Danio rerio

0 known processes

btc

betacellulin, epidermal growth factor family member

btc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.095
aging GO:0007568 2 0.048
signal transduction GO:0007165 455 0.046
embryonic organ development GO:0048568 381 0.040
cellular component movement GO:0006928 335 0.037
establishment of localization GO:0051234 244 0.034
positive regulation of transport GO:0051050 2 0.034
mitochondrion organization GO:0007005 4 0.033
regulation of protein complex assembly GO:0043254 3 0.032
positive regulation of catabolic process GO:0009896 4 0.032
maintenance of location GO:0051235 4 0.032
regulation of biological quality GO:0065008 263 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
phagocytosis GO:0006909 3 0.030
positive regulation of cell cycle GO:0045787 3 0.030
transport GO:0006810 220 0.030
regulation of protein transport GO:0051223 3 0.030
gtp metabolic process GO:0046039 4 0.029
cellular component morphogenesis GO:0032989 336 0.029
single organism metabolic process GO:0044710 217 0.029
guanosine containing compound catabolic process GO:1901069 2 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.028
stem cell proliferation GO:0072089 4 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
nuclear transport GO:0051169 4 0.027
protein localization to nucleus GO:0034504 3 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
cell morphogenesis GO:0000902 289 0.027
tube morphogenesis GO:0035239 349 0.027
regulation of organelle assembly GO:1902115 4 0.026
heterocycle metabolic process GO:0046483 290 0.026
amine metabolic process GO:0009308 2 0.026
autophagy GO:0006914 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
cellular amine metabolic process GO:0044106 2 0.026
guanosine containing compound metabolic process GO:1901068 4 0.025
response to stress GO:0006950 263 0.025
cellular component assembly involved in morphogenesis GO:0010927 107 0.025
regulation of signaling GO:0023051 235 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
regulation of metabolic process GO:0019222 359 0.025
cell projection morphogenesis GO:0048858 244 0.025
cellular response to nutrient levels GO:0031669 2 0.025
single organism transport GO:0044765 206 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
gtp catabolic process GO:0006184 2 0.024
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
regulation of cell shape GO:0008360 1 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
response to drug GO:0042493 3 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
positive regulation of nucleoside metabolic process GO:0045979 1 0.023
cell projection organization GO:0030030 284 0.023
response to chemical GO:0042221 320 0.023
single organism localization GO:1902578 225 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
cell part morphogenesis GO:0032990 246 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
neurotransmitter transport GO:0006836 2 0.023
organelle organization GO:0006996 227 0.022
cellular response to starvation GO:0009267 1 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
regionalization GO:0003002 274 0.022
multicellular organism growth GO:0035264 4 0.022
cognition GO:0050890 1 0.022
atp catabolic process GO:0006200 4 0.022
cytokinesis GO:0000910 3 0.022
protein targeting to nucleus GO:0044744 3 0.022
stem cell maintenance GO:0019827 4 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.022
regulation of cytokine production GO:0001817 3 0.022
single organism nuclear import GO:1902593 3 0.022
regulation of synapse assembly GO:0051963 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
locomotion GO:0040011 313 0.021
regulation of synapse organization GO:0050807 3 0.021
single organism organelle organization GO:1902589 199 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
regulation of protein catabolic process GO:0042176 1 0.021
cellular response to light stimulus GO:0071482 4 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
endosomal transport GO:0016197 2 0.021
regulation of signal transduction GO:0009966 225 0.021
neurotransmitter secretion GO:0007269 2 0.020
cellular component biogenesis GO:0044085 178 0.020
regulation of response to stimulus GO:0048583 269 0.020
neuron differentiation GO:0030182 353 0.020
actin filament based movement GO:0030048 1 0.020
brain development GO:0007420 293 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
central nervous system development GO:0007417 387 0.020
generation of neurons GO:0048699 385 0.020
regulation of cell projection assembly GO:0060491 4 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
digestive tract morphogenesis GO:0048546 231 0.020
small molecule metabolic process GO:0044281 77 0.020
regulation of binding GO:0051098 3 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
protein import GO:0017038 3 0.020
nuclear import GO:0051170 3 0.019
protein polymerization GO:0051258 4 0.019
regulation of cell communication GO:0010646 232 0.019
determination of bilateral symmetry GO:0009855 204 0.019
cell migration GO:0016477 237 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
meiotic nuclear division GO:0007126 4 0.019
chemosensory behavior GO:0007635 1 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
transmembrane transport GO:0055085 120 0.019
membrane invagination GO:0010324 1 0.019
immune system process GO:0002376 241 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
cellular component assembly GO:0022607 170 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
gastrulation GO:0007369 208 0.019
lipid storage GO:0019915 1 0.019
positive regulation of biological process GO:0048518 253 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
protein import into nucleus GO:0006606 3 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
eye development GO:0001654 277 0.018
digestive tract development GO:0048565 265 0.018
neuroblast proliferation GO:0007405 2 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
gene expression GO:0010467 252 0.018
positive regulation of cellular process GO:0048522 201 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
cell matrix adhesion GO:0007160 4 0.018
secondary metabolic process GO:0019748 3 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.017
organic acid metabolic process GO:0006082 31 0.017
biosynthetic process GO:0009058 294 0.017
sensory organ development GO:0007423 393 0.017
localization of cell GO:0051674 244 0.017
organelle fusion GO:0048284 3 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
cellular component disassembly GO:0022411 1 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
protein localization to plasma membrane GO:0072659 1 0.017
digestive system development GO:0055123 289 0.017
immune system development GO:0002520 191 0.017
muscle structure development GO:0061061 196 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
camera type eye development GO:0043010 222 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
regulation of metal ion transport GO:0010959 4 0.017
response to uv GO:0009411 3 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
sensory organ morphogenesis GO:0090596 200 0.017
rna localization GO:0006403 4 0.017
nucleic acid metabolic process GO:0090304 244 0.017
aromatic compound biosynthetic process GO:0019438 217 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
cilium organization GO:0044782 71 0.016
negative regulation of biological process GO:0048519 304 0.016
negative regulation of cellular process GO:0048523 283 0.016
meiotic cell cycle process GO:1903046 3 0.016
adult behavior GO:0030534 2 0.016
macroautophagy GO:0016236 1 0.016
cell substrate adhesion GO:0031589 4 0.016
organelle assembly GO:0070925 110 0.016
response to organic substance GO:0010033 153 0.016
single organism membrane fusion GO:0044801 2 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
response to external stimulus GO:0009605 264 0.016
phagocytosis engulfment GO:0006911 1 0.016
multi organism cellular process GO:0044764 2 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
hormone secretion GO:0046879 2 0.016
cellular biosynthetic process GO:0044249 286 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
neuron development GO:0048666 262 0.015
system process GO:0003008 185 0.015
liver development GO:0001889 96 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
heart development GO:0007507 313 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
regulation of muscle contraction GO:0006937 3 0.015
amino acid transport GO:0006865 2 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
homeostatic process GO:0042592 142 0.015
head development GO:0060322 303 0.015
synaptic vesicle localization GO:0097479 1 0.015
response to hexose GO:0009746 3 0.015
protein acetylation GO:0006473 2 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
neuron projection morphogenesis GO:0048812 161 0.015
positive regulation of secretion GO:0051047 1 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
exocytosis GO:0006887 1 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
regulation of primary metabolic process GO:0080090 311 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of striated muscle contraction GO:0006942 2 0.015
cell motility GO:0048870 244 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
leukocyte proliferation GO:0070661 1 0.015
rna metabolic process GO:0016070 219 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
female sex differentiation GO:0046660 4 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
wound healing GO:0042060 90 0.014
growth GO:0040007 174 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.014
post embryonic organ development GO:0048569 4 0.014
rna transport GO:0050658 2 0.014
organic substance biosynthetic process GO:1901576 289 0.014
regulation of protein targeting GO:1903533 2 0.014
oxoacid metabolic process GO:0043436 31 0.014
lamellipodium organization GO:0097581 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
compound eye development GO:0048749 2 0.014
vasculature development GO:0001944 278 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
monoamine transport GO:0015844 1 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
renal tubule morphogenesis GO:0061333 1 0.014
membrane fusion GO:0061025 2 0.014
protein metabolic process GO:0019538 183 0.014
cilium assembly GO:0042384 58 0.014
retina development in camera type eye GO:0060041 146 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
locomotor rhythm GO:0045475 3 0.014
peptidyl serine modification GO:0018209 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.013
cilium morphogenesis GO:0060271 85 0.013
response to carbohydrate GO:0009743 3 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
spermatid development GO:0007286 2 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
lateral inhibition GO:0046331 1 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of inflammatory response GO:0050727 2 0.013
regulation of wound healing GO:0061041 2 0.013
regulation of developmental process GO:0050793 247 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
response to alkaloid GO:0043279 2 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of protein binding GO:0043393 3 0.013
centrosome organization GO:0051297 1 0.013
macromolecular complex disassembly GO:0032984 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
protein complex disassembly GO:0043241 1 0.013
developmental programmed cell death GO:0010623 4 0.013
response to wounding GO:0009611 116 0.013
specification of symmetry GO:0009799 204 0.013
regulation of circadian rhythm GO:0042752 4 0.013
gland development GO:0048732 143 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
regulation of gtpase activity GO:0043087 2 0.013
peptide transport GO:0015833 1 0.013
cellular protein catabolic process GO:0044257 4 0.013
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.013
hemopoiesis GO:0030097 183 0.013
cardiac atrium development GO:0003230 4 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
regulation of gene expression GO:0010468 265 0.013
meiotic chromosome segregation GO:0045132 3 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
sleep GO:0030431 1 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
female gonad development GO:0008585 4 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
heart looping GO:0001947 94 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
phosphorus metabolic process GO:0006793 109 0.012
glucose homeostasis GO:0042593 1 0.012
lipid catabolic process GO:0016042 4 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
actin filament polymerization GO:0030041 2 0.012
regulation of mrna processing GO:0050684 3 0.012
response to monosaccharide GO:0034284 3 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
regulation of blood vessel size GO:0050880 2 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
heart morphogenesis GO:0003007 156 0.012
response to abiotic stimulus GO:0009628 122 0.012
hormone transport GO:0009914 2 0.012
response to corticosteroid GO:0031960 1 0.012
regulation of autophagy GO:0010506 3 0.012
tube closure GO:0060606 1 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
protein secretion GO:0009306 1 0.012
er nucleus signaling pathway GO:0006984 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of organ growth GO:0046620 3 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.012
blood vessel morphogenesis GO:0048514 216 0.012
negative regulation of catabolic process GO:0009895 3 0.012
wnt signaling pathway GO:0016055 80 0.012
negative regulation of defense response GO:0031348 2 0.012
b cell activation GO:0042113 2 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
chordate embryonic development GO:0043009 271 0.012
anterior posterior pattern specification GO:0009952 152 0.012
cellular localization GO:0051641 97 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.011
translational initiation GO:0006413 3 0.011
protein homooligomerization GO:0051260 3 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
determination of left right symmetry GO:0007368 179 0.011
ear development GO:0043583 127 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
nucleic acid transport GO:0050657 2 0.011
protein modification process GO:0036211 100 0.011
intracellular signal transduction GO:0035556 85 0.011
somatic stem cell maintenance GO:0035019 1 0.011
cellular response to radiation GO:0071478 4 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
viral process GO:0016032 1 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
positive regulation of metabolic process GO:0009893 108 0.011
mononuclear cell proliferation GO:0032943 1 0.011
regulation of calcium ion transport GO:0051924 2 0.011
neurological system process GO:0050877 62 0.011
developmental growth GO:0048589 166 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
response to light stimulus GO:0009416 46 0.011
negative regulation of protein transport GO:0051224 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
activation of mapk activity GO:0000187 3 0.011
response to unfolded protein GO:0006986 2 0.011
transcription dna templated GO:0006351 181 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
ion transport GO:0006811 114 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
muscle cell differentiation GO:0042692 139 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
lateral line system development GO:0048925 76 0.011
cell substrate junction assembly GO:0007044 2 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
sequestering of metal ion GO:0051238 3 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
response to topologically incorrect protein GO:0035966 2 0.011
centrosome cycle GO:0007098 1 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
nuclear migration GO:0007097 3 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
axon development GO:0061564 166 0.011
positive regulation of multi organism process GO:0043902 3 0.011
mechanosensory behavior GO:0007638 2 0.011
phototransduction GO:0007602 2 0.011
cortical cytoskeleton organization GO:0030865 1 0.010
muscle cell development GO:0055001 115 0.010
action potential GO:0001508 19 0.010
apoptotic process GO:0006915 116 0.010
regulation of tube size GO:0035150 2 0.010
axonogenesis GO:0007409 152 0.010
nephron morphogenesis GO:0072028 2 0.010
regulation of catalytic activity GO:0050790 55 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
ovulation cycle process GO:0022602 2 0.010
melanin metabolic process GO:0006582 2 0.010
multicellular organismal signaling GO:0035637 22 0.010
regulation of biosynthetic process GO:0009889 250 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
regulation of molecular function GO:0065009 70 0.010
apoptotic process involved in development GO:1902742 2 0.010
protein dephosphorylation GO:0006470 3 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
cellular amide metabolic process GO:0043603 4 0.010
regulation of transporter activity GO:0032409 2 0.010
regulation of protein polymerization GO:0032271 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
neuronal action potential GO:0019228 18 0.010
adherens junction organization GO:0034332 4 0.010
cell cycle g2 m phase transition GO:0044839 4 0.010
cell projection assembly GO:0030031 64 0.010
striated muscle cell differentiation GO:0051146 129 0.010
golgi vesicle transport GO:0048193 3 0.010
actin mediated cell contraction GO:0070252 1 0.010
rhombomere 6 development GO:0021572 4 0.010
transmission of nerve impulse GO:0019226 19 0.010

btc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.021
cardiovascular system disease DOID:1287 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
disease of metabolism DOID:0014667 0 0.011
retinal disease DOID:5679 0 0.010