Danio rerio

22 known processes

irx3a

iroquois homeobox protein 3a

(Aliases: id:ibd3380,hm:zehn0543,wu:fk88a03,iro3,MGC109805,irx3,zgc:109805)

irx3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.999
Zebrafish
larval development GO:0002164 2 0.991
Worm
regulation of response to stimulus GO:0048583 269 0.961
cell surface receptor signaling pathway GO:0007166 325 0.952
central nervous system development GO:0007417 387 0.931
Zebrafish
neuron differentiation GO:0030182 353 0.923
Zebrafish Mouse
locomotion GO:0040011 313 0.906
camera type eye morphogenesis GO:0048593 108 0.903
Zebrafish
cell motility GO:0048870 244 0.855
regulation of cell communication GO:0010646 232 0.846
regionalization GO:0003002 274 0.839
Mouse
neural tube development GO:0021915 62 0.835
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.829
Zebrafish
epithelial cell differentiation GO:0030855 116 0.829
Zebrafish
neuron fate commitment GO:0048663 26 0.822
chordate embryonic development GO:0043009 271 0.814
positive regulation of cellular process GO:0048522 201 0.798
Mouse
signal transduction GO:0007165 455 0.748
cell fate commitment GO:0045165 99 0.728
cell migration GO:0016477 237 0.716
localization of cell GO:0051674 244 0.654
embryonic organ development GO:0048568 381 0.651
Zebrafish
rostrocaudal neural tube patterning GO:0021903 29 0.646
blood vessel morphogenesis GO:0048514 216 0.633
regulation of signaling GO:0023051 235 0.627
midbrain hindbrain boundary development GO:0030917 23 0.603
regulation of primary metabolic process GO:0080090 311 0.592
digestive tract morphogenesis GO:0048546 231 0.583
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.566
digestive tract development GO:0048565 265 0.529
tube morphogenesis GO:0035239 349 0.521
vasculature development GO:0001944 278 0.515
stem cell proliferation GO:0072089 4 0.510
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.498
appendage development GO:0048736 80 0.485
Zebrafish
positive regulation of biological process GO:0048518 253 0.480
Mouse
negative regulation of response to stimulus GO:0048585 104 0.476
embryo development ending in birth or egg hatching GO:0009792 271 0.473
Worm
fourth ventricle development GO:0021592 8 0.468
aorta development GO:0035904 4 0.459
generation of neurons GO:0048699 385 0.458
Zebrafish Mouse
regulation of rna biosynthetic process GO:2001141 213 0.453
blood vessel development GO:0001568 246 0.437
macromolecule biosynthetic process GO:0009059 227 0.433
cellular macromolecule metabolic process GO:0044260 391 0.432
inner ear morphogenesis GO:0042472 63 0.419
Zebrafish
mesenchyme development GO:0060485 127 0.417
regulation of cellular metabolic process GO:0031323 320 0.407
specification of symmetry GO:0009799 204 0.404
neuron projection development GO:0031175 180 0.395
camera type eye development GO:0043010 222 0.390
Zebrafish
digestive system development GO:0055123 289 0.388
regulation of metabolic process GO:0019222 359 0.365
epithelial tube morphogenesis GO:0060562 148 0.353
Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.345
ear development GO:0043583 127 0.342
Zebrafish
eye morphogenesis GO:0048592 144 0.339
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.334
angiogenesis GO:0001525 158 0.333
regulation of cell differentiation GO:0045595 142 0.327
Mouse
stem cell development GO:0048864 82 0.325
neuron development GO:0048666 262 0.321
Zebrafish
single organism reproductive process GO:0044702 40 0.319
regulation of anatomical structure morphogenesis GO:0022603 130 0.316
heterocycle metabolic process GO:0046483 290 0.315
eye development GO:0001654 277 0.314
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.314
neural precursor cell proliferation GO:0061351 20 0.310
neural crest cell differentiation GO:0014033 72 0.310
forebrain anterior posterior pattern specification GO:0021797 3 0.305
glandular epithelial cell differentiation GO:0002067 9 0.302
regulation of nitrogen compound metabolic process GO:0051171 251 0.295
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.295
gastrulation GO:0007369 208 0.295
neuroblast proliferation GO:0007405 2 0.287
thalamus development GO:0021794 6 0.283
nucleobase containing compound metabolic process GO:0006139 274 0.278
negative regulation of signal transduction GO:0009968 94 0.277
cell morphogenesis GO:0000902 289 0.275
organic cyclic compound metabolic process GO:1901360 301 0.271
brain development GO:0007420 293 0.270
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.260
dorsal ventral pattern formation GO:0009953 125 0.257
determination of bilateral symmetry GO:0009855 204 0.255
response to organic substance GO:0010033 153 0.248
central nervous system myelination GO:0022010 2 0.244
cellular biosynthetic process GO:0044249 286 0.241
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.241
regulation of transcription dna templated GO:0006355 213 0.240
protein targeting to nucleus GO:0044744 3 0.238
pancreatic a cell development GO:0003322 2 0.238
immune system development GO:0002520 191 0.237
regulation of developmental process GO:0050793 247 0.236
Mouse
transcription dna templated GO:0006351 181 0.233
response to chemical GO:0042221 320 0.229
mesoderm development GO:0007498 88 0.228
Mouse
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.227
response to external stimulus GO:0009605 264 0.224
determination of left right symmetry GO:0007368 179 0.224
regulation of cellular ketone metabolic process GO:0010565 7 0.223
astrocyte differentiation GO:0048708 1 0.222
embryonic skeletal system development GO:0048706 97 0.222
compound eye development GO:0048749 2 0.220
autonomic nervous system development GO:0048483 19 0.218
morphogenesis of an epithelium GO:0002009 333 0.217
Mouse
positive regulation of transport GO:0051050 2 0.217
negative regulation of cellular process GO:0048523 283 0.216
Mouse
cellular component movement GO:0006928 335 0.215
eye photoreceptor cell differentiation GO:0001754 45 0.214
Zebrafish
hair cell differentiation GO:0035315 32 0.211
Zebrafish
axon development GO:0061564 166 0.208
regulation of gene expression GO:0010468 265 0.205
cell part morphogenesis GO:0032990 246 0.202
regulation of cytokine production GO:0001817 3 0.202
regulation of macromolecule biosynthetic process GO:0010556 225 0.200
hematopoietic or lymphoid organ development GO:0048534 191 0.199
skeletal system development GO:0001501 181 0.196
regulation of biosynthetic process GO:0009889 250 0.195
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.191
neuroepithelial cell differentiation GO:0060563 26 0.190
inner ear development GO:0048839 126 0.186
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.184
embryonic limb morphogenesis GO:0030326 2 0.182
ventral spinal cord interneuron fate commitment GO:0060579 3 0.182
endothelial cell fate commitment GO:0060839 3 0.181
nitrogen compound metabolic process GO:0006807 319 0.181
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.178
spinal cord development GO:0021510 46 0.174
cellular component morphogenesis GO:0032989 336 0.173
regulation of cellular biosynthetic process GO:0031326 245 0.167
axonogenesis GO:0007409 152 0.165
neuron projection guidance GO:0097485 86 0.162
regulation of neurogenesis GO:0050767 87 0.161
Mouse
retina development in camera type eye GO:0060041 146 0.161
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.159
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.159
neural crest cell development GO:0014032 62 0.158
epithelial tube formation GO:0072175 19 0.152
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.150
positive regulation of cell differentiation GO:0045597 30 0.150
Mouse
positive regulation of signal transduction GO:0009967 56 0.145
wnt signaling pathway GO:0016055 80 0.144
pronephric glomerulus development GO:0039021 13 0.135
posterior lateral line system development GO:0048915 46 0.130
Zebrafish
cell proliferation GO:0008283 80 0.129
keratinocyte differentiation GO:0030216 0 0.127
negative regulation of protein phosphorylation GO:0001933 4 0.127
negative regulation of cell communication GO:0010648 96 0.126
segment polarity determination GO:0007367 1 0.125
positive regulation of protein kinase b signaling GO:0051897 1 0.125
atrioventricular valve formation GO:0003190 3 0.125
cell projection organization GO:0030030 284 0.124
transcription from rna polymerase iii promoter GO:0006383 1 0.123
cell differentiation in spinal cord GO:0021515 40 0.122
fin development GO:0033333 77 0.121
Zebrafish
type b pancreatic cell development GO:0003323 4 0.120
sensory organ morphogenesis GO:0090596 200 0.117
Zebrafish
sympathetic nervous system development GO:0048485 3 0.115
nuclear transport GO:0051169 4 0.114
epidermis development GO:0008544 48 0.114
Zebrafish
stem cell differentiation GO:0048863 117 0.114
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.113
regulation of signal transduction GO:0009966 225 0.113
stem cell maintenance GO:0019827 4 0.113
epithelial cell development GO:0002064 42 0.112
cell projection morphogenesis GO:0048858 244 0.109
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.108
pectoral fin morphogenesis GO:0035138 29 0.108
Zebrafish
cardioblast migration GO:0003260 7 0.107
organic substance biosynthetic process GO:1901576 289 0.107
neural tube formation GO:0001841 16 0.107
anterior head development GO:0097065 2 0.106
mesenchymal cell development GO:0014031 78 0.106
negative regulation of signaling GO:0023057 96 0.105
dorsal aorta development GO:0035907 4 0.103
lipid storage GO:0019915 1 0.101
positive regulation of cell proliferation GO:0008284 15 0.100
stem cell division GO:0017145 1 0.098
kidney development GO:0001822 92 0.097
Mouse
positive regulation of cell communication GO:0010647 56 0.096
cell proliferation in hindbrain GO:0021534 4 0.095
cellular response to chemical stimulus GO:0070887 157 0.095
protein import into nucleus GO:0006606 3 0.093
regeneration GO:0031099 91 0.092
protein acylation GO:0043543 3 0.091
transcription from rna polymerase ii promoter GO:0006366 80 0.089
growth GO:0040007 174 0.089
primary neural tube formation GO:0014020 1 0.088
positive regulation of neuron migration GO:2001224 2 0.088
heart development GO:0007507 313 0.088
programmed cell death GO:0012501 119 0.088
metencephalon development GO:0022037 27 0.087
ventricular system development GO:0021591 12 0.086
pancreas development GO:0031016 84 0.084
nucleocytoplasmic transport GO:0006913 4 0.084
cellular nitrogen compound metabolic process GO:0034641 290 0.084
macromolecular complex subunit organization GO:0043933 74 0.084
positive regulation of neuron differentiation GO:0045666 12 0.083
Mouse
epidermal cell fate specification GO:0009957 4 0.083
hindbrain morphogenesis GO:0021575 22 0.082
Zebrafish
regulation of cellular response to growth factor stimulus GO:0090287 35 0.080
motor neuron axon guidance GO:0008045 23 0.079
immune system process GO:0002376 241 0.079
taxis GO:0042330 109 0.079
aorta morphogenesis GO:0035909 3 0.079
leukocyte differentiation GO:0002521 25 0.079
rna biosynthetic process GO:0032774 181 0.078
regulation of cell activation GO:0050865 1 0.078
otic vesicle formation GO:0030916 27 0.078
positive regulation of response to stimulus GO:0048584 80 0.076
establishment of protein localization to organelle GO:0072594 4 0.073
neural tube patterning GO:0021532 33 0.072
neural retina development GO:0003407 49 0.072
Zebrafish
determination of pancreatic left right asymmetry GO:0035469 11 0.072
cell proliferation in forebrain GO:0021846 3 0.072
regulation of neuron projection development GO:0010975 40 0.071
protein acetylation GO:0006473 2 0.071
epidermal cell differentiation GO:0009913 36 0.071
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.070
head development GO:0060322 303 0.070
Zebrafish
cell fate specification GO:0001708 68 0.068
reproductive process GO:0022414 40 0.068
endocrine pancreas development GO:0031018 27 0.067
regulation of nucleic acid templated transcription GO:1903506 213 0.065
protein import GO:0017038 3 0.065
regulation of wnt signaling pathway GO:0030111 53 0.064
regulation of multicellular organismal process GO:0051239 277 0.064
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.064
regulation of gastrulation GO:0010470 24 0.064
pancreatic d cell differentiation GO:0003311 2 0.064
epithelial to mesenchymal transition GO:0001837 21 0.064
regulation of cell fate commitment GO:0010453 22 0.064
sensory perception GO:0007600 39 0.064
regulation of glial cell differentiation GO:0045685 4 0.063
positive regulation of neuron apoptotic process GO:0043525 1 0.062
cellular protein metabolic process GO:0044267 129 0.062
neural plate pattern specification GO:0060896 12 0.062
skeletal system morphogenesis GO:0048705 102 0.062
regulation of protein import into nucleus GO:0042306 2 0.061
regulation of apoptotic process GO:0042981 98 0.061
hindbrain development GO:0030902 91 0.061
Zebrafish
nuclear import GO:0051170 3 0.060
atrioventricular valve morphogenesis GO:0003181 6 0.059
regulation of establishment of protein localization GO:0070201 4 0.059
type b pancreatic cell differentiation GO:0003309 8 0.058
neural nucleus development GO:0048857 15 0.058
developmental growth GO:0048589 166 0.058
myeloid cell homeostasis GO:0002262 56 0.057
gene expression GO:0010467 252 0.057
rhombomere development GO:0021546 19 0.056
regulation of collateral sprouting GO:0048670 7 0.056
heart morphogenesis GO:0003007 156 0.056
neuromast mantle cell differentiation GO:0048888 1 0.056
Zebrafish
neural plate anterior posterior regionalization GO:0021999 8 0.055
cell migration involved in gastrulation GO:0042074 79 0.055
abducens nucleus development GO:0021742 2 0.055
homeostatic process GO:0042592 142 0.054
positive regulation of cell activation GO:0050867 1 0.054
cellular protein catabolic process GO:0044257 4 0.053
regulation of binding GO:0051098 3 0.053
appendage morphogenesis GO:0035107 56 0.052
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.051
mesodermal cell fate commitment GO:0001710 14 0.051
neuron neuron synaptic transmission GO:0007270 1 0.050
Worm
regulation of neural precursor cell proliferation GO:2000177 3 0.050
anterior posterior pattern specification GO:0009952 152 0.050
negative regulation of multicellular organismal process GO:0051241 69 0.050
Mouse
erythrocyte differentiation GO:0030218 54 0.050
gastrulation with mouth forming second GO:0001702 44 0.049
cell differentiation in hindbrain GO:0021533 5 0.049
regulation of oligodendrocyte differentiation GO:0048713 1 0.049
embryonic skeletal system morphogenesis GO:0048704 93 0.049
regulation of cellular component organization GO:0051128 86 0.049
connective tissue development GO:0061448 99 0.048
negative regulation of biosynthetic process GO:0009890 55 0.048
urogenital system development GO:0001655 97 0.048
Mouse
negative regulation of locomotion GO:0040013 18 0.048
enteroendocrine cell differentiation GO:0035883 9 0.048
regulation of inner ear receptor cell differentiation GO:2000980 1 0.048
regulation of angiogenesis GO:0045765 26 0.047
skin development GO:0043588 54 0.047
Zebrafish
regulation of protein localization to nucleus GO:1900180 2 0.047
cellular response to retinoic acid GO:0071300 1 0.046
facial nucleus development GO:0021754 7 0.046
peripheral nervous system neuron axonogenesis GO:0048936 13 0.046
determination of liver left right asymmetry GO:0071910 11 0.045
nephron tubule epithelial cell differentiation GO:0072160 1 0.044
lymphatic endothelial cell fate commitment GO:0060838 1 0.044
anterior commissure morphogenesis GO:0021960 3 0.044
axon guidance GO:0007411 86 0.044
germ line stem cell maintenance GO:0030718 2 0.044
rna metabolic process GO:0016070 219 0.043
regulation of protein transport GO:0051223 3 0.043
hemopoiesis GO:0030097 183 0.043
modification dependent macromolecule catabolic process GO:0043632 3 0.042
vasculogenesis GO:0001570 41 0.042
epithelial cell fate commitment GO:0072148 11 0.042
regulation of cell proliferation GO:0042127 37 0.042
fin morphogenesis GO:0033334 53 0.042
Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.042
regulation of locomotion GO:0040012 55 0.042
hypochord development GO:0055016 3 0.042
ventral spinal cord interneuron differentiation GO:0021514 12 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.041
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.041
catabolic process GO:0009056 32 0.041
mesenchymal cell differentiation GO:0048762 87 0.041
regulation of protein targeting GO:1903533 2 0.041
modification dependent protein catabolic process GO:0019941 3 0.040
regulation of canonical wnt signaling pathway GO:0060828 34 0.039
myeloid cell differentiation GO:0030099 86 0.039
patterning of lymph vessels GO:0060854 1 0.039
muscle organ development GO:0007517 101 0.039
neuron migration GO:0001764 22 0.039
wound healing GO:0042060 90 0.038
tube closure GO:0060606 1 0.038
negative regulation of biological process GO:0048519 304 0.038
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.038
endothelial cell differentiation GO:0045446 20 0.038
protein modification process GO:0036211 100 0.038
dorsal aorta morphogenesis GO:0035912 3 0.038
response to nutrient GO:0007584 3 0.037
regulation of organelle organization GO:0033043 29 0.037
nephron development GO:0072006 31 0.037
Mouse
cardiac cell fate commitment GO:0060911 1 0.037
neuromast development GO:0048884 46 0.037
Zebrafish
apoptotic process involved in development GO:1902742 2 0.037
regulation of embryonic development GO:0045995 47 0.037
primitive erythrocyte differentiation GO:0060319 5 0.037
diencephalon development GO:0021536 58 0.037
photoreceptor cell differentiation GO:0046530 55 0.037
Zebrafish
spinal cord association neuron differentiation GO:0021527 1 0.036
otic placode formation GO:0043049 23 0.036
lymphatic endothelial cell differentiation GO:0060836 1 0.036
lamellipodium assembly GO:0030032 1 0.036
central nervous system myelin formation GO:0032289 1 0.036
auditory receptor cell fate commitment GO:0009912 4 0.036
heart formation GO:0060914 13 0.035
artery development GO:0060840 22 0.035
phosphate containing compound metabolic process GO:0006796 108 0.034
post embryonic morphogenesis GO:0009886 4 0.034
notch signaling pathway GO:0007219 35 0.034
negative regulation of cellular metabolic process GO:0031324 77 0.034
determination of heart left right asymmetry GO:0061371 117 0.034
oxoacid metabolic process GO:0043436 31 0.034
regulation of phosphorus metabolic process GO:0051174 43 0.034
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.034
cell cycle g1 s phase transition GO:0044843 1 0.034
muscle structure development GO:0061061 196 0.034
positive regulation of cell substrate adhesion GO:0010811 1 0.033
heart looping GO:0001947 94 0.032
ear morphogenesis GO:0042471 64 0.032
Zebrafish
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.032
brain morphogenesis GO:0048854 18 0.032
embryonic cranial skeleton morphogenesis GO:0048701 90 0.032
negative regulation of endothelial cell migration GO:0010596 1 0.032
notochord development GO:0030903 54 0.032
rhombomere 4 development GO:0021570 5 0.031
posterior lateral line neuromast development GO:0048919 20 0.031
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.031
sensory neuron axon guidance GO:0097374 3 0.031
cellular ketone metabolic process GO:0042180 11 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
tissue remodeling GO:0048771 4 0.031
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.031
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.031
Mouse
response to lipid GO:0033993 60 0.031
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.030
negative regulation of phosphate metabolic process GO:0045936 13 0.030
negative regulation of transcription dna templated GO:0045892 45 0.030
determination of dorsal ventral asymmetry GO:0048262 34 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.030
cell cell signaling GO:0007267 52 0.030
Worm
developmental process involved in reproduction GO:0003006 27 0.030
positive regulation of neural precursor cell proliferation GO:2000179 1 0.030
positive regulation of neuron death GO:1901216 1 0.030
photoreceptor cell fate commitment GO:0046552 1 0.029
response to wounding GO:0009611 116 0.029
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.029
heart valve morphogenesis GO:0003179 8 0.029
negative regulation of epithelial cell migration GO:0010633 1 0.029
regulation of stem cell proliferation GO:0072091 2 0.029
atrioventricular valve development GO:0003171 11 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.029
outflow tract morphogenesis GO:0003151 1 0.029
mesodermal cell fate specification GO:0007501 12 0.028
female sex differentiation GO:0046660 4 0.028
system process GO:0003008 185 0.028
pharyngeal system development GO:0060037 18 0.028
photoreceptor cell development GO:0042461 40 0.028
Zebrafish
regulation of biological quality GO:0065008 263 0.028
eye photoreceptor cell development GO:0042462 30 0.028
Zebrafish
phosphorus metabolic process GO:0006793 109 0.028
endothelium development GO:0003158 25 0.027
cell fate specification involved in pattern specification GO:0060573 3 0.027
positive regulation of programmed cell death GO:0043068 29 0.027
regulation of programmed cell death GO:0043067 101 0.027
cellular response to endogenous stimulus GO:0071495 68 0.027
optomotor response GO:0071632 1 0.027
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.027
gabaergic neuron differentiation GO:0097154 2 0.027
heart process GO:0003015 71 0.027
positive regulation of secretion by cell GO:1903532 1 0.026
multi organism process GO:0051704 134 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.026
heart valve formation GO:0003188 4 0.026
positive regulation of cell death GO:0010942 29 0.026
ameboidal type cell migration GO:0001667 143 0.026
endodermal cell fate specification GO:0001714 17 0.026
regulation of cell motility GO:2000145 46 0.026
protein complex subunit organization GO:0071822 46 0.026
regulation of erk1 and erk2 cascade GO:0070372 4 0.026
positive regulation of cellular biosynthetic process GO:0031328 68 0.026
pectoral fin development GO:0033339 50 0.026
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.025
single organism metabolic process GO:0044710 217 0.025
mechanosensory lateral line system development GO:0048881 49 0.025
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.025
otic vesicle development GO:0071599 42 0.025
regulation of nervous system development GO:0051960 90 0.025
Mouse
somitogenesis GO:0001756 87 0.025
protein metabolic process GO:0019538 183 0.025
positive regulation of secretion GO:0051047 1 0.025
negative regulation of cell adhesion GO:0007162 6 0.025
spinal cord motor neuron cell fate specification GO:0021520 8 0.025
regulation of axon extension involved in axon guidance GO:0048841 6 0.025
proximal distal pattern formation GO:0009954 1 0.025
Mouse
negative regulation of cytokine production GO:0001818 1 0.025
regulation of neuron migration GO:2001222 2 0.024
regulation of cell fate specification GO:0042659 20 0.024
cellular hormone metabolic process GO:0034754 19 0.024
aging GO:0007568 2 0.024
positive regulation of rna metabolic process GO:0051254 59 0.024
biological adhesion GO:0022610 40 0.024
forebrain neuron fate commitment GO:0021877 1 0.023
negative regulation of gliogenesis GO:0014014 1 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.023
ventral spinal cord interneuron specification GO:0021521 3 0.023
glomerulus development GO:0032835 27 0.023
neuroblast fate determination GO:0007400 1 0.023
regulation of cellular component movement GO:0051270 55 0.023
response to growth factor GO:0070848 39 0.023
regulation of endodermal cell fate specification GO:0042663 15 0.023
morphogenesis of an epithelial sheet GO:0002011 49 0.023
response to oxygen containing compound GO:1901700 55 0.023
regulation of cellular component size GO:0032535 30 0.023
negative regulation of collateral sprouting GO:0048671 2 0.023
positive regulation of gliogenesis GO:0014015 2 0.022
regulation of cysteine type endopeptidase activity GO:2000116 21 0.022
cellular response to growth factor stimulus GO:0071363 39 0.022
mechanoreceptor differentiation GO:0042490 37 0.022
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.022
cellular response to organic substance GO:0071310 105 0.022
spinal cord motor neuron differentiation GO:0021522 26 0.022
positive regulation of catabolic process GO:0009896 4 0.021
single organism nuclear import GO:1902593 3 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
embryonic heart tube morphogenesis GO:0003143 108 0.021
gtp catabolic process GO:0006184 2 0.021
positive regulation of cellular component organization GO:0051130 13 0.021
morphogenesis of embryonic epithelium GO:0016331 30 0.021
Mouse
positive regulation of signaling GO:0023056 56 0.021
cell migration involved in heart development GO:0060973 22 0.021
epithelial cell morphogenesis GO:0003382 2 0.021
stem cell fate determination GO:0048867 1 0.021
negative regulation of cell migration GO:0030336 17 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
organic substance catabolic process GO:1901575 28 0.021
regulation of cell migration GO:0030334 40 0.021
peptidyl lysine acetylation GO:0018394 2 0.020
biosynthetic process GO:0009058 294 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
Mouse
macromolecule modification GO:0043412 111 0.020
formation of primary germ layer GO:0001704 62 0.020
central nervous system neuron differentiation GO:0021953 74 0.020
Zebrafish
cytoskeleton organization GO:0007010 96 0.020
single organism organelle organization GO:1902589 199 0.020
maintenance of location GO:0051235 4 0.020
sprouting angiogenesis GO:0002040 53 0.020
endothelial cell development GO:0001885 12 0.020
pons development GO:0021548 11 0.020
endocrine system development GO:0035270 65 0.020
cell proliferation in midbrain GO:0033278 4 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.020
morphogenesis of an epithelial fold GO:0060571 1 0.019
cell migration in hindbrain GO:0021535 7 0.019
forebrain regionalization GO:0021871 4 0.019
response to external biotic stimulus GO:0043207 97 0.019
cellular response to external stimulus GO:0071496 2 0.019
positive regulation of biosynthetic process GO:0009891 68 0.019
retina layer formation GO:0010842 24 0.019
Zebrafish
negative regulation of rna biosynthetic process GO:1902679 45 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
artery morphogenesis GO:0048844 14 0.019

irx3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.024