Danio rerio

30 known processes

irx3b

iroquois homeobox protein 3b

(Aliases: ziro3b,zgc:76885,wu:fb36a07)

irx3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.756
rhombomere 5 morphogenesis GO:0021664 1 0.720
brain development GO:0007420 293 0.661
neuron neuron synaptic transmission GO:0007270 1 0.594
head development GO:0060322 303 0.594
sensory organ development GO:0007423 393 0.548
rhombomere boundary formation GO:0021654 10 0.498
regulation of cellular metabolic process GO:0031323 320 0.448
lymph vessel morphogenesis GO:0036303 25 0.440
synaptic transmission GO:0007268 35 0.412
rhombomere development GO:0021546 19 0.405
cellular macromolecule biosynthetic process GO:0034645 224 0.392
anatomical structure arrangement GO:0048532 2 0.381
cellular component movement GO:0006928 335 0.367
transport GO:0006810 220 0.364
dendrite guidance GO:0070983 0 0.352
regulation of nitrogen compound metabolic process GO:0051171 251 0.351
facial nerve morphogenesis GO:0021610 1 0.335
stem cell fate commitment GO:0048865 1 0.325
neuron projection development GO:0031175 180 0.294
epithelial cell differentiation GO:0030855 116 0.294
nucleobase containing compound biosynthetic process GO:0034654 205 0.277
rhombomere morphogenesis GO:0021593 17 0.276
positive regulation of biological process GO:0048518 253 0.275
neuron differentiation GO:0030182 353 0.270
facial nerve development GO:0021561 3 0.267
hair cell differentiation GO:0035315 32 0.260
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.258
peripheral nervous system neuron differentiation GO:0048934 28 0.249
transcription dna templated GO:0006351 181 0.244
regulation of multicellular organismal process GO:0051239 277 0.242
heterocycle biosynthetic process GO:0018130 215 0.234
larval development GO:0002164 2 0.232
axonogenesis GO:0007409 152 0.215
organic substance biosynthetic process GO:1901576 289 0.203
regulation of transcription dna templated GO:0006355 213 0.203
establishment of localization GO:0051234 244 0.201
apoptotic process involved in development GO:1902742 2 0.200
rhombomere 5 development GO:0021571 4 0.195
cellular component morphogenesis GO:0032989 336 0.193
wnt signaling pathway GO:0016055 80 0.192
positive regulation of cellular process GO:0048522 201 0.192
regulation of wnt signaling pathway GO:0030111 53 0.191
detection of temperature stimulus GO:0016048 0 0.188
cellular biosynthetic process GO:0044249 286 0.177
endothelial cell fate commitment GO:0060839 3 0.174
epidermis development GO:0008544 48 0.174
signal transduction GO:0007165 455 0.172
regulation of cell development GO:0060284 100 0.169
negative regulation of axon regeneration GO:0048681 4 0.164
regulation of primary metabolic process GO:0080090 311 0.164
embryonic organ development GO:0048568 381 0.160
extracellular structure organization GO:0043062 27 0.159
negative regulation of cellular process GO:0048523 283 0.155
synaptic transmission cholinergic GO:0007271 4 0.154
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.150
regulation of biosynthetic process GO:0009889 250 0.150
hormone transport GO:0009914 2 0.147
positive regulation of gene expression GO:0010628 71 0.146
regulation of endodermal cell differentiation GO:1903224 15 0.146
midbrain hindbrain boundary development GO:0030917 23 0.132
transcription from rna polymerase iii promoter GO:0006383 1 0.130
macromolecule biosynthetic process GO:0009059 227 0.126
negative regulation of neuron projection regeneration GO:0070571 4 0.123
developmental programmed cell death GO:0010623 4 0.123
regulation of endodermal cell fate specification GO:0042663 15 0.122
aging GO:0007568 2 0.120
negative regulation of biological process GO:0048519 304 0.118
cell morphogenesis involved in differentiation GO:0000904 195 0.118
regulation of cell fate commitment GO:0010453 22 0.113
digestive system development GO:0055123 289 0.112
cell fate specification GO:0001708 68 0.111
ectoderm development GO:0007398 9 0.109
lymphatic endothelial cell fate commitment GO:0060838 1 0.109
cellular nitrogen compound metabolic process GO:0034641 290 0.109
regulation of gastrulation GO:0010470 24 0.106
rna metabolic process GO:0016070 219 0.100
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.100
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.099
maintenance of location GO:0051235 4 0.097
cell part morphogenesis GO:0032990 246 0.097
negative regulation of collateral sprouting GO:0048671 2 0.097
positive regulation of cellular component biogenesis GO:0044089 3 0.094
aromatic compound biosynthetic process GO:0019438 217 0.093
regulation of cell differentiation GO:0045595 142 0.092
response to chemical GO:0042221 320 0.089
neuromast mantle cell differentiation GO:0048888 1 0.088
regulation of embryonic development GO:0045995 47 0.088
hindbrain development GO:0030902 91 0.085
regulation of nervous system development GO:0051960 90 0.083
regulation of rna biosynthetic process GO:2001141 213 0.080
negative regulation of cell development GO:0010721 26 0.078
hemopoiesis GO:0030097 183 0.076
embryonic organ morphogenesis GO:0048562 274 0.076
cell projection organization GO:0030030 284 0.076
regulation of rna metabolic process GO:0051252 224 0.075
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.075
sensory system development GO:0048880 76 0.075
regulation of nucleic acid templated transcription GO:1903506 213 0.074
fin regeneration GO:0031101 51 0.071
rhombomere formation GO:0021594 12 0.071
peptide transport GO:0015833 1 0.070
adult behavior GO:0030534 2 0.068
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.067
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.067
anterior posterior pattern specification GO:0009952 152 0.067
nucleic acid templated transcription GO:0097659 181 0.067
generation of neurons GO:0048699 385 0.066
gene expression GO:0010467 252 0.065
ear development GO:0043583 127 0.062
cellular macromolecule metabolic process GO:0044260 391 0.061
organic substance transport GO:0071702 58 0.061
cellular nitrogen compound biosynthetic process GO:0044271 218 0.061
regulation of cell communication GO:0010646 232 0.060
glomerular visceral epithelial cell fate commitment GO:0072149 4 0.060
regulation of multicellular organismal development GO:2000026 223 0.060
cell surface receptor signaling pathway GO:0007166 325 0.059
hematopoietic or lymphoid organ development GO:0048534 191 0.059
negative regulation of chemotaxis GO:0050922 4 0.059
regulation of cell projection organization GO:0031344 44 0.059
epidermal cell differentiation GO:0009913 36 0.059
negative regulation of nucleic acid templated transcription GO:1903507 45 0.058
lymphatic endothelial cell differentiation GO:0060836 1 0.057
mechanosensory lateral line system development GO:0048881 49 0.056
cellular component assembly GO:0022607 170 0.056
regulation of neuron differentiation GO:0045664 56 0.056
adherens junction organization GO:0034332 4 0.056
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.055
cell cell signaling GO:0007267 52 0.054
regulation of anatomical structure morphogenesis GO:0022603 130 0.053
cellular localization GO:0051641 97 0.053
immune system process GO:0002376 241 0.051
lateral line system development GO:0048925 76 0.051
locomotion GO:0040011 313 0.051
lymphangiogenesis GO:0001946 25 0.050
convergent extension GO:0060026 118 0.050
negative regulation of metabolic process GO:0009892 86 0.049
dna templated transcription initiation GO:0006352 1 0.049
positive regulation of metabolic process GO:0009893 108 0.049
forebrain development GO:0030900 96 0.049
regulation of neurogenesis GO:0050767 87 0.048
transcription from rna polymerase ii promoter GO:0006366 80 0.048
single organism localization GO:1902578 225 0.047
regulation of dendrite morphogenesis GO:0048814 3 0.047
regulation of stem cell differentiation GO:2000736 4 0.046
sensory neuron axon guidance GO:0097374 3 0.046
single organism metabolic process GO:0044710 217 0.046
nucleic acid metabolic process GO:0090304 244 0.045
embryonic cranial skeleton morphogenesis GO:0048701 90 0.045
lymph vessel development GO:0001945 27 0.045
regulation of organ growth GO:0046620 3 0.045
segment polarity determination GO:0007367 1 0.045
inorganic cation transmembrane transport GO:0098662 50 0.044
negative regulation of protein kinase activity GO:0006469 4 0.043
skin development GO:0043588 54 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.042
regulation of metabolic process GO:0019222 359 0.042
regulation of gene expression GO:0010468 265 0.042
morphogenesis of embryonic epithelium GO:0016331 30 0.041
glomerular epithelial cell fate commitment GO:0072314 4 0.041
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.041
regulation of protein transport GO:0051223 3 0.041
regulation of macromolecule metabolic process GO:0060255 317 0.041
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.041
neuron development GO:0048666 262 0.040
cellular response to retinoic acid GO:0071300 1 0.040
chordate embryonic development GO:0043009 271 0.040
regulation of erk1 and erk2 cascade GO:0070372 4 0.039
heterocycle metabolic process GO:0046483 290 0.039
endodermal cell differentiation GO:0035987 19 0.039
cation transport GO:0006812 81 0.039
rhombomere 6 development GO:0021572 4 0.039
regulation of developmental process GO:0050793 247 0.038
negative regulation of axon guidance GO:1902668 1 0.038
single organism transport GO:0044765 206 0.038
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.038
receptor internalization GO:0031623 2 0.037
digestive tract morphogenesis GO:0048546 231 0.037
blood vessel development GO:0001568 246 0.036
embryonic skeletal system morphogenesis GO:0048704 93 0.035
retinoic acid receptor signaling pathway GO:0048384 16 0.035
actomyosin structure organization GO:0031032 53 0.034
phagocytosis GO:0006909 3 0.034
negative regulation of gene expression GO:0010629 65 0.034
hormone secretion GO:0046879 2 0.033
positive regulation of rna biosynthetic process GO:1902680 57 0.033
female sex differentiation GO:0046660 4 0.033
tissue migration GO:0090130 37 0.033
vasculature development GO:0001944 278 0.033
nephron development GO:0072006 31 0.033
regulation of cell fate specification GO:0042659 20 0.032
olfactory bulb axon guidance GO:0071678 3 0.032
segmentation GO:0035282 97 0.032
regulation of dna methylation GO:0044030 5 0.032
lipid storage GO:0019915 1 0.032
central nervous system neuron differentiation GO:0021953 74 0.032
positive regulation of transcription dna templated GO:0045893 57 0.031
negative regulation of transcription dna templated GO:0045892 45 0.031
cellular protein modification process GO:0006464 100 0.031
cellular component assembly involved in morphogenesis GO:0010927 107 0.030
ion transmembrane transport GO:0034220 91 0.030
cellular amine metabolic process GO:0044106 2 0.030
protein secretion GO:0009306 1 0.030
positive regulation of cellular biosynthetic process GO:0031328 68 0.029
methylation GO:0032259 22 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
response to carbohydrate GO:0009743 3 0.028
cell projection morphogenesis GO:0048858 244 0.028
gastrulation GO:0007369 208 0.028
negative regulation of mitosis GO:0045839 3 0.028
positive regulation of axon guidance GO:1902669 1 0.028
branching morphogenesis of an epithelial tube GO:0048754 15 0.028
negative regulation of granulocyte chemotaxis GO:0071623 3 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
negative regulation of epithelial cell migration GO:0010633 1 0.027
ion transport GO:0006811 114 0.027
carbon dioxide transport GO:0015670 3 0.026
rostrocaudal neural tube patterning GO:0021903 29 0.026
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.026
regulation of dendrite development GO:0050773 3 0.026
pronephric nephron development GO:0039019 14 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
hindbrain morphogenesis GO:0021575 22 0.025
wound healing GO:0042060 90 0.025
regulation of neurological system process GO:0031644 2 0.025
response to light stimulus GO:0009416 46 0.025
protein modification process GO:0036211 100 0.025
embryonic digestive tract morphogenesis GO:0048557 3 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
negative regulation of map kinase activity GO:0043407 2 0.025
central nervous system neuron development GO:0021954 29 0.025
glial cell development GO:0021782 20 0.025
inner ear morphogenesis GO:0042472 63 0.025
kidney development GO:0001822 92 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.024
collateral sprouting of intact axon in response to injury GO:0048673 2 0.024
muscle cell development GO:0055001 115 0.024
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
positive regulation of macromolecule metabolic process GO:0010604 93 0.024
cell morphogenesis GO:0000902 289 0.023
negative chemotaxis GO:0050919 1 0.023
response to external stimulus GO:0009605 264 0.023
posterior lateral line nerve glial cell differentiation GO:0048931 5 0.023
embryonic viscerocranium morphogenesis GO:0048703 52 0.023
immune system development GO:0002520 191 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
angiogenesis GO:0001525 158 0.023
skeletal system morphogenesis GO:0048705 102 0.023
negative regulation of signal transduction GO:0009968 94 0.023
negative regulation of stem cell differentiation GO:2000737 2 0.023
intrahepatic bile duct development GO:0035622 11 0.023
tube morphogenesis GO:0035239 349 0.023
positive regulation of gastrulation GO:2000543 2 0.023
motor neuron axon guidance GO:0008045 23 0.022
production of molecular mediator of immune response GO:0002440 2 0.022
angioblast cell migration GO:0035476 9 0.022
stem cell differentiation GO:0048863 117 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
oocyte maturation GO:0001556 4 0.022
negative regulation of mapk cascade GO:0043409 4 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
epithelial cell fate commitment GO:0072148 11 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
neuron projection guidance GO:0097485 86 0.022
positive regulation of biosynthetic process GO:0009891 68 0.022
negative regulation of developmental process GO:0051093 65 0.021
positive regulation of muscle tissue development GO:1901863 1 0.021
biosynthetic process GO:0009058 294 0.021
peripheral nervous system neuron axonogenesis GO:0048936 13 0.020
nerve development GO:0021675 45 0.020
formation of anatomical boundary GO:0048859 14 0.020
dorsal spinal cord development GO:0021516 1 0.020
positive regulation of nucleic acid templated transcription GO:1903508 57 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.020
secondary metabolic process GO:0019748 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
cell substrate adhesion GO:0031589 4 0.020
branching morphogenesis of a nerve GO:0048755 4 0.020
cartilage development GO:0051216 96 0.019
axon ensheathment in central nervous system GO:0032291 2 0.019
appendage development GO:0048736 80 0.019
embryonic limb morphogenesis GO:0030326 2 0.019
regulation of signaling GO:0023051 235 0.019
response to vitamin b3 GO:0033552 2 0.019
cellular lipid metabolic process GO:0044255 36 0.019
mesoderm formation GO:0001707 43 0.019
regulation of photoreceptor cell differentiation GO:0046532 2 0.019
hypothalamus development GO:0021854 14 0.019
death GO:0016265 121 0.019
astrocyte differentiation GO:0048708 1 0.019
sodium ion transport GO:0006814 24 0.019
negative regulation of signaling GO:0023057 96 0.019
multicellular organismal signaling GO:0035637 22 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
cell cell recognition GO:0009988 1 0.018
retinoic acid metabolic process GO:0042573 9 0.018
embryonic digestive tract development GO:0048566 4 0.018
central nervous system segmentation GO:0035283 6 0.018
cell proliferation in forebrain GO:0021846 3 0.018
endodermal cell fate commitment GO:0001711 18 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
rhombomere 4 morphogenesis GO:0021661 5 0.018
regulation of fatty acid metabolic process GO:0019217 1 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
blood vessel endothelial cell migration GO:0043534 18 0.018
negative regulation of rna metabolic process GO:0051253 48 0.018
regulation of cell morphogenesis GO:0022604 42 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
neuroblast differentiation GO:0014016 1 0.018
negative regulation of cell migration GO:0030336 17 0.018
monovalent inorganic cation transport GO:0015672 42 0.018
growth GO:0040007 174 0.018
erk1 and erk2 cascade GO:0070371 4 0.017
growth plate cartilage development GO:0003417 2 0.017
female gonad development GO:0008585 4 0.017
regulation of neuronal synaptic plasticity GO:0048168 1 0.017
otolith morphogenesis GO:0032474 8 0.017
regulation of ph GO:0006885 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
response to hexose GO:0009746 3 0.017
cell fate commitment GO:0045165 99 0.017
response to monosaccharide GO:0034284 3 0.017
commissural neuron axon guidance GO:0071679 3 0.017
embryonic appendage morphogenesis GO:0035113 30 0.016
regulation of skeletal muscle fiber development GO:0048742 2 0.016
negative regulation of locomotion GO:0040013 18 0.016
regulation of neuron projection development GO:0010975 40 0.016
cellular component biogenesis GO:0044085 178 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
oligopeptide transport GO:0006857 1 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
rna biosynthetic process GO:0032774 181 0.016
melanin metabolic process GO:0006582 2 0.016
organelle assembly GO:0070925 110 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
cell motility GO:0048870 244 0.016
regulation of myotube differentiation GO:0010830 2 0.016
epithelial cell morphogenesis GO:0003382 2 0.016
branchiomotor neuron axon guidance GO:0021785 1 0.016
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.015
sodium ion transmembrane transport GO:0035725 21 0.015
regulation of neuron projection regeneration GO:0070570 7 0.015
response to glucose GO:0009749 3 0.015
protein targeting to membrane GO:0006612 1 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
regulation of biological quality GO:0065008 263 0.015
neuroblast fate commitment GO:0014017 1 0.015
embryonic skeletal system development GO:0048706 97 0.015
synaptic target recognition GO:0008039 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
negative regulation of reproductive process GO:2000242 3 0.015
response to organic substance GO:0010033 153 0.015
morphogenesis of a branching structure GO:0001763 21 0.015
regulation of filopodium assembly GO:0051489 2 0.015
positive regulation of axon extension involved in axon guidance GO:0048842 1 0.015
diencephalon development GO:0021536 58 0.015
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.015
common bile duct development GO:0061009 13 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
regulation of signal transduction GO:0009966 225 0.015
spinal cord development GO:0021510 46 0.015
tube closure GO:0060606 1 0.014
lateral line development GO:0048882 66 0.014
blood vessel morphogenesis GO:0048514 216 0.014
dendrite development GO:0016358 9 0.014
regulation of cell activation GO:0050865 1 0.014
midbrain development GO:0030901 28 0.014
monoamine transport GO:0015844 1 0.014
intracellular receptor signaling pathway GO:0030522 30 0.014
regulation of protein complex assembly GO:0043254 3 0.014
regulation of cell projection assembly GO:0060491 4 0.014
positive regulation of striated muscle cell differentiation GO:0051155 1 0.014
somatic muscle development GO:0007525 4 0.014
posterior lateral line system development GO:0048915 46 0.014
cellular response to oxygen levels GO:0071453 1 0.013
hypotonic salinity response GO:0042539 5 0.013
ear morphogenesis GO:0042471 64 0.013
positive regulation of rna metabolic process GO:0051254 59 0.013
epithelial cell proliferation GO:0050673 17 0.013
nitrogen compound transport GO:0071705 23 0.013
distal tubule development GO:0072017 1 0.013
negative regulation of cell motility GO:2000146 17 0.013
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.013
regulation of reproductive process GO:2000241 4 0.013
neural tube development GO:0021915 62 0.013
chloride transport GO:0006821 8 0.013
renal absorption GO:0070293 1 0.013
axon development GO:0061564 166 0.013
pronephric nephron tubule development GO:0039020 2 0.013
otic vesicle development GO:0071599 42 0.013
cell migration GO:0016477 237 0.013
myofibril assembly GO:0030239 48 0.013
response to oxygen containing compound GO:1901700 55 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of cellular component organization GO:0051128 86 0.013
sodium ion import GO:0097369 3 0.013
digestive tract development GO:0048565 265 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
metal ion transport GO:0030001 58 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
stem cell proliferation GO:0072089 4 0.012
brain segmentation GO:0035284 6 0.012
positive regulation of secretion GO:0051047 1 0.012
auditory receptor cell morphogenesis GO:0002093 4 0.012
macromolecule modification GO:0043412 111 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
gas transport GO:0015669 3 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
single organism reproductive process GO:0044702 40 0.012
protein metabolic process GO:0019538 183 0.012
endocytosis GO:0006897 16 0.012
bicarbonate transport GO:0015701 4 0.012
entrainment of circadian clock by photoperiod GO:0043153 1 0.012
mechanoreceptor differentiation GO:0042490 37 0.012
ossification GO:0001503 23 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
cellular lipid catabolic process GO:0044242 3 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.011
negative regulation of axon extension GO:0030517 7 0.011
endodermal cell fate determination GO:0007493 2 0.011
response to amphetamine GO:0001975 1 0.011
trabecula formation GO:0060343 2 0.011
chemosensory behavior GO:0007635 1 0.011
nephron morphogenesis GO:0072028 2 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
embryonic pattern specification GO:0009880 44 0.011
axis elongation GO:0003401 31 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
histone h3 k4 methylation GO:0051568 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
response to radiation GO:0009314 51 0.011
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.011
negative regulation of protein transport GO:0051224 3 0.011
response to vitamin GO:0033273 3 0.011
amine metabolic process GO:0009308 2 0.011
axon guidance GO:0007411 86 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
negative regulation of cellular component movement GO:0051271 18 0.011
positive regulation of transport GO:0051050 2 0.011
cellular response to nutrient levels GO:0031669 2 0.011
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 1 0.011
localization of cell GO:0051674 244 0.011
macromolecule methylation GO:0043414 19 0.011
fin morphogenesis GO:0033334 53 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.010
regulation of tube size GO:0035150 2 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.010
liver morphogenesis GO:0072576 8 0.010
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.010
dendrite morphogenesis GO:0048813 5 0.010
urogenital system development GO:0001655 97 0.010
response to lipid GO:0033993 60 0.010
sympathetic ganglion development GO:0061549 2 0.010
negative regulation of nervous system development GO:0051961 22 0.010
type b pancreatic cell differentiation GO:0003309 8 0.010

irx3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
charcot marie tooth disease type 4 DOID:0050541 0 0.155
neuromuscular disease DOID:440 0 0.155
disease of anatomical entity DOID:7 0 0.155
charcot marie tooth disease DOID:10595 0 0.155
nervous system disease DOID:863 0 0.155
neuropathy DOID:870 0 0.155
urinary system cancer DOID:3996 0 0.093
cancer DOID:162 0 0.093
disease of cellular proliferation DOID:14566 0 0.093
organ system cancer DOID:0050686 0 0.093
diabetes mellitus DOID:9351 0 0.055
type 2 diabetes mellitus DOID:9352 0 0.055
disease of metabolism DOID:0014667 0 0.055
carbohydrate metabolism disease DOID:0050013 0 0.055
glucose metabolism disease DOID:4194 0 0.055
acquired metabolic disease DOID:0060158 0 0.055
maturity onset diabetes of the young DOID:0050524 0 0.043
musculoskeletal system cancer DOID:0060100 0 0.026