Danio rerio

15 known processes

pdcd4b

programmed cell death 4b

(Aliases: pdcd4,sb:cb45,cb45,wu:fc84b08)

pdcd4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.191
Human
larval development GO:0002164 2 0.139
immune system process GO:0002376 241 0.129
stem cell proliferation GO:0072089 4 0.098
organic cyclic compound biosynthetic process GO:1901362 223 0.097
Human
response to stress GO:0006950 263 0.095
cellular macromolecule metabolic process GO:0044260 391 0.087
Human
single organism metabolic process GO:0044710 217 0.083
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.082
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.080
Human
negative regulation of protein phosphorylation GO:0001933 4 0.080
reactive nitrogen species metabolic process GO:2001057 0 0.079
cell morphogenesis GO:0000902 289 0.070
morphogenesis of an epithelium GO:0002009 333 0.069
nitrogen compound metabolic process GO:0006807 319 0.068
Human
cellular protein metabolic process GO:0044267 129 0.065
positive regulation of transport GO:0051050 2 0.064
protein metabolic process GO:0019538 183 0.062
cellular nitrogen compound biosynthetic process GO:0044271 218 0.060
Human
biosynthetic process GO:0009058 294 0.058
Human
positive regulation of biological process GO:0048518 253 0.058
regulation of gene expression GO:0010468 265 0.056
Human
eye development GO:0001654 277 0.054
response to external stimulus GO:0009605 264 0.052
organic substance biosynthetic process GO:1901576 289 0.052
Human
tube morphogenesis GO:0035239 349 0.050
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
Human
nucleoside monophosphate catabolic process GO:0009125 4 0.047
digestive tract morphogenesis GO:0048546 231 0.047
response to chemical GO:0042221 320 0.046
regulation of primary metabolic process GO:0080090 311 0.046
Human
regulation of stem cell proliferation GO:0072091 2 0.045
cellular aromatic compound metabolic process GO:0006725 295 0.044
Human
generation of neurons GO:0048699 385 0.044
regulation of macromolecule metabolic process GO:0060255 317 0.044
Human
regulation of cell shape GO:0008360 1 0.044
organic cyclic compound metabolic process GO:1901360 301 0.043
Human
positive regulation of cellular process GO:0048522 201 0.043
central nervous system development GO:0007417 387 0.043
digestive tract development GO:0048565 265 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
heterocycle metabolic process GO:0046483 290 0.040
Human
sensory organ development GO:0007423 393 0.040
neuron differentiation GO:0030182 353 0.039
regulation of cellular metabolic process GO:0031323 320 0.039
Human
regulation of protein polymerization GO:0032271 2 0.039
cell cycle g1 s phase transition GO:0044843 1 0.039
negative regulation of protein kinase activity GO:0006469 4 0.038
aromatic compound biosynthetic process GO:0019438 217 0.038
Human
positive regulation of map kinase activity GO:0043406 3 0.038
rna metabolic process GO:0016070 219 0.038
Human
maintenance of location GO:0051235 4 0.037
mitotic cell cycle process GO:1903047 48 0.037
gastrulation GO:0007369 208 0.036
response to monosaccharide GO:0034284 3 0.036
regulation of anatomical structure morphogenesis GO:0022603 130 0.035
digestive system development GO:0055123 289 0.035
regulation of establishment of protein localization GO:0070201 4 0.035
meiotic nuclear division GO:0007126 4 0.034
cellular response to external stimulus GO:0071496 2 0.033
photoreceptor cell fate commitment GO:0046552 1 0.033
cell cycle GO:0007049 93 0.033
positive regulation of blood circulation GO:1903524 2 0.033
negative regulation of kinase activity GO:0033673 4 0.033
response to lipid GO:0033993 60 0.033
embryonic heart tube development GO:0035050 133 0.033
cell cycle process GO:0022402 53 0.033
blood vessel development GO:0001568 246 0.033
neuroblast proliferation GO:0007405 2 0.032
regulation of signaling GO:0023051 235 0.031
blood vessel morphogenesis GO:0048514 216 0.031
amine metabolic process GO:0009308 2 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
multicellular organismal metabolic process GO:0044236 2 0.031
hormone transport GO:0009914 2 0.030
regulation of nucleoside metabolic process GO:0009118 2 0.030
regulation of cellular biosynthetic process GO:0031326 245 0.029
Human
positive regulation of catabolic process GO:0009896 4 0.029
regulation of protein transport GO:0051223 3 0.029
protein modification process GO:0036211 100 0.029
regulation of response to stimulus GO:0048583 269 0.028
ameboidal type cell migration GO:0001667 143 0.028
g1 s transition of mitotic cell cycle GO:0000082 1 0.028
cellular ketone metabolic process GO:0042180 11 0.028
regulation of mrna processing GO:0050684 3 0.028
response to carbohydrate GO:0009743 3 0.027
cell aging GO:0007569 2 0.027
Human
retina development in camera type eye GO:0060041 146 0.027
regulation of dna templated transcription in response to stress GO:0043620 0 0.027
regulation of signal transduction GO:0009966 225 0.027
photoreceptor cell fate specification GO:0043704 1 0.027
somatic muscle development GO:0007525 4 0.027
meiotic cell cycle process GO:1903046 3 0.027
negative regulation of map kinase activity GO:0043407 2 0.027
regulation of biosynthetic process GO:0009889 250 0.027
Human
microtubule organizing center organization GO:0031023 1 0.027
determination of left right symmetry GO:0007368 179 0.027
hormone secretion GO:0046879 2 0.026
camera type eye development GO:0043010 222 0.026
nitric oxide metabolic process GO:0046209 2 0.026
centrosome organization GO:0051297 1 0.025
immunoglobulin mediated immune response GO:0016064 3 0.025
reactive oxygen species biosynthetic process GO:1903409 1 0.025
regulation of cell projection assembly GO:0060491 4 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
response to hexose GO:0009746 3 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
Human
signal transduction GO:0007165 455 0.024
cellular response to starvation GO:0009267 1 0.024
endocrine hormone secretion GO:0060986 2 0.024
cellular amine metabolic process GO:0044106 2 0.024
vasculature development GO:0001944 278 0.024
atp catabolic process GO:0006200 4 0.023
cellular response to nutrient levels GO:0031669 2 0.023
regulation of cell activation GO:0050865 1 0.023
lipid storage GO:0019915 1 0.023
regulation of developmental process GO:0050793 247 0.023
connective tissue development GO:0061448 99 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
cellular component movement GO:0006928 335 0.023
multicellular organism growth GO:0035264 4 0.023
negative regulation of mapk cascade GO:0043409 4 0.023
regulation of rho protein signal transduction GO:0035023 2 0.023
protein polymerization GO:0051258 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
Human
amino acid transport GO:0006865 2 0.022
regulation of biological quality GO:0065008 263 0.022
cellular biosynthetic process GO:0044249 286 0.022
Human
negative regulation of cellular process GO:0048523 283 0.022
Human
determination of bilateral symmetry GO:0009855 204 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
nucleic acid metabolic process GO:0090304 244 0.022
Human
positive regulation of cellular biosynthetic process GO:0031328 68 0.022
b cell activation GO:0042113 2 0.021
head development GO:0060322 303 0.021
protein acetylation GO:0006473 2 0.021
positive regulation of translation GO:0045727 1 0.021
rna localization GO:0006403 4 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
organelle organization GO:0006996 227 0.021
mononuclear cell proliferation GO:0032943 1 0.021
hepaticobiliary system development GO:0061008 98 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
pericardium development GO:0060039 1 0.021
histone demethylation GO:0016577 2 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
astrocyte differentiation GO:0048708 1 0.020
immune system development GO:0002520 191 0.020
ventricular cardiac muscle tissue development GO:0003229 3 0.020
protein dephosphorylation GO:0006470 3 0.020
cell motility GO:0048870 244 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
regulation of protein complex assembly GO:0043254 3 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
single organism organelle organization GO:1902589 199 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
gastrulation with mouth forming second GO:0001702 44 0.020
meiosis i GO:0007127 1 0.020
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.019
macromolecule modification GO:0043412 111 0.019
reactive oxygen species metabolic process GO:0072593 6 0.019
regulation of hormone secretion GO:0046883 2 0.019
regulation of transcription dna templated GO:0006355 213 0.019
Human
regulation of reproductive process GO:2000241 4 0.019
response to amino acid GO:0043200 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
nitric oxide biosynthetic process GO:0006809 2 0.019
oxoacid metabolic process GO:0043436 31 0.019
organic acid metabolic process GO:0006082 31 0.019
positive regulation of cell cycle GO:0045787 3 0.019
mitotic cell cycle GO:0000278 64 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
limb bud formation GO:0060174 2 0.018
regulation of protein targeting GO:1903533 2 0.018
liver development GO:0001889 96 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
cellular protein modification process GO:0006464 100 0.018
regulation of wound healing GO:0061041 2 0.018
phagocytosis GO:0006909 3 0.018
pronephros development GO:0048793 69 0.018
nuclear export GO:0051168 1 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
regulation of intracellular protein transport GO:0033157 3 0.017
small molecule metabolic process GO:0044281 77 0.017
regulation of intracellular ph GO:0051453 1 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
centrosome cycle GO:0007098 1 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
Human
response to ketone GO:1901654 1 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
gtp catabolic process GO:0006184 2 0.017
heart development GO:0007507 313 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
positive regulation of signal transduction GO:0009967 56 0.017
rna biosynthetic process GO:0032774 181 0.017
Human
i kappab kinase nf kappab signaling GO:0007249 4 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
response to hydrogen peroxide GO:0042542 3 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
response to copper ion GO:0046688 13 0.016
aging GO:0007568 2 0.016
Human
defense response GO:0006952 47 0.016
positive regulation of muscle tissue development GO:1901863 1 0.016
brain development GO:0007420 293 0.016
b cell mediated immunity GO:0019724 3 0.016
single organism localization GO:1902578 225 0.016
synaptic vesicle localization GO:0097479 1 0.016
regulation of filopodium assembly GO:0051489 2 0.016
peptidyl threonine phosphorylation GO:0018107 1 0.016
eye morphogenesis GO:0048592 144 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
Human
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of circadian sleep wake cycle GO:0042749 1 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
single organism transport GO:0044765 206 0.016
response to glucose GO:0009749 3 0.016
heterocycle biosynthetic process GO:0018130 215 0.015
Human
nuclear migration GO:0007097 3 0.015
regulation of cell communication GO:0010646 232 0.015
chromosome organization involved in meiosis GO:0070192 1 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.015
lymphocyte proliferation GO:0046651 1 0.015
transport GO:0006810 220 0.015
gene expression GO:0010467 252 0.015
Human
single organism nuclear import GO:1902593 3 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
kidney development GO:0001822 92 0.015
negative regulation of protein complex assembly GO:0031333 1 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
response to organic cyclic compound GO:0014070 51 0.015
mitochondrion organization GO:0007005 4 0.015
regulation of endocrine process GO:0044060 2 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
protein dealkylation GO:0008214 2 0.014
chromosome organization GO:0051276 31 0.014
response to abiotic stimulus GO:0009628 122 0.014
actin filament polymerization GO:0030041 2 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
adherens junction maintenance GO:0034334 2 0.014
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.014
regulation of protein catabolic process GO:0042176 1 0.014
morphogenesis of an epithelial sheet GO:0002011 49 0.014
positive regulation of metabolic process GO:0009893 108 0.014
positive regulation of striated muscle tissue development GO:0045844 1 0.014
regulation of jak stat cascade GO:0046425 3 0.014
membrane invagination GO:0010324 1 0.014
transcription dna templated GO:0006351 181 0.014
Human
positive regulation of stem cell proliferation GO:2000648 1 0.014
pericardium morphogenesis GO:0003344 1 0.014
positive regulation of secretion GO:0051047 1 0.014
protein phosphorylation GO:0006468 47 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
regulation of circadian rhythm GO:0042752 4 0.014
histone modification GO:0016570 20 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
negative regulation of biological process GO:0048519 304 0.014
Human
guanosine containing compound catabolic process GO:1901069 2 0.014
positive regulation of lipid metabolic process GO:0045834 1 0.014
specification of symmetry GO:0009799 204 0.014
circadian sleep wake cycle sleep GO:0050802 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
protein targeting to nucleus GO:0044744 3 0.013
leukocyte proliferation GO:0070661 1 0.013
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.013
positive regulation of muscle organ development GO:0048636 1 0.013
regulation of cytokine production GO:0001817 3 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
circadian sleep wake cycle GO:0042745 2 0.013
negative regulation of defense response GO:0031348 2 0.013
response to inorganic substance GO:0010035 38 0.013
regulation of skeletal muscle fiber development GO:0048742 2 0.013
single organism membrane fusion GO:0044801 2 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
defense response to fungus GO:0050832 2 0.013
muscle structure development GO:0061061 196 0.013
adherens junction organization GO:0034332 4 0.013
septum transversum development GO:0003343 4 0.013
positive regulation of gene expression GO:0010628 71 0.013
response to nutrient GO:0007584 3 0.013
tissue remodeling GO:0048771 4 0.013
negative regulation of dna recombination GO:0045910 2 0.013
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.013
protein targeting to membrane GO:0006612 1 0.013
cell projection organization GO:0030030 284 0.013
epiboly GO:0090504 41 0.013
gtp metabolic process GO:0046039 4 0.013
nuclear transport GO:0051169 4 0.013
regulation of erythrocyte differentiation GO:0045646 2 0.013
posterior lateral line system development GO:0048915 46 0.013
monoamine transport GO:0015844 1 0.013
stem cell maintenance GO:0019827 4 0.013
response to drug GO:0042493 3 0.012
phosphorus metabolic process GO:0006793 109 0.012
endocrine process GO:0050886 2 0.012
regulation of transporter activity GO:0032409 2 0.012
growth GO:0040007 174 0.012
peptide transport GO:0015833 1 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
Human
programmed cell death GO:0012501 119 0.012
heart looping GO:0001947 94 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
retinal rod cell development GO:0046548 4 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
pancreas development GO:0031016 84 0.012
intracellular mrna localization GO:0008298 1 0.012
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.012
protein localization to plasma membrane GO:0072659 1 0.012
heart valve formation GO:0003188 4 0.012
nephric duct development GO:0072176 13 0.012
regulation of catalytic activity GO:0050790 55 0.012
response to vitamin GO:0033273 3 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
intracellular signal transduction GO:0035556 85 0.012
central nervous system neuron differentiation GO:0021953 74 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
autophagy GO:0006914 4 0.012
protein import into nucleus GO:0006606 3 0.012
atrioventricular valve formation GO:0003190 3 0.012
microtubule based process GO:0007017 60 0.011
spermatid development GO:0007286 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
regulation of molecular function GO:0065009 70 0.011
cell proliferation GO:0008283 80 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
Human
response to organic substance GO:0010033 153 0.011
sensory organ morphogenesis GO:0090596 200 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of blood coagulation GO:0030193 1 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
ribosomal small subunit biogenesis GO:0042274 2 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
cellular protein catabolic process GO:0044257 4 0.011
cell migration GO:0016477 237 0.011
atrioventricular valve development GO:0003171 11 0.011
regulation of binding GO:0051098 3 0.011
embryonic skeletal joint morphogenesis GO:0060272 3 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
cell cell recognition GO:0009988 1 0.011
regulation of cardiac muscle tissue development GO:0055024 1 0.011
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.011
alcohol biosynthetic process GO:0046165 2 0.011
positive regulation of signaling GO:0023056 56 0.011
ear development GO:0043583 127 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
protein complex localization GO:0031503 1 0.011
inner ear development GO:0048839 126 0.011
regulation of blood vessel size GO:0050880 2 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
mrna 3 end processing GO:0031124 2 0.011
medulla oblongata development GO:0021550 4 0.011
somite development GO:0061053 96 0.011
embryonic organ development GO:0048568 381 0.011
cardiac conduction system development GO:0003161 1 0.011
response to alkaloid GO:0043279 2 0.011
endocardium morphogenesis GO:0003160 4 0.011
regulation of vasculature development GO:1901342 33 0.010
nucleic acid templated transcription GO:0097659 181 0.010
Human
protein acylation GO:0043543 3 0.010
negative regulation of rna biosynthetic process GO:1902679 45 0.010
Human
response to uv GO:0009411 3 0.010
camera type eye morphogenesis GO:0048593 108 0.010
locomotor rhythm GO:0045475 3 0.010
cellular component morphogenesis GO:0032989 336 0.010
erythrocyte differentiation GO:0030218 54 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
lateral line system development GO:0048925 76 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
regulation of gtpase activity GO:0043087 2 0.010
neural retina development GO:0003407 49 0.010
regulation of blood pressure GO:0008217 1 0.010
protein import GO:0017038 3 0.010
regulation of receptor activity GO:0010469 2 0.010
golgi vesicle transport GO:0048193 3 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
female sex differentiation GO:0046660 4 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
regulation of myotube differentiation GO:0010830 2 0.010
wound healing GO:0042060 90 0.010
stem cell division GO:0017145 1 0.010

pdcd4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.032
disease of anatomical entity DOID:7 0 0.032
hematopoietic system disease DOID:74 0 0.028
disease of metabolism DOID:0014667 0 0.014