Danio rerio

0 known processes

slc25a22

solute carrier family 25 (mitochondrial carrier: glutamate), member 22

(Aliases: zgc:56592,sb:cb229,wu:fb72h03,wu:fa12h05)

slc25a22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular metabolic process GO:0031323 320 0.491
cellular nitrogen compound metabolic process GO:0034641 290 0.329
Yeast
positive regulation of cellular process GO:0048522 201 0.219
regulation of macromolecule metabolic process GO:0060255 317 0.195
signal transduction GO:0007165 455 0.168
lipid storage GO:0019915 1 0.161
Worm
regulation of signal transduction GO:0009966 225 0.149
heterocycle metabolic process GO:0046483 290 0.137
regulation of primary metabolic process GO:0080090 311 0.134
positive regulation of cellular catabolic process GO:0031331 3 0.121
ameboidal type cell migration GO:0001667 143 0.121
establishment of localization GO:0051234 244 0.120
Yeast
negative regulation of cellular process GO:0048523 283 0.120
larval development GO:0002164 2 0.118
cellular macromolecule metabolic process GO:0044260 391 0.115
regulation of signaling GO:0023051 235 0.115
negative regulation of signaling GO:0023057 96 0.113
cognition GO:0050890 1 0.112
nucleobase containing compound metabolic process GO:0006139 274 0.111
regulation of metabolic process GO:0019222 359 0.109
locomotion GO:0040011 313 0.105
positive regulation of biological process GO:0048518 253 0.103
gene expression GO:0010467 252 0.103
organic substance biosynthetic process GO:1901576 289 0.101
adherens junction organization GO:0034332 4 0.099
nitrogen compound metabolic process GO:0006807 319 0.099
Yeast
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.095
actin filament based process GO:0030029 64 0.091
regulation of multicellular organismal development GO:2000026 223 0.090
cellular macromolecule biosynthetic process GO:0034645 224 0.090
regulation of rna biosynthetic process GO:2001141 213 0.085
regulation of gene expression GO:0010468 265 0.085
regulation of cell communication GO:0010646 232 0.083
regulation of cell death GO:0010941 103 0.081
regulation of erk1 and erk2 cascade GO:0070372 4 0.081
regulation of cell development GO:0060284 100 0.080
nuclear transport GO:0051169 4 0.077
cellular component assembly GO:0022607 170 0.077
cell cycle g1 s phase transition GO:0044843 1 0.075
organic cyclic compound biosynthetic process GO:1901362 223 0.074
maintenance of location GO:0051235 4 0.072
Worm
regulation of apoptotic process GO:0042981 98 0.070
regulation of protein transport GO:0051223 3 0.068
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.068
regulation of response to stimulus GO:0048583 269 0.067
death GO:0016265 121 0.067
cellular nitrogen compound biosynthetic process GO:0044271 218 0.066
Yeast
regulation of cell differentiation GO:0045595 142 0.066
regulation of transcription dna templated GO:0006355 213 0.066
regulation of cellular biosynthetic process GO:0031326 245 0.065
aromatic compound biosynthetic process GO:0019438 217 0.064
intracellular signal transduction GO:0035556 85 0.063
cellular component biogenesis GO:0044085 178 0.063
regulation of macromolecule biosynthetic process GO:0010556 225 0.062
small molecule metabolic process GO:0044281 77 0.062
transport GO:0006810 220 0.062
Yeast
nucleocytoplasmic transport GO:0006913 4 0.061
positive regulation of catabolic process GO:0009896 4 0.060
cellular response to external stimulus GO:0071496 2 0.060
cell morphogenesis GO:0000902 289 0.059
g1 s transition of mitotic cell cycle GO:0000082 1 0.058
regulation of multicellular organismal process GO:0051239 277 0.058
regulation of rna metabolic process GO:0051252 224 0.058
protein stabilization GO:0050821 2 0.058
embryo development ending in birth or egg hatching GO:0009792 271 0.058
organelle organization GO:0006996 227 0.057
transcription dna templated GO:0006351 181 0.056
multi organism process GO:0051704 134 0.056
cellular biosynthetic process GO:0044249 286 0.055
Yeast
positive regulation of transport GO:0051050 2 0.055
regulation of nucleotide catabolic process GO:0030811 2 0.055
extrinsic apoptotic signaling pathway GO:0097191 3 0.053
cellular modified amino acid metabolic process GO:0006575 3 0.053
positive regulation of cellular component biogenesis GO:0044089 3 0.053
negative regulation of cell communication GO:0010648 96 0.052
regulation of biosynthetic process GO:0009889 250 0.052
cellular aromatic compound metabolic process GO:0006725 295 0.051
phosphorus metabolic process GO:0006793 109 0.049
cell death GO:0008219 121 0.049
cellular ketone metabolic process GO:0042180 11 0.049
cellular amine metabolic process GO:0044106 2 0.048
biosynthetic process GO:0009058 294 0.048
Yeast
negative regulation of protein transport GO:0051224 3 0.048
macromolecule biosynthetic process GO:0009059 227 0.048
regulation of cell adhesion GO:0030155 15 0.048
phosphorylation GO:0016310 69 0.047
regulation of biological quality GO:0065008 263 0.047
Worm
actin cytoskeleton organization GO:0030036 63 0.047
nucleic acid templated transcription GO:0097659 181 0.047
regulation of developmental process GO:0050793 247 0.047
phagocytosis engulfment GO:0006911 1 0.047
gastrulation GO:0007369 208 0.046
regulation of synapse organization GO:0050807 3 0.046
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.046
protein modification process GO:0036211 100 0.046
meiotic nuclear division GO:0007126 4 0.045
single organism metabolic process GO:0044710 217 0.045
heart development GO:0007507 313 0.044
regulation of locomotion GO:0040012 55 0.044
establishment of protein localization to organelle GO:0072594 4 0.044
cellular protein catabolic process GO:0044257 4 0.042
negative regulation of response to stimulus GO:0048585 104 0.042
nucleic acid metabolic process GO:0090304 244 0.042
erk1 and erk2 cascade GO:0070371 4 0.042
synaptic growth at neuromuscular junction GO:0051124 2 0.042
cell projection organization GO:0030030 284 0.042
protein import into nucleus GO:0006606 3 0.042
protein import GO:0017038 3 0.042
negative regulation of nuclear division GO:0051784 3 0.041
amine metabolic process GO:0009308 2 0.041
mitotic cell cycle process GO:1903047 48 0.040
heterocycle biosynthetic process GO:0018130 215 0.040
regulation of establishment of protein localization GO:0070201 4 0.040
cellular response to nutrient levels GO:0031669 2 0.038
rna metabolic process GO:0016070 219 0.038
digestive tract morphogenesis GO:0048546 231 0.038
positive regulation of cell adhesion GO:0045785 1 0.038
mitotic cell cycle GO:0000278 64 0.037
regulation of nucleoside metabolic process GO:0009118 2 0.037
positive regulation of metabolic process GO:0009893 108 0.037
muscle cell development GO:0055001 115 0.036
nuclear import GO:0051170 3 0.036
protein metabolic process GO:0019538 183 0.036
muscle structure development GO:0061061 196 0.036
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.035
regulation of purine nucleotide catabolic process GO:0033121 2 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
positive regulation of cell cycle GO:0045787 3 0.034
cell proliferation GO:0008283 80 0.034
cell surface receptor signaling pathway GO:0007166 325 0.034
keratinocyte differentiation GO:0030216 0 0.034
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.034
cellular protein metabolic process GO:0044267 129 0.034
negative regulation of epithelial cell proliferation GO:0050680 1 0.034
convergent extension GO:0060026 118 0.033
stem cell maintenance GO:0019827 4 0.033
phosphate containing compound metabolic process GO:0006796 108 0.033
nucleobase containing compound biosynthetic process GO:0034654 205 0.033
macromolecule localization GO:0033036 54 0.033
Worm
nuclear division GO:0000280 23 0.033
meiotic cell cycle process GO:1903046 3 0.032
cell morphogenesis involved in differentiation GO:0000904 195 0.032
cellular component movement GO:0006928 335 0.032
protein targeting to nucleus GO:0044744 3 0.032
positive regulation of nucleoside metabolic process GO:0045979 1 0.032
cellular response to extracellular stimulus GO:0031668 2 0.032
negative regulation of cell death GO:0060548 60 0.032
alternative mrna splicing via spliceosome GO:0000380 1 0.032
cellular amino acid metabolic process GO:0006520 7 0.031
cell projection assembly GO:0030031 64 0.031
regulation of chromosome segregation GO:0051983 1 0.031
tube morphogenesis GO:0035239 349 0.031
cell fate commitment GO:0045165 99 0.031
skin development GO:0043588 54 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
single organism nuclear import GO:1902593 3 0.030
regulation of intracellular signal transduction GO:1902531 57 0.030
cell migration GO:0016477 237 0.030
programmed cell death GO:0012501 119 0.030
spermatid development GO:0007286 2 0.030
aging GO:0007568 2 0.029
response to vitamin GO:0033273 3 0.029
regulation of protein metabolic process GO:0051246 56 0.029
cellular protein modification process GO:0006464 100 0.029
embryonic organ development GO:0048568 381 0.029
multicellular organism growth GO:0035264 4 0.029
membrane invagination GO:0010324 1 0.028
epithelial cell differentiation GO:0030855 116 0.028
regulation of epithelial cell proliferation GO:0050678 3 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
mesoderm development GO:0007498 88 0.028
regulation of reproductive process GO:2000241 4 0.028
negative regulation of signal transduction GO:0009968 94 0.027
regulation of embryonic development GO:0045995 47 0.027
regulation of catalytic activity GO:0050790 55 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
single organism localization GO:1902578 225 0.027
Yeast
cytokinesis GO:0000910 3 0.027
negative regulation of developmental process GO:0051093 65 0.027
negative regulation of apoptotic process GO:0043066 55 0.027
growth GO:0040007 174 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
digestive tract development GO:0048565 265 0.026
organism emergence from protective structure GO:0071684 4 0.026
negative regulation of cell differentiation GO:0045596 46 0.025
positive regulation of nucleotide catabolic process GO:0030813 1 0.025
macromolecule modification GO:0043412 111 0.025
gtp metabolic process GO:0046039 4 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
negative regulation of mapk cascade GO:0043409 4 0.025
regulation of mitotic cell cycle GO:0007346 25 0.025
cellular component morphogenesis GO:0032989 336 0.025
spermatid differentiation GO:0048515 2 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.024
apoptotic process GO:0006915 116 0.024
positive regulation of programmed cell death GO:0043068 29 0.024
phagocytosis GO:0006909 3 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
localization of cell GO:0051674 244 0.024
cellular component disassembly GO:0022411 1 0.024
negative regulation of programmed cell death GO:0043069 58 0.023
regulation of inflammatory response GO:0050727 2 0.023
regulation of programmed cell death GO:0043067 101 0.023
developmental growth GO:0048589 166 0.023
protein secretion GO:0009306 1 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
digestive system development GO:0055123 289 0.023
homeostatic process GO:0042592 142 0.022
protein localization to nucleus GO:0034504 3 0.022
striated muscle tissue development GO:0014706 110 0.022
regulation of autophagy GO:0010506 3 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
oxoacid metabolic process GO:0043436 31 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
cell projection morphogenesis GO:0048858 244 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
cytoskeleton organization GO:0007010 96 0.022
single organism organelle organization GO:1902589 199 0.021
regulation of cytokine production GO:0001817 3 0.021
regulation of protein complex assembly GO:0043254 3 0.021
system process GO:0003008 185 0.021
positive regulation of response to stimulus GO:0048584 80 0.021
cell substrate adhesion GO:0031589 4 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
rna biosynthetic process GO:0032774 181 0.021
regulation of multicellular organism growth GO:0040014 4 0.020
epidermis development GO:0008544 48 0.020
carbohydrate derivative metabolic process GO:1901135 61 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
spindle assembly GO:0051225 2 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
secondary metabolic process GO:0019748 3 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
regulation of blood pressure GO:0008217 1 0.020
gtp catabolic process GO:0006184 2 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
positive regulation of apoptotic process GO:0043065 29 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
regulation of synapse assembly GO:0051963 3 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
stem cell development GO:0048864 82 0.019
circulatory system process GO:0003013 87 0.019
cell part morphogenesis GO:0032990 246 0.019
epithelium migration GO:0090132 25 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
negative regulation of cell adhesion GO:0007162 6 0.018
adherens junction assembly GO:0034333 1 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
positive regulation of ras protein signal transduction GO:0046579 1 0.018
organic acid metabolic process GO:0006082 31 0.018
apoptotic signaling pathway GO:0097190 23 0.018
cell migration involved in gastrulation GO:0042074 79 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
regulation of cellular protein metabolic process GO:0032268 52 0.017
single organism biosynthetic process GO:0044711 71 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
regulation of cell shape GO:0008360 1 0.017
catabolic process GO:0009056 32 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
mitotic nuclear division GO:0007067 18 0.017
regulation of phosphate metabolic process GO:0019220 43 0.017
regulation of actin filament based movement GO:1903115 1 0.017
positive regulation of cell activation GO:0050867 1 0.017
nerve development GO:0021675 45 0.017
spindle assembly involved in meiosis GO:0090306 1 0.017
response to stress GO:0006950 263 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
regulation of binding GO:0051098 3 0.017
muscle tissue development GO:0060537 110 0.017
regulation of organ morphogenesis GO:2000027 35 0.017
alpha amino acid metabolic process GO:1901605 3 0.017
immune system process GO:0002376 241 0.016
negative regulation of defense response GO:0031348 2 0.016
regulation of mitotic cell cycle phase transition GO:1901990 8 0.016
negative regulation of cytokine production GO:0001818 1 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
vesicle mediated transport GO:0016192 22 0.016
cortical cytoskeleton organization GO:0030865 1 0.016
hatching GO:0035188 4 0.016
organic substance catabolic process GO:1901575 28 0.016
regulation of dendrite development GO:0050773 3 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
protein localization GO:0008104 40 0.016
positive regulation of gtpase activity GO:0043547 1 0.016
regulation of mrna processing GO:0050684 3 0.016
cell matrix adhesion GO:0007160 4 0.016
establishment of localization in cell GO:0051649 77 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.015
blood circulation GO:0008015 87 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
ras protein signal transduction GO:0007265 7 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
meiotic spindle organization GO:0000212 1 0.015
cell fate specification GO:0001708 68 0.015
negative regulation of biological process GO:0048519 304 0.015
epidermal cell differentiation GO:0009913 36 0.015
startle response GO:0001964 4 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
stem cell proliferation GO:0072089 4 0.015
skeletal muscle tissue development GO:0007519 67 0.015
fatty acid biosynthetic process GO:0006633 4 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
cell cycle process GO:0022402 53 0.015
regulation of muscle contraction GO:0006937 3 0.015
neuron projection morphogenesis GO:0048812 161 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
negative regulation of mitosis GO:0045839 3 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
positive regulation of protein metabolic process GO:0051247 23 0.014
actin mediated cell contraction GO:0070252 1 0.014
vasculature development GO:0001944 278 0.014
mrna transport GO:0051028 2 0.014
specification of symmetry GO:0009799 204 0.014
meiosis i GO:0007127 1 0.014
developmental process involved in reproduction GO:0003006 27 0.014
regulation of protein catabolic process GO:0042176 1 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.014
macromolecule catabolic process GO:0009057 15 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
protein phosphorylation GO:0006468 47 0.014
single organism transport GO:0044765 206 0.014
Yeast
regulation of cellular component movement GO:0051270 55 0.014
heart morphogenesis GO:0003007 156 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
tissue migration GO:0090130 37 0.014
proteolysis GO:0006508 38 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.013
actin filament organization GO:0007015 15 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
positive regulation of cell death GO:0010942 29 0.013
regulation of molecular function GO:0065009 70 0.013
meiotic chromosome segregation GO:0045132 3 0.013
primitive hemopoiesis GO:0060215 27 0.013
positive regulation of secretion GO:0051047 1 0.013
oocyte maturation GO:0001556 4 0.013
response to nutrient GO:0007584 3 0.013
negative regulation of protein kinase b signaling GO:0051898 2 0.013
determination of left right symmetry GO:0007368 179 0.013
cartilage condensation GO:0001502 3 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
membrane lipid biosynthetic process GO:0046467 2 0.013
regulation of cell activation GO:0050865 1 0.013
neuroblast differentiation GO:0014016 1 0.013
negative regulation of secretion by cell GO:1903531 2 0.012
germ line stem cell maintenance GO:0030718 2 0.012
regulation of membrane potential GO:0042391 23 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
response to external stimulus GO:0009605 264 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
cell cycle GO:0007049 93 0.012
regionalization GO:0003002 274 0.012
regulation of cell migration GO:0030334 40 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
cellular localization GO:0051641 97 0.012
tissue remodeling GO:0048771 4 0.012
cranial nerve development GO:0021545 42 0.012
cellular response to starvation GO:0009267 1 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
head development GO:0060322 303 0.012
muscle contraction GO:0006936 18 0.012
sensory organ development GO:0007423 393 0.012
regulation of protein polymerization GO:0032271 2 0.012
inner ear receptor stereocilium organization GO:0060122 8 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
multicellular organismal signaling GO:0035637 22 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
axon development GO:0061564 166 0.011
endothelial cell migration GO:0043542 19 0.011
heart process GO:0003015 71 0.011
negative regulation of metabolic process GO:0009892 86 0.011
generation of neurons GO:0048699 385 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
regulation of protein targeting GO:1903533 2 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
liver development GO:0001889 96 0.011
negative regulation of cell cycle GO:0045786 14 0.011
regulation of gtpase activity GO:0043087 2 0.011
single organism intracellular transport GO:1902582 25 0.011
negative regulation of gene expression GO:0010629 65 0.011
stem cell differentiation GO:0048863 117 0.011
actin filament polymerization GO:0030041 2 0.011
endomembrane system organization GO:0010256 13 0.011
posttranscriptional regulation of gene expression GO:0010608 14 0.011
protein localization to plasma membrane GO:0072659 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
female meiotic division GO:0007143 2 0.011
nuclear migration GO:0007097 3 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
protein kinase b signaling GO:0043491 9 0.011
response to wounding GO:0009611 116 0.010
blood vessel morphogenesis GO:0048514 216 0.010
rna 3 end processing GO:0031123 2 0.010
regulation of phosphorylation GO:0042325 26 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
regulation of neurogenesis GO:0050767 87 0.010
regulation of jak stat cascade GO:0046425 3 0.010
gamete generation GO:0007276 33 0.010
chordate embryonic development GO:0043009 271 0.010
mesenchyme development GO:0060485 127 0.010
response to drug GO:0042493 3 0.010
epithelial cell morphogenesis GO:0003382 2 0.010

slc25a22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.168
muscular disease DOID:0080000 0 0.045
musculoskeletal system disease DOID:17 0 0.045
myopathy DOID:423 0 0.036
muscle tissue disease DOID:66 0 0.036
heart disease DOID:114 0 0.031
cardiomyopathy DOID:0050700 0 0.031
cardiovascular system disease DOID:1287 0 0.031
intrinsic cardiomyopathy DOID:0060036 0 0.023
nervous system disease DOID:863 0 0.019
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011