell death GO:0008219 121 0.031
macromolecule biosynthetic process GO:0009059 227 0.030
Mouse
regulation of synapse assembly GO:0051963 3 0.030
phagocytosis GO:0006909 3 0.030
skeletal muscle organ development GO:0060538 78 0.029
cellular component movement GO:0006928 335 0.029
actin polymerization or depolymerization GO:0008154 2 0.029
positive regulation of cell cycle GO:0045787 3 0.028
embryo development ending in birth or egg hatching GO:0009792 271 0.028
Mouse
neuron development GO:0048666 262 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
Mouse
regulation of multicellular organism growth GO:0040014 4 0.028
cell migration GO:0016477 237 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.027
heterocycle metabolic process GO:0046483 290 0.027
Mouse
response to alkaloid GO:0043279 2 0.026
cellular amine metabolic process GO:0044106 2 0.026
rna biosynthetic process GO:0032774 181 0.026
Mouse
aging GO:0007568 2 0.026
system process GO:0003008 185 0.026
cellular protein catabolic process GO:0044257 4 0.025
positive regulation of biological process GO:0048518 253 0.025
Human Mouse
protein localization to nucleus GO:0034504 3 0.025
regulation of primary metabolic process GO:0080090 311 0.025
Mouse
single organism localization GO:1902578 225 0.025
striated muscle cell development GO:0055002 108 0.024
muscle cell development GO:0055001 115 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
regulation of cell communication GO:0010646 232 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
cellular modified amino acid metabolic process GO:0006575 3 0.024
immune system development GO:0002520 191 0.024
Mouse
nucleocytoplasmic transport GO:0006913 4 0.024
vasculature development GO:0001944 278 0.024
amine metabolic process GO:0009308 2 0.024
regulation of response to stimulus GO:0048583 269 0.023
cell substrate adhesion GO:0031589 4 0.023
musculoskeletal movement GO:0050881 8 0.023
localization of cell GO:0051674 244 0.023
regulation of reproductive process GO:2000241 4 0.023
response to stress GO:0006950 263 0.023
angiogenesis GO:0001525 158 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
mitochondrion organization GO:0007005 4 0.022
outflow tract morphogenesis GO:0003151 1 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
regulation of signal transduction GO:0009966 225 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.021
Mouse
blood vessel morphogenesis GO:0048514 216 0.021
regulation of muscle contraction GO:0006937 3 0.021
lipid storage GO:0019915 1 0.021
cellular ketone metabolic process GO:0042180 11 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
regulation of cell differentiation GO:0045595 142 0.021
Human Mouse
response to drug GO:0042493 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
nuclear transport GO:0051169 4 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
Human Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
atp catabolic process GO:0006200 4 0.020
regulation of biological quality GO:0065008 263 0.020
Mouse
cellular carbohydrate metabolic process GO:0044262 4 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
anterior posterior pattern specification GO:0009952 152 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
meiotic nuclear division GO:0007126 4 0.019
wnt signaling pathway GO:0016055 80 0.019
death GO:0016265 121 0.019
cognition GO:0050890 1 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
striated muscle tissue development GO:0014706 110 0.019
Mouse
regulation of synapse organization GO:0050807 3 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
Human Mouse
tube morphogenesis GO:0035239 349 0.019
somatic muscle development GO:0007525 4 0.019
regulation of transcription dna templated GO:0006355 213 0.019
Mouse
muscle cell migration GO:0014812 4 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
immune system process GO:0002376 241 0.019
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
cell morphogenesis GO:0000902 289 0.018
Mouse
regulation of protein transport GO:0051223 3 0.018
regulation of cell development GO:0060284 100 0.018
neuron projection morphogenesis GO:0048812 161 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
cell projection morphogenesis GO:0048858 244 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
post embryonic organ development GO:0048569 4 0.018
Worm
regulation of biosynthetic process GO:0009889 250 0.018
Mouse
protein polymerization GO:0051258 4 0.018
cell part morphogenesis GO:0032990 246 0.017
stem cell proliferation GO:0072089 4 0.017
convergent extension GO:0060026 118 0.017
neuron projection development GO:0031175 180 0.017
growth GO:0040007 174 0.017
cellular protein metabolic process GO:0044267 129 0.017
muscle fiber development GO:0048747 52 0.017
response to wounding GO:0009611 116 0.017
sensory organ development GO:0007423 393 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
phosphorus metabolic process GO:0006793 109 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
multicellular organismal metabolic process GO:0044236 2 0.017
transport GO:0006810 220 0.017
response to external stimulus GO:0009605 264 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
Mouse
regulation of protein complex assembly GO:0043254 3 0.016
cellular component disassembly GO:0022411 1 0.016
developmental growth GO:0048589 166 0.016
release of sequestered calcium ion into cytosol GO:0051209 3 0.016
skeletal muscle tissue development GO:0007519 67 0.016
regulation of cell activation GO:0050865 1 0.016
protein metabolic process GO:0019538 183 0.016
Worm
cellular response to chemical stimulus GO:0070887 157 0.016
Human
cell matrix adhesion GO:0007160 4 0.016
regulation of rna metabolic process GO:0051252 224 0.016
Mouse
cellular component assembly GO:0022607 170 0.016
regionalization GO:0003002 274 0.016
programmed cell death GO:0012501 119 0.015
convergent extension involved in gastrulation GO:0060027 71 0.015
locomotor rhythm GO:0045475 3 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
Mouse
syncytium formation GO:0006949 12 0.015
tissue regeneration GO:0042246 74 0.015
negative regulation of signaling GO:0023057 96 0.015
adult behavior GO:0030534 2 0.015
intracellular signal transduction GO:0035556 85 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
homeostatic process GO:0042592 142 0.015
Mouse
myotube differentiation GO:0014902 45 0.015
regulation of circadian rhythm GO:0042752 4 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
stem cell differentiation GO:0048863 117 0.015
Human
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
single organism metabolic process GO:0044710 217 0.015
urogenital system development GO:0001655 97 0.015
centrosome organization GO:0051297 1 0.015
head development GO:0060322 303 0.015
nucleic acid templated transcription GO:0097659 181 0.015
Mouse
axon development GO:0061564 166 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
glucose import GO:0046323 2 0.014
regulation of binding GO:0051098 3 0.014
renal system development GO:0072001 94 0.014
myotube cell development GO:0014904 35 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.014
organelle assembly GO:0070925 110 0.014
cell cycle arrest GO:0007050 1 0.014
regulation of protein catabolic process GO:0042176 1 0.014
nucleic acid metabolic process GO:0090304 244 0.014
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
compound eye development GO:0048749 2 0.014
microtubule organizing center organization GO:0031023 1 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
regulation of cytokine production GO:0001817 3 0.014
protein import GO:0017038 3 0.014
regeneration GO:0031099 91 0.014
establishment of localization GO:0051234 244 0.014
regulation of cell projection assembly GO:0060491 4 0.014
rna metabolic process GO:0016070 219 0.014
Mouse
embryonic organ morphogenesis GO:0048562 274 0.014
stem cell maintenance GO:0019827 4 0.014
germ line stem cell maintenance GO:0030718 2 0.014
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.014
cellular biosynthetic process GO:0044249 286 0.014
Mouse
positive regulation of cell adhesion GO:0045785 1 0.014
nuclear import GO:0051170 3 0.014
actin filament polymerization GO:0030041 2 0.014
actin filament based process GO:0030029 64 0.014
single organism nuclear import GO:1902593 3 0.014
digestive system development GO:0055123 289 0.014
biosynthetic process GO:0009058 294 0.014
Mouse
hemopoiesis GO:0030097 183 0.013
Mouse
adherens junction organization GO:0034332 4 0.013
chordate embryonic development GO:0043009 271 0.013
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.013
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.013
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
positive regulation of catabolic process GO:0009896 4 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
negative regulation of metabolic process GO:0009892 86 0.013
Mouse
regulation of signaling GO:0023051 235 0.013
negative regulation of gene expression GO:0010629 65 0.013
Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.013
multi organism process GO:0051704 134 0.013
Worm
skeletal muscle fiber development GO:0048741 35 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
Mouse
pericardium development GO:0060039 1 0.013
leukocyte proliferation GO:0070661 1 0.013
regulation of cell death GO:0010941 103 0.013
protein targeting to nucleus GO:0044744 3 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
Mouse
cytoskeleton organization GO:0007010 96 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
chemotaxis GO:0006935 104 0.012
regulation of apoptotic process GO:0042981 98 0.012
tissue remodeling GO:0048771 4 0.012
positive regulation of cytokine production GO:0001819 2 0.012
single organism organelle organization GO:1902589 199 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
Mouse
internal peptidyl lysine acetylation GO:0018393 2 0.012
regulation of protein polymerization GO:0032271 2 0.012
multi organism cellular process GO:0044764 2 0.012
energy reserve metabolic process GO:0006112 2 0.012
phosphorylation GO:0016310 69 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.012
Mouse
membrane invagination GO:0010324 1 0.012
rna localization GO:0006403 4 0.012
negative regulation of signal transduction GO:0009968 94 0.012
protein import into nucleus GO:0006606 3 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
Mouse
negative regulation of catabolic process GO:0009895 3 0.012
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
regulation of inflammatory response GO:0050727 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of dendrite development GO:0050773 3 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
protein complex disassembly GO:0043241 1 0.011
embryonic organ development GO:0048568 381 0.011
somite development GO:0061053 96 0.011
regulation of cellular component organization GO:0051128 86 0.011
taxis GO:0042330 109 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
Mouse
cardiac muscle tissue development GO:0048738 48 0.011
Mouse
negative regulation of mapk cascade GO:0043409 4 0.011
lymphocyte proliferation GO:0046651 1 0.011
mononuclear cell proliferation GO:0032943 1 0.011
mesoderm development GO:0007498 88 0.011
viral process GO:0016032 1 0.011
female gonad development GO:0008585 4 0.011
regulation of oocyte development GO:0060281 3 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
positive regulation of reproductive process GO:2000243 2 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
Mouse
regulation of programmed cell death GO:0043067 101 0.011
hard palate development GO:0060022 4 0.011
lipid homeostasis GO:0055088 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
nitric oxide metabolic process GO:0046209 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
Mouse
response to organic substance GO:0010033 153 0.011
Human
regulation of nucleoside metabolic process GO:0009118 2 0.011
nucleic acid transport GO:0050657 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
negative regulation of cell communication GO:0010648 96 0.011
developmental programmed cell death GO:0010623 4 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
cell substrate junction assembly GO:0007044 2 0.011
lateral inhibition GO:0046331 1 0.011
heart development GO:0007507 313 0.011
Mouse
small molecule metabolic process GO:0044281 77 0.011
guanosine containing compound catabolic process GO:1901069 2 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
macromolecular complex disassembly GO:0032984 1 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
neuronal action potential GO:0019228 18 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
meiotic cell cycle process GO:1903046 3 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
muscle contraction GO:0006936 18 0.010
negative regulation of cytokine production GO:0001818 1 0.010
cellular component biogenesis GO:0044085 178 0.010
regulation of protein targeting GO:1903533 2 0.010
actin cytoskeleton organization GO:0030036 63 0.010
organelle organization GO:0006996 227 0.010
zymogen activation GO:0031638 3 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
oxoacid metabolic process GO:0043436 31 0.010
sarcomere organization GO:0045214 26 0.010
single organism transport GO:0044765 206 0.010
eye development GO:0001654 277 0.010
female sex differentiation GO:0046660 4 0.010
synaptic target recognition GO:0008039 1 0.010
canonical wnt signaling pathway GO:0060070 48 0.010
protein complex biogenesis GO:0070271 30 0.010
response to corticosteroid GO:0031960 1 0.010
macromolecule modification GO:0043412 111 0.010
protein homooligomerization GO:0051260 3 0.010

sox6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
musculoskeletal system disease DOID:17 0 0.022
nervous system disease DOID:863 0 0.019
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
connective tissue disease DOID:65 0 0.012
sensory system disease DOID:0050155 0 0.011
disease of cellular proliferation DOID:14566 0 0.010