Danio rerio

0 known processes

cd4-4

cd4-4 protein

(Aliases: CD4-3)

cd4-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 241 0.047
regulation of production of molecular mediator of immune response GO:0002700 1 0.047
leukocyte proliferation GO:0070661 1 0.044
response to external biotic stimulus GO:0043207 97 0.042
regulation of cytokine production GO:0001817 3 0.039
regulation of cell activation GO:0050865 1 0.038
larval development GO:0002164 2 0.037
mononuclear cell proliferation GO:0032943 1 0.035
signal transduction GO:0007165 455 0.035
response to biotic stimulus GO:0009607 97 0.033
aging GO:0007568 2 0.032
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.032
amine metabolic process GO:0009308 2 0.032
production of molecular mediator of immune response GO:0002440 2 0.032
cell surface receptor signaling pathway GO:0007166 325 0.031
response to other organism GO:0051707 97 0.030
positive regulation of transport GO:0051050 2 0.030
response to external stimulus GO:0009605 264 0.030
lymphocyte proliferation GO:0046651 1 0.030
immune system development GO:0002520 191 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
positive regulation of cell activation GO:0050867 1 0.028
phagocytosis GO:0006909 3 0.028
cellular amine metabolic process GO:0044106 2 0.028
maintenance of location GO:0051235 4 0.028
protein localization to nucleus GO:0034504 3 0.028
positive regulation of immune effector process GO:0002699 3 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
response to drug GO:0042493 3 0.027
positive regulation of cytokine production GO:0001819 2 0.027
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.027
peptidyl lysine acetylation GO:0018394 2 0.026
female sex differentiation GO:0046660 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.025
hemopoiesis GO:0030097 183 0.025
internal protein amino acid acetylation GO:0006475 2 0.025
cellular ketone metabolic process GO:0042180 11 0.025
response to stress GO:0006950 263 0.025
b cell activation GO:0042113 2 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
heterocycle metabolic process GO:0046483 290 0.025
regulation of response to stimulus GO:0048583 269 0.025
protein acetylation GO:0006473 2 0.024
regulation of protein transport GO:0051223 3 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
stem cell maintenance GO:0019827 4 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
positive regulation of map kinase activity GO:0043406 3 0.024
nuclear transport GO:0051169 4 0.024
positive regulation of catabolic process GO:0009896 4 0.024
tube morphogenesis GO:0035239 349 0.023
vasculature development GO:0001944 278 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
internal peptidyl lysine acetylation GO:0018393 2 0.023
regulation of protein catabolic process GO:0042176 1 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
meiotic cell cycle process GO:1903046 3 0.023
central nervous system development GO:0007417 387 0.022
lipid storage GO:0019915 1 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
ubiquitin dependent protein catabolic process GO:0006511 3 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
protein import into nucleus GO:0006606 3 0.021
meiotic nuclear division GO:0007126 4 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
positive regulation of cell cycle GO:0045787 3 0.021
nucleic acid templated transcription GO:0097659 181 0.021
blood vessel development GO:0001568 246 0.021
female gonad development GO:0008585 4 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
organic substance biosynthetic process GO:1901576 289 0.021
multicellular organism growth GO:0035264 4 0.021
regulation of signal transduction GO:0009966 225 0.021
protein acylation GO:0043543 3 0.020
regulation of inflammatory response GO:0050727 2 0.020
regulation of gene expression GO:0010468 265 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
head development GO:0060322 303 0.020
development of primary female sexual characteristics GO:0046545 4 0.020
brain development GO:0007420 293 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
single organism metabolic process GO:0044710 217 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
gene expression GO:0010467 252 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
cellular component movement GO:0006928 335 0.019
single organism nuclear import GO:1902593 3 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
protein targeting to nucleus GO:0044744 3 0.019
defense response GO:0006952 47 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
cell migration GO:0016477 237 0.019
atp catabolic process GO:0006200 4 0.019
rna biosynthetic process GO:0032774 181 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
cellular protein catabolic process GO:0044257 4 0.018
response to bacterium GO:0009617 58 0.018
cellular component morphogenesis GO:0032989 336 0.018
regulation of cell communication GO:0010646 232 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
nuclear import GO:0051170 3 0.018
blood vessel morphogenesis GO:0048514 216 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
embryonic organ development GO:0048568 381 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
oxoacid metabolic process GO:0043436 31 0.018
rna localization GO:0006403 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
organic acid metabolic process GO:0006082 31 0.018
positive regulation of biological process GO:0048518 253 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
angiogenesis GO:0001525 158 0.018
cell morphogenesis GO:0000902 289 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
response to chemical GO:0042221 320 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
regulation of primary metabolic process GO:0080090 311 0.017
b cell mediated immunity GO:0019724 3 0.017
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.017
small molecule metabolic process GO:0044281 77 0.017
cellular biosynthetic process GO:0044249 286 0.017
stem cell proliferation GO:0072089 4 0.017
positive regulation of leukocyte differentiation GO:1902107 1 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
phosphatidylinositol mediated signaling GO:0048015 2 0.017
regulation of biosynthetic process GO:0009889 250 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.017
protein secretion GO:0009306 1 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
regulation of protein complex assembly GO:0043254 3 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
biosynthetic process GO:0009058 294 0.016
transcription dna templated GO:0006351 181 0.016
regulation of biological quality GO:0065008 263 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
negative regulation of cytokine production GO:0001818 1 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
adult behavior GO:0030534 2 0.016
heart development GO:0007507 313 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
calcium ion transport into cytosol GO:0060402 3 0.016
amino acid transport GO:0006865 2 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
sensory perception of chemical stimulus GO:0007606 3 0.015
positive regulation of secretion GO:0051047 1 0.015
protein import GO:0017038 3 0.015
immune effector process GO:0002252 23 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
cellular response to external stimulus GO:0071496 2 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
gtp metabolic process GO:0046039 4 0.015
positive regulation of cellular process GO:0048522 201 0.015
regulation of blood pressure GO:0008217 1 0.015
regulation of autophagy GO:0010506 3 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
compound eye development GO:0048749 2 0.015
phagocytosis engulfment GO:0006911 1 0.015
leukocyte mediated cytotoxicity GO:0001909 1 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
response to carbohydrate GO:0009743 3 0.015
sleep GO:0030431 1 0.015
cytokinesis GO:0000910 3 0.015
protein heterooligomerization GO:0051291 1 0.015
immunoglobulin mediated immune response GO:0016064 3 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of signaling GO:0023051 235 0.015
negative regulation of secretion GO:0051048 2 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
single organism localization GO:1902578 225 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
positive regulation of leukocyte mediated immunity GO:0002705 1 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
regulation of binding GO:0051098 3 0.015
regulation of hormone secretion GO:0046883 2 0.015
regulation of metal ion transport GO:0010959 4 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
rna metabolic process GO:0016070 219 0.015
regulation of transcription dna templated GO:0006355 213 0.015
sequestering of metal ion GO:0051238 3 0.014
regulation of dna recombination GO:0000018 2 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
cell part morphogenesis GO:0032990 246 0.014
specification of symmetry GO:0009799 204 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
antimicrobial humoral response GO:0019730 2 0.014
membrane invagination GO:0010324 1 0.014
nucleic acid metabolic process GO:0090304 244 0.014
regulation of metabolic process GO:0019222 359 0.014
endocrine process GO:0050886 2 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
autophagy GO:0006914 4 0.014
meiotic chromosome segregation GO:0045132 3 0.014
neurotransmitter transport GO:0006836 2 0.014
mitochondrion organization GO:0007005 4 0.014
negative regulation of protein transport GO:0051224 3 0.014
system process GO:0003008 185 0.014
locomotion GO:0040011 313 0.014
neuron differentiation GO:0030182 353 0.014
cognition GO:0050890 1 0.014
localization of cell GO:0051674 244 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
translational initiation GO:0006413 3 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of cell shape GO:0008360 1 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
positive regulation of inflammatory response GO:0050729 1 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
transport GO:0006810 220 0.014
interspecies interaction between organisms GO:0044419 4 0.014
muscle structure development GO:0061061 196 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of translational initiation GO:0006446 1 0.014
regulation of rna biosynthetic process GO:2001141 213 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of synapse assembly GO:0051963 3 0.013
cellular amide metabolic process GO:0043603 4 0.013
tissue remodeling GO:0048771 4 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
multi organism process GO:0051704 134 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
regulation of endocrine process GO:0044060 2 0.013
cellular component biogenesis GO:0044085 178 0.013
protein localization to plasma membrane GO:0072659 1 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
negative regulation of biological process GO:0048519 304 0.013
regulation of muscle contraction GO:0006937 3 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
protein polymerization GO:0051258 4 0.013
hormone secretion GO:0046879 2 0.013
sensory organ development GO:0007423 393 0.013
cell killing GO:0001906 2 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
generation of neurons GO:0048699 385 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
cellular component disassembly GO:0022411 1 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
regionalization GO:0003002 274 0.013
anterior posterior pattern specification GO:0009952 152 0.013
immune response GO:0006955 28 0.013
neurotransmitter secretion GO:0007269 2 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
protein complex disassembly GO:0043241 1 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
nuclear export GO:0051168 1 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
immunoglobulin production GO:0002377 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
cell motility GO:0048870 244 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
regulation of organelle assembly GO:1902115 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
protein homooligomerization GO:0051260 3 0.012
adherens junction organization GO:0034332 4 0.012
single organism organelle organization GO:1902589 199 0.012
cellular response to starvation GO:0009267 1 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
activation of immune response GO:0002253 9 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
chordate embryonic development GO:0043009 271 0.012
spermatid development GO:0007286 2 0.012
somatic muscle development GO:0007525 4 0.012
positive regulation of reproductive process GO:2000243 2 0.012
gtp catabolic process GO:0006184 2 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
eye development GO:0001654 277 0.012
hormone transport GO:0009914 2 0.012
response to organic substance GO:0010033 153 0.012
protein stabilization GO:0050821 2 0.012
positive regulation of histone modification GO:0031058 1 0.012
regulation of synapse organization GO:0050807 3 0.012
negative regulation of defense response GO:0031348 2 0.012
establishment of localization GO:0051234 244 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
sensory organ morphogenesis GO:0090596 200 0.012
single organism transport GO:0044765 206 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
secondary metabolic process GO:0019748 3 0.012
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.012
toll like receptor signaling pathway GO:0002224 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
cell projection organization GO:0030030 284 0.012
regulation of natural killer cell mediated immunity GO:0002715 1 0.012
neuron development GO:0048666 262 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
intracellular signal transduction GO:0035556 85 0.011
carbohydrate homeostasis GO:0033500 1 0.011
regulation of sodium ion transport GO:0002028 2 0.011
positive regulation of cell killing GO:0031343 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
peptide transport GO:0015833 1 0.011
sequestering of calcium ion GO:0051208 3 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
activation of mapk activity GO:0000187 3 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
regulation of transporter activity GO:0032409 2 0.011
olfactory lobe development GO:0021988 4 0.011
regulation of rna metabolic process GO:0051252 224 0.011
response to hexose GO:0009746 3 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
ameboidal type cell migration GO:0001667 143 0.011
single fertilization GO:0007338 3 0.011
actin filament based movement GO:0030048 1 0.011
rna transport GO:0050658 2 0.011
somitogenesis GO:0001756 87 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
intracellular mrna localization GO:0008298 1 0.011
spermatid differentiation GO:0048515 2 0.011
regulation of dna replication GO:0006275 3 0.011
endocrine hormone secretion GO:0060986 2 0.011
positive regulation of translation GO:0045727 1 0.011
regulation of tube size GO:0035150 2 0.011
stem cell fate commitment GO:0048865 1 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
developmental programmed cell death GO:0010623 4 0.011
post embryonic organ development GO:0048569 4 0.011
regulation of leukocyte mediated immunity GO:0002703 1 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
protein metabolic process GO:0019538 183 0.011
complement activation GO:0006956 3 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of protein targeting GO:1903533 2 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
camera type eye development GO:0043010 222 0.011
detection of chemical stimulus GO:0009593 4 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
muscle cell differentiation GO:0042692 139 0.011
response to uv GO:0009411 3 0.011
leukocyte differentiation GO:0002521 25 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
cellular component assembly GO:0022607 170 0.010
digestive system development GO:0055123 289 0.010
regulation of developmental process GO:0050793 247 0.010
response to corticosteroid GO:0031960 1 0.010
retina development in camera type eye GO:0060041 146 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
somatic cell dna recombination GO:0016444 1 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
cellular response to radiation GO:0071478 4 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
endosomal transport GO:0016197 2 0.010
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.010
growth GO:0040007 174 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of immune system process GO:0002682 34 0.010
lateral inhibition GO:0046331 1 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
gastrulation GO:0007369 208 0.010
catechol containing compound metabolic process GO:0009712 2 0.010
regulation of systemic arterial blood pressure GO:0003073 1 0.010
positive regulation of notch signaling pathway GO:0045747 3 0.010

cd4-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
musculoskeletal system disease DOID:17 0 0.024
nervous system disease DOID:863 0 0.019
muscular disease DOID:0080000 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
muscle tissue disease DOID:66 0 0.011
organ system cancer DOID:0050686 0 0.011
myopathy DOID:423 0 0.011