Danio rerio

0 known processes

plekha3

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3

(Aliases: MGC63749,zgc:63749)

plekha3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.298
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.205
modification dependent protein catabolic process GO:0019941 3 0.160
cellular protein catabolic process GO:0044257 4 0.117
ubiquitin dependent protein catabolic process GO:0006511 3 0.112
cellular macromolecule metabolic process GO:0044260 391 0.095
modification dependent macromolecule catabolic process GO:0043632 3 0.075
aging GO:0007568 2 0.067
proteasomal protein catabolic process GO:0010498 2 0.060
cellular biosynthetic process GO:0044249 286 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
endosomal transport GO:0016197 2 0.053
hematopoietic or lymphoid organ development GO:0048534 191 0.046
maintenance of location GO:0051235 4 0.046
positive regulation of transport GO:0051050 2 0.043
regulation of primary metabolic process GO:0080090 311 0.043
cell cycle g1 s phase transition GO:0044843 1 0.043
regulation of macromolecule metabolic process GO:0060255 317 0.042
nitrogen compound metabolic process GO:0006807 319 0.042
cellular aromatic compound metabolic process GO:0006725 295 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
negative regulation of protein phosphorylation GO:0001933 4 0.037
rna metabolic process GO:0016070 219 0.036
positive regulation of catabolic process GO:0009896 4 0.035
cellular nitrogen compound biosynthetic process GO:0044271 218 0.035
signal transduction GO:0007165 455 0.034
regulation of metabolic process GO:0019222 359 0.034
double strand break repair GO:0006302 3 0.034
immune system development GO:0002520 191 0.034
amine metabolic process GO:0009308 2 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.033
homeostasis of number of cells GO:0048872 62 0.033
establishment of localization GO:0051234 244 0.033
regulation of nucleic acid templated transcription GO:1903506 213 0.032
establishment of protein localization to organelle GO:0072594 4 0.031
g1 s transition of mitotic cell cycle GO:0000082 1 0.031
regulation of reproductive process GO:2000241 4 0.030
cellular amine metabolic process GO:0044106 2 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
lipid storage GO:0019915 1 0.029
gtp metabolic process GO:0046039 4 0.028
macromolecule biosynthetic process GO:0009059 227 0.028
myeloid cell homeostasis GO:0002262 56 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
regulation of biological quality GO:0065008 263 0.026
immune system process GO:0002376 241 0.026
protein polyubiquitination GO:0000209 4 0.026
vacuolar transport GO:0007034 2 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
cell aging GO:0007569 2 0.026
organic cyclic compound metabolic process GO:1901360 301 0.025
homeostatic process GO:0042592 142 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
response to chemical GO:0042221 320 0.024
gene expression GO:0010467 252 0.024
cellular response to chemical stimulus GO:0070887 157 0.024
stem cell division GO:0017145 1 0.024
mitotic cytokinesis GO:0000281 3 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
single organism membrane fusion GO:0044801 2 0.024
carboxylic acid metabolic process GO:0019752 22 0.023
regulation of protein transport GO:0051223 3 0.023
meiotic nuclear division GO:0007126 4 0.023
meiosis i GO:0007127 1 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.022
regulation of protein ubiquitination GO:0031396 3 0.022
negative regulation of biological process GO:0048519 304 0.022
b cell activation GO:0042113 2 0.022
response to stress GO:0006950 263 0.022
response to organic substance GO:0010033 153 0.022
positive regulation of biological process GO:0048518 253 0.022
regulation of intracellular protein transport GO:0033157 3 0.021
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.021
regulation of tube size GO:0035150 2 0.021
protein localization to plasma membrane GO:0072659 1 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of gene expression GO:0010468 265 0.021
regulation of mrna processing GO:0050684 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.020
regulation of rna metabolic process GO:0051252 224 0.020
organelle assembly GO:0070925 110 0.020
response to salt stress GO:0009651 10 0.020
protein metabolic process GO:0019538 183 0.020
regulation of gtpase activity GO:0043087 2 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
rna biosynthetic process GO:0032774 181 0.019
centrosome cycle GO:0007098 1 0.019
secondary metabolic process GO:0019748 3 0.019
hemopoiesis GO:0030097 183 0.019
biosynthetic process GO:0009058 294 0.019
golgi vesicle transport GO:0048193 3 0.018
cortical cytoskeleton organization GO:0030865 1 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
cytokinesis GO:0000910 3 0.018
cellular protein metabolic process GO:0044267 129 0.018
negative regulation of cellular process GO:0048523 283 0.018
tube morphogenesis GO:0035239 349 0.018
nucleic acid metabolic process GO:0090304 244 0.018
regulation of multicellular organismal process GO:0051239 277 0.017
glial cell migration GO:0008347 3 0.017
regulation of cytokine production GO:0001817 3 0.017
organic substance biosynthetic process GO:1901576 289 0.017
regulation of hormone secretion GO:0046883 2 0.017
establishment of protein localization to vacuole GO:0072666 1 0.017
regulation of production of molecular mediator of immune response GO:0002700 1 0.017
macromolecule modification GO:0043412 111 0.017
regulation of cell activation GO:0050865 1 0.017
transcription dna templated GO:0006351 181 0.017
protein targeting to vacuole GO:0006623 1 0.017
single organism localization GO:1902578 225 0.017
centrosome organization GO:0051297 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
membrane fusion GO:0061025 2 0.017
ribosomal small subunit biogenesis GO:0042274 2 0.016
organic acid metabolic process GO:0006082 31 0.016
single organism metabolic process GO:0044710 217 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
organelle organization GO:0006996 227 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
lysosomal transport GO:0007041 2 0.016
telomere maintenance GO:0000723 1 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
b cell differentiation GO:0030183 1 0.016
regulation of cellular ph GO:0030641 1 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
single organism transport GO:0044765 206 0.016
regulation of biosynthetic process GO:0009889 250 0.016
regulation of blood pressure GO:0008217 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of signal transduction GO:0009966 225 0.016
regulation of transporter activity GO:0032409 2 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of oocyte development GO:0060281 3 0.015
regulation of organelle assembly GO:1902115 4 0.015
regulation of defense response to virus by host GO:0050691 1 0.015
protein targeting to membrane GO:0006612 1 0.015
regulation of blood vessel size GO:0050880 2 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
peptide transport GO:0015833 1 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
cellular amide metabolic process GO:0043603 4 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.015
response to vitamin GO:0033273 3 0.015
peptidyl threonine modification GO:0018210 1 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
regulation of protein catabolic process GO:0042176 1 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
positive regulation of immune effector process GO:0002699 3 0.014
stem cell proliferation GO:0072089 4 0.014
erythrocyte homeostasis GO:0034101 55 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
myeloid cell differentiation GO:0030099 86 0.014
multicellular organism growth GO:0035264 4 0.014
response to alkaloid GO:0043279 2 0.014
regulation of chromosome segregation GO:0051983 1 0.014
neurotransmitter secretion GO:0007269 2 0.014
positive regulation of cellular process GO:0048522 201 0.014
immunoglobulin production GO:0002377 1 0.014
telomere organization GO:0032200 1 0.014
mitochondrion organization GO:0007005 4 0.014
histone phosphorylation GO:0016572 2 0.014
positive regulation of translation GO:0045727 1 0.014
regulation of cell development GO:0060284 100 0.013
cellular response to organic substance GO:0071310 105 0.013
meiotic cell cycle process GO:1903046 3 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
embryonic organ development GO:0048568 381 0.013
mononuclear cell proliferation GO:0032943 1 0.013
negative regulation of response to cytokine stimulus GO:0060761 2 0.013
cell cycle process GO:0022402 53 0.013
rhombomere 5 development GO:0021571 4 0.013
astrocyte differentiation GO:0048708 1 0.013
muscle cell migration GO:0014812 4 0.013
nuclear import GO:0051170 3 0.013
chromosome organization GO:0051276 31 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
protein localization to vacuole GO:0072665 1 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
gtp catabolic process GO:0006184 2 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
nucleic acid templated transcription GO:0097659 181 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
protein k48 linked ubiquitination GO:0070936 1 0.013
cellular macromolecule catabolic process GO:0044265 12 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
maturation of ssu rrna GO:0030490 1 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
regulation of response to stimulus GO:0048583 269 0.012
dna biosynthetic process GO:0071897 3 0.012
establishment of localization in cell GO:0051649 77 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
organelle fusion GO:0048284 3 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
sequestering of calcium ion GO:0051208 3 0.012
regulation of protein metabolic process GO:0051246 56 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
protein modification process GO:0036211 100 0.012
protein import GO:0017038 3 0.012
stem cell maintenance GO:0019827 4 0.012
meiotic chromosome segregation GO:0045132 3 0.012
positive regulation of embryonic development GO:0040019 3 0.012
regulation of intracellular ph GO:0051453 1 0.012
female meiotic division GO:0007143 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
peptide metabolic process GO:0006518 1 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
heterocycle metabolic process GO:0046483 290 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
regulation of developmental process GO:0050793 247 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
toxin metabolic process GO:0009404 1 0.012
endosome to lysosome transport GO:0008333 1 0.012
protein dephosphorylation GO:0006470 3 0.012
microtubule organizing center organization GO:0031023 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
cellular response to starvation GO:0009267 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.011
transport GO:0006810 220 0.011
developmental programmed cell death GO:0010623 4 0.011
myeloid cell development GO:0061515 32 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
tissue remodeling GO:0048771 4 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
heart development GO:0007507 313 0.011
head development GO:0060322 303 0.011
regulation of organ growth GO:0046620 3 0.011
antimicrobial humoral response GO:0019730 2 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
hormone secretion GO:0046879 2 0.011
autophagy GO:0006914 4 0.011
regulation of signaling GO:0023051 235 0.011
protein import into nucleus GO:0006606 3 0.011
chromosome organization involved in meiosis GO:0070192 1 0.011
mitotic cell cycle GO:0000278 64 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
activation of mapk activity GO:0000187 3 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
sequestering of metal ion GO:0051238 3 0.010
exocytosis GO:0006887 1 0.010
double strand break repair via homologous recombination GO:0000724 1 0.010
positive regulation of cell cycle GO:0045787 3 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
erythrocyte development GO:0048821 24 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
amide biosynthetic process GO:0043604 1 0.010
negative regulation of catabolic process GO:0009895 3 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
regulation of systemic arterial blood pressure GO:0003073 1 0.010

plekha3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014