Danio rerio

0 known processes

ndel1b

nudE nuclear distribution gene E homolog like 1 (A. nidulans) B

(Aliases: wu:fi23e06,wu:fi23c04)

ndel1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.310
cell surface receptor signaling pathway GO:0007166 325 0.237
regulation of metabolic process GO:0019222 359 0.193
Mouse
regulation of primary metabolic process GO:0080090 311 0.121
Mouse
centrosome organization GO:0051297 1 0.105
Mouse
modification dependent protein catabolic process GO:0019941 3 0.101
maintenance of location GO:0051235 4 0.100
regulation of response to stimulus GO:0048583 269 0.093
Mouse
regulation of signal transduction GO:0009966 225 0.081
Mouse
intracellular signal transduction GO:0035556 85 0.076
cellular protein catabolic process GO:0044257 4 0.076
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.074
proteasomal protein catabolic process GO:0010498 2 0.072
cellular nitrogen compound biosynthetic process GO:0044271 218 0.072
meiotic nuclear division GO:0007126 4 0.072
lipid storage GO:0019915 1 0.066
regulation of cell communication GO:0010646 232 0.064
Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.064
regulation of gene expression GO:0010468 265 0.064
macromolecule biosynthetic process GO:0009059 227 0.063
centrosome cycle GO:0007098 1 0.063
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.061
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.059
regionalization GO:0003002 274 0.057
muscle tissue development GO:0060537 110 0.057
microtubule organizing center organization GO:0031023 1 0.057
Mouse
extrinsic apoptotic signaling pathway GO:0097191 3 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.055
Mouse
heterocycle metabolic process GO:0046483 290 0.055
Mouse
nitrogen compound metabolic process GO:0006807 319 0.054
Mouse
wnt signaling pathway GO:0016055 80 0.052
neuron development GO:0048666 262 0.051
Mouse
positive regulation of cellular process GO:0048522 201 0.051
Mouse
response to stress GO:0006950 263 0.049
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
Mouse
regulation of transcription dna templated GO:0006355 213 0.049
regulation of rna biosynthetic process GO:2001141 213 0.048
apoptotic process GO:0006915 116 0.046
negative regulation of response to stimulus GO:0048585 104 0.046
anion transport GO:0006820 38 0.046
negative regulation of cell communication GO:0010648 96 0.044
meiotic cell cycle process GO:1903046 3 0.044
negative regulation of signal transduction GO:0009968 94 0.041
sulfur compound transport GO:0072348 3 0.040
single organism localization GO:1902578 225 0.040
Mouse
establishment of localization GO:0051234 244 0.040
Mouse
sprouting angiogenesis GO:0002040 53 0.040
negative regulation of biological process GO:0048519 304 0.039
regulation of protein catabolic process GO:0042176 1 0.039
cellular biosynthetic process GO:0044249 286 0.038
aromatic compound biosynthetic process GO:0019438 217 0.037
transmembrane transport GO:0055085 120 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.036
organic cyclic compound metabolic process GO:1901360 301 0.036
Mouse
negative regulation of cellular process GO:0048523 283 0.036
regulation of rna metabolic process GO:0051252 224 0.036
single organism organelle organization GO:1902589 199 0.036
Mouse
modification dependent macromolecule catabolic process GO:0043632 3 0.035
g protein coupled receptor signaling pathway GO:0007186 74 0.035
cellular response to external stimulus GO:0071496 2 0.035
system process GO:0003008 185 0.035
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.035
positive regulation of catabolic process GO:0009896 4 0.034
Mouse
regulation of programmed cell death GO:0043067 101 0.033
adult behavior GO:0030534 2 0.033
regulation of biosynthetic process GO:0009889 250 0.033
single organism metabolic process GO:0044710 217 0.033
Mouse
muscle cell development GO:0055001 115 0.032
regulation of signaling GO:0023051 235 0.032
Mouse
cell projection organization GO:0030030 284 0.032
Mouse
autophagy GO:0006914 4 0.032
protein modification process GO:0036211 100 0.031
striated muscle cell differentiation GO:0051146 129 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.031
positive regulation of transport GO:0051050 2 0.030
programmed cell death GO:0012501 119 0.030
enzyme linked receptor protein signaling pathway GO:0007167 106 0.030
cellular macromolecule metabolic process GO:0044260 391 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
response to radiation GO:0009314 51 0.029
response to glucocorticoid GO:0051384 1 0.029
central nervous system development GO:0007417 387 0.028
Mouse
protein localization to nucleus GO:0034504 3 0.028
cellular response to nutrient levels GO:0031669 2 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.028
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.027
embryonic organ development GO:0048568 381 0.027
amine metabolic process GO:0009308 2 0.027
skeletal system development GO:0001501 181 0.027
cellular response to starvation GO:0009267 1 0.027
protein polyubiquitination GO:0000209 4 0.027
ion transport GO:0006811 114 0.027
positive regulation of catalytic activity GO:0043085 25 0.026
Mouse
protein metabolic process GO:0019538 183 0.026
peptidyl serine phosphorylation GO:0018105 1 0.026
head development GO:0060322 303 0.026
Mouse
morphogenesis of an epithelium GO:0002009 333 0.026
nucleic acid templated transcription GO:0097659 181 0.026
aging GO:0007568 2 0.026
cellular protein metabolic process GO:0044267 129 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
inositol lipid mediated signaling GO:0048017 2 0.025
organic anion transport GO:0015711 15 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
negative regulation of cell death GO:0060548 60 0.024
cell death GO:0008219 121 0.024
dna templated transcription initiation GO:0006352 1 0.024
heart development GO:0007507 313 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
dicarboxylic acid transport GO:0006835 1 0.024
negative regulation of signaling GO:0023057 96 0.024
negative regulation of programmed cell death GO:0043069 58 0.024
transcription dna templated GO:0006351 181 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
amino acid transport GO:0006865 2 0.023
regulation of biological quality GO:0065008 263 0.023
endosomal transport GO:0016197 2 0.023
macromolecule modification GO:0043412 111 0.023
response to inorganic substance GO:0010035 38 0.023
rna biosynthetic process GO:0032774 181 0.022
cellular response to decreased oxygen levels GO:0036294 1 0.022
regulation of dendrite development GO:0050773 3 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.022
sphingolipid biosynthetic process GO:0030148 2 0.022
protein polymerization GO:0051258 4 0.022
response to alkaloid GO:0043279 2 0.022
heterocycle biosynthetic process GO:0018130 215 0.021
establishment of synaptic vesicle localization GO:0097480 1 0.021
regulation of response to oxidative stress GO:1902882 2 0.021
actin polymerization or depolymerization GO:0008154 2 0.021
protein complex subunit organization GO:0071822 46 0.021
membrane lipid biosynthetic process GO:0046467 2 0.021
regulation of multicellular organismal development GO:2000026 223 0.020
Mouse
regulation of protein transport GO:0051223 3 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
response to organic substance GO:0010033 153 0.020
muscle cell differentiation GO:0042692 139 0.020
ion transmembrane transport GO:0034220 91 0.020
regulation of apoptotic process GO:0042981 98 0.020
regulation of blood vessel size GO:0050880 2 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.019
response to nutrient GO:0007584 3 0.019
cognition GO:0050890 1 0.019
cellular modified amino acid metabolic process GO:0006575 3 0.019
cellular component biogenesis GO:0044085 178 0.019
cardiac muscle cell development GO:0055013 20 0.019
response to chemical GO:0042221 320 0.019
organic substance biosynthetic process GO:1901576 289 0.019
cellular response to organic substance GO:0071310 105 0.019
actin filament polymerization GO:0030041 2 0.019
regulation of nervous system development GO:0051960 90 0.019
Mouse
biosynthetic process GO:0009058 294 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
apoptotic signaling pathway GO:0097190 23 0.018
cellular response to stress GO:0033554 62 0.018
cellular component disassembly GO:0022411 1 0.018
hydrogen peroxide metabolic process GO:0042743 2 0.018
carbohydrate homeostasis GO:0033500 1 0.018
cell part morphogenesis GO:0032990 246 0.018
Mouse
regulation of ph GO:0006885 3 0.018
regulation of protein complex assembly GO:0043254 3 0.017
transport GO:0006810 220 0.017
Mouse
regulation of wnt signaling pathway GO:0030111 53 0.017
response to hexose GO:0009746 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
response to corticosteroid GO:0031960 1 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
regulation of cell death GO:0010941 103 0.017
peptide transport GO:0015833 1 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
vasculature development GO:0001944 278 0.017
regulation of tube size GO:0035150 2 0.017
organelle assembly GO:0070925 110 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
response to abiotic stimulus GO:0009628 122 0.017
regulation of gtpase activity GO:0043087 2 0.017
Mouse
positive regulation of biological process GO:0048518 253 0.017
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.016
Mouse
cellular amino acid metabolic process GO:0006520 7 0.016
negative regulation of kinase activity GO:0033673 4 0.016
catecholamine metabolic process GO:0006584 2 0.016
cellular response to oxygen levels GO:0071453 1 0.016
cellular protein modification process GO:0006464 100 0.016
cytoplasm organization GO:0007028 4 0.016
regulation of system process GO:0044057 40 0.016
gene expression GO:0010467 252 0.016
single organism transport GO:0044765 206 0.015
Mouse
phosphatidylinositol mediated signaling GO:0048015 2 0.015
s adenosylmethionine metabolic process GO:0046500 1 0.015
positive regulation of cell cycle GO:0045787 3 0.015
neuron differentiation GO:0030182 353 0.015
Mouse
regulation of catalytic activity GO:0050790 55 0.015
Mouse
ceramide biosynthetic process GO:0046513 1 0.015
cellular transition metal ion homeostasis GO:0046916 3 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
Mouse
fat soluble vitamin biosynthetic process GO:0042362 2 0.015
glucose import GO:0046323 2 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
Mouse
growth GO:0040007 174 0.015
Mouse
response to glucose GO:0009749 3 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
striated muscle cell development GO:0055002 108 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
cellular response to hypoxia GO:0071456 1 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
b cell activation GO:0042113 2 0.014
protein dephosphorylation GO:0006470 3 0.014
death GO:0016265 121 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
response to endogenous stimulus GO:0009719 83 0.014
striated muscle tissue development GO:0014706 110 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
detection of abiotic stimulus GO:0009582 24 0.014
actin filament based process GO:0030029 64 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
Mouse
rna metabolic process GO:0016070 219 0.014
apoptotic process involved in development GO:1902742 2 0.014
negative regulation of intracellular signal transduction GO:1902532 22 0.014
er to golgi vesicle mediated transport GO:0006888 1 0.014
chordate embryonic development GO:0043009 271 0.013
Mouse
nucleocytoplasmic transport GO:0006913 4 0.013
homeostatic process GO:0042592 142 0.013
stem cell proliferation GO:0072089 4 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
Mouse
response to hydrogen peroxide GO:0042542 3 0.013
response to carbohydrate GO:0009743 3 0.013
negative regulation of metabolic process GO:0009892 86 0.013
regulation of membrane potential GO:0042391 23 0.013
regulation of protein metabolic process GO:0051246 56 0.013
regulation of reproductive process GO:2000241 4 0.013
mitochondrion organization GO:0007005 4 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.012
meiosis i GO:0007127 1 0.012
cellular amine metabolic process GO:0044106 2 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.012
localization of cell GO:0051674 244 0.012
Mouse
determination of left right symmetry GO:0007368 179 0.012
regulation of protein binding GO:0043393 3 0.012
regulation of response to stress GO:0080134 36 0.012
protein complex localization GO:0031503 1 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
neuron projection morphogenesis GO:0048812 161 0.012
Mouse
cellular component maintenance GO:0043954 3 0.012
protein complex biogenesis GO:0070271 30 0.012
circulatory system process GO:0003013 87 0.012
regulation of protein polymerization GO:0032271 2 0.012
mitotic cell cycle GO:0000278 64 0.012
Mouse
regulation of transporter activity GO:0032409 2 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
Mouse
glucose homeostasis GO:0042593 1 0.012
cell substrate adhesion GO:0031589 4 0.012
embryonic skeletal system development GO:0048706 97 0.012
brain development GO:0007420 293 0.012
Mouse
appendage development GO:0048736 80 0.011
protein import GO:0017038 3 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
membrane lipid metabolic process GO:0006643 10 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
proteolysis GO:0006508 38 0.011
protein k48 linked ubiquitination GO:0070936 1 0.011
signal transduction by p53 class mediator GO:0072331 13 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.011
regulation of cell cycle GO:0051726 52 0.011
positive regulation of ras gtpase activity GO:0032320 1 0.011
Mouse
regulation of binding GO:0051098 3 0.011
response to drug GO:0042493 3 0.011
peptidyl serine modification GO:0018209 2 0.011
organic acid metabolic process GO:0006082 31 0.011
regulation of organelle assembly GO:1902115 4 0.011
organelle organization GO:0006996 227 0.011
Mouse
blood vessel development GO:0001568 246 0.011
nuclear transport GO:0051169 4 0.011
alcohol biosynthetic process GO:0046165 2 0.011
positive regulation of striated muscle cell differentiation GO:0051155 1 0.011
regulation of glucose transport GO:0010827 1 0.011
sensory organ development GO:0007423 393 0.011
establishment of localization in cell GO:0051649 77 0.011
Mouse
regulation of synapse organization GO:0050807 3 0.011
modification by symbiont of host morphology or physiology GO:0044003 4 0.011
protein phosphorylation GO:0006468 47 0.011
nucleic acid metabolic process GO:0090304 244 0.011
macromolecule localization GO:0033036 54 0.011
single organism membrane fusion GO:0044801 2 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
skeletal system morphogenesis GO:0048705 102 0.011
regulation of autophagy GO:0010506 3 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.011
regulation of cell projection assembly GO:0060491 4 0.010
locomotor rhythm GO:0045475 3 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
Mouse
b cell mediated immunity GO:0019724 3 0.010
cellular component assembly GO:0022607 170 0.010
iron ion homeostasis GO:0055072 4 0.010
organelle fusion GO:0048284 3 0.010
protein targeting to membrane GO:0006612 1 0.010
single organism nuclear import GO:1902593 3 0.010
regulation of cytokine production GO:0001817 3 0.010
response to uv GO:0009411 3 0.010
cell migration GO:0016477 237 0.010
Mouse
multicellular organismal metabolic process GO:0044236 2 0.010
regulation of dna templated transcription in response to stress GO:0043620 0 0.010
cardiac muscle tissue development GO:0048738 48 0.010
eye morphogenesis GO:0048592 144 0.010
protein complex disassembly GO:0043241 1 0.010
positive regulation of cell substrate adhesion GO:0010811 1 0.010
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.010
detection of external stimulus GO:0009581 24 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
Mouse
hormone secretion GO:0046879 2 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
developmental programmed cell death GO:0010623 4 0.010
lateral inhibition GO:0046331 1 0.010
regulation of organ growth GO:0046620 3 0.010
macromolecular complex disassembly GO:0032984 1 0.010
generation of neurons GO:0048699 385 0.010
Mouse
digestive system development GO:0055123 289 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.010

ndel1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
immune system disease DOID:2914 0 0.015
hematopoietic system disease DOID:74 0 0.015
bone disease DOID:0080001 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
disease of cellular proliferation DOID:14566 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
nervous system disease DOID:863 0 0.011
eye disease DOID:5614 0 0.011
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011