Danio rerio

0 known processes

tlx3b

T-cell leukemia, homeobox 3b

(Aliases: Tlx-3b,ztlx-3b)

tlx3b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.143
organic cyclic compound metabolic process GO:1901360 301 0.141
regulation of nitrogen compound metabolic process GO:0051171 251 0.135
positive regulation of biological process GO:0048518 253 0.096
regulation of macromolecule metabolic process GO:0060255 317 0.095
generation of neurons GO:0048699 385 0.089
cranial nerve development GO:0021545 42 0.088
female sex differentiation GO:0046660 4 0.083
immune system process GO:0002376 241 0.080
positive regulation of macromolecule metabolic process GO:0010604 93 0.079
locomotion GO:0040011 313 0.079
nucleobase containing compound metabolic process GO:0006139 274 0.077
compound eye development GO:0048749 2 0.076
cell morphogenesis GO:0000902 289 0.075
digestive tract development GO:0048565 265 0.075
regulation of multicellular organismal process GO:0051239 277 0.075
regulation of biological quality GO:0065008 263 0.074
appendage development GO:0048736 80 0.063
rna metabolic process GO:0016070 219 0.061
regulation of cellular metabolic process GO:0031323 320 0.061
cellular macromolecule metabolic process GO:0044260 391 0.059
response to wounding GO:0009611 116 0.059
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.055
regulation of metabolic process GO:0019222 359 0.054
central nervous system myelin formation GO:0032289 1 0.052
regulation of signal transduction GO:0009966 225 0.052
morphogenesis of an epithelium GO:0002009 333 0.049
gastrulation GO:0007369 208 0.048
cellular response to stress GO:0033554 62 0.048
fin development GO:0033333 77 0.047
cellular component morphogenesis GO:0032989 336 0.046
embryonic organ morphogenesis GO:0048562 274 0.046
larval development GO:0002164 2 0.046
regulation of primary metabolic process GO:0080090 311 0.045
central nervous system development GO:0007417 387 0.045
regulation of rna metabolic process GO:0051252 224 0.044
positive regulation of epithelial cell differentiation GO:0030858 2 0.044
negative regulation of protein phosphorylation GO:0001933 4 0.044
single organism organelle organization GO:1902589 199 0.044
chordate embryonic development GO:0043009 271 0.043
organic cyclic compound biosynthetic process GO:1901362 223 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.043
photoreceptor cell fate specification GO:0043704 1 0.043
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.042
neuron projection development GO:0031175 180 0.041
cell morphogenesis involved in differentiation GO:0000904 195 0.041
transcription dna templated GO:0006351 181 0.041
nucleic acid metabolic process GO:0090304 244 0.040
skeletal system development GO:0001501 181 0.040
response to stress GO:0006950 263 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.039
nerve development GO:0021675 45 0.039
head development GO:0060322 303 0.038
regulation of signaling GO:0023051 235 0.038
heterocycle biosynthetic process GO:0018130 215 0.038
system process GO:0003008 185 0.038
neuron differentiation GO:0030182 353 0.037
multicellular organism growth GO:0035264 4 0.037
urogenital system development GO:0001655 97 0.035
cellular macromolecule biosynthetic process GO:0034645 224 0.035
positive regulation of rna metabolic process GO:0051254 59 0.035
axon development GO:0061564 166 0.034
regulation of rna biosynthetic process GO:2001141 213 0.034
regulation of transcription dna templated GO:0006355 213 0.034
positive regulation of epithelial cell proliferation GO:0050679 1 0.034
regulation of epithelial cell proliferation GO:0050678 3 0.033
maintenance of location GO:0051235 4 0.033
tube morphogenesis GO:0035239 349 0.033
neurological system process GO:0050877 62 0.032
organelle organization GO:0006996 227 0.032
regulation of cellular biosynthetic process GO:0031326 245 0.032
heterocycle metabolic process GO:0046483 290 0.032
proepicardium development GO:0003342 4 0.032
brain development GO:0007420 293 0.031
aromatic compound biosynthetic process GO:0019438 217 0.031
positive regulation of gene expression GO:0010628 71 0.030
regulation of biosynthetic process GO:0009889 250 0.029
hormone transport GO:0009914 2 0.028
neuron projection morphogenesis GO:0048812 161 0.028
amine metabolic process GO:0009308 2 0.028
nuclear import GO:0051170 3 0.027
digestive tract morphogenesis GO:0048546 231 0.027
lateral line system development GO:0048925 76 0.027
sensory system development GO:0048880 76 0.027
positive regulation of cellular process GO:0048522 201 0.026
regulation of developmental process GO:0050793 247 0.026
protein import into nucleus GO:0006606 3 0.026
response to chemical GO:0042221 320 0.026
development of primary female sexual characteristics GO:0046545 4 0.025
macromolecule biosynthetic process GO:0009059 227 0.025
regulation of protein transport GO:0051223 3 0.025
protein targeting to nucleus GO:0044744 3 0.025
protein import GO:0017038 3 0.025
protein localization to nucleus GO:0034504 3 0.025
gtp metabolic process GO:0046039 4 0.025
regulation of cell communication GO:0010646 232 0.024
skeletal system morphogenesis GO:0048705 102 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
positive regulation of transport GO:0051050 2 0.024
digestive system development GO:0055123 289 0.024
olfactory lobe development GO:0021988 4 0.024
endocrine pancreas development GO:0031018 27 0.023
regionalization GO:0003002 274 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
inner ear morphogenesis GO:0042472 63 0.023
gene expression GO:0010467 252 0.023
cell part morphogenesis GO:0032990 246 0.023
nucleic acid templated transcription GO:0097659 181 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
renal system development GO:0072001 94 0.022
photoreceptor cell fate commitment GO:0046552 1 0.022
regulation of response to stimulus GO:0048583 269 0.022
cellular amine metabolic process GO:0044106 2 0.021
regulation of mrna splicing via spliceosome GO:0048024 3 0.021
epidermal cell differentiation GO:0009913 36 0.021
rna biosynthetic process GO:0032774 181 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
embryonic cranial skeleton morphogenesis GO:0048701 90 0.020
hemopoiesis GO:0030097 183 0.020
nephron morphogenesis GO:0072028 2 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
cell projection morphogenesis GO:0048858 244 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
cell proliferation GO:0008283 80 0.019
positive regulation of biosynthetic process GO:0009891 68 0.019
apoptotic process involved in development GO:1902742 2 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
neuron development GO:0048666 262 0.019
cognition GO:0050890 1 0.019
regeneration GO:0031099 91 0.019
nephron tubule morphogenesis GO:0072078 1 0.019
regulation of cell activation GO:0050865 1 0.018
wound healing GO:0042060 90 0.018
ear morphogenesis GO:0042471 64 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of immune effector process GO:0002699 3 0.018
regulation of immune system process GO:0002682 34 0.018
embryonic eye morphogenesis GO:0048048 30 0.017
regulation of tube size GO:0035150 2 0.017
regulation of mrna processing GO:0050684 3 0.017
cellular protein metabolic process GO:0044267 129 0.017
multicellular organismal signaling GO:0035637 22 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
kidney development GO:0001822 92 0.017
renal tubule morphogenesis GO:0061333 1 0.017
positive regulation of transcription dna templated GO:0045893 57 0.017
negative regulation of biological process GO:0048519 304 0.017
cellular protein modification process GO:0006464 100 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
cellular ketone metabolic process GO:0042180 11 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
biosynthetic process GO:0009058 294 0.016
regulation of binding GO:0051098 3 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
chemosensory behavior GO:0007635 1 0.016
polarized epithelial cell differentiation GO:0030859 4 0.016
single organism localization GO:1902578 225 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.016
behavior GO:0007610 74 0.016
transmission of nerve impulse GO:0019226 19 0.016
establishment of localization GO:0051234 244 0.016
microtubule based process GO:0007017 60 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
nephron epithelium morphogenesis GO:0072088 1 0.015
regulation of cell shape GO:0008360 1 0.015
homeostatic process GO:0042592 142 0.015
reactive oxygen species metabolic process GO:0072593 6 0.015
organic substance biosynthetic process GO:1901576 289 0.015
regulation of gene expression GO:0010468 265 0.015
organic acid metabolic process GO:0006082 31 0.015
determination of bilateral symmetry GO:0009855 204 0.015
peptide transport GO:0015833 1 0.015
gtp catabolic process GO:0006184 2 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
neural crest cell development GO:0014032 62 0.015
response to drug GO:0042493 3 0.015
mesoderm morphogenesis GO:0048332 51 0.015
somite development GO:0061053 96 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of nervous system development GO:0051960 90 0.015
macromolecule modification GO:0043412 111 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
septum transversum development GO:0003343 4 0.015
response to monosaccharide GO:0034284 3 0.015
negative regulation of gene expression GO:0010629 65 0.015
nuclear transport GO:0051169 4 0.015
leukocyte proliferation GO:0070661 1 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
aging GO:0007568 2 0.015
taxis GO:0042330 109 0.014
stem cell maintenance GO:0019827 4 0.014
oxoacid metabolic process GO:0043436 31 0.014
mesoderm development GO:0007498 88 0.014
organelle localization GO:0051640 49 0.014
regulation of glial cell differentiation GO:0045685 4 0.014
regulation of metal ion transport GO:0010959 4 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
axis elongation GO:0003401 31 0.014
female gonad development GO:0008585 4 0.014
protein metabolic process GO:0019538 183 0.014
peripheral nervous system development GO:0007422 55 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
transport GO:0006810 220 0.013
positive regulation of cell activation GO:0050867 1 0.013
skeletal muscle organ development GO:0060538 78 0.013
regulation of blood pressure GO:0008217 1 0.013
ear development GO:0043583 127 0.013
determination of ventral identity GO:0048264 21 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
endocrine system development GO:0035270 65 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
cytoskeleton organization GO:0007010 96 0.013
appendage morphogenesis GO:0035107 56 0.013
cell projection organization GO:0030030 284 0.013
cellular component movement GO:0006928 335 0.013
positive regulation of metabolic process GO:0009893 108 0.013
positive regulation of cell cycle GO:0045787 3 0.013
hatching gland development GO:0048785 3 0.013
convergent extension GO:0060026 118 0.013
primary neural tube formation GO:0014020 1 0.013
somitogenesis GO:0001756 87 0.013
negative regulation of developmental process GO:0051093 65 0.013
pharyngeal muscle development GO:0043282 4 0.013
regulation of organ morphogenesis GO:2000027 35 0.013
regulation of sodium ion transport GO:0002028 2 0.013
negative regulation of stem cell differentiation GO:2000737 2 0.013
specification of symmetry GO:0009799 204 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
cranial ganglion development GO:0061550 3 0.012
developmental growth GO:0048589 166 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
positive regulation of developmental process GO:0051094 50 0.012
formation of primary germ layer GO:0001704 62 0.012
pronephric glomerulus morphogenesis GO:0035775 6 0.012
signal transduction GO:0007165 455 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
eye development GO:0001654 277 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
cerebellum morphogenesis GO:0021587 10 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
sensory organ morphogenesis GO:0090596 200 0.012
regulation of protein targeting GO:1903533 2 0.012
response to external stimulus GO:0009605 264 0.012
somatic stem cell maintenance GO:0035019 1 0.012
sequestering of calcium ion GO:0051208 3 0.012
metal ion transport GO:0030001 58 0.012
protein acetylation GO:0006473 2 0.012
oocyte maturation GO:0001556 4 0.012
retinoid metabolic process GO:0001523 15 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
intracellular signal transduction GO:0035556 85 0.012
single organism nuclear import GO:1902593 3 0.012
regulation of cytokine production GO:0001817 3 0.011
mesenchymal cell development GO:0014031 78 0.011
mesodermal cell differentiation GO:0048333 21 0.011
response to carbohydrate GO:0009743 3 0.011
growth GO:0040007 174 0.011
neuronal action potential GO:0019228 18 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
small molecule metabolic process GO:0044281 77 0.011
anterior posterior pattern specification GO:0009952 152 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
epidermal cell fate specification GO:0009957 4 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
muscle organ development GO:0007517 101 0.011
myelination GO:0042552 18 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
cerebellar cortex morphogenesis GO:0021696 5 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
neural crest cell differentiation GO:0014033 72 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
determination of left right symmetry GO:0007368 179 0.011
striated muscle cell development GO:0055002 108 0.011
myelin assembly GO:0032288 1 0.011
ovulation cycle GO:0042698 2 0.011
gland development GO:0048732 143 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
peripheral nervous system neuron development GO:0048935 22 0.011
hormone secretion GO:0046879 2 0.011
skin development GO:0043588 54 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
tube closure GO:0060606 1 0.011
protein homooligomerization GO:0051260 3 0.011
negative regulation of catabolic process GO:0009895 3 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
retinoic acid metabolic process GO:0042573 9 0.010
negative regulation of gliogenesis GO:0014014 1 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
cell cycle arrest GO:0007050 1 0.010
lateral line development GO:0048882 66 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
regulation of programmed cell death GO:0043067 101 0.010
cellular biosynthetic process GO:0044249 286 0.010
stem cell development GO:0048864 82 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
segmentation GO:0035282 97 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
ovulation cycle process GO:0022602 2 0.010
protein modification process GO:0036211 100 0.010
regulation of cell proliferation GO:0042127 37 0.010

tlx3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.018
kidney disease DOID:557 0 0.015
urinary system disease DOID:18 0 0.015