Danio rerio

0 known processes

derl1

Der1-like domain family, member 1

(Aliases: wu:fb09d07,wu:fb94d05,wu:fj92g12,zgc:55637)

derl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.317
establishment of localization GO:0051234 244 0.217
Human
tube morphogenesis GO:0035239 349 0.209
embryonic organ development GO:0048568 381 0.189
morphogenesis of an epithelium GO:0002009 333 0.176
regulation of biological quality GO:0065008 263 0.166
determination of bilateral symmetry GO:0009855 204 0.130
regulation of macromolecule metabolic process GO:0060255 317 0.123
regulation of multicellular organismal development GO:2000026 223 0.118
cellular response to external stimulus GO:0071496 2 0.114
transport GO:0006810 220 0.102
Human
positive regulation of transport GO:0051050 2 0.098
multicellular organism growth GO:0035264 4 0.098
biosynthetic process GO:0009058 294 0.093
synaptic growth at neuromuscular junction GO:0051124 2 0.089
heart morphogenesis GO:0003007 156 0.088
regulation of establishment of protein localization GO:0070201 4 0.086
phagocytosis GO:0006909 3 0.085
establishment of protein localization to plasma membrane GO:0090002 1 0.084
negative regulation of catabolic process GO:0009895 3 0.082
er to golgi vesicle mediated transport GO:0006888 1 0.082
single organism localization GO:1902578 225 0.079
Human
specification of symmetry GO:0009799 204 0.075
cellular response to nutrient levels GO:0031669 2 0.074
gtp metabolic process GO:0046039 4 0.074
embryo development ending in birth or egg hatching GO:0009792 271 0.073
single organism metabolic process GO:0044710 217 0.073
organelle organization GO:0006996 227 0.071
ubiquitin dependent protein catabolic process GO:0006511 3 0.071
Human
tube closure GO:0060606 1 0.070
determination of left right symmetry GO:0007368 179 0.070
organonitrogen compound metabolic process GO:1901564 74 0.067
guanosine containing compound catabolic process GO:1901069 2 0.067
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.066
Human
apoptotic process GO:0006915 116 0.065
cellular response to extracellular stimulus GO:0031668 2 0.063
embryonic heart tube morphogenesis GO:0003143 108 0.062
response to drug GO:0042493 3 0.062
regulation of primary metabolic process GO:0080090 311 0.060
organic substance transport GO:0071702 58 0.060
Human
chordate embryonic development GO:0043009 271 0.059
cellular response to starvation GO:0009267 1 0.059
growth GO:0040007 174 0.059
digestive system development GO:0055123 289 0.057
guanosine containing compound metabolic process GO:1901068 4 0.057
regulation of multicellular organism growth GO:0040014 4 0.057
cellular protein catabolic process GO:0044257 4 0.056
Human
protein secretion GO:0009306 1 0.056
epithelial tube morphogenesis GO:0060562 148 0.056
regulation of metabolic process GO:0019222 359 0.056
cellular macromolecule metabolic process GO:0044260 391 0.055
Human
cellular component morphogenesis GO:0032989 336 0.055
macromolecule biosynthetic process GO:0009059 227 0.055
single organism transport GO:0044765 206 0.053
Human
somitogenesis GO:0001756 87 0.053
maintenance of location GO:0051235 4 0.053
regulation of purine nucleotide catabolic process GO:0033121 2 0.052
somite development GO:0061053 96 0.052
cell morphogenesis GO:0000902 289 0.051
autophagy GO:0006914 4 0.051
multi organism cellular process GO:0044764 2 0.050
regulation of nucleotide catabolic process GO:0030811 2 0.050
regulation of cell shape GO:0008360 1 0.049
modification dependent macromolecule catabolic process GO:0043632 3 0.049
Human
regulation of protein catabolic process GO:0042176 1 0.048
negative regulation of biological process GO:0048519 304 0.048
immune system process GO:0002376 241 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
regulation of cell communication GO:0010646 232 0.048
purine nucleoside monophosphate catabolic process GO:0009128 4 0.047
hormone transport GO:0009914 2 0.047
positive regulation of biological process GO:0048518 253 0.047
positive regulation of secretion by cell GO:1903532 1 0.046
small molecule metabolic process GO:0044281 77 0.046
cellular biosynthetic process GO:0044249 286 0.046
multi organism process GO:0051704 134 0.045
regulation of cytoplasmic transport GO:1903649 4 0.045
digestive tract morphogenesis GO:0048546 231 0.044
response to biotic stimulus GO:0009607 97 0.044
central nervous system development GO:0007417 387 0.043
cellular localization GO:0051641 97 0.043
Human
gtp catabolic process GO:0006184 2 0.041
lipid storage GO:0019915 1 0.041
protein metabolic process GO:0019538 183 0.041
Human
regulation of apoptotic process GO:0042981 98 0.041
embryonic heart tube development GO:0035050 133 0.040
organic substance biosynthetic process GO:1901576 289 0.039
positive regulation of apoptotic signaling pathway GO:2001235 1 0.039
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.039
positive regulation of cellular component biogenesis GO:0044089 3 0.039
heart looping GO:0001947 94 0.038
positive regulation of cell cycle GO:0045787 3 0.038
regulation of cellular metabolic process GO:0031323 320 0.038
negative regulation of cellular process GO:0048523 283 0.038
single organism membrane fusion GO:0044801 2 0.038
heterocycle metabolic process GO:0046483 290 0.037
cellular amine metabolic process GO:0044106 2 0.037
cellular nitrogen compound metabolic process GO:0034641 290 0.037
response to carbohydrate GO:0009743 3 0.037
regulation of developmental process GO:0050793 247 0.036
ribonucleoside monophosphate catabolic process GO:0009158 4 0.036
regulation of nucleoside metabolic process GO:0009118 2 0.036
response to stress GO:0006950 263 0.036
Human
gastrulation GO:0007369 208 0.036
sensory organ development GO:0007423 393 0.036
adult behavior GO:0030534 2 0.035
macroautophagy GO:0016236 1 0.035
positive regulation of catabolic process GO:0009896 4 0.035
programmed cell death GO:0012501 119 0.035
death GO:0016265 121 0.035
intracellular transport GO:0046907 32 0.035
Human
protein localization to nucleus GO:0034504 3 0.034
atp catabolic process GO:0006200 4 0.034
modification dependent protein catabolic process GO:0019941 3 0.034
Human
organelle fusion GO:0048284 3 0.034
regulation of gtp catabolic process GO:0033124 2 0.033
carbohydrate derivative metabolic process GO:1901135 61 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.033
Human
regulation of hormone secretion GO:0046883 2 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
brain development GO:0007420 293 0.032
regulation of synapse organization GO:0050807 3 0.032
cellular aromatic compound metabolic process GO:0006725 295 0.032
hormone secretion GO:0046879 2 0.031
positive regulation of secretion GO:0051047 1 0.031
response to monosaccharide GO:0034284 3 0.031
apoptotic process involved in development GO:1902742 2 0.031
cell projection organization GO:0030030 284 0.031
response to external biotic stimulus GO:0043207 97 0.031
protein localization to plasma membrane GO:0072659 1 0.031
protein stabilization GO:0050821 2 0.030
negative regulation of cellular catabolic process GO:0031330 3 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.030
organic cyclic compound metabolic process GO:1901360 301 0.029
regulation of dendrite development GO:0050773 3 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.029
response to bacterium GO:0009617 58 0.029
regulation of protein transport GO:0051223 3 0.029
regulation of signaling GO:0023051 235 0.029
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
positive regulation of cellular process GO:0048522 201 0.028
cell substrate adhesion GO:0031589 4 0.028
peptide transport GO:0015833 1 0.028
positive regulation of metabolic process GO:0009893 108 0.028
regulation of protein metabolic process GO:0051246 56 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
regulation of metal ion transport GO:0010959 4 0.028
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.027
regulation of cytokine production GO:0001817 3 0.027
cellular component assembly GO:0022607 170 0.026
response to other organism GO:0051707 97 0.026
amine metabolic process GO:0009308 2 0.026
determination of heart left right asymmetry GO:0061371 117 0.026
golgi vesicle transport GO:0048193 3 0.025
meiotic chromosome segregation GO:0045132 3 0.025
purine containing compound metabolic process GO:0072521 29 0.025
regulation of binding GO:0051098 3 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.025
neuron differentiation GO:0030182 353 0.025
regulation of cellular component organization GO:0051128 86 0.025
regulation of signal transduction GO:0009966 225 0.025
regulation of gtpase activity GO:0043087 2 0.025
positive regulation of dna metabolic process GO:0051054 1 0.025
regulation of synapse assembly GO:0051963 3 0.025
regulation of protein complex assembly GO:0043254 3 0.024
head development GO:0060322 303 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
cilium morphogenesis GO:0060271 85 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
protein targeting to membrane GO:0006612 1 0.024
tissue remodeling GO:0048771 4 0.023
anterior posterior pattern specification GO:0009952 152 0.023
signal transduction GO:0007165 455 0.023
Human
aging GO:0007568 2 0.023
cell death GO:0008219 121 0.023
protein targeting to nucleus GO:0044744 3 0.023
regionalization GO:0003002 274 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
meiotic cell cycle process GO:1903046 3 0.023
single organism biosynthetic process GO:0044711 71 0.023
nucleobase containing small molecule metabolic process GO:0055086 32 0.023
establishment of protein localization to organelle GO:0072594 4 0.022
nucleoside monophosphate catabolic process GO:0009125 4 0.022
embryonic pattern specification GO:0009880 44 0.022
cell projection morphogenesis GO:0048858 244 0.022
nucleotide metabolic process GO:0009117 28 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
establishment of localization in cell GO:0051649 77 0.022
Human
regulation of hydrolase activity GO:0051336 28 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
viral process GO:0016032 1 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
Human
carbohydrate homeostasis GO:0033500 1 0.021
pigmentation GO:0043473 85 0.021
cilium organization GO:0044782 71 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
eye development GO:0001654 277 0.021
response to hexose GO:0009746 3 0.021
regulation of autophagy GO:0010506 3 0.021
single organism organelle organization GO:1902589 199 0.021
camera type eye development GO:0043010 222 0.021
phosphate containing compound metabolic process GO:0006796 108 0.020
wnt signaling pathway GO:0016055 80 0.020
cell migration involved in gastrulation GO:0042074 79 0.020
organic acid metabolic process GO:0006082 31 0.020
regulation of cell activation GO:0050865 1 0.020
digestive tract development GO:0048565 265 0.020
protein import into nucleus GO:0006606 3 0.020
neural tube formation GO:0001841 16 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
response to glucose GO:0009749 3 0.020
muscle structure development GO:0061061 196 0.020
vasculature development GO:0001944 278 0.019
regulation of reproductive process GO:2000241 4 0.019
blood vessel development GO:0001568 246 0.019
defense response to bacterium GO:0042742 22 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
organelle assembly GO:0070925 110 0.019
phosphorus metabolic process GO:0006793 109 0.019
purine nucleotide metabolic process GO:0006163 27 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
cell part morphogenesis GO:0032990 246 0.019
angiogenesis GO:0001525 158 0.019
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.019
stem cell maintenance GO:0019827 4 0.019
protein import GO:0017038 3 0.019
cytokinesis GO:0000910 3 0.018
neural tube development GO:0021915 62 0.018
cilium assembly GO:0042384 58 0.018
single organism intracellular transport GO:1902582 25 0.018
Human
regulation of muscle contraction GO:0006937 3 0.018
macromolecule localization GO:0033036 54 0.018
Human
response to topologically incorrect protein GO:0035966 2 0.018
Human
protein modification process GO:0036211 100 0.018
regulation of molecular function GO:0065009 70 0.018
developmental growth GO:0048589 166 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
golgi organization GO:0007030 1 0.018
cell migration GO:0016477 237 0.018
regulation of response to stimulus GO:0048583 269 0.018
regulation of protein targeting GO:1903533 2 0.018
exocytosis GO:0006887 1 0.018
cellular component biogenesis GO:0044085 178 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
organophosphate metabolic process GO:0019637 37 0.018
cellular component movement GO:0006928 335 0.018
blood vessel morphogenesis GO:0048514 216 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
regulation of gene expression GO:0010468 265 0.017
gene expression GO:0010467 252 0.017
translational initiation GO:0006413 3 0.017
negative regulation of protein transport GO:0051224 3 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
cell motility GO:0048870 244 0.017
cellular ketone metabolic process GO:0042180 11 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
homeostatic process GO:0042592 142 0.017
regulation of translational initiation GO:0006446 1 0.017
regulation of cell death GO:0010941 103 0.017
cellular pigmentation GO:0033059 30 0.017
cellular response to stress GO:0033554 62 0.016
Human
muscle cell development GO:0055001 115 0.016
peptidyl serine modification GO:0018209 2 0.016
interspecies interaction between organisms GO:0044419 4 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
negative regulation of cell communication GO:0010648 96 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
single organism nuclear import GO:1902593 3 0.016
purine ribonucleotide metabolic process GO:0009150 27 0.016
regulation of wnt signaling pathway GO:0030111 53 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
response to corticosteroid GO:0031960 1 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
neurotransmitter transport GO:0006836 2 0.015
epithelial cell differentiation GO:0030855 116 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
nuclear import GO:0051170 3 0.015
developmental programmed cell death GO:0010623 4 0.015
rna metabolic process GO:0016070 219 0.015
striated muscle cell development GO:0055002 108 0.015
ribonucleotide metabolic process GO:0009259 27 0.015
sexual reproduction GO:0019953 36 0.015
regulation of cell development GO:0060284 100 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
regulation of growth GO:0040008 42 0.015
localization of cell GO:0051674 244 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
negative regulation of reproductive process GO:2000242 3 0.015
cellular component disassembly GO:0022411 1 0.015
membrane fusion GO:0061025 2 0.015
sensory organ morphogenesis GO:0090596 200 0.015
glial cell migration GO:0008347 3 0.015
regulation of catalytic activity GO:0050790 55 0.015
regulation of blood pressure GO:0008217 1 0.014
embryonic limb morphogenesis GO:0030326 2 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
response to uv GO:0009411 3 0.014
cellular response to oxygen levels GO:0071453 1 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
regulation of protein binding GO:0043393 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
mitochondrion organization GO:0007005 4 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
mesenchyme development GO:0060485 127 0.014
single organism membrane organization GO:0044802 20 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
germ line stem cell maintenance GO:0030718 2 0.014
osteoclast differentiation GO:0030316 1 0.014
neuroblast proliferation GO:0007405 2 0.014
regulation of nervous system development GO:0051960 90 0.014
response to nutrient GO:0007584 3 0.013
positive regulation of signaling GO:0023056 56 0.013
locomotion GO:0040011 313 0.013
spermatid differentiation GO:0048515 2 0.013
recombinational repair GO:0000725 1 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
organic substance catabolic process GO:1901575 28 0.013
Human
response to external stimulus GO:0009605 264 0.013
defense response to other organism GO:0098542 33 0.013
compound eye development GO:0048749 2 0.013
axon cargo transport GO:0008088 2 0.013
ear development GO:0043583 127 0.013
multicellular organismal response to stress GO:0033555 2 0.013
stem cell division GO:0017145 1 0.013
morphogenesis of embryonic epithelium GO:0016331 30 0.013
regulation of organ growth GO:0046620 3 0.013
nucleoside phosphate metabolic process GO:0006753 28 0.013
system process GO:0003008 185 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
localization within membrane GO:0051668 1 0.013
actin filament based movement GO:0030048 1 0.013
regulation of programmed cell death GO:0043067 101 0.013
embryonic axis specification GO:0000578 12 0.013
striated muscle cell differentiation GO:0051146 129 0.012
muscle fiber development GO:0048747 52 0.012
muscle cell differentiation GO:0042692 139 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
pancreas development GO:0031016 84 0.012
catabolic process GO:0009056 32 0.012
Human
cell surface receptor signaling pathway GO:0007166 325 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
photoreceptor cell development GO:0042461 40 0.012
organelle localization GO:0051640 49 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
neurotransmitter secretion GO:0007269 2 0.012
positive regulation of translation GO:0045727 1 0.012
macromolecule modification GO:0043412 111 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
negative regulation of signal transduction GO:0009968 94 0.012
nuclear transport GO:0051169 4 0.012
immune system development GO:0002520 191 0.011
regulation of cellular component movement GO:0051270 55 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
protein k48 linked ubiquitination GO:0070936 1 0.011
meiotic nuclear division GO:0007126 4 0.011
nucleic acid metabolic process GO:0090304 244 0.011
response to hypoxia GO:0001666 25 0.011
oxoacid metabolic process GO:0043436 31 0.011
stem cell proliferation GO:0072089 4 0.011
purine ribonucleoside biosynthetic process GO:0046129 2 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
post anal tail morphogenesis GO:0036342 19 0.011
cellular amide metabolic process GO:0043603 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
protein polyubiquitination GO:0000209 4 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
muscle cell migration GO:0014812 4 0.011
cellular protein modification process GO:0006464 100 0.011
response to glucocorticoid GO:0051384 1 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
negative regulation of kinase activity GO:0033673 4 0.011
kidney development GO:0001822 92 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
lateral inhibition GO:0046331 1 0.011
purine ribonucleoside metabolic process GO:0046128 10 0.011
glucose homeostasis GO:0042593 1 0.011
endosomal transport GO:0016197 2 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
heart development GO:0007507 313 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
protein n linked glycosylation GO:0006487 1 0.011
germ line stem cell division GO:0042078 1 0.011
somatic stem cell maintenance GO:0035019 1 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
skeletal system morphogenesis GO:0048705 102 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
skeletal muscle tissue development GO:0007519 67 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
positive regulation of cell activation GO:0050867 1 0.010
positive regulation of protein metabolic process GO:0051247 23 0.010
dopaminergic neuron differentiation GO:0071542 14 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
organ regeneration GO:0031100 1 0.010
convergent extension GO:0060026 118 0.010
er nucleus signaling pathway GO:0006984 2 0.010
Human
ribonucleotide biosynthetic process GO:0009260 20 0.010
ribonucleoside metabolic process GO:0009119 11 0.010
regulation of developmental growth GO:0048638 38 0.010
renal system development GO:0072001 94 0.010
positive regulation of developmental process GO:0051094 50 0.010
entrainment of circadian clock GO:0009649 2 0.010

derl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071
nervous system disease DOID:863 0 0.025
muscular disease DOID:0080000 0 0.023
musculoskeletal system disease DOID:17 0 0.023
sensory system disease DOID:0050155 0 0.015
muscle tissue disease DOID:66 0 0.011