Danio rerio

0 known processes

pppde2a

PPPDE peptidase domain containing 2a

(Aliases: MGC73066,fam152ba,zgc:73066)

pppde2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.168
embryo development ending in birth or egg hatching GO:0009792 271 0.110
regulation of response to stimulus GO:0048583 269 0.108
larval development GO:0002164 2 0.100
chordate embryonic development GO:0043009 271 0.087
cellular component movement GO:0006928 335 0.082
cell surface receptor signaling pathway GO:0007166 325 0.078
synaptic growth at neuromuscular junction GO:0051124 2 0.070
negative regulation of cellular process GO:0048523 283 0.070
negative regulation of biological process GO:0048519 304 0.069
signal transduction GO:0007165 455 0.065
regulation of multicellular organismal development GO:2000026 223 0.062
regulation of cell projection assembly GO:0060491 4 0.060
regulation of reproductive process GO:2000241 4 0.060
eye development GO:0001654 277 0.059
blood vessel development GO:0001568 246 0.056
regulation of protein complex assembly GO:0043254 3 0.053
regulation of metabolic process GO:0019222 359 0.052
regulation of multicellular organismal process GO:0051239 277 0.050
regulation of cell communication GO:0010646 232 0.050
exocytosis GO:0006887 1 0.048
organonitrogen compound metabolic process GO:1901564 74 0.046
growth GO:0040007 174 0.045
regulation of multicellular organism growth GO:0040014 4 0.044
meiotic nuclear division GO:0007126 4 0.044
response to external stimulus GO:0009605 264 0.044
regulation of signal transduction GO:0009966 225 0.044
heart development GO:0007507 313 0.042
regulation of signaling GO:0023051 235 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.040
cell migration GO:0016477 237 0.039
single organism localization GO:1902578 225 0.038
regulation of biological quality GO:0065008 263 0.038
guanosine containing compound catabolic process GO:1901069 2 0.037
regulation of developmental process GO:0050793 247 0.037
regulation of filopodium assembly GO:0051489 2 0.037
multicellular organism growth GO:0035264 4 0.036
neurotransmitter secretion GO:0007269 2 0.036
peptidyl serine phosphorylation GO:0018105 1 0.036
sensory system development GO:0048880 76 0.036
regulation of protein transport GO:0051223 3 0.036
morphogenesis of an epithelium GO:0002009 333 0.036
fertilization GO:0009566 3 0.034
purine nucleoside monophosphate catabolic process GO:0009128 4 0.034
establishment of localization GO:0051234 244 0.033
camera type eye development GO:0043010 222 0.033
negative regulation of protein phosphorylation GO:0001933 4 0.032
synaptic transmission GO:0007268 35 0.032
neurotransmitter transport GO:0006836 2 0.031
gtp metabolic process GO:0046039 4 0.030
developmental growth GO:0048589 166 0.030
ameboidal type cell migration GO:0001667 143 0.030
response to chemical GO:0042221 320 0.030
cell motility GO:0048870 244 0.029
lateral line system development GO:0048925 76 0.029
rna localization GO:0006403 4 0.029
vasculature development GO:0001944 278 0.029
peptidyl threonine phosphorylation GO:0018107 1 0.028
mitochondrion organization GO:0007005 4 0.028
regulation of cellular component organization GO:0051128 86 0.027
response to external biotic stimulus GO:0043207 97 0.027
regulation of cell shape GO:0008360 1 0.027
single fertilization GO:0007338 3 0.026
generation of neurons GO:0048699 385 0.026
organelle fusion GO:0048284 3 0.026
response to carbohydrate GO:0009743 3 0.026
heterocycle metabolic process GO:0046483 290 0.026
angiogenesis GO:0001525 158 0.026
regulation of neurotransmitter transport GO:0051588 1 0.026
lateral line development GO:0048882 66 0.026
single organism membrane fusion GO:0044801 2 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
response to biotic stimulus GO:0009607 97 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
synaptic transmission cholinergic GO:0007271 4 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
hatching gland development GO:0048785 3 0.025
g protein coupled receptor signaling pathway GO:0007186 74 0.025
phosphate containing compound metabolic process GO:0006796 108 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
membrane fusion GO:0061025 2 0.024
positive regulation of secretion by cell GO:1903532 1 0.024
phosphorus metabolic process GO:0006793 109 0.024
response to other organism GO:0051707 97 0.024
guanosine containing compound metabolic process GO:1901068 4 0.023
regulation of cell differentiation GO:0045595 142 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
cellular response to external stimulus GO:0071496 2 0.023
digestive system development GO:0055123 289 0.023
localization of cell GO:0051674 244 0.023
cytoplasm organization GO:0007028 4 0.023
embryonic organ development GO:0048568 381 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
compound eye development GO:0048749 2 0.023
synaptic vesicle transport GO:0048489 1 0.023
meiotic cell cycle process GO:1903046 3 0.022
cell death GO:0008219 121 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
regulation of gtp catabolic process GO:0033124 2 0.022
single organism metabolic process GO:0044710 217 0.022
determination of bilateral symmetry GO:0009855 204 0.022
regulation of exocytosis GO:0017157 1 0.022
specification of symmetry GO:0009799 204 0.022
regulation of synapse assembly GO:0051963 3 0.022
regionalization GO:0003002 274 0.022
homeostatic process GO:0042592 142 0.021
nucleoside monophosphate catabolic process GO:0009125 4 0.021
tube morphogenesis GO:0035239 349 0.021
digestive tract development GO:0048565 265 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
amine metabolic process GO:0009308 2 0.021
protein dephosphorylation GO:0006470 3 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
calcium ion dependent exocytosis GO:0017156 1 0.020
regulation of muscle contraction GO:0006937 3 0.020
cellular component morphogenesis GO:0032989 336 0.020
protein targeting to membrane GO:0006612 1 0.020
aging GO:0007568 2 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
protein localization to plasma membrane GO:0072659 1 0.019
sleep GO:0030431 1 0.019
peptidyl serine modification GO:0018209 2 0.019
cell morphogenesis GO:0000902 289 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
cell part morphogenesis GO:0032990 246 0.019
nucleic acid transport GO:0050657 2 0.019
organic substance transport GO:0071702 58 0.019
cognition GO:0050890 1 0.019
response to monosaccharide GO:0034284 3 0.019
regulation of calcium ion transport GO:0051924 2 0.019
locomotion GO:0040011 313 0.019
single organism transport GO:0044765 206 0.019
multicellular organismal signaling GO:0035637 22 0.019
axon ensheathment in central nervous system GO:0032291 2 0.019
synaptic vesicle localization GO:0097479 1 0.019
eye morphogenesis GO:0048592 144 0.019
death GO:0016265 121 0.019
regulation of cyclase activity GO:0031279 12 0.018
regulation of neurotransmitter secretion GO:0046928 1 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
cell substrate adhesion GO:0031589 4 0.018
transport GO:0006810 220 0.018
regulation of neuronal synaptic plasticity GO:0048168 1 0.018
negative regulation of catabolic process GO:0009895 3 0.018
cell projection organization GO:0030030 284 0.018
single organism organelle organization GO:1902589 199 0.018
cellular component disassembly GO:0022411 1 0.018
regulation of metal ion transport GO:0010959 4 0.018
calcium mediated signaling GO:0019722 2 0.018
cellular localization GO:0051641 97 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
establishment of localization in cell GO:0051649 77 0.017
membrane invagination GO:0010324 1 0.017
regulation of protein polymerization GO:0032271 2 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
nucleobase containing compound transport GO:0015931 2 0.017
cell cell signaling GO:0007267 52 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
embryonic skeletal system development GO:0048706 97 0.016
nuclear transport GO:0051169 4 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
protein polymerization GO:0051258 4 0.016
positive regulation of transport GO:0051050 2 0.016
lamellipodium organization GO:0097581 1 0.016
regulation of circadian rhythm GO:0042752 4 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
negative regulation of cell communication GO:0010648 96 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
apoptotic process GO:0006915 116 0.016
regulation of nervous system development GO:0051960 90 0.016
embryonic cranial skeleton morphogenesis GO:0048701 90 0.016
regulation of synapse organization GO:0050807 3 0.016
response to food GO:0032094 1 0.016
phagocytosis engulfment GO:0006911 1 0.016
muscle structure development GO:0061061 196 0.016
positive regulation of cell activation GO:0050867 1 0.016
regulation of lyase activity GO:0051339 12 0.016
peptidyl threonine modification GO:0018210 1 0.016
cellular amine metabolic process GO:0044106 2 0.016
brain development GO:0007420 293 0.016
regulation of gtpase activity GO:0043087 2 0.015
regulation of oocyte development GO:0060281 3 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
inner ear development GO:0048839 126 0.015
small molecule metabolic process GO:0044281 77 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
hepaticobiliary system development GO:0061008 98 0.015
phagocytosis GO:0006909 3 0.015
negative regulation of secretion by cell GO:1903531 2 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.015
neuron development GO:0048666 262 0.015
neuron projection development GO:0031175 180 0.015
regulation of cell activation GO:0050865 1 0.015
female meiotic division GO:0007143 2 0.015
positive regulation of cell cycle GO:0045787 3 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
regulation of cytokine production GO:0001817 3 0.015
positive regulation of secretion GO:0051047 1 0.015
stem cell proliferation GO:0072089 4 0.015
establishment of organelle localization GO:0051656 45 0.015
system process GO:0003008 185 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
cytokinesis GO:0000910 3 0.015
muscle tissue development GO:0060537 110 0.015
cell projection assembly GO:0030031 64 0.015
regulation of calcium ion dependent exocytosis GO:0017158 1 0.015
positive regulation of catabolic process GO:0009896 4 0.014
negative regulation of kinase activity GO:0033673 4 0.014
cellular component biogenesis GO:0044085 178 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
response to wounding GO:0009611 116 0.014
regulation of neuron differentiation GO:0045664 56 0.014
gtp catabolic process GO:0006184 2 0.014
multi organism process GO:0051704 134 0.014
atp catabolic process GO:0006200 4 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
protein complex disassembly GO:0043241 1 0.014
macromolecular complex disassembly GO:0032984 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
action potential GO:0001508 19 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
positive regulation of reproductive process GO:2000243 2 0.014
cellular response to organic substance GO:0071310 105 0.014
oxoacid metabolic process GO:0043436 31 0.014
positive regulation of exocytosis GO:0045921 1 0.014
camera type eye morphogenesis GO:0048593 108 0.014
positive regulation of protein polymerization GO:0032273 2 0.014
organelle organization GO:0006996 227 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
protein secretion GO:0009306 1 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
sensory organ morphogenesis GO:0090596 200 0.014
protein import GO:0017038 3 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
maintenance of location GO:0051235 4 0.013
hormone transport GO:0009914 2 0.013
multicellular organismal response to stress GO:0033555 2 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
ear development GO:0043583 127 0.013
immune system development GO:0002520 191 0.013
determination of left right symmetry GO:0007368 179 0.013
regulation of endocrine process GO:0044060 2 0.013
immune system process GO:0002376 241 0.013
pronuclear migration GO:0035046 1 0.013
regulation of cell projection organization GO:0031344 44 0.013
interspecies interaction between organisms GO:0044419 4 0.013
cell projection morphogenesis GO:0048858 244 0.013
establishment of endothelial barrier GO:0061028 3 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
cellular response to starvation GO:0009267 1 0.013
cell substrate adherens junction assembly GO:0007045 1 0.013
actin filament based process GO:0030029 64 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
cell substrate junction assembly GO:0007044 2 0.013
cellular ketone metabolic process GO:0042180 11 0.012
nuclear import GO:0051170 3 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
zymogen activation GO:0031638 3 0.012
chemosensory behavior GO:0007635 1 0.012
response to growth factor GO:0070848 39 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
intracellular mrna localization GO:0008298 1 0.012
response to hexose GO:0009746 3 0.012
positive regulation of biological process GO:0048518 253 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
protein metabolic process GO:0019538 183 0.012
regulation of localization GO:0032879 104 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
protein import into nucleus GO:0006606 3 0.012
regulation of oligodendrocyte differentiation GO:0048713 1 0.012
regulation of binding GO:0051098 3 0.012
nuclear export GO:0051168 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
hemopoiesis GO:0030097 183 0.012
microtubule based movement GO:0007018 33 0.012
actin filament based movement GO:0030048 1 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
cellular protein catabolic process GO:0044257 4 0.012
regulation of wound healing GO:0061041 2 0.012
rna transport GO:0050658 2 0.012
gastrulation GO:0007369 208 0.012
post golgi vesicle mediated transport GO:0006892 1 0.012
retina development in camera type eye GO:0060041 146 0.012
hormone secretion GO:0046879 2 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
mechanosensory behavior GO:0007638 2 0.011
cellular response to growth factor stimulus GO:0071363 39 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
neuromast development GO:0048884 46 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
regulation of hormone secretion GO:0046883 2 0.011
response to organic substance GO:0010033 153 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
apical junction assembly GO:0043297 1 0.011
synaptic vesicle recycling GO:0036465 1 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
adult behavior GO:0030534 2 0.011
positive regulation of wound healing GO:0090303 1 0.011
response to glucose GO:0009749 3 0.011
cellular macromolecule metabolic process GO:0044260 391 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
vesicle localization GO:0051648 27 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
programmed cell death GO:0012501 119 0.011
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
lamellipodium assembly GO:0030032 1 0.011
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.011
negative regulation of synapse assembly GO:0051964 2 0.010
positive regulation of multicellular organismal process GO:0051240 52 0.010
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.010
cellular component assembly GO:0022607 170 0.010
neuron differentiation GO:0030182 353 0.010
carbohydrate derivative metabolic process GO:1901135 61 0.010
organic acid metabolic process GO:0006082 31 0.010
embryonic heart tube development GO:0035050 133 0.010
formation of primary germ layer GO:0001704 62 0.010
regulation of cardiac muscle contraction GO:0055117 2 0.010
female sex differentiation GO:0046660 4 0.010
endosomal transport GO:0016197 2 0.010
response to alkaloid GO:0043279 2 0.010
single organism nuclear import GO:1902593 3 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
head development GO:0060322 303 0.010
protein targeting to nucleus GO:0044744 3 0.010
cell matrix adhesion GO:0007160 4 0.010
transmission of nerve impulse GO:0019226 19 0.010

pppde2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.013