Danio rerio

0 known processes

derl2

Der1-like domain family, member 2

(Aliases: zgc:110436)

derl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.174
locomotion GO:0040011 313 0.076
aging GO:0007568 2 0.075
cognition GO:0050890 1 0.073
nucleobase containing compound metabolic process GO:0006139 274 0.054
heterocycle metabolic process GO:0046483 290 0.049
modification dependent protein catabolic process GO:0019941 3 0.047
meiotic nuclear division GO:0007126 4 0.046
multicellular organism growth GO:0035264 4 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.046
establishment of localization GO:0051234 244 0.046
positive regulation of transport GO:0051050 2 0.045
cell projection organization GO:0030030 284 0.043
cellular macromolecule metabolic process GO:0044260 391 0.042
regulation of biosynthetic process GO:0009889 250 0.041
organic cyclic compound metabolic process GO:1901360 301 0.039
negative regulation of protein kinase activity GO:0006469 4 0.039
regulation of nucleoside metabolic process GO:0009118 2 0.039
positive regulation of cellular catabolic process GO:0031331 3 0.039
organic substance biosynthetic process GO:1901576 289 0.039
maintenance of location GO:0051235 4 0.039
protein localization to nucleus GO:0034504 3 0.038
cellular component movement GO:0006928 335 0.038
protein metabolic process GO:0019538 183 0.037
positive regulation of biological process GO:0048518 253 0.037
macromolecule biosynthetic process GO:0009059 227 0.036
negative regulation of biological process GO:0048519 304 0.036
embryo development ending in birth or egg hatching GO:0009792 271 0.035
sensory organ development GO:0007423 393 0.035
modification dependent macromolecule catabolic process GO:0043632 3 0.033
generation of neurons GO:0048699 385 0.033
i kappab kinase nf kappab signaling GO:0007249 4 0.033
cellular protein modification process GO:0006464 100 0.033
multi organism cellular process GO:0044764 2 0.033
regulation of purine nucleotide catabolic process GO:0033121 2 0.033
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
cellular component morphogenesis GO:0032989 336 0.031
guanosine containing compound catabolic process GO:1901069 2 0.031
response to chemical GO:0042221 320 0.030
Worm
positive regulation of catabolic process GO:0009896 4 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.030
stem cell proliferation GO:0072089 4 0.029
amine metabolic process GO:0009308 2 0.028
stem cell maintenance GO:0019827 4 0.028
neuroblast proliferation GO:0007405 2 0.028
cellular amine metabolic process GO:0044106 2 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.028
regulation of primary metabolic process GO:0080090 311 0.028
cellular protein metabolic process GO:0044267 129 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.027
transport GO:0006810 220 0.026
cell morphogenesis GO:0000902 289 0.026
death GO:0016265 121 0.026
cellular ketone metabolic process GO:0042180 11 0.026
protein import into nucleus GO:0006606 3 0.026
response to stress GO:0006950 263 0.025
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
neurological system process GO:0050877 62 0.025
rna metabolic process GO:0016070 219 0.025
small molecule metabolic process GO:0044281 77 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
cellular response to nutrient levels GO:0031669 2 0.025
gtp metabolic process GO:0046039 4 0.025
carbohydrate derivative metabolic process GO:1901135 61 0.025
protein targeting to nucleus GO:0044744 3 0.024
positive regulation of nucleoside metabolic process GO:0045979 1 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
organelle organization GO:0006996 227 0.024
gtp catabolic process GO:0006184 2 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
regulation of protein localization to nucleus GO:1900180 2 0.024
nuclear transport GO:0051169 4 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
signal transduction GO:0007165 455 0.023
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
regulation of protein transport GO:0051223 3 0.023
cellular component assembly GO:0022607 170 0.023
regulation of programmed cell death GO:0043067 101 0.023
chordate embryonic development GO:0043009 271 0.023
lipid storage GO:0019915 1 0.023
positive regulation of cellular process GO:0048522 201 0.022
response to organic substance GO:0010033 153 0.022
Worm
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.022
positive regulation of nucleotide catabolic process GO:0030813 1 0.022
cell projection morphogenesis GO:0048858 244 0.022
nuclear import GO:0051170 3 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
regulation of cytokine production GO:0001817 3 0.021
cellular response to external stimulus GO:0071496 2 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
neuron development GO:0048666 262 0.021
negative regulation of cellular process GO:0048523 283 0.021
regulation of cell death GO:0010941 103 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
negative regulation of protein localization to nucleus GO:1900181 2 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
cytoskeleton dependent cytokinesis GO:0061640 3 0.020
peptide metabolic process GO:0006518 1 0.020
cellular response to starvation GO:0009267 1 0.019
cell death GO:0008219 121 0.019
positive regulation of secretion GO:0051047 1 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
blood vessel development GO:0001568 246 0.019
regulation of binding GO:0051098 3 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
tube morphogenesis GO:0035239 349 0.019
alcohol biosynthetic process GO:0046165 2 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
viral process GO:0016032 1 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
regionalization GO:0003002 274 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
regulation of signal transduction GO:0009966 225 0.019
multi organism process GO:0051704 134 0.019
phagocytosis GO:0006909 3 0.019
biosynthetic process GO:0009058 294 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
meiotic chromosome segregation GO:0045132 3 0.018
protein modification process GO:0036211 100 0.018
chemosensory behavior GO:0007635 1 0.018
peptide transport GO:0015833 1 0.018
regulation of cellular component organization GO:0051128 86 0.018
response to nutrient GO:0007584 3 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
cell migration GO:0016477 237 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
regulation of metabolic process GO:0019222 359 0.018
single organism metabolic process GO:0044710 217 0.018
regulation of signaling GO:0023051 235 0.018
regulation of developmental process GO:0050793 247 0.018
heart development GO:0007507 313 0.018
regulation of metal ion transport GO:0010959 4 0.018
mitotic cytokinesis GO:0000281 3 0.018
nucleic acid metabolic process GO:0090304 244 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
organic acid metabolic process GO:0006082 31 0.017
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.017
cytokinesis GO:0000910 3 0.017
locomotor rhythm GO:0045475 3 0.017
neuron differentiation GO:0030182 353 0.017
positive regulation of cell cycle GO:0045787 3 0.017
regulation of protein targeting GO:1903533 2 0.017
oxoacid metabolic process GO:0043436 31 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
localization of cell GO:0051674 244 0.017
negative regulation of protein import into nucleus GO:0042308 2 0.017
regulation of apoptotic process GO:0042981 98 0.016
gland development GO:0048732 143 0.016
protein import GO:0017038 3 0.016
regulation of gtpase activity GO:0043087 2 0.016
cellular protein catabolic process GO:0044257 4 0.016
primary neural tube formation GO:0014020 1 0.016
interspecies interaction between organisms GO:0044419 4 0.016
regulation of response to stimulus GO:0048583 269 0.016
axon development GO:0061564 166 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.016
phosphorus metabolic process GO:0006793 109 0.016
negative regulation of kinase activity GO:0033673 4 0.016
sensory organ morphogenesis GO:0090596 200 0.016
meiotic cell cycle process GO:1903046 3 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
cellular component biogenesis GO:0044085 178 0.016
eye development GO:0001654 277 0.016
liver development GO:0001889 96 0.016
regulation of filopodium assembly GO:0051489 2 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
embryonic organ development GO:0048568 381 0.015
negative regulation of protein transport GO:0051224 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
translational initiation GO:0006413 3 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
negative regulation of intracellular protein transport GO:0090317 3 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
macromolecule modification GO:0043412 111 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
regulation of reproductive process GO:2000241 4 0.015
regulation of protein metabolic process GO:0051246 56 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
endosome organization GO:0007032 2 0.015
regulation of cell communication GO:0010646 232 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
protein secretion GO:0009306 1 0.014
regulation of transporter activity GO:0032409 2 0.014
vasculature development GO:0001944 278 0.014
regulation of gene expression GO:0010468 265 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
atp catabolic process GO:0006200 4 0.014
rna 3 end processing GO:0031123 2 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
hepaticobiliary system development GO:0061008 98 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of cell activation GO:0050865 1 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
g2 m transition of mitotic cell cycle GO:0000086 4 0.014
germ line stem cell maintenance GO:0030718 2 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
negative regulation of cell death GO:0060548 60 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of protein catabolic process GO:0042176 1 0.013
positive regulation of immune effector process GO:0002699 3 0.013
cell substrate junction assembly GO:0007044 2 0.013
nuclear export GO:0051168 1 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
somite development GO:0061053 96 0.013
eye morphogenesis GO:0048592 144 0.013
stem cell division GO:0017145 1 0.013
programmed cell death GO:0012501 119 0.013
cellular biosynthetic process GO:0044249 286 0.013
regulation of organ growth GO:0046620 3 0.013
cellular nitrogen compound catabolic process GO:0044270 15 0.013
system process GO:0003008 185 0.013
organelle assembly GO:0070925 110 0.013
rna biosynthetic process GO:0032774 181 0.013
immune system process GO:0002376 241 0.013
positive regulation of cytokine production GO:0001819 2 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of rna metabolic process GO:0051252 224 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
protein localization to plasma membrane GO:0072659 1 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
compound eye development GO:0048749 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
negative regulation of neural precursor cell proliferation GO:2000178 1 0.013
cilium morphogenesis GO:0060271 85 0.013
positive regulation of signal transduction GO:0009967 56 0.012
post embryonic morphogenesis GO:0009886 4 0.012
regulation of dendrite development GO:0050773 3 0.012
neuron projection morphogenesis GO:0048812 161 0.012
cellular macromolecule catabolic process GO:0044265 12 0.012
adult behavior GO:0030534 2 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
mitochondrion organization GO:0007005 4 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
cell cycle arrest GO:0007050 1 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
transcription dna templated GO:0006351 181 0.012
anterior posterior pattern specification GO:0009952 152 0.012
inner ear development GO:0048839 126 0.012
synaptic vesicle transport GO:0048489 1 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
gene expression GO:0010467 252 0.012
somitogenesis GO:0001756 87 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
neurotransmitter transport GO:0006836 2 0.012
growth GO:0040007 174 0.012
regulation of catalytic activity GO:0050790 55 0.012
macroautophagy GO:0016236 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
regulation of membrane potential GO:0042391 23 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
Worm
cellular response to oxygen levels GO:0071453 1 0.012
regulation of molecular function GO:0065009 70 0.012
melanin metabolic process GO:0006582 2 0.012
osteoclast differentiation GO:0030316 1 0.012
single organism localization GO:1902578 225 0.012
microtubule organizing center organization GO:0031023 1 0.012
regulation of protein ubiquitination GO:0031396 3 0.011
nucleobase containing compound transport GO:0015931 2 0.011
synaptic vesicle localization GO:0097479 1 0.011
taxis GO:0042330 109 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
regulation of cell cycle GO:0051726 52 0.011
response to glucocorticoid GO:0051384 1 0.011
response to hexose GO:0009746 3 0.011
positive regulation of cell activation GO:0050867 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
secondary metabolic process GO:0019748 3 0.011
neurotransmitter secretion GO:0007269 2 0.011
cytoplasm organization GO:0007028 4 0.011
ear development GO:0043583 127 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.011
cellular amide metabolic process GO:0043603 4 0.011
hormone transport GO:0009914 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
response to unfolded protein GO:0006986 2 0.011
Worm
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
cellular response to hypoxia GO:0071456 1 0.011
sleep GO:0030431 1 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
negative regulation of catabolic process GO:0009895 3 0.011
negative regulation of metabolic process GO:0009892 86 0.011
peptidyl serine modification GO:0018209 2 0.011
developmental growth GO:0048589 166 0.010
cellular catabolic process GO:0044248 27 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
rna localization GO:0006403 4 0.010
cell projection assembly GO:0030031 64 0.010
cell part morphogenesis GO:0032990 246 0.010
axon guidance GO:0007411 86 0.010
protein complex localization GO:0031503 1 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
regulation of protein complex assembly GO:0043254 3 0.010
single organism nuclear import GO:1902593 3 0.010
organelle fusion GO:0048284 3 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
lateral inhibition GO:0046331 1 0.010
autophagy GO:0006914 4 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010

derl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.020
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
connective tissue disease DOID:65 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010