Danio rerio

0 known processes

eif2b4

eukaryotic translation initiation factor 2B, subunit 4 delta

(Aliases: si:ch211-101l18.4,zgc:110790,wu:fb54a09)

eif2b4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.268
embryo development ending in birth or egg hatching GO:0009792 271 0.243
protein metabolic process GO:0019538 183 0.189
Human
gene expression GO:0010467 252 0.119
Human
regulation of primary metabolic process GO:0080090 311 0.084
Human
cytokinesis GO:0000910 3 0.080
locomotion GO:0040011 313 0.073
single fertilization GO:0007338 3 0.072
positive regulation of catabolic process GO:0009896 4 0.066
Human
cellular protein metabolic process GO:0044267 129 0.065
Human
fertilization GO:0009566 3 0.062
mitotic dna integrity checkpoint GO:0044774 4 0.059
positive regulation of cellular component biogenesis GO:0044089 3 0.057
cellular macromolecule metabolic process GO:0044260 391 0.056
Human
neuron differentiation GO:0030182 353 0.056
organic cyclic compound metabolic process GO:1901360 301 0.055
Human
establishment of localization GO:0051234 244 0.055
biosynthetic process GO:0009058 294 0.054
Human
response to stress GO:0006950 263 0.054
mitotic g2 m transition checkpoint GO:0044818 3 0.053
small molecule metabolic process GO:0044281 77 0.053
Human
cellular aromatic compound metabolic process GO:0006725 295 0.049
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.048
Human
regulation of gene expression GO:0010468 265 0.047
aging GO:0007568 2 0.047
response to chemical GO:0042221 320 0.047
regulation of macromolecule metabolic process GO:0060255 317 0.046
regulation of biosynthetic process GO:0009889 250 0.046
nitrogen compound metabolic process GO:0006807 319 0.045
Human
organonitrogen compound metabolic process GO:1901564 74 0.045
Human
positive regulation of biological process GO:0048518 253 0.044
Human
aromatic compound biosynthetic process GO:0019438 217 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.043
Human
mitochondrion organization GO:0007005 4 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.040
lateral inhibition GO:0046331 1 0.038
macromolecule biosynthetic process GO:0009059 227 0.038
Human
regulation of protein complex assembly GO:0043254 3 0.038
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.037
protein secretion GO:0009306 1 0.036
gtp metabolic process GO:0046039 4 0.036
Human
cellular biosynthetic process GO:0044249 286 0.036
Human
programmed cell death GO:0012501 119 0.035
sensory organ development GO:0007423 393 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
tube morphogenesis GO:0035239 349 0.033
cellular component movement GO:0006928 335 0.033
mitotic g2 dna damage checkpoint GO:0007095 3 0.033
cellular protein catabolic process GO:0044257 4 0.032
regulation of multicellular organism growth GO:0040014 4 0.032
nucleoside monophosphate catabolic process GO:0009125 4 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
Human
oxoacid metabolic process GO:0043436 31 0.030
cell part morphogenesis GO:0032990 246 0.030
regulation of rna biosynthetic process GO:2001141 213 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.029
Human
heterocycle metabolic process GO:0046483 290 0.029
Human
sister chromatid cohesion GO:0007062 2 0.029
multicellular organism growth GO:0035264 4 0.029
response to topologically incorrect protein GO:0035966 2 0.028
organic substance biosynthetic process GO:1901576 289 0.028
Human
mitotic cell cycle process GO:1903047 48 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
Human
regulation of metabolic process GO:0019222 359 0.028
Human
cellular component morphogenesis GO:0032989 336 0.028
mitotic cell cycle GO:0000278 64 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
regulation of transcription dna templated GO:0006355 213 0.027
growth GO:0040007 174 0.026
death GO:0016265 121 0.026
positive regulation of transport GO:0051050 2 0.026
macromolecule modification GO:0043412 111 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
Human
lipid storage GO:0019915 1 0.026
transport GO:0006810 220 0.025
nucleic acid metabolic process GO:0090304 244 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
apoptotic process GO:0006915 116 0.025
positive regulation of protein complex assembly GO:0031334 2 0.024
g2 dna damage checkpoint GO:0031572 3 0.024
generation of neurons GO:0048699 385 0.024
response to external stimulus GO:0009605 264 0.024
cellular component biogenesis GO:0044085 178 0.024
regulation of developmental process GO:0050793 247 0.024
negative regulation of biological process GO:0048519 304 0.023
cell projection morphogenesis GO:0048858 244 0.023
mitotic dna damage checkpoint GO:0044773 4 0.023
protein acetylation GO:0006473 2 0.023
central nervous system development GO:0007417 387 0.023
Human
heterocycle biosynthetic process GO:0018130 215 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
single organism transport GO:0044765 206 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regulation of protein catabolic process GO:0042176 1 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
Human
single organism metabolic process GO:0044710 217 0.022
Human
regulation of cellular protein catabolic process GO:1903362 1 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
protein stabilization GO:0050821 2 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
Human
eye development GO:0001654 277 0.021
cell morphogenesis GO:0000902 289 0.021
positive regulation of cellular process GO:0048522 201 0.021
Human
digestive tract morphogenesis GO:0048546 231 0.020
negative regulation of cell communication GO:0010648 96 0.020
single organism localization GO:1902578 225 0.020
neuron projection morphogenesis GO:0048812 161 0.020
muscle structure development GO:0061061 196 0.020
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.020
maintenance of location GO:0051235 4 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.019
Human
multicellular organism reproduction GO:0032504 35 0.019
Human
negative regulation of protein phosphorylation GO:0001933 4 0.019
organic acid metabolic process GO:0006082 31 0.019
meiotic chromosome segregation GO:0045132 3 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
Human
purine nucleotide metabolic process GO:0006163 27 0.019
Human
carboxylic acid metabolic process GO:0019752 22 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
Human
regulation of response to extracellular stimulus GO:0032104 1 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
Human
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
Human
neuron development GO:0048666 262 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
Human
regulation of cellular biosynthetic process GO:0031326 245 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
protein modification by small protein removal GO:0070646 1 0.017
developmental programmed cell death GO:0010623 4 0.017
axonogenesis GO:0007409 152 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
autophagy GO:0006914 4 0.017
nucleic acid templated transcription GO:0097659 181 0.017
protein modification process GO:0036211 100 0.017
single organism biosynthetic process GO:0044711 71 0.017
cell death GO:0008219 121 0.017
cellular response to nutrient levels GO:0031669 2 0.017
positive regulation of transcription dna templated GO:0045893 57 0.016
atp catabolic process GO:0006200 4 0.016
compound eye development GO:0048749 2 0.016
developmental growth GO:0048589 166 0.016
nucleotide metabolic process GO:0009117 28 0.016
Human
localization of cell GO:0051674 244 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
phagocytosis GO:0006909 3 0.016
gtp catabolic process GO:0006184 2 0.016
Human
female sex differentiation GO:0046660 4 0.016
Human
multi organism process GO:0051704 134 0.015
meiotic nuclear division GO:0007126 4 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
positive regulation of dna templated transcription elongation GO:0032786 1 0.015
response to alkaloid GO:0043279 2 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
regulation of synapse organization GO:0050807 3 0.015
spindle assembly GO:0051225 2 0.015
nuclear migration GO:0007097 3 0.015
cellular protein modification process GO:0006464 100 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
cell projection organization GO:0030030 284 0.015
positive regulation of cell cycle GO:0045787 3 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of rna metabolic process GO:0051252 224 0.015
regionalization GO:0003002 274 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
Human
cellular amino acid metabolic process GO:0006520 7 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
phosphorus metabolic process GO:0006793 109 0.014
Human
cellular amine metabolic process GO:0044106 2 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
purine containing compound metabolic process GO:0072521 29 0.014
Human
cellular response to chemical stimulus GO:0070887 157 0.014
head development GO:0060322 303 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
protein acylation GO:0043543 3 0.014
somitogenesis GO:0001756 87 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
Human
transcription dna templated GO:0006351 181 0.014
negative regulation of cellular process GO:0048523 283 0.014
regulation of mitotic cell cycle GO:0007346 25 0.014
dna templated transcription elongation GO:0006354 3 0.014
ribonucleotide metabolic process GO:0009259 27 0.014
Human
ncrna catabolic process GO:0034661 1 0.014
signal transduction GO:0007165 455 0.014
amine metabolic process GO:0009308 2 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.013
multi organism reproductive process GO:0044703 36 0.013
meiotic cell cycle process GO:1903046 3 0.013
system process GO:0003008 185 0.013
Human
positive regulation of gene expression GO:0010628 71 0.013
cellular response to stress GO:0033554 62 0.013
regulation of synapse assembly GO:0051963 3 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
neuron projection development GO:0031175 180 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of cell death GO:0010941 103 0.013
segmentation GO:0035282 97 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
protein localization to plasma membrane GO:0072659 1 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
translational initiation GO:0006413 3 0.012
Human
proteasomal protein catabolic process GO:0010498 2 0.012
regulation of chromosome segregation GO:0051983 1 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
mitochondrion morphogenesis GO:0070584 2 0.012
cell cycle GO:0007049 93 0.012
reproduction GO:0000003 40 0.012
Human
positive regulation of secretion GO:0051047 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
rna metabolic process GO:0016070 219 0.012
negative regulation of metabolic process GO:0009892 86 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
cellular response to external stimulus GO:0071496 2 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
Human
camera type eye development GO:0043010 222 0.012
regulation of cell activation GO:0050865 1 0.012
organophosphate metabolic process GO:0019637 37 0.011
Human
cellular response to oxygen levels GO:0071453 1 0.011
cellular component disassembly GO:0022411 1 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
response to drug GO:0042493 3 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
toxin transport GO:1901998 2 0.011
proteolysis GO:0006508 38 0.011
multicellular organismal reproductive process GO:0048609 35 0.011
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
eye morphogenesis GO:0048592 144 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
negative regulation of kinase activity GO:0033673 4 0.011
anterior posterior pattern specification GO:0009952 152 0.011
transmembrane transport GO:0055085 120 0.011
regulation of cytokine production GO:0001817 3 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
regulation of protein targeting GO:1903533 2 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
negative regulation of signaling GO:0023057 96 0.011
mitotic nuclear division GO:0007067 18 0.011
rrna catabolic process GO:0016075 1 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of signal transduction GO:0009966 225 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
Human
regulation of protein metabolic process GO:0051246 56 0.010
protein dephosphorylation GO:0006470 3 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
Human
mitotic cell cycle phase transition GO:0044772 9 0.010
cellular localization GO:0051641 97 0.010
somite development GO:0061053 96 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.010
leukocyte proliferation GO:0070661 1 0.010
cell cell recognition GO:0009988 1 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
amino acid transport GO:0006865 2 0.010
sensory organ morphogenesis GO:0090596 200 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
intestinal absorption GO:0050892 2 0.010
mitotic cytokinesis GO:0000281 3 0.010

eif2b4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.016
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
neuromuscular disease DOID:440 0 0.011
charcot marie tooth disease DOID:10595 0 0.011
neuropathy DOID:870 0 0.011
musculoskeletal system disease DOID:17 0 0.011