Danio rerio

0 known processes

piga

phosphatidylinositol glycan anchor biosynthesis, class A

(Aliases: zgc:56589,MGC56589,im:6911675)

piga biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 181 0.105
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.081
larval development GO:0002164 2 0.075
biosynthetic process GO:0009058 294 0.060
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.059
Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.056
adult behavior GO:0030534 2 0.052
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.051
meiotic nuclear division GO:0007126 4 0.050
positive regulation of catabolic process GO:0009896 4 0.049
modification dependent macromolecule catabolic process GO:0043632 3 0.048
nucleic acid metabolic process GO:0090304 244 0.048
modification dependent protein catabolic process GO:0019941 3 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.048
organic cyclic compound biosynthetic process GO:1901362 223 0.046
rna metabolic process GO:0016070 219 0.043
positive regulation of cellular catabolic process GO:0031331 3 0.042
proteasomal protein catabolic process GO:0010498 2 0.041
heterocycle metabolic process GO:0046483 290 0.041
cellular protein catabolic process GO:0044257 4 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.040
regulation of biosynthetic process GO:0009889 250 0.039
embryonic organ development GO:0048568 381 0.039
organelle fusion GO:0048284 3 0.038
nuclear export GO:0051168 1 0.038
regulation of protein ubiquitination GO:0031396 3 0.038
centrosome cycle GO:0007098 1 0.037
organic cyclic compound metabolic process GO:1901360 301 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.036
cellular macromolecule biosynthetic process GO:0034645 224 0.036
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.036
regulation of establishment of protein localization GO:0070201 4 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
organic substance biosynthetic process GO:1901576 289 0.032
Mouse
regulation of transcription dna templated GO:0006355 213 0.032
nitrogen compound metabolic process GO:0006807 319 0.031
signal transduction GO:0007165 455 0.030
aging GO:0007568 2 0.030
regulation of cell communication GO:0010646 232 0.030
regulation of protein transport GO:0051223 3 0.030
positive regulation of metabolic process GO:0009893 108 0.030
regulation of biological quality GO:0065008 263 0.030
single organism organelle organization GO:1902589 199 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.030
gene expression GO:0010467 252 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
transcription dna templated GO:0006351 181 0.029
cellular biosynthetic process GO:0044249 286 0.028
Mouse
regulation of protein catabolic process GO:0042176 1 0.028
regulation of rna metabolic process GO:0051252 224 0.028
nuclear import GO:0051170 3 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
regulation of synaptic plasticity GO:0048167 1 0.027
positive regulation of transport GO:0051050 2 0.027
cellular amine metabolic process GO:0044106 2 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
rna modification GO:0009451 2 0.026
head development GO:0060322 303 0.026
regulation of signal transduction GO:0009966 225 0.026
protein localization to plasma membrane GO:0072659 1 0.026
maintenance of location GO:0051235 4 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
programmed cell death GO:0012501 119 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
regulation of chromosome segregation GO:0051983 1 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
regulation of metabolic process GO:0019222 359 0.025
macromolecule modification GO:0043412 111 0.024
Mouse
regulation of reproductive process GO:2000241 4 0.024
regulation of erk1 and erk2 cascade GO:0070372 4 0.024
rna biosynthetic process GO:0032774 181 0.024
protein polyubiquitination GO:0000209 4 0.024
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
stem cell proliferation GO:0072089 4 0.023
membrane fusion GO:0061025 2 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
oxoacid metabolic process GO:0043436 31 0.023
autophagy GO:0006914 4 0.023
peptidyl threonine modification GO:0018210 1 0.023
regulation of organelle assembly GO:1902115 4 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
erk1 and erk2 cascade GO:0070371 4 0.022
organelle organization GO:0006996 227 0.022
nuclear transport GO:0051169 4 0.022
endosome organization GO:0007032 2 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
regulation of binding GO:0051098 3 0.022
peptide transport GO:0015833 1 0.021
death GO:0016265 121 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
cellular response to lipopolysaccharide GO:0071222 3 0.021
cellular ketone metabolic process GO:0042180 11 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
catecholamine metabolic process GO:0006584 2 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.021
single organism metabolic process GO:0044710 217 0.021
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.021
response to antibiotic GO:0046677 1 0.021
amine metabolic process GO:0009308 2 0.021
stem cell division GO:0017145 1 0.021
cellular amino acid metabolic process GO:0006520 7 0.020
negative regulation of mapk cascade GO:0043409 4 0.020
vacuolar transport GO:0007034 2 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
protein import into nucleus GO:0006606 3 0.020
cell motility GO:0048870 244 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.019
cellular response to external stimulus GO:0071496 2 0.019
response to nutrient GO:0007584 3 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
apoptotic process GO:0006915 116 0.019
response to external stimulus GO:0009605 264 0.019
dicarboxylic acid metabolic process GO:0043648 1 0.019
tube morphogenesis GO:0035239 349 0.019
regulation of primary metabolic process GO:0080090 311 0.019
regulation of synapse assembly GO:0051963 3 0.018
protein dephosphorylation GO:0006470 3 0.018
positive regulation of cellular process GO:0048522 201 0.018
cellular response to nutrient levels GO:0031669 2 0.018
single organism membrane fusion GO:0044801 2 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
female sex differentiation GO:0046660 4 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
brain development GO:0007420 293 0.018
negative regulation of gliogenesis GO:0014014 1 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
single organism nuclear import GO:1902593 3 0.018
positive regulation of epithelial cell proliferation GO:0050679 1 0.018
cellular component movement GO:0006928 335 0.018
protein localization to nucleus GO:0034504 3 0.018
protein import GO:0017038 3 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
protein polymerization GO:0051258 4 0.018
response to hexose GO:0009746 3 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
neuroblast proliferation GO:0007405 2 0.017
locomotor rhythm GO:0045475 3 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
homeostasis of number of cells GO:0048872 62 0.017
centrosome organization GO:0051297 1 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
toxin transport GO:1901998 2 0.017
golgi vesicle transport GO:0048193 3 0.017
microtubule organizing center organization GO:0031023 1 0.017
phagocytosis GO:0006909 3 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
glucose homeostasis GO:0042593 1 0.017
developmental programmed cell death GO:0010623 4 0.017
mononuclear cell proliferation GO:0032943 1 0.017
forebrain cell migration GO:0021885 1 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
Mouse
compound eye development GO:0048749 2 0.016
regulation of circadian rhythm GO:0042752 4 0.016
regulation of protein complex assembly GO:0043254 3 0.016
cell matrix adhesion GO:0007160 4 0.016
b cell activation GO:0042113 2 0.016
regulation of cytokine production GO:0001817 3 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
regulation of cell activation GO:0050865 1 0.016
exocytosis GO:0006887 1 0.016
positive regulation of biological process GO:0048518 253 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
homeostatic process GO:0042592 142 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
leukocyte proliferation GO:0070661 1 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
pronephros development GO:0048793 69 0.016
hatching GO:0035188 4 0.015
response to carbohydrate GO:0009743 3 0.015
generation of neurons GO:0048699 385 0.015
locomotion GO:0040011 313 0.015
central nervous system development GO:0007417 387 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
negative regulation of cellular process GO:0048523 283 0.015
cellular amide metabolic process GO:0043603 4 0.015
negative regulation of protein transport GO:0051224 3 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
cell morphogenesis GO:0000902 289 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cell migration GO:0016477 237 0.014
lymphocyte proliferation GO:0046651 1 0.014
nik nf kappab signaling GO:0038061 1 0.014
cellular protein metabolic process GO:0044267 129 0.014
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
membrane invagination GO:0010324 1 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
meiotic cell cycle process GO:1903046 3 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
response to stress GO:0006950 263 0.014
macroautophagy GO:0016236 1 0.014
regulation of signaling GO:0023051 235 0.014
hormone transport GO:0009914 2 0.014
peptidyl serine modification GO:0018209 2 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
rna localization GO:0006403 4 0.014
adherens junction organization GO:0034332 4 0.014
cell aging GO:0007569 2 0.014
heart development GO:0007507 313 0.014
regulation of synapse organization GO:0050807 3 0.013
hematopoietic stem cell migration GO:0035701 4 0.013
establishment of localization GO:0051234 244 0.013
apoptotic process involved in development GO:1902742 2 0.013
double strand break repair GO:0006302 3 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
carbohydrate homeostasis GO:0033500 1 0.013
cell projection morphogenesis GO:0048858 244 0.013
response to monosaccharide GO:0034284 3 0.013
indole containing compound metabolic process GO:0042430 2 0.013
cytokinesis GO:0000910 3 0.013
stem cell maintenance GO:0019827 4 0.013
cognition GO:0050890 1 0.013
regulation of jak stat cascade GO:0046425 3 0.013
protein stabilization GO:0050821 2 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
catechol containing compound metabolic process GO:0009712 2 0.013
single organism transport GO:0044765 206 0.013
lipid storage GO:0019915 1 0.013
single organism localization GO:1902578 225 0.013
regulation of protein targeting GO:1903533 2 0.013
regulation of apoptotic process GO:0042981 98 0.013
regulation of inflammatory response GO:0050727 2 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
cellular response to starvation GO:0009267 1 0.013
negative regulation of biological process GO:0048519 304 0.013
regulation of response to stimulus GO:0048583 269 0.013
meiosis i GO:0007127 1 0.013
positive regulation of cell cycle GO:0045787 3 0.013
regulation of cell shape GO:0008360 1 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
negative regulation of nuclear division GO:0051784 3 0.013
cell substrate adhesion GO:0031589 4 0.013
synaptic vesicle localization GO:0097479 1 0.013
protein modification by small protein conjugation or removal GO:0070647 14 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
positive regulation of rna biosynthetic process GO:1902680 57 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
primary neural tube formation GO:0014020 1 0.013
rna export from nucleus GO:0006405 1 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
actin filament polymerization GO:0030041 2 0.013
lymphocyte homeostasis GO:0002260 1 0.012
organic acid metabolic process GO:0006082 31 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
establishment of protein localization to vacuole GO:0072666 1 0.012
response to corticosteroid GO:0031960 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
leukocyte homeostasis GO:0001776 2 0.012
multicellular organism growth GO:0035264 4 0.012
endosomal transport GO:0016197 2 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
regulation of gene expression GO:0010468 265 0.012
hormone secretion GO:0046879 2 0.012
protein metabolic process GO:0019538 183 0.012
Mouse
positive regulation of cell activation GO:0050867 1 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
localization of cell GO:0051674 244 0.012
centrosome duplication GO:0051298 1 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
lens fiber cell development GO:0070307 3 0.012
cellular response to light stimulus GO:0071482 4 0.012
neuron differentiation GO:0030182 353 0.012
glial cell proliferation GO:0014009 4 0.012
intracellular signal transduction GO:0035556 85 0.012
protein k48 linked ubiquitination GO:0070936 1 0.012
positive regulation of histone modification GO:0031058 1 0.012
cell projection organization GO:0030030 284 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
somatic stem cell maintenance GO:0035019 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
erythrocyte homeostasis GO:0034101 55 0.011
eye development GO:0001654 277 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
tube closure GO:0060606 1 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
regulation of protein binding GO:0043393 3 0.011
secondary metabolic process GO:0019748 3 0.011
chemosensory behavior GO:0007635 1 0.011
nucleic acid transport GO:0050657 2 0.011
erythrocyte development GO:0048821 24 0.011
response to glucocorticoid GO:0051384 1 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
protein acylation GO:0043543 3 0.011
protein modification process GO:0036211 100 0.011
Mouse
neuron projection morphogenesis GO:0048812 161 0.011
sensory organ morphogenesis GO:0090596 200 0.011
negative regulation of kinase activity GO:0033673 4 0.011
germ line stem cell maintenance GO:0030718 2 0.011
cellular component assembly GO:0022607 170 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
regulation of cell aging GO:0090342 1 0.011
positive regulation of cytokine production GO:0001819 2 0.011
organism emergence from protective structure GO:0071684 4 0.011
phototransduction GO:0007602 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
dicarboxylic acid transport GO:0006835 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of signal transduction GO:0009967 56 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.011
transport GO:0006810 220 0.011
regulation of protein polymerization GO:0032271 2 0.011
sequestering of calcium ion GO:0051208 3 0.011
negative regulation of defense response GO:0031348 2 0.011
positive regulation of secretion GO:0051047 1 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
synaptic vesicle transport GO:0048489 1 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
response to ketone GO:1901654 1 0.010
small molecule metabolic process GO:0044281 77 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
negative regulation of response to cytokine stimulus GO:0060761 2 0.010
fertilization GO:0009566 3 0.010
cellular response to hormone stimulus GO:0032870 39 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010
female gonad development GO:0008585 4 0.010
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.010
skeletal system development GO:0001501 181 0.010
negative regulation of cell death GO:0060548 60 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
cellular component morphogenesis GO:0032989 336 0.010
muscle cell migration GO:0014812 4 0.010
cell death GO:0008219 121 0.010
response to glucose GO:0009749 3 0.010
mitotic cell cycle GO:0000278 64 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
single fertilization GO:0007338 3 0.010
cellular response to radiation GO:0071478 4 0.010
cellular component maintenance GO:0043954 3 0.010
regulation of organ growth GO:0046620 3 0.010
multi organism process GO:0051704 134 0.010
tissue remodeling GO:0048771 4 0.010
sequestering of metal ion GO:0051238 3 0.010

piga disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
disease of anatomical entity DOID:7 0 0.028
musculoskeletal system disease DOID:17 0 0.014