Danio rerio

37 known processes

plekha7

pleckstrin homology domain containing, family A member 7

(Aliases: si:dkey-29p10.1)

plekha7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of heart left right asymmetry GO:0061371 117 0.692
determination of left right symmetry GO:0007368 179 0.492
heart jogging GO:0003146 40 0.408
embryonic heart tube morphogenesis GO:0003143 108 0.390
specification of symmetry GO:0009799 204 0.356
morphogenesis of an epithelium GO:0002009 333 0.354
embryonic heart tube development GO:0035050 133 0.285
determination of bilateral symmetry GO:0009855 204 0.274
heart looping GO:0001947 94 0.237
heart development GO:0007507 313 0.230
cellular component morphogenesis GO:0032989 336 0.221
tube morphogenesis GO:0035239 349 0.219
embryonic organ morphogenesis GO:0048562 274 0.193
embryonic organ development GO:0048568 381 0.192
heart morphogenesis GO:0003007 156 0.191
cell projection organization GO:0030030 284 0.154
cellular component assembly GO:0022607 170 0.130
muscle structure development GO:0061061 196 0.117
nucleic acid metabolic process GO:0090304 244 0.115
muscle tissue development GO:0060537 110 0.103
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.093
adult behavior GO:0030534 2 0.090
digestive tract development GO:0048565 265 0.081
epithelial tube morphogenesis GO:0060562 148 0.080
blood circulation GO:0008015 87 0.079
digestive system development GO:0055123 289 0.079
digestive tract morphogenesis GO:0048546 231 0.079
striated muscle tissue development GO:0014706 110 0.077
larval development GO:0002164 2 0.075
cellular aromatic compound metabolic process GO:0006725 295 0.074
convergent extension involved in gastrulation GO:0060027 71 0.071
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.066
synaptic growth at neuromuscular junction GO:0051124 2 0.066
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.063
heart process GO:0003015 71 0.059
cell surface receptor signaling pathway GO:0007166 325 0.058
sensory organ development GO:0007423 393 0.055
cell part morphogenesis GO:0032990 246 0.054
cellular component biogenesis GO:0044085 178 0.052
cellular component assembly involved in morphogenesis GO:0010927 107 0.051
cell motility GO:0048870 244 0.051
chemosensory behavior GO:0007635 1 0.047
regulation of rna biosynthetic process GO:2001141 213 0.047
atrial ventricular junction remodeling GO:0003294 2 0.046
cardiac conduction system development GO:0003161 1 0.045
system process GO:0003008 185 0.045
regulation of macromolecule biosynthetic process GO:0010556 225 0.045
gene expression GO:0010467 252 0.045
regulation of cardiac muscle tissue development GO:0055024 1 0.044
startle response GO:0001964 4 0.044
positive regulation of blood circulation GO:1903524 2 0.043
regulation of synapse assembly GO:0051963 3 0.043
rna biosynthetic process GO:0032774 181 0.043
regulation of oocyte development GO:0060281 3 0.043
heart field specification GO:0003128 1 0.043
regulation of system process GO:0044057 40 0.042
cardiac chamber formation GO:0003207 4 0.041
retina development in camera type eye GO:0060041 146 0.041
cell migration involved in heart development GO:0060973 22 0.040
regulation of synapse organization GO:0050807 3 0.040
regulation of developmental process GO:0050793 247 0.040
cell morphogenesis GO:0000902 289 0.039
signal transduction GO:0007165 455 0.039
rna metabolic process GO:0016070 219 0.039
regulation of protein complex assembly GO:0043254 3 0.038
positive regulation of transport GO:0051050 2 0.037
regulation of cell projection assembly GO:0060491 4 0.037
nucleic acid templated transcription GO:0097659 181 0.037
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.037
central nervous system development GO:0007417 387 0.036
heart contraction GO:0060047 71 0.036
brain development GO:0007420 293 0.035
regulation of macromolecule metabolic process GO:0060255 317 0.035
muscle organ development GO:0007517 101 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
neuron differentiation GO:0030182 353 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
axon development GO:0061564 166 0.034
organelle assembly GO:0070925 110 0.033
outflow tract morphogenesis GO:0003151 1 0.033
convergent extension GO:0060026 118 0.032
single organism organelle organization GO:1902589 199 0.032
stem cell maintenance GO:0019827 4 0.032
regulation of transporter activity GO:0032409 2 0.032
regulation of primary metabolic process GO:0080090 311 0.032
heterocycle metabolic process GO:0046483 290 0.032
ventricular cardiac muscle tissue development GO:0003229 3 0.032
striated muscle cell differentiation GO:0051146 129 0.032
stem cell differentiation GO:0048863 117 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
neuron projection development GO:0031175 180 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
hard palate development GO:0060022 4 0.031
circulatory system process GO:0003013 87 0.031
cardiac chamber development GO:0003205 19 0.030
appendage development GO:0048736 80 0.030
regulation of transmembrane transporter activity GO:0022898 2 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.030
skeletal muscle organ development GO:0060538 78 0.030
regulation of cell shape GO:0008360 1 0.030
response to external stimulus GO:0009605 264 0.030
cell projection morphogenesis GO:0048858 244 0.029
inner ear development GO:0048839 126 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
regulation of stem cell differentiation GO:2000736 4 0.029
positive regulation of heart contraction GO:0045823 2 0.029
organonitrogen compound metabolic process GO:1901564 74 0.029
neurotransmitter transport GO:0006836 2 0.029
regulation of filopodium assembly GO:0051489 2 0.029
macromolecule biosynthetic process GO:0009059 227 0.029
negative regulation of blood circulation GO:1903523 2 0.028
cardiac chamber morphogenesis GO:0003206 12 0.028
segmentation GO:0035282 97 0.028
regulation of cardiac muscle cell differentiation GO:2000725 1 0.028
aging GO:0007568 2 0.027
negative regulation of protein complex assembly GO:0031333 1 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.026
glial cell migration GO:0008347 3 0.026
regulation of actin filament based movement GO:1903115 1 0.026
regulation of blood pressure GO:0008217 1 0.026
organelle organization GO:0006996 227 0.026
regulation of reproductive process GO:2000241 4 0.026
lipid storage GO:0019915 1 0.026
head development GO:0060322 303 0.026
ribonucleoside monophosphate catabolic process GO:0009158 4 0.026
cardiac muscle tissue development GO:0048738 48 0.025
maintenance of location GO:0051235 4 0.025
action potential GO:0001508 19 0.025
cardiac atrium morphogenesis GO:0003209 2 0.025
small gtpase mediated signal transduction GO:0007264 8 0.025
small molecule catabolic process GO:0044282 3 0.025
regulation of protein binding GO:0043393 3 0.024
regulation of rna metabolic process GO:0051252 224 0.024
actin filament based movement GO:0030048 1 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
localization of cell GO:0051674 244 0.023
cytoskeleton organization GO:0007010 96 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
regulation of blood circulation GO:1903522 32 0.023
membrane hyperpolarization GO:0060081 1 0.023
gtp catabolic process GO:0006184 2 0.023
locomotion GO:0040011 313 0.023
actin filament based process GO:0030029 64 0.022
phosphate containing compound metabolic process GO:0006796 108 0.022
response to antibiotic GO:0046677 1 0.022
regulation of organelle assembly GO:1902115 4 0.022
negative regulation of stem cell differentiation GO:2000737 2 0.022
cell projection assembly GO:0030031 64 0.022
myofibril assembly GO:0030239 48 0.022
endoderm development GO:0007492 49 0.021
synaptic transmission GO:0007268 35 0.021
nucleoside monophosphate catabolic process GO:0009125 4 0.021
establishment of localization GO:0051234 244 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
cardiac muscle cell differentiation GO:0055007 30 0.021
gastrulation GO:0007369 208 0.021
negative regulation of heart contraction GO:0045822 2 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
behavior GO:0007610 74 0.021
cation homeostasis GO:0055080 33 0.020
heart rudiment formation GO:0003315 5 0.020
regulation of cell activation GO:0050865 1 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
striated muscle cell development GO:0055002 108 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
protein metabolic process GO:0019538 183 0.020
nuclear import GO:0051170 3 0.020
cellular biosynthetic process GO:0044249 286 0.020
neuron projection morphogenesis GO:0048812 161 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
protein localization to nucleus GO:0034504 3 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
nuclear transport GO:0051169 4 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
positive regulation of catabolic process GO:0009896 4 0.019
regulation of calcium ion transport GO:0051924 2 0.019
muscle cell differentiation GO:0042692 139 0.019
generation of neurons GO:0048699 385 0.019
positive regulation of reproductive process GO:2000243 2 0.019
cellular component movement GO:0006928 335 0.019
cellular protein complex assembly GO:0043623 19 0.019
regulation of heart rate GO:0002027 5 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
nerve development GO:0021675 45 0.018
positive regulation of cell cycle GO:0045787 3 0.018
inner ear morphogenesis GO:0042472 63 0.018
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
cardiac muscle cell development GO:0055013 20 0.018
cilium morphogenesis GO:0060271 85 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
calcium ion import GO:0070509 4 0.018
protein dephosphorylation GO:0006470 3 0.018
meiotic nuclear division GO:0007126 4 0.018
taxis GO:0042330 109 0.018
regulation of metal ion transport GO:0010959 4 0.018
regulation of skeletal muscle tissue development GO:0048641 4 0.018
fin development GO:0033333 77 0.018
catechol containing compound metabolic process GO:0009712 2 0.018
transmembrane transport GO:0055085 120 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
neuron neuron synaptic transmission GO:0007270 1 0.017
somatic muscle development GO:0007525 4 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
negative regulation of muscle tissue development GO:1901862 2 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
eye development GO:0001654 277 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
response to endogenous stimulus GO:0009719 83 0.017
regulation of transcription dna templated GO:0006355 213 0.017
cell cell signaling GO:0007267 52 0.017
regulation of muscle contraction GO:0006937 3 0.017
regulation of binding GO:0051098 3 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
positive regulation of striated muscle tissue development GO:0045844 1 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of circadian rhythm GO:0042752 4 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
response to hormone GO:0009725 48 0.017
cation transport GO:0006812 81 0.017
regulation of cell killing GO:0031341 2 0.016
biosynthetic process GO:0009058 294 0.016
single organism metabolic process GO:0044710 217 0.016
response to glucocorticoid GO:0051384 1 0.016
neurological system process GO:0050877 62 0.016
regulation of response to stimulus GO:0048583 269 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
cardiac muscle cell contraction GO:0086003 1 0.016
atp catabolic process GO:0006200 4 0.016
epithelial cell differentiation GO:0030855 116 0.016
ear development GO:0043583 127 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
cellular response to endogenous stimulus GO:0071495 68 0.016
regulation of gene expression GO:0010468 265 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
inorganic ion transmembrane transport GO:0098660 57 0.016
tissue remodeling GO:0048771 4 0.016
inorganic cation transmembrane transport GO:0098662 50 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
small molecule metabolic process GO:0044281 77 0.016
regionalization GO:0003002 274 0.016
response to fluid shear stress GO:0034405 2 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
negative regulation of synapse assembly GO:0051964 2 0.015
regulation of blood vessel size GO:0050880 2 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
regulation of cell communication GO:0010646 232 0.015
protein import GO:0017038 3 0.015
endoderm formation GO:0001706 29 0.015
mesenchyme development GO:0060485 127 0.015
neuron development GO:0048666 262 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
negative regulation of cellular process GO:0048523 283 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
water homeostasis GO:0030104 4 0.015
leukocyte homeostasis GO:0001776 2 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
gtp metabolic process GO:0046039 4 0.014
regulation of organ growth GO:0046620 3 0.014
cellular amine metabolic process GO:0044106 2 0.014
sensory organ morphogenesis GO:0090596 200 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
post embryonic morphogenesis GO:0009886 4 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
ras protein signal transduction GO:0007265 7 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
regulation of metabolic process GO:0019222 359 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
neuromuscular synaptic transmission GO:0007274 2 0.014
single organism localization GO:1902578 225 0.014
transport GO:0006810 220 0.014
positive regulation of cellular process GO:0048522 201 0.014
cilium assembly GO:0042384 58 0.014
positive regulation of muscle tissue development GO:1901863 1 0.014
guanosine containing compound metabolic process GO:1901068 4 0.013
specification of organ identity GO:0010092 2 0.013
response to ketone GO:1901654 1 0.013
regulation of biosynthetic process GO:0009889 250 0.013
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
response to monosaccharide GO:0034284 3 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
cardiac cell development GO:0055006 21 0.013
protein targeting to nucleus GO:0044744 3 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.013
multicellular organismal signaling GO:0035637 22 0.013
cellular amide metabolic process GO:0043603 4 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
chemotaxis GO:0006935 104 0.013
regulation of protein transport GO:0051223 3 0.013
regulation of heart morphogenesis GO:2000826 17 0.013
pigmentation GO:0043473 85 0.013
exocytosis GO:0006887 1 0.013
organic acid metabolic process GO:0006082 31 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
protein import into nucleus GO:0006606 3 0.013
apical junction assembly GO:0043297 1 0.013
regulation of cardiac muscle contraction GO:0055117 2 0.013
smooth muscle contraction GO:0006939 2 0.013
female meiotic division GO:0007143 2 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
cytokine mediated signaling pathway GO:0019221 7 0.012
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.012
amino acid transport GO:0006865 2 0.012
response to alkaloid GO:0043279 2 0.012
negative regulation of biological process GO:0048519 304 0.012
determination of ventral identity GO:0048264 21 0.012
catecholamine metabolic process GO:0006584 2 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
heart trabecula morphogenesis GO:0061384 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
response to organic substance GO:0010033 153 0.012
oxoacid metabolic process GO:0043436 31 0.012
single organism behavior GO:0044708 24 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of wound healing GO:0061041 2 0.012
rna localization GO:0006403 4 0.012
cellular component disassembly GO:0022411 1 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of heart contraction GO:0008016 32 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
protein polymerization GO:0051258 4 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
protein complex disassembly GO:0043241 1 0.012
cellular localization GO:0051641 97 0.012
fin regeneration GO:0031101 51 0.012
intracellular signal transduction GO:0035556 85 0.012
cardiac ventricle formation GO:0003211 1 0.012
actomyosin structure organization GO:0031032 53 0.012
single organism nuclear import GO:1902593 3 0.012
vasculature development GO:0001944 278 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
macromolecular complex disassembly GO:0032984 1 0.011
epiboly GO:0090504 41 0.011
cellular response to organic substance GO:0071310 105 0.011
g protein coupled receptor signaling pathway GO:0007186 74 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
olfactory bulb development GO:0021772 4 0.011
response to abiotic stimulus GO:0009628 122 0.011
regulation of signal transduction GO:0009966 225 0.011
b cell activation GO:0042113 2 0.011
regulation of heart growth GO:0060420 2 0.011
peptidyl tyrosine dephosphorylation GO:0035335 1 0.011
germ line stem cell division GO:0042078 1 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
regulation of membrane potential GO:0042391 23 0.011
transcription dna templated GO:0006351 181 0.011
rhombomere boundary formation GO:0021654 10 0.011
regulation of rho gtpase activity GO:0032319 1 0.011
cardiac atrium development GO:0003230 4 0.011
chloride transmembrane transport GO:1902476 4 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
multi organism process GO:0051704 134 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
positive regulation of cell killing GO:0031343 2 0.011
negative regulation of immune response GO:0050777 2 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
mechanoreceptor differentiation GO:0042490 37 0.011
rho protein signal transduction GO:0007266 5 0.011
membrane repolarization GO:0086009 2 0.011
atrial cardiac muscle cell development GO:0055014 4 0.011
peptide metabolic process GO:0006518 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
cellular ketone metabolic process GO:0042180 11 0.010
fatty acid catabolic process GO:0009062 1 0.010
response to steroid hormone GO:0048545 35 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
growth GO:0040007 174 0.010
regulation of cellular component movement GO:0051270 55 0.010
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.010
regeneration GO:0031099 91 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
cell substrate adhesion GO:0031589 4 0.010
mitochondrion organization GO:0007005 4 0.010
programmed cell death GO:0012501 119 0.010
cell migration GO:0016477 237 0.010
synaptic vesicle localization GO:0097479 1 0.010
lipid oxidation GO:0034440 1 0.010
ameboidal type cell migration GO:0001667 143 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
epidermis development GO:0008544 48 0.010
angiogenesis GO:0001525 158 0.010
sequestering of calcium ion GO:0051208 3 0.010
cardiac cell fate commitment GO:0060911 1 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010

plekha7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
cardiovascular system disease DOID:1287 0 0.049
myopathy DOID:423 0 0.028
muscular disease DOID:0080000 0 0.028
heart disease DOID:114 0 0.028
cardiomyopathy DOID:0050700 0 0.028
intrinsic cardiomyopathy DOID:0060036 0 0.028
musculoskeletal system disease DOID:17 0 0.028
muscle tissue disease DOID:66 0 0.028
nervous system disease DOID:863 0 0.015